David Chung | Harvard Catalyst Profiles

David Young Chung, M.D.,Ph.D.

Title

Assistant Professor of Neurology

Institution

Massachusetts General Hospital

Department

Neurology

Address

Massachusetts General Hospital
Department of Neurology, CNY 149
149 13th Street
Charlestown MA 02129

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research activities and funding|

Featured Videos

Optogenetic cortical spreading depolarizations
Dynamic cerebral blood volume following subarachnoid hemorrhage

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Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Displaying 25 of 58 total Publications Show all

Piedmont J, Chung D, Webb A. Association of SSRI and SNRI use with incident hyponatremia after subarachnoid hemorrhage. Clin Neurol Neurosurg. 2024 Dec 03; 249:108671. PMID: 39662379.
Citations:
Fields: NeuNeurology NeuNeurosurgery
Alves CRR, Das S, Krishnan V, Ha LL, Fox LR, Stutzman HE, Shamber CE, Kalailingam P, McCarthy S, Lino Cardenas CL, Fong CE, Imai T, Mitra S, Yun S, Wood RK, Benning FMC, Lawton J, Kim N, Silverstein RA, da Silva JF, de la Cruz D, Richa R, Malhotra R, Chung DY, Chao LH, Tsai SQ, Maguire CA, Lindsay ME, Kleinstiver BP, Musolino PL. In vivo Treatment of a Severe Vascular Disease via a Bespoke CRISPR-Cas9 Base Editor. bioRxiv. 2024 Nov 11. PMID: 39605323; PMCID: PMC11601241.
Citations:
Nishimoto T, Oka F, Inoue T, Moriyama H, Kawano R, Suzuki M, Chung DY, Ayata C, Ishihara H. Impact of intracranial hypertension and cerebral perfusion pressure on spreading depolarization. J Cereb Blood Flow Metab. 2024 Nov 05; 271678X241296799. PMID: 39501698; PMCID: PMC11563493.
Citations:
Fields: BraBrain MetMetabolism VasVascular Diseases
Cobler-Lichter M, Suchdev K, Tatro H, Cascone A, Yang J, Weinberg J, Abdalkader MK, Dasenbrock HH, Ong CJ, Cervantes-Arslanian A, Greer D, Nguyen TN, Daneshmand A, Chung DY. Safety and Outcomes of Valproic Acid in Subarachnoid Hemorrhage Patients: A Retrospective Study. medRxiv. 2024 Sep 10. PMID: 39314927; PMCID: PMC11419238.
Citations:
Sugimoto K, Chung DY, Fischer P, Takizawa T, Qin T, Yaseen MA, Sakadžic S, Ayata C. Optogenetic Functional Activation Is Detrimental During Acute Ischemic Stroke in Mice. Stroke. 2024 Oct; 55(10):2502-2509. PMID: 39234742; PMCID: PMC11421960.
Citations:
Fields: BraBrain VasVascular DiseasesTranslation:Animals Cells
Jin X, Imai T, Morais A, Sasaki Y, Chung DY, Ayata C. Hippocampal infarction and generalized seizures predict early mortality after endovascular middle cerebral artery occlusion in mice. Exp Neurol. 2024 Oct; 380:114903. PMID: 39079623; PMCID: PMC11347107.
Citations:
Fields: NeuNeurologyTranslation:Animals
Rodriguez Lara F, Sunkavalli P, Mikaelian M, Golemb B, Chung DY, Duhaime AC, Staley K, Costine-Bartell B. Brief apnea with hypoventilation reduces seizure duration and shifts seizure location for several hours in a model of severe traumatic brain injury. Epilepsia. 2024 Jul; 65(7):2099-2110. PMID: 38752982; PMCID: PMC11251852.
