Harvard Catalyst Profiles

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Camille Elise Powe, M.D.

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Mentoring
Available: 02/01/23, Expires: 02/01/27

Students can work on projects related to glucose, insulin, and related aspects of metabolic physiology in studies of pregnant individuals at Massachusetts General Hospital. The PI has 3 cohorts which have or are currently profiling pregnant individuals using oral glucose tolerance testing and/or continuous glucose monitoring. Proteomic and/or genomic data is available in some cases. Students can investigate relationships between participant characteristics and behaviors and aspects of glycemic physiology during pregnancy. Students can also examine associations between glucose and insulin physiology and pregnancy outcomes. Students interested in omics approaches can apply them to the study of glycemia in pregnancy and gestational diabetes.

MGH Maternal Health Cohort [login at prompt]
Available: 01/01/00, Expires: 02/01/29

We have assembled a large electronic health record-based cohort at Massachusetts General Hospital which contains clinical data from over 50,000 pregnancies cared for at our hospital. Students can conduct epidemiologic studies of pregnancy outcomes or of associations between pregnancy exposures (for example gestational diabetes, preeclampsia, and preterm birth) and long-term chronic disease risk.

Hemoglobin A1c in pregnancy [login at prompt]
Available: 01/01/00, Expires: 06/01/27

Hemoglobin A1c is commonly used outside of pregnancy to assess glycemia and diagnose diabetes. However, in pregnancy, changes in red blood cell kinetics affect the relationship between blood glucose levels and hemoglobin A1c. We are researching the relationship between hemoglobin A1c and glucose levels (as measured by continuous glucose monitoring) in pregnancy and trying to make testing for and monitoring diabetes easier for pregnant individuals. Students can work on patient-oriented research projects related to hemoglobin A1c. Depending on interest, activities could include data collection (including interacting with participants and placing continuous glucose monitors) and/or data analysis.


Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K26DK138346 (POWE, CAMILLE ELISE) Sep 1, 2023 - Aug 31, 2028
    NIH
    Mentoring Underrepresented Researchers in Diabetes and Pregnancy Investigation
    Role: Principal Investigator
  2. R01HD104756 (POWE, CAMILLE ELISE) Jun 15, 2022 - May 31, 2027
    NIH
    Glycemic Observation Using A1C for Gestational Diabetes Diagnosis
    Role: Multiple Principal Investigator
  3. U01DK123795 (POWE, CAMILLE ELISE) Sep 20, 2019 - Jul 31, 2025
    NIH
    Measuring Early Pregnancy Glycemia and Its Impact on Adverse Outcomes
    Role: Principal Investigator
  4. K23DK113218 (POWE, CAMILLE ELISE) Jul 1, 2017 - May 31, 2022
    NIH
    Elucidating Determinants of Gestational Beta-Cell Adaptation and Failure
    Role: Principal Investigator
  5. 74256 (POWE, CAMILLE ELISE) Jul 1, 2017 - Jun 30, 2021
    Robert Wood Johnson Foundation Harold Amos Medical Faculty Development Program
    Toward Personalized Prevention and Therapy for Gestational Diabetes Mellitus
    Role: Principal Investigator

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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.