DLB5DeborahBlackerDeborah Lynne Blacker, M.D., Sc.D.42.37730000000000-71.0525000000000081503Blacker, DeborahLynne617/726-5571Professor of Psychiatrycatalyst:eCommonsLogineCommons Loginprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:address2address line 2vivo:address3address line 3vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:middleNamemiddle name or initialvivo:personInPositionpositionsvivo:phoneNumberphonePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofvivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson11099823Guénette SY, Bertram L, Crystal A, Bakondi B, Hyman BT, Rebeck GW, Tanzi RE, Blacker DNeuroscience lettersEvidence against association of the FE65 gene (APBB1) intron 13 polymorphism in Alzheimer's patients. Neurosci Lett. 2000 Dec 15; 296(1):17-20.Neurosci Lett2000-12-15T00:00:002000Evidence against association of the FE65 gene (APBB1) intron 13 polymorphism in Alzheimer's patients.14716720Lange C, Blacker D, Laird NMStatistics in medicineFamily-based association tests for survival and times-to-onset analysis. Stat Med. 2004 Jan 30; 23(2):179-89.Stat Med2004-01-30T00:00:002004Family-based association tests for survival and times-to-onset analysis.14745076Bertram L, Menon R, Mullin K, Parkinson M, Bradley ML, Blacker D, Tanzi RENeurologyPEN2 is not a genetic risk factor for Alzheimer's disease in a large family sample. Neurology. 2004 Jan 27; 62(2):304-6.Neurology2004-01-27T00:00:002004PEN2 is not a genetic risk factor for Alzheimer's disease in a large family sample.19233293Jovicich J, Czanner S, Han X, Salat D, van der Kouwe A, Quinn B, Pacheco J, Albert M, Killiany R, Blacker D, Maguire P, Rosas D, Makris N, Gollub R, Dale A, Dickerson BC, Fischl BNeuroImageMRI-derived measurements of human subcortical, ventricular and intracranial brain volumes: Reliability effects of scan sessions, acquisition sequences, data analyses, scanner upgrade, scanner vendors and field strengths. Neuroimage. 2009 May 15; 46(1):177-92.Neuroimage2009-02-20T00:00:002009MRI-derived measurements of human subcortical, ventricular and intracranial brain volumes: Reliability effects of scan sessions, acquisition sequences, data analyses, scanner upgrade, scanner vendors and field strengths.19262963Zhu CW, Leibman C, Townsend R, McLaughlin T, Scarmeas N, Albert M, Brandt J, Blacker D, Sano M, Stern YThe journal of nutrition, health & agingBridging from clinical endpoints to estimates of treatment value for external decision makers. J Nutr Health Aging. 2009 Mar; 13(3):256-9.J Nutr Health Aging2009-03-01T00:00:002009Bridging from clinical endpoints to estimates of treatment value for external decision makers.16374805Jiang H, Harrington D, Raby BA, Bertram L, Blacker D, Weiss ST, Lange CGenetic epidemiologyFamily-based association test for time-to-onset data with time-dependent differences between the hazard functions. Genet Epidemiol. 2006 Feb; 30(2):124-32.Genet Epidemiol2006-02-01T00:00:002006Family-based association test for time-to-onset data with time-dependent differences between the hazard functions.17030662Stavitsky K, Brickman AM, Scarmeas N, Torgan RL, Tang MX, Albert M, Brandt J, Blacker D, Stern YArchives of neurologyThe progression of cognition, psychiatric symptoms, and functional abilities in dementia with Lewy bodies and Alzheimer disease. Arch Neurol. 