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Menglu Yang, M.D., Ph.D.

Title
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Department
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Biography
Peking University Health Science Center, Beijing, ChinaMD06/2014Clinical Medicine
Peking University Health Science Center, Beijing, ChinaPhD07/2017Ophthalmology
Schepens Eye Research Institute, Boston, MAPostdoc04/2021Ophthalmology

Overview
My research focus lies in restoring homeostasis to the ocular surface across various diseases. Leveraging my clinical expertise and scientific approach, I aim to advance the understanding and treatment of ocular surface diseases, especially corneal nerve degeneration. In addition, I am a passionate educator, teaching medical students as the course director of Intermediate Medical Mandarin at Harvard Medical School, and I mentor graduate and undergraduate students for their science projects. Locally, I chair the Working Progress Feedback committee at Schepens, and I am a member of the Sex/gender Informed Research Collaborative Thinktank, and serve its Advisory committee. Nationally, I serve on committees for national research societies and organize conferences including the Association for Research in Vision and Ophthalmology (ARVO) and the American Society for Investigative Pathology (ASIP). Internationally I serve on committees for the International Society for Eye Research (ISER) and I serve on the editorial board for peer reviewed journals.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. HT94252410788 (Menglu Yang) Sep 1, 2024 - Aug 31, 2026
    DOD/CDMRP
    Non-invasive Transpalpebral Electrical Stimulation as a Therapy for Combat-Related Corneal Trauma
    Role Description: Our goal is to shorten the corneal wound healing time, reduce the inflammation and scar formation while attenuating the ocular pain in both non-penetrating and penetrating corneal injuries using TpES.
    Role: PI
  2. (Menglu Yang) Apr 1, 2024 - Mar 30, 2025
    The Connors Center IGNITE Award Program
    Tear Exosome DNA as Novel Biomarkers for Sjogren’s Syndrome
    Role Description: Our goal is to understand the causal relationship between exoDNA and SS, to identify promising biomarkers and therapeutic targets for the diagnosis, monitoring, and treatment of SS
    Role: PI of multi-PI project
  3. (Menglu Yang) Aug 1, 2023 - Jul 31, 2024
    Massachusetts Lions Eye Research Fund
    BMP-7 as a novel therapeutic to combat proliferative vitreoretinopathy
    Role Description: In this study, we will test whether BMP-7 can block the scarring capacity of TGFß in a cell culture model of primary human fetal RPE as well as a mouse model of PVR.
    Role: PI of a multi-PI project
  4. (Menglu Yang) Jan 1, 2023 - Dec 31, 2023
    Grimshaw-Gudewiz Charitable Foundation
    Microcurrent Electrical Stimulation as a Therapy for Angiogenesis in Age Related Macular Degneration
    Role Description: The goal is to determine the role of electrical stimulation as a therapy for age-related macular degeneration
    Role: PI

Bibliographic
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.