DR134DraganaRoguljaDragana Rogulja, Ph.D.108285Rogulja, Dragana617/432-1772Associate Professor of Neurobiologycatalyst:eCommonsLogineCommons Loginprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:address2address line 2vivo:address3address line 3vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsvivo:phoneNumberphonePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofvivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 101487218694569Rogulja D, Rauskolb C, Irvine KDDevelopmental cellMorphogen control of wing growth through the Fat signaling pathway. Dev Cell. 2008 Aug; 15(2):309-21.Dev Cell2008-08-01T00:00:002008Morphogen control of wing growth through the Fat signaling pathway.Authorship 1082250429983326Zhang SX, Miner LE, Boutros CL, Rogulja D, Crickmore MANeuronMotivation, Perception, and Chance Converge to Make a Binary Decision. Neuron. 2018 07 25; 99(2):376-388.e6.Neuron2018-07-05T00:00:002018Motivation, Perception, and Chance Converge to Make a Binary Decision.22461610Rogulja D, Young MWScience (New York, N.Y.)Control of sleep by cyclin A and its regulator. Science. 2012 Mar 30; 335(6076):1617-21.Science2012-03-30T00:00:002012Control of sleep by cyclin A and its regulator.12850143Yuzenkova J, Nechaev S, Berlin J, Rogulja D, Kuznedelov K, Inman R, Mushegian A, Severinov KJournal of molecular biologyGenome of Xanthomonas oryzae bacteriophage Xp10: an odd T-odd phage. J Mol Biol. 2003 Jul 18; 330(4):735-48.J Mol Biol2003-07-18T00:00:002003Genome of Xanthomonas oryzae bacteriophage Xp10: an odd T-odd phage.D012892DisordersPhenomena2988310.59216Sleep DeprivationD012890Physiology106045960.316774SleepD029721Chemicals & Drugs56316970.497893Drosophila ProteinsD012726Activities & Behaviors711120.912984Sexual Behavior, AnimalD001143Physiology48311640.630174ArousalGeneticsMedicineNeurobiologySleep MedicineBrigham and Women's HospitalHarvard Medical SchoolSWL5StevenLockleySteven W. Lockley, Ph.D.42.33710500000000-71.1023170000000059875Lockley, StevenAssociate Professor of Medicine, Part-timeCAC5CharlesCzeislerCharles Andrew Czeisler, M.D., Ph.D.42.33710500000000-71.1023170000000024237Czeisler, CharlesFrank Baldino, Jr., Ph.D. Professor of Sleep MedicineSR165SusanRedlineSusan Redline, M.D.42.33710500000000-71.1023170000000027634Redline, SusanPeter C. Farrell Professor of Sleep MedicineMEG4MichaelGreenbergMichael Eldon Greenberg, Ph.D.42.33602040000000-71.1034325000000080338Greenberg, MichaelNathan Marsh Pusey Professor of NeurobiologyOM26OferMazorOfer Mazor, Ph.D.99393Mazor, OferInstructor in NeurobiologyMIK1MitziKurodaMitzi Kuroda, Ph.D.42.33837200000000-71.1032690000000065836Kuroda, MitziProfessor of GeneticsNP7NorbertPerrimonNorbert Perrimon, Ph.D.42.33837200000000-71.103269000000006247Perrimon, NorbertJames Stillman Professor of Developmental Biology1122selected publications0.859950.00494815106research areas1.320630.013464913coauthor of46.8622.6268860similar toAuthorship 1188065231474539Zhang SX, Rogulja D, Crickmore MACurrent biology : CBRecurrent Circuitry Sustains Drosophila Courtship Drive While Priming Itself for Satiety. Curr Biol. 2019 10 07; 29(19):3216-3228.e9.Curr Biol2019-08-29T00:00:002019Recurrent Circuitry Sustains Drosophila Courtship Drive While Priming Itself for Satiety.true1James Stillman Professor of Developmental BiologyJames Stillman Professor of Developmental BiologyAuthorship 1206815431786014Thornquist SC, Langer K, Zhang SX, Rogulja D, Crickmore MANeuronCaMKII Measures the Passage of Time to Coordinate Behavior and Motivational State. Neuron. 