2006 Oct; 63(10):1450-6.Arch Neurol2006-10-01T00:00:002006The progression of cognition, psychiatric symptoms, and functional abilities in dementia with Lewy bodies and Alzheimer disease.17038080Zhu CW, Scarmeas N, Torgan R, Albert M, Brandt J, Blacker D, Sano M, Stern YJournal of the American Geriatrics SocietyClinical characteristics and longitudinal changes of informal cost of Alzheimer's disease in the community. J Am Geriatr Soc. 2006 Oct; 54(10):1596-602.J Am Geriatr Soc2006-10-01T00:00:002006Clinical characteristics and longitudinal changes of informal cost of Alzheimer's disease in the community.18662215Zhu CW, Leibman C, McLaughlin T, Scarmeas N, Albert M, Brandt J, Blacker D, Sano M, Stern YJournal of the American Geriatrics SocietyThe effects of patient function and dependence on costs of care in Alzheimer's disease. J Am Geriatr Soc. 2008 Aug; 56(8):1497-503.J Am Geriatr Soc2008-07-24T00:00:002008The effects of patient function and dependence on costs of care in Alzheimer's disease.19070563Bertram L, Schjeide BM, Hooli B, Mullin K, Hiltunen M, Soininen H, Ingelsson M, Lannfelt L, Blacker D, Tanzi RECellNo association between CALHM1 and Alzheimer's disease risk. Cell. 2008 Dec 12; 135(6):993-4; author reply 994-6.Cell2008-12-12T00:00:002008No association between CALHM1 and Alzheimer's disease risk.Authorship 101309714975164McQueen MB, Bertram L, Rimm EB, Blacker D, Santangelo SLBMC geneticsA QTL genome scan of the metabolic syndrome and its component traits. BMC Genet. 2003 Dec 31; 4 Suppl 1:S96.BMC Genet2003-12-31T00:00:002003A QTL genome scan of the metabolic syndrome and its component traits.16087905Dickerson BC, Salat DH, Greve DN, Chua EF, Rand-Giovannetti E, Rentz DM, Bertram L, Mullin K, Tanzi RE, Blacker D, Albert MS, Sperling RANeurologyIncreased hippocampal activation in mild cognitive impairment compared to normal aging and AD. Neurology. 2005 Aug 09; 65(3):404-11.Neurology2005-08-09T00:00:002005Increased hippocampal activation in mild cognitive impairment compared to normal aging and AD.18830724Schjeide BM, McQueen MB, Mullin K, DiVito J, Hogan MF, Parkinson M, Hooli B, Lange C, Blacker D, Tanzi RE, Bertram LNeurogeneticsAssessment of Alzheimer's disease case-control associations using family-based methods. Neurogenetics. 2009 Feb; 10(1):19-25.Neurogenetics2008-10-02T00:00:002008Assessment of Alzheimer's disease case-control associations using family-based methods.19571734Pihlajamäki M, O' Keefe K, Bertram L, Tanzi RE, Dickerson BC, Blacker D, Albert MS, Sperling RAAlzheimer disease and associated disordersEvidence of altered posteromedial cortical FMRI activity in subjects at risk for Alzheimer disease. Alzheimer Dis Assoc Disord. 2010 Jan-Mar; 24(1):28-36.Alzheimer Dis Assoc Disord2010-01-01T00:00:002010Evidence of altered posteromedial cortical FMRI activity in subjects at risk for Alzheimer disease.Authorship 1047842Authorship 1065524629765027Lin YF, Chen CY, Öngür D, Betensky R, Smoller JW, Blacker D, Hall MHTranslational psychiatryPolygenic pleiotropy and potential causal relationships between educational attainment, neurobiological profile, and positive psychotic symptoms. Transl Psychiatry. 2018 05 16; 8(1):97.Transl Psychiatry2018-05-16T00:00:002018Polygenic pleiotropy and potential causal relationships between educational attainment, neurobiological profile, and positive psychotic symptoms.16930382Monuteaux MC, Blacker D, Biederman J, Fitzmaurice G, Buka SLJournal of child psychology and psychiatry, and allied disciplinesMaternal smoking during pregnancy and offspring overt and covert conduct problems: a longitudinal study. J Child Psychol Psychiatry. 