Harvard Catalyst Profiles

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Seth M. Bloom, M.D., Ph.D.

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Biography
education and training
Washington University, St. Louis, MO, USABA05/2004Biology
Washington University School of Medicine, St. Louis, MO, USAMD, PhD05/2012Medicine and Microbiology
Barnes-Jewish Hospital & Washington University, St. Louis, MO, USA06/2015Internal Medicine (residency)
Massachusetts General Hospital and Brigham & Women's Hospital, Boston, MA, USA07/2017Infectious Diseases (fellowship)

Overview
overview
I am an Infectious Disease physician-scientist at Massachusetts General Hospital and Instructor in Medicine at HMS doing research at the Ragon Institute of MGH, MIT, and Harvard. I study how the cervicovaginal microbiota and metabolome influence genital tract health, mucosal immunity, and risk for diseases such as HIV, bacterial vaginosis, and cervical cancer. I seek to elucidate basic mechanisms of disease and identify new therapies to modify microbiota composition. This research is broadly relevant for genital tract health but holds particular importance for many African populations, which face particularly high burden of key microbiota-associated diseases.
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Research
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  1. K08AI171166 (BLOOM, SETH MICHAEL) Feb 17, 2023 - Jan 31, 2028
    NIH
    Mechanistic characterization of vaginal microbiome-metabolome associations and metabolite-mediated host inflammation
    Role: Principal Investigator

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© 2024 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.