Citations: 1
Fields: BraBrain NeuNeurologyTranslation:Animals
Fischer P, Tamim I, Sugimoto K, Morais A, Imai T, Takizawa T, Qin T, Schlunk F, Endres M, Yaseen MA, Chung DY, Sakadzic S, Ayata C. Spreading Depolarizations Suppress Hematoma Growth in Hyperacute Intracerebral Hemorrhage in Mice. Stroke. 2023 10; 54(10):2640-2651. PMID: 37610105; PMCID: PMC10530404.
Citations: 3
Fields: BraBrain VasVascular DiseasesTranslation:Animals
Hingorani KS, Barnes E, Carneiro T, Sader E, Anand P, Ong CJ, Chung D, Daneshmand A, Suchdev K, Takahashi C, Greer D, Shulman JG, Aparicio HJ, Nguyen TN, Romero JR, AbdalKader M, Feske SK, Kimmel SD, Weinstein ZM, Fagan M, Dobrilovic N, Awtry E, Cervantes-Arslanian AM. Strokes in Patients With Injection Drug Use and Tricuspid Valve Endocarditis - A Case Series. Neurohospitalist. 2023 Jul; 13(3):272-277. PMID: 37441214; PMCID: PMC10334046.
Citations:
Sugimoto K, Yang J, Fischer P, Takizawa T, Mulder IA, Qin T, Erdogan TD, Yaseen MA, Sakadžic S, Chung DY, Ayata C. Optogenetic Spreading Depolarizations Do Not Worsen Acute Ischemic Stroke Outcome. Stroke. 2023 04; 54(4):1110-1119. PMID: 36876481; PMCID: PMC10050120.
Citations: 6
Fields: BraBrain VasVascular DiseasesTranslation:Animals
Aykan SA, Xie H, Zheng Y, Chung DY, Kura S, Han Lai J, Erdogan TD, Morais A, Tamim I, Yagmur D, Ishikawa H, Arai K, Abbas Yaseen M, Boas DA, Sakadzic S, Ayata C. Rho-Kinase Inhibition Improves the Outcome of Focal Subcortical White Matter Lesions. Stroke. 2022 07; 53(7):2369-2376. PMID: 35656825; PMCID: PMC9245195.
Citations:
Fields: BraBrain VasVascular DiseasesTranslation:Humans Animals
Chan WP, Prescott BR, Barra ME, Chung DY, Kim IS, Saglam H, Hutch MR, Shin M, Zafar SF, Benjamin EJ, Smirnakis SM, Dupuis J, Greer DM, Ong CJ. Dexmedetomidine and Other Analgosedatives Alter Pupil Characteristics in Critically Ill Patients. Crit Care Explor. 2022 May; 4(5):e0691. PMID: 35783547; PMCID: PMC9243241.
Citations: 2
Oka F, Lee JH, Yuzawa I, Li M, von Bornstaedt D, Eikermann-Haerter K, Qin T, Chung DY, Sadeghian H, Seidel JL, Imai T, Vuralli D, Platt RM, Nelson MT, Joutel A, Sakadzic S, Ayata C. CADASIL mutations sensitize the brain to ischemia via spreading depolarizations and abnormal extracellular potassium homeostasis. J Clin Invest. 2022 04 15; 132(8). PMID: 35202003; PMCID: PMC9012276.
Citations: 5
Fields: MedMedicine (General)Translation:Animals
Mosley N, Chung JY, Jin G, Franceschini MA, Whalen MJ, Chung DY. Cortical Spreading Depolarization, Blood Flow, and Cognitive Outcomes in a Closed Head Injury Mouse Model of Traumatic Brain Injury. Neurocrit Care. 2022 06; 37(Suppl 1):102-111. PMID: 35378664; PMCID: PMC9262867.
Citations: 3
Fields: CriCritical Care NeuNeurologyTranslation:Humans Animals