2006 Sep; 47(9):883-90.J Child Psychol Psychiatry2006-09-01T00:00:002006Maternal smoking during pregnancy and offspring overt and covert conduct problems: a longitudinal study.20697030Jun G, Naj AC, Beecham GW, Wang LS, Buros J, Gallins PJ, Buxbaum JD, Ertekin-Taner N, Fallin MD, Friedland R, Inzelberg R, Kramer P, Rogaeva E, St George-Hyslop P, Cantwell LB, Dombroski BA, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Lunetta KL, Martin ER, Montine TJ, Goate AM, Blacker D, Tsuang DW, Beekly D, Cupples LA, Hakonarson H, Kukull W, Foroud TM, Haines J, Mayeux R, Farrer LA, Pericak-Vance MA, Schellenberg GDArchives of neurologyMeta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes. Arch Neurol. 2010 Dec; 67(12):1473-84.Arch Neurol2010-08-09T00:00:002010Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes.21161449Pihlajamäki M, O'Keefe K, O'Brien J, Blacker D, Sperling RABrain imaging and behaviorFailure of repetition suppression and memory encoding in aging and Alzheimer's disease. Brain Imaging Behav. 2011 Mar; 5(1):36-44.Brain Imaging Behav2011-03-01T00:00:002011Failure of repetition suppression and memory encoding in aging and Alzheimer's disease.21403019Okereke OI, Copeland M, Hyman BT, Wanggaard T, Albert MS, Blacker DArchives of neurologyThe Structured Interview & Scoring Tool-Massachusetts Alzheimer's Disease Research Center (SIST-M): development, reliability, and cross-sectional validation of a brief structured clinical dementia rating interview. Arch Neurol. 2011 Mar; 68(3):343-50.Arch Neurol2011-03-01T00:00:002011The Structured Interview & Scoring Tool-Massachusetts Alzheimer's Disease Research Center (SIST-M): development, reliability, and cross-sectional validation of a brief structured clinical dementia rating interview.Authorship 1069459129847611Blacker D, Weuve JJAMA psychiatryBrain Exercise and Brain Outcomes: Does Cognitive Activity Really Work to Maintain Your Brain? JAMA Psychiatry. 2018 07 01; 75(7):703-704.JAMA Psychiatry2018-07-01T00:00:002018Brain Exercise and Brain Outcomes: Does Cognitive Activity Really Work to Maintain Your Brain?23143602Whitcomb DC, LaRusch J, Krasinskas AM, Klei L, Smith JP, Brand RE, Neoptolemos JP, Lerch MM, Tector M, Sandhu BS, Guda NM, Orlichenko L, Alkaade S, Amann ST, Anderson MA, Baillie J, Banks PA, Conwell D, Coté GA, Cotton PB, DiSario J, Farrer LA, Forsmark CE, Johnstone M, Gardner TB, Gelrud A, Greenhalf W, Haines JL, Hartman DJ, Hawes RA, Lawrence C, Lewis M, Mayerle J, Mayeux R, Melhem NM, Money ME, Muniraj T, Papachristou GI, Pericak-Vance MA, Romagnuolo J, Schellenberg GD, Sherman S, Simon P, Singh VP, Slivka A, Stolz D, Sutton R, Weiss FU, Wilcox CM, Zarnescu NO, Wisniewski SR, O'Connell MR, Kienholz ML, Roeder K, Barmada MM, Yadav D, Devlin BNature geneticsCommon genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. Nat Genet. 2012 Dec; 44(12):1349-54.Nat Genet2012-11-11T00:00:002012Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.Authorship 1194002216272261Bertram L, Parkinson M, McQueen MB, Mullin K, Hsiao M, Menon R, Moscarillo TJ, Blacker D, Tanzi REJournal of medical geneticsFurther evidence for LBP-1c/CP2/LSF association in Alzheimer's disease families. J Med Genet. 2005 Nov; 42(11):857-62.J Med Genet2005-11-01T00:00:002005Further evidence for LBP-1c/CP2/LSF association in Alzheimer's disease families.17562935Blacker D, Lee H, Muzikansky A, Martin EC, Tanzi R, McArdle JJ, Moss M, Albert MArchives of neurologyNeuropsychological measures in normal individuals that predict subsequent cognitive decline. Arch Neurol. 