Harvard Catalyst Profiles

Nanjing Medical University, China	PHD,MD	06/2013	Immunotherapy for MDR-TB,Pulmonary and Critical Care Medicine
Jiangsu Province Hospital, China	Residency	09/2016	Pulmonary and Critical Care Medicine
University of Massachusetts Medical School, US	Postdoc research associate	10/2019	Immune Control in Limiting pulmonary Tuberculosis Infection
Harvard Medical School, US	research fellow	10/2020	Epidemiology on Tuberculosis and Pandemic in global health

As a former pulmonologist and clinical researcher specializing in lung infectious diseases and tuberculosis (TB), I bring ten years of experience managing both outpatients and inpatients in pulmonary and critical care medicine. My expertise spans a wide range of diagnostic and therapeutic modalities for pulmonary diseases, guided by chest imaging techniques such as chest X-rays and CT scans.
Between 2009 and 2020, I was dedicated in national-level multicenter clinical trials in China, focusing on developing host-directed therapy strategies combined with shortened multi-drug-resistant TB (MDR-TB) regimens. My research aimed to investigate the impact of these novel adjunct therapies on immune response and clinical efficacy. Over the past decade, I studied the immunomodulation of Th1/Th17 balance, mechanisms of CD4 T cell exhaustion in response to drug-resistant Mycobacterium tuberculosis strains, and the detection of prognostic biomarkers.
Since 2020, I have been working at Harvard Medical School with Dr. Megan Murray’s multidisciplinary global health TB research team. Our longitudinal cohort study in Peru, conducted in collaboration with Socios En Salud Peru, evaluated chest imaging in TB patients and their household contacts within two large cohorts totaling over 15,000 participants. This work aims to develop strategies for early TB detection and treatment among individuals exposed to TB, thereby interrupting potential transmission.

• MDR-TB
• Tuberculosis
• Pulmonology
• Global Health