2020 01 22; 105(2):334-345.e9.Neuron2019-11-27T00:00:002019CaMKII Measures the Passage of Time to Coordinate Behavior and Motivational State.AJ212AlenJuginovicAlen Juginovic, M.D.187356Juginovic, AlenResearch Fellow in Neurobiology2021-06-30ROGULJA, DRAGANA2016-09-30Mechanisms of arousal threshold and sleep homeostasisDP2AT009498Principal InvestigatorAuthorship 1252907732502393Vaccaro A, Kaplan Dor Y, Nambara K, Pollina EA, Lin C, Greenberg ME, Rogulja DCellSleep Loss Can Cause Death through Accumulation of Reactive Oxygen Species in the Gut. Cell. 2020 06 11; 181(6):1307-1328.e15.Cell2020-06-04T00:00:002020Sleep Loss Can Cause Death through Accumulation of Reactive Oxygen Species in the Gut.Authorship 12657301532637152Gu L, Wang L, Chen H, Hong J, Shen Z, Dhall A, Lao T, Liu C, Wang Z, Xu Y, Tang HW, Chakraborty D, Chen J, Liu Z, Rogulja D, Perrimon N, Wu H, Shi YCell discoveryCG14906 (mettl4) mediates m6A methylation of U2 snRNA in Drosophila. Cell Discov. 2020; 6:44.Cell Discov2020-06-30T00:00:002020CG14906 (mettl4) mediates m6A methylation of U2 snRNA in Drosophila.true1Associate Professor of NeurobiologyAssociate Professor of NeurobiologyAuthorship 1342202333762336Song BJ, Sharp SJ, Rogulja DScience advancesDaily rewiring of a neural circuit generates a predictive model of environmental light. Sci Adv. 2021 03; 7(13).Sci Adv2021-03-24T00:00:002021Daily rewiring of a neural circuit generates a predictive model of environmental light.Authorship 1364987434134981Zhang SX, Glantz EH, Miner LE, Rogulja D, Crickmore MAScience advancesHormonal control of motivational circuitry orchestrates the transition to sexuality in Drosophila. Sci Adv. 2021 Jun; 7(25).Sci Adv2021-06-16T00:00:002021Hormonal control of motivational circuitry orchestrates the transition to sexuality in Drosophila.2025-06-30ROGULJA, DRAGANA2021-07-09Understanding the link between sleep deprivation and oxidative stressR01GM138872Principal Investigatortrue1Associate Professor of Medicine, Part-timeAssociate Professor of Medicine, Part-timeAuthorship 1533363736958331Titos I, Juginovic A, Vaccaro A, Nambara K, Gorelik P, Mazor O, Rogulja DCellA gut-secreted peptide suppresses arousability from sleep. Cell. 2023 03 30; 186(7):1382-1397.e21.Cell2023-03-22T00:00:002023A gut-secreted peptide suppresses arousability from sleep.Authorship 15619377Authorship 15707663037224457Raizen DM, Mullington J, Anaclet C, Clarke G, Critchley H, Dantzer R, Davis R, Drew KL, Fessel J, Fuller PM, Gibson EM, Harrington M, Ian Lipkin W, Klerman EB, Klimas N, Komaroff AL, Koroshetz W, Krupp L, Kuppuswamy A, Lasselin J, Lewis LD, Magistretti PJ, Matos HY, Miaskowski C, Miller AH, Nath A, Nedergaard M, Opp MR, Ritchie MD, Rogulja D, Rolls A, Salamone JD, Saper C, Whittemore V, Wylie G, Younger J, Zee PC, Craig Heller HSleepBeyond the symptom: the biology of fatigue. Sleep. 