2007 Jun; 64(6):862-71.Arch Neurol2007-06-01T00:00:002007Neuropsychological measures in normal individuals that predict subsequent cognitive decline.17846109Miller SL, Fenstermacher E, Bates J, Blacker D, Sperling RA, Dickerson BCJournal of neurology, neurosurgery, and psychiatryHippocampal activation in adults with mild cognitive impairment predicts subsequent cognitive decline. J Neurol Neurosurg Psychiatry. 2008 Jun; 79(6):630-5.J Neurol Neurosurg Psychiatry2007-09-10T00:00:002007Hippocampal activation in adults with mild cognitive impairment predicts subsequent cognitive decline.18071039Scarmeas N, Brandt J, Blacker D, Albert M, Hadjigeorgiou G, Dubois B, Devanand D, Honig L, Stern YArchives of neurologyDisruptive behavior as a predictor in Alzheimer disease. Arch Neurol. 2007 Dec; 64(12):1755-61.Arch Neurol2007-12-01T00:00:002007Disruptive behavior as a predictor in Alzheimer disease.Authorship 107444518195145Smith EE, Egorova S, Blacker D, Killiany RJ, Muzikansky A, Dickerson BC, Tanzi RE, Albert MS, Greenberg SM, Guttmann CRArchives of neurologyMagnetic resonance imaging white matter hyperintensities and brain volume in the prediction of mild cognitive impairment and dementia. Arch Neurol. 2008 Jan; 65(1):94-100.Arch Neurol2008-01-01T00:00:002008Magnetic resonance imaging white matter hyperintensities and brain volume in the prediction of mild cognitive impairment and dementia.8135302Blacker D, Lavori PW, Faraone SV, Tsuang MTAmerican journal of medical geneticsUnipolar relatives in bipolar pedigrees: a search for indicators of underlying bipolarity. Am J Med Genet. 1993 Dec 15; 48(4):192-9.Am J Med Genet1993-12-15T00:00:001993Unipolar relatives in bipolar pedigrees: a search for indicators of underlying bipolarity.18292383Holland CM, Smith EE, Csapo I, Gurol ME, Brylka DA, Killiany RJ, Blacker D, Albert MS, Guttmann CR, Greenberg SMStrokeSpatial distribution of white-matter hyperintensities in Alzheimer disease, cerebral amyloid angiopathy, and healthy aging. Stroke. 2008 Apr; 39(4):1127-33.Stroke2008-02-21T00:00:002008Spatial distribution of white-matter hyperintensities in Alzheimer disease, cerebral amyloid angiopathy, and healthy aging.19667221Scarmeas N, Honig LS, Choi H, Cantero J, Brandt J, Blacker D, Albert M, Amatniek JC, Marder K, Bell K, Hauser WA, Stern YArchives of neurologySeizures in Alzheimer disease: who, when, and how common? Arch Neurol. 2009 Aug; 66(8):992-7.Arch Neurol2009-08-01T00:00:002009Seizures in Alzheimer disease: who, when, and how common?22451159Koyama A, Okereke OI, Yang T, Blacker D, Selkoe DJ, Grodstein FArchives of neurologyPlasma amyloid-ß as a predictor of dementia and cognitive decline: a systematic review and meta-analysis. Arch Neurol. 2012 Jul; 69(7):824-31.Arch Neurol2012-07-01T00:00:002012Plasma amyloid-ß as a predictor of dementia and cognitive decline: a systematic review and meta-analysis.22982688Koyama A, O'Brien J, Weuve J, Blacker D, Metti AL, Yaffe KThe journals of gerontology. Series A, Biological sciences and medical sciencesThe role of peripheral inflammatory markers in dementia and Alzheimer's disease: a meta-analysis. J Gerontol A Biol Sci Med Sci. 2013 Apr; 68(4):433-40.J Gerontol A Biol Sci Med Sci2012-09-14T00:00:002012The role of peripheral inflammatory markers in dementia and Alzheimer's disease: a meta-analysis.18625856Steinerman JR, Irizarry M, Scarmeas N, Raju S, Brandt J, Albert M, Blacker D, Hyman B, Stern YArchives of neurologyDistinct pools of beta-amyloid in Alzheimer disease-affected brain: a clinicopathologic study. Arch Neurol. 