Lai JH, Qin T, Sakadžic S, Ayata C, Chung DY. Correction to: Cortical Spreading Depolarizations in a Mouse Model of Subarachnoid Hemorrhage. Neurocrit Care. 2022 Apr; 36(2):689. PMID: 35041114.
Citations:
Fields: CriCritical Care NeuNeurology
Sivakumar S, Tsetsou S, Patel AB, Stapleton CJ, Grannan BL, Schweitzer JS, Chung DY, Rosenthal ES. Cortical Spreading Depolarizations and Clinically Measured Scalp EEG Activity After Aneurysmal Subarachnoid Hemorrhage and Traumatic Brain Injury. Neurocrit Care. 2022 06; 37(Suppl 1):49-59. PMID: 34997536; PMCID: PMC9810077.
Citations: 2
Fields: CriCritical Care NeuNeurologyTranslation:Humans
Lai JH, Qin T, Sakadžic S, Ayata C, Chung DY. Cortical Spreading Depolarizations in a Mouse Model of Subarachnoid Hemorrhage. Neurocrit Care. 2022 06; 37(Suppl 1):123-132. PMID: 34981426; PMCID: PMC9250554.
Citations: 2
Fields: CriCritical Care NeuNeurologyTranslation:Animals
Aykan SA, Xie H, Lai JH, Zheng Y, Chung DY, Kura S, Anzabi M, Sugimoto K, McAllister LM, Yaseen MA, Boas DA, Whalen MJ, Sakadzic S, Ayata C. Focal Subcortical White Matter Lesions Disrupt Resting State Cortical Interhemispheric Functional Connectivity in Mice. Cereb Cortex. 2021 10 01; 31(11):4958-4969. PMID: 34037216; PMCID: PMC8491690.
Citations: 1
Fields: BraBrainTranslation:Humans Animals
Chung DY, Thompson BB, Kumar MA, Mahta A, Rao SS, Lai JH, Tadevosyan A, Kessler K, Locascio JJ, Patel AB, Mohamed W, Olson DM, John S, Rordorf GA. Association of External Ventricular Drain Wean Strategy with Shunt Placement and Length of Stay in Subarachnoid Hemorrhage: A Prospective Multicenter Study. Neurocrit Care. 2022 04; 36(2):536-545. PMID: 34498207; PMCID: PMC9128519.
Citations: 18
Fields: CriCritical Care NeuNeurologyTranslation:Humans
Bernier TD, Schontz MJ, Izzy S, Chung DY, Nelson SE, Leslie-Mazwi TM, Henderson GV, Dasenbrock H, Patel N, Aziz-Sultan MA, Feske S, Du R, Abulhasan YB, Angle MR. Treatment of Subarachnoid Hemorrhage-associated Delayed Cerebral Ischemia With Milrinone: A Review and Proposal. J Neurosurg Anesthesiol. 2021 Jul 01; 33(3):195-202. PMID: 33480639; PMCID: PMC8192346.
Citations: 9
Fields: AneAnesthesiology NeuNeurosurgeryTranslation:Humans
Tamim I, Chung DY, de Morais AL, Loonen ICM, Qin T, Misra A, Schlunk F, Endres M, Schiff SJ, Ayata C. Spreading depression as an innate antiseizure mechanism. Nat Commun. 2021 04 13; 12(1):2206. PMID: 33850125; PMCID: PMC8044138.
Citations: 25
Fields: BioBiology SciScienceTranslation:Animals
Chung DY, Abdalkader M, Nguyen TN. Aneurysmal Subarachnoid Hemorrhage. Neurol Clin. 2021 05; 39(2):419-442. PMID: 33896527; PMCID: PMC8147706.
Citations: 13
Fields: NeuNeurologyTranslation:Humans
Takahashi CE, Virmani D, Chung DY, Ong C, Cervantes-Arslanian AM. Blunt and Penetrating Severe Traumatic Brain Injury. Neurol Clin. 2021 05; 39(2):443-469. PMID: 33896528.
Citations: 7
Fields: NeuNeurologyTranslation:Humans
Abdalkader M, Sathya A, Ma A, Cervantes-Arslanian AM, Chung DY, Barest G, Nguyen TN. Hydrophilic polymer embolization following flow diversion of cerebral aneurysms. Neuroradiol J. 2021 Aug; 34(4):363-369. PMID: 33765885; PMCID: PMC8447820.
Citations:
Fields: NeuNeurology RadRadiologyTranslation:Humans
Nguyen TN, Haussen DC, Qureshi MM, Yamagami H, Fujinaka T, Mansour OY, Abdalkader M, Frankel M, Qiu Z, Taylor A, Lylyk P, Eker OF, Mechtouff L, Piotin M, Lima FO, Mont'Alverne F, Izzath W, Sakai N, Mohammaden M, Al-Bayati AR, Renieri L, Mangiafico S, Ozretic D, Chalumeau V, Ahmad S, Rashid U, Hussain SI, John S, Griffin E, Thornton J, Fiorot JA, Rivera R, Hammami N, Cervantes-Arslanian AM, Dasenbrock HH, Vu HL, Nguyen VQ, Hetts S, Bourcier R, Guile R, Walker M, Sharma M, Frei D, Jabbour P, Herial N, Al-Mufti F, Ozdemir AO, Aykac O, Gandhi D, Chugh C, Matouk C, Lavoie P, Edgell R, Beer-Furlan A, Chen M, Killer-Oberpfalzer M, Pereira VM, Nicholson P, Huded V, Ohara N, Watanabe D, Shin DH, Magalhaes PS, Kikano R, Ortega-Gutierrez S, Farooqui M, Abou-Hamden A, Amano T, Yamamoto R, Weeks A, Cora EA, Sivan-Hoffmann R, Crosa R, Möhlenbruch M, Nagel S, Al-Jehani H, Sheth SA, Lopez Rivera VS, Siegler JE, Sani AF, Puri AS, Kuhn AL, Bernava G, Machi P, Abud DG, Pontes-Neto OM, Wakhloo AK, Voetsch B, Raz E, Yaghi S, Mehta BP, Kimura N, Murakami M, Lee JS, Hong JM, Fahed R, Walker G, Hagashi E, Cordina SM, Roh HG, Wong K, Arenillas JF, Martinez-Galdamez M, Blasco J, Rodriguez Vasquez A, Fonseca L, Silva ML, Wu TY, John S, Brehm A, Psychogios M, Mack WJ, Tenser M, Todaka T, Fujimura M, Novakovic R, Deguchi J, Sugiura Y, Tokimura H, Khatri R, Kelly M, Peeling L, Murayama Y, Winters HS, Wong J, Teleb M, Payne J, Fukuda H, Miyake K, Shimbo J, Sugimura Y, Uno M, Takenobu Y, Matsumaru Y, Yamada S, Kono R, Kanamaru T, Morimoto M, Iida J, Saini V, Yavagal D, Bushnaq S, Huang W, Linfante I, Kirmani J, Liebeskind DS, Szeder V, Shah R, Devlin TG, Birnbaum L, Luo J, Churojana A, Masoud HE, Lopez CY, Steinfort B, Ma A, Hassan AE, Al Hashmi A, McDermott M, Mokin M, Chebl A, Kargiotis O, Tsivgoulis G, Morris JG, Eskey CJ, Thon J, Rebello L, Altschul D, Cornett O, Singh V, Pandian J, Kulkarni A, Lavados PM, Olavarria VV, Todo K, Yamamoto Y, Silva GS, Geyik S, Johann J, Multani S, Kaliaev A, Sonoda K, Hashimoto H, Alhazzani A, Chung DY, Mayer SA, Fifi JT, Hill MD, Zhang H, Yuan Z, Shang X, Castonguay AC, Gupta R, Jovin TG, Raymond J, Zaidat OO, Nogueira RG, SVIN COVID-19 Registry, the Middle East North Africa Stroke and Interventional Neurotherapies Organi, Japanese Society of Vascular and Interventional Neurology Society (JVIN). Decline in subarachnoid haemorrhage volumes associated with the first wave of the COVID-19 pandemic. Stroke Vasc Neurol. 2021 12; 6(4):542-552. PMID: 33771936; PMCID: PMC8006491.
Citations: 24
Fields: NeuNeurology VasVascular DiseasesTranslation:Humans Cells PHPublic Health

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