2023 09 08; 46(9).Sleep2023-09-08T00:00:002023Beyond the symptom: the biology of fatigue.37172567Titos I, Juginovic A, Vaccaro A, Nambara K, Gorelik P, Mazor O, Rogulja DCellA gut-secreted peptide suppresses arousability from sleep. Cell. 2023 May 11; 186(10):2273-2274.Cell2023-05-11T00:00:002023A gut-secreted peptide suppresses arousability from sleep.Authorship 1583947437530645Zhang SX, Glantz EH, Miner LE, Rogulja D, Crickmore MAEMBO reportsWhere does mating drive come from? EMBO Rep. 2023 Oct 09; 24(10):e57771.EMBO Rep2023-08-02T00:00:002023Where does mating drive come from?true1Research Fellow in NeurobiologyResearch Fellow in Neurobiologytrue1Research Fellow in NeurobiologyResearch Fellow in Neurobiologytrue1Professor of GeneticsProfessor of Geneticstrue1Research Fellow in NeurobiologyResearch Fellow in Neurobiologytrue1Instructor in NeurobiologyInstructor in Neurobiologytrue1Frank Baldino, Jr., Ph.D. Professor of Sleep MedicineFrank Baldino, Jr., Ph.D. Professor of Sleep Medicinetrue1Peter C. Farrell Professor of Sleep MedicinePeter C. Farrell Professor of Sleep Medicinetrue1Nathan Marsh Pusey Professor of NeurobiologyNathan Marsh Pusey Professor of NeurobiologyAuthorship 639695YK156YosefKaplan DorYosef Kaplan Dor, Ph.D.121223Kaplan Dor, YosefResearch Fellow in NeurobiologyAuthorship 1665641Authorship 3557041Authorship 357064Authorship 809386626096977Afonso DJ, Liu D, Machado DR, Pan H, Jepson JE, Rogulja D, Koh KCurrent biology : CBTARANIS Functions with Cyclin A and Cdk1 in a Novel Arousal Center to Control Sleep in Drosophila. Curr Biol. 2015 Jun 29; 25(13):1717-26.Curr Biol2015-06-18T00:00:002015TARANIS Functions with Cyclin A and Cdk1 in a Novel Arousal Center to Control Sleep in Drosophila.Authorship 874850327046814Titos I, Crickmore MA, Rogulja DCurrent biology : CBNeuroscience: Suppressing One Drive for a Chance to Satisfy Another. Curr Biol. 2016 Apr 04; 26(7):R282-3.Curr Biol2016-04-04T00:00:002016Neuroscience: Suppressing One Drive for a Chance to Satisfy Another.AV172AlexandraSantiagoAlexandra Santiago, Ph.D.148508Santiago, AlexandraResearch Fellow in Neurobiology1Associate Professor6Fellow or Post Doc0Full Professor4Instructor5Other FacultyAuthorship 891927227292538Zhang SX, Rogulja D, Crickmore MANeuronDopaminergic Circuitry Underlying Mating Drive. Neuron. 2016 07 06; 91(1):168-81.Neuron2016-06-09T00:00:002016Dopaminergic Circuitry Underlying Mating Drive.Authorship 5106151Authorship 964957327115680Titos I, Crickmore MA, Rogulja DCurrent biology : CBNeuroscience: Suppressing One Drive for a Chance to Satisfy Another. Curr Biol. 2016 Apr 25; 26(8):1126.Curr Biol2016-04-25T00:00:002016Neuroscience: Suppressing One Drive for a Chance to Satisfy Another.16269336Rogulja D, Irvine KDCellRegulation of cell proliferation by a morphogen gradient. Cell. 2005 Nov 04; 123(3):449-61.Cell2005-11-04T00:00:002005Regulation of cell proliferation by a morphogen gradient.10906130Naryshkina T, Rogulja D, Golub L, Severinov KThe Journal of biological chemistryInter- and intrasubunit interactions during the formation of RNA polymerase assembly intermediate. J Biol Chem. 2000 Oct 06; 275(40):31183-90.J Biol Chem2000-10-06T00:00:002000Inter- and intrasubunit interactions during the formation of RNA polymerase assembly intermediate.11823642Kuznedelov K, Minakhin L, Niedziela-Majka A, Dove SL, Rogulja D, Nickels BE, Hochschild A, Heyduk T, Severinov KScience (New York, N.Y.)A role for interaction of the RNA polymerase flap domain with the sigma subunit in promoter recognition. Science. 2002 Feb 01; 295(5556):855-7.Science2002-02-01T00:00:002002A role for interaction of the RNA polymerase flap domain with the sigma subunit in promoter recognition.220 Longwood AveHarvard Medical SchoolNeurobiology, Goldenson Bldg220 Longwood AveBoston02115MAAuthorship 1029795229195079Song BJ, Rogulja DCellSnapShot: Circadian Clock. Cell. 2017 Nov 30; 171(6):1468-1468.e1.Cell2017-11-30T00:00:002017SnapShot: Circadian Clock.