2008 Jul; 65(7):906-12.Arch Neurol2008-07-01T00:00:002008Distinct pools of beta-amyloid in Alzheimer disease-affected brain: a clinicopathologic study.18632739Dickerson BC, Bakkour A, Salat DH, Feczko E, Pacheco J, Greve DN, Grodstein F, Wright CI, Blacker D, Rosas HD, Sperling RA, Atri A, Growdon JH, Hyman BT, Morris JC, Fischl B, Buckner RLCerebral cortex (New York, N.Y. : 1991)The cortical signature of Alzheimer's disease: regionally specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloid-positive individuals. Cereb Cortex. 2009 Mar; 19(3):497-510.Cereb Cortex2008-07-16T00:00:002008The cortical signature of Alzheimer's disease: regionally specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloid-positive individuals.Authorship 1093594830240575Lin YF, Smith AV, Aspelund T, Betensky RA, Smoller JW, Gudnason V, Launer LJ, Blacker DAlzheimer's & dementia : the journal of the Alzheimer's AssociationGenetic overlap between vascular pathologies and Alzheimer's dementia and potential causal mechanisms. Alzheimers Dement. 2019 01; 15(1):65-75.Alzheimers Dement2018-09-19T00:00:002018Genetic overlap between vascular pathologies and Alzheimer's dementia and potential causal mechanisms.15236399Dickerson BC, Salat DH, Bates JF, Atiya M, Killiany RJ, Greve DN, Dale AM, Stern CE, Blacker D, Albert MS, Sperling RAAnnals of neurologyMedial temporal lobe function and structure in mild cognitive impairment. Ann Neurol. 2004 Jul; 56(1):27-35.Ann Neurol2004-07-01T00:00:002004Medial temporal lobe function and structure in mild cognitive impairment.21986342Okereke OI, Pantoja-Galicia N, Copeland M, Hyman BT, Wanggaard T, Albert MS, Betensky RA, Blacker DAlzheimer disease and associated disordersThe SIST-M: predictive validity of a brief structured clinical dementia rating interview. Alzheimer Dis Assoc Disord. 2012 Jul-Sep; 26(3):225-31.Alzheimer Dis Assoc Disord2012-07-01T00:00:002012The SIST-M: predictive validity of a brief structured clinical dementia rating interview.11043085Blacker DPostgraduate medicineNew insights into genetic aspects of Alzheimer's disease. Does genetic information make a difference in clinical practice? Postgrad Med. 2000 Oct; 108(5):119-22, 125-6, 129.Postgrad Med2000-10-01T00:00:002000New insights into genetic aspects of Alzheimer's disease. Does genetic information make a difference in clinical practice?7986174Blacker D, Albert MS, Bassett SS, Go RC, Harrell LE, Folstein MFArchives of neurologyReliability and validity of NINCDS-ADRDA criteria for Alzheimer's disease. The National Institute of Mental Health Genetics Initiative. Arch Neurol. 1994 Dec; 51(12):1198-204.Arch Neurol1994-12-01T00:00:001994Reliability and validity of NINCDS-ADRDA criteria for Alzheimer's disease. The National Institute of Mental Health Genetics Initiative.11125142Bertram L, Blacker D, Mullin K, Keeney D, Jones J, Basu S, Yhu S, McInnis MG, Go RC, Vekrellis K, Selkoe DJ, Saunders AJ, Tanzi REScience (New York, N.Y.)Evidence for genetic linkage of Alzheimer's disease to chromosome 10q. Science. 2000 Dec 22; 290(5500):2302-3.Science2000-12-22T00:00:002000Evidence for genetic linkage of Alzheimer's disease to chromosome 10q.12851634Bertram L, Saunders AJ, Mullin K, Sampson A, Moscarillo TJ, Basset SS, Go RC, Blacker D, Tanzi REMolecular psychiatryNo association between marker D10S1423 and Alzheimer's disease. Mol Psychiatry. 2003 Jun; 8(6):571-3.Mol Psychiatry2003-06-01T00:00:002003No association between marker D10S1423 and Alzheimer's disease.16530430Desikan RS, Ségonne F, Fischl B, Quinn BT, Dickerson BC, Blacker D, Buckner RL, Dale AM, Maguire RP, Hyman BT, Albert MS, Killiany RJNeuroImageAn automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. Neuroimage. 2006 Jul 01; 31(3):968-80.Neuroimage2006-03-10T00:00:002006An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest.15060104Bertram L, Parkinson M, Mullin K, Menon R, Blacker D, Tanzi REJournal of medical geneticsNo association between a previously reported OLR1 3' UTR polymorphism and Alzheimer's disease in a large family sample. J Med Genet. 2004 Apr; 41(4):286-8.J Med Genet2004-04-01T00:00:002004No association between a previously reported OLR1 3' UTR polymorphism and Alzheimer's disease in a large family sample.17942325Dickerson BC, Fenstermacher E, Salat DH, Wolk DA, Maguire RP, Desikan R, Pacheco J, Quinn BT, Van der Kouwe A, Greve DN, Blacker D, Albert MS, Killiany RJ, Fischl BNeuroImageDetection of cortical thickness correlates of cognitive performance: Reliability across MRI scan sessions, scanners, and field strengths. Neuroimage. 2008 Jan 01; 39(1):10-8.Neuroimage2007-09-05T00:00:002007Detection of cortical thickness correlates of cognitive performance: Reliability across MRI scan sessions, scanners, and field strengths.18189239Dickson MR, Li J, Wiener HW, Perry RT, Blacker D, Bassett SS, Go RCAmerican journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric GeneticsA genomic scan for age at onset of Alzheimer's disease in 437 families from the NIMH Genetic Initiative. Am J Med Genet B Neuropsychiatr Genet. 2008 Sep 05; 147B(6):784-92.Am J Med Genet B Neuropsychiatr Genet2008-09-05T00:00:002008A genomic scan for age at onset of Alzheimer's disease in 437 families from the NIMH Genetic Initiative.18779424Brickman AM, Honig LS, Scarmeas N, Tatarina O, Sanders L, Albert MS, Brandt J, Blacker D, Stern YArchives of neurologyMeasuring cerebral atrophy and white matter hyperintensity burden to predict the rate of cognitive decline in Alzheimer disease. Arch Neurol. 2008 Sep; 65(9):1202-8.Arch Neurol2008-09-01T00:00:002008Measuring cerebral atrophy and white matter hyperintensity burden to predict the rate of cognitive decline in Alzheimer disease.18976728Bertram L, Lange C, Mullin K, Parkinson M, Hsiao M, Hogan MF, Schjeide BM, Hooli B, Divito J, Ionita I, Jiang H, Laird N, Moscarillo T, Ohlsen KL, Elliott K, Wang X, Hu-Lince D, Ryder M, Murphy A, Wagner SL, Blacker D, Becker KD, Tanzi REAmerican journal of human geneticsGenome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE. Am J Hum Genet. 2008 Nov; 83(5):623-32.Am J Hum Genet2008-10-30T00:00:002008Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE.22244033Reiman EM, McKhann GM, Albert MS, Sperling RA, Petersen RC, Blacker DThe Journal of clinical psychiatryClinical impact of updated diagnostic and research criteria for Alzheimer's disease. J Clin Psychiatry. 2011 Dec; 72(12):e37.J Clin Psychiatry2011-12-01T00:00:002011Clinical impact of updated diagnostic and research criteria for Alzheimer's disease.Authorship 1131228330762723Moura LMVR, Smith JR, Blacker D, Vogeli C, Schwamm LH, Cole AJ, Hernandez-Diaz S, Hsu JMedical careEpilepsy Among Elderly Medicare Beneficiaries: A Validated Approach to Identify Prevalent and Incident Epilepsy. Med Care. 2019 04; 57(4):318-324.Med Care2019-04-01T00:00:002019Epilepsy Among Elderly Medicare Beneficiaries: A Validated Approach to Identify Prevalent and Incident Epilepsy.Authorship 113901091Authorship 1139431330780120Moura LMVR, Smith JR, Blacker D, Vogeli C, Schwamm LH, Hsu JEpilepsy researchMedicare claims can identify post-stroke epilepsy. Epilepsy Res. 2019 03; 151:40-47.Epilepsy Res2019-02-08T00:00:002019Medicare claims can identify post-stroke epilepsy.30820047Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujic-Comic H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Andre Uitterlinden AG, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, et alNature geneticsGenetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aß, tau, immunity and lipid processing. Nat Genet. 2019 03; 51(3):414-430.Nat Genet2019-02-28T00:00:002019Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aß, tau, immunity and lipid processing.D003072Disorders116940260.348855Cognition DisordersD000544Disorders127179750.222139Alzheimer DiseaseD003704Disorders76424880.357651DementiaD053327Chemicals & Drugs2376690.712591Apolipoprotein E4Authorship 11449647Authorship 1145067430958913Gillis JC, Chang SC, Wang W, Simon NM, Normand SL, Rosner BA, Blacker D, DeVivo I, Okereke OIDepression and anxietyThe relation of telomere length at midlife to subsequent 20-year depression trajectories among women. Depress Anxiety. 2019 06; 36(6):565-575.Depress Anxiety2019-04-08T00:00:002019The relation of telomere length at midlife to subsequent 20-year depression trajectories among women.30991799Das AS, Regenhardt RW, Vernooij MW, Blacker D, Charidimou A, Viswanathan AJournal of strokeAsymptomatic Cerebral Small Vessel Disease: Insights from Population-Based Studies. J Stroke. 2019 May; 21(2):121-138.J Stroke2019-04-17T00:00:002019Asymptomatic Cerebral Small Vessel Disease: Insights from Population-Based Studies.D001057Chemicals & Drugs51714370.63785Apolipoproteins EEpidemiologyNeurologyNutritionPsychiatryRadiologyBrigham and Women's HospitalHarvard T.H. Chan School of Public HealthMassachusetts General HospitalCRS1CarlSchwartzCarl R.E. Schwartz, M.D.42.37730000000000-71.0525000000000019178Schwartz, CarlAssistant Professor of PsychiatryMLB1MariaButtolphMaria Lynn Buttolph, M.D., Ph.D.42.37730000000000-71.052500000000007867Buttolph, MariaInstructor in PsychiatryOIO1OliviaOkerekeOlivia Ifeoma Okereke, M.D.42.33669100000000-71.1020890000000069468Okereke, OliviaAssociate Professor of PsychiatryDJH2DaphneHoltDaphne Jane Holt, M.D., Ph.D.42.37730000000000-71.0525000000000051423Holt, DaphneAssociate Professor of PsychiatryRLG2RandyGollubRandy Lyanne Gollub, M.D., Ph.D.42.37730000000000-71.0525000000000075846Gollub, RandyProfessor of PsychiatryRAS4ReisaSperlingReisa Anne Sperling, M.D.42.33710500000000-71.1023170000000020632Sperling, ReisaProfessor of NeurologyBTH2BradleyHymanBradley Theodore Hyman, M.D., Ph.D.42.37904200000000-71.051481000000004393Hyman, BradleyJohn B. Penney, Jr. Professor of NeurologyRET2RudolphTanziRudolph Emile Tanzi, Ph.D.42.37904200000000-71.0514810000000066118Tanzi, RudolphJoseph P. and Rose F. Kennedy Professor of Child Neurology and Mental RetardationAV13AnandViswanathanAnand Viswanathan, M.D., Ph.D.42.36126580000000-71.0651591000000024417Viswanathan, AnandAssociate Professor of NeurologyKAJ1KeithJohnsonKeith Alan Johnson, M.D.42.36241700000000-71.0689370000000016670Johnson, KeithProfessor of RadiologyJLR10JoshuaRoffmanJoshua Lawrence Roffman, M.D.42.37730000000000-71.0525000000000050182Roffman, JoshuaAssociate Professor of Psychiatry11237selected publications3.826370.00387634524research areas2.641860.0107471143coauthor of125.5125.169560similar toAuthorship 1231585Authorship 14553413Authorship 1390811Authorship 11795141231397865Gatchel JR, Rabin JS, Buckley RF, Locascio JJ, Quiroz YT, Yang HS, Vannini P, Amariglio RE, Rentz DM, Properzi M, Donovan NJ, Blacker D, Johnson KA, Sperling RA, Marshall GAJAMA network openLongitudinal Association of Depression Symptoms With Cognition and Cortical Amyloid Among Community-Dwelling Older Adults. JAMA Netw Open. 2019 08 02; 2(8):e198964.JAMA Netw Open2019-08-02T00:00:002019Longitudinal Association of Depression Symptoms With Cognition and Cortical Amyloid Among Community-Dwelling Older Adults.Authorship 1333867Authorship 11843899131417202Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujic-Comic H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Uitterlinden AGA, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, et alNature geneticsAuthor Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aß, tau, immunity and lipid processing. Nat Genet. 2019 Sep; 51(9):1423-1424.Nat Genet2019-09-01T00:00:002019Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aß, tau, immunity and lipid processing.true1Instructor in PsychiatryInstructor in Psychiatrytrue1Assistant Professor of PsychiatryAssistant Professor of Psychiatrytrue1Professor of NeurologyProfessor of Neurologytrue1John B. Penney, Jr. Professor of NeurologyJohn B. Penney, Jr. Professor of Neurologytrue1Associate Professor of PsychiatryAssociate Professor of Psychiatrytrue1Joseph P. and Rose F. Kennedy Professor of Child Neurology and Mental RetardationJoseph P. and Rose F. Kennedy Professor of Child Neurology and Mental Retardationtrue1Professor of PsychiatryProfessor of PsychiatryAuthorship 1421555Authorship 1445859Authorship 1209134431771460Ma Y, Song A, Viswanathan A, Blacker D, Vernooij MW, Hofman A, Papatheodorou SStrokeBlood Pressure Variability and Cerebral Small Vessel Disease: A Systematic Review and Meta-Analysis of Population-Based Cohorts. Stroke. 2020 01; 51(1):82-89.Stroke2019-11-27T00:00:002019Blood Pressure Variability and Cerebral Small Vessel Disease: A Systematic Review and Meta-Analysis of Population-Based Cohorts.Authorship 1221575731999169Reeves S, Williams V, Costela FM, Palumbo R, Umoren O, Christopher MM, Blacker D, Woods RLNeuropsychologyNarrative video scene description task discriminates between levels of cognitive impairment in Alzheimer's disease. Neuropsychology. 2020 May; 34(4):437-446.Neuropsychology2020-01-30T00:00:002020Narrative video scene description task discriminates between levels of cognitive impairment in Alzheimer's disease.32144001Wilkins JM, Locascio JJ, Gunther JM, Yap L, Hyman BT, Blacker D, Forester BP, Okereke OIThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric PsychiatryDifferences in Assessment of Everyday Preferences Between People With Cognitive Impairment and Their Care Partners: The Role of Neuropsychiatric Symptoms. Am J Geriatr Psychiatry. 2020 10; 28(10):1070-1078.Am J Geriatr Psychiatry2020-02-06T00:00:002020Differences in Assessment of Everyday Preferences Between People With Cognitive Impairment and Their Care Partners: The Role of Neuropsychiatric Symptoms.Authorship 12314346Authorship 17997510Authorship 1845199Authorship 162532Authorship 1771717Authorship 1799407Authorship 1249314432408975Ma Y, Yilmaz P, Bos D, Blacker D, Viswanathan A, Ikram MA, Hofman A, Vernooij MW, Ikram MKJournal of the American College of CardiologyBlood Pressure Variation and Subclinical Brain Disease. J Am Coll Cardiol. 2020 05 19; 75(19):2387-2399.J Am Coll Cardiol2020-05-19T00:00:002020Blood Pressure Variation and Subclinical Brain Disease.Authorship 1759606Authorship 1262437832611641Wolters FJ, Chibnik LB, Waziry R, Anderson R, Berr C, Beiser A, Bis JC, Blacker D, Bos D, Brayne C, Dartigues JF, Darweesh SKL, Davis-Plourde KL, de Wolf F, Debette S, Dufouil C, Fