Harvard Catalyst Profiles

Icahn School of Medicine at Mount Sinai, New York, NY	MD	05/2015	Medicine
Mount Sinai School of Medicine, New York, NY	MPH	05/2013	Epidemiology and Biostatistics
Dartmouth College, Hanover NH	BA	06/2007	Ecology and Evolutionary Biology
Beth Israel Deaconess Medical Center, Boston, MA		06/2018	Internal Medicine Residency
Beth Israel Deaconess Medical Center, Boston, MA		12/2021	Nephrology Fellowship

My research is focused on exploring the pathophysiology underlying emerging and environmentally-mediated kidney diseases, and on using these physiologic understandings to develop and apply improved prevention and treatment regimens. In addition to my MD training, I hold a master’s degree in public health with a focus on epidemiology and biostatistics. Much of my work to date has revolved around Mesoamerican Nephropathy (MeN). I was principal investigator and first author for one of the early prevalence studies on MeN in a hotspot region in Central America, and have since led research to determine the accuracy of kidney function estimating equations in CKDnT populations. My current work focuses on metabolic features of MeN, supported by a Doris Duke Physician Scientist Fellowship award, and more broadly on the application of "omics" methodologies to understand MeN pathophysiology. I am a member of the board of directors of La Isla Network, a nonprofit devoted to CKDnt research which is responsible for the creation and study of the first protocols designed to prevent the onset of MeN. I am also a founding member and current board co-chairperson for the Consortium on the Epidemic of Nephropathy in Central America and Mexico (CENCAM), the principal international society of researchers focused on the disease. Outside MeN, I study metabolic alterations and therapies in patients with COVID-19 associated acute kidney injury, and study kidney injury, electrolytes, and acid base disorders in critically ill patients using bioinformatics approaches.

• Chronic Kidney Disease
• Acute Kidney Injury
• Mesoamerican Nephropathy
• Chronic Kidney Disease of Undetermined Etiology (CKDu)
• Chronic Kidney Disease of Nontraditional Etiology (CKDnt)
• Bioinformatics
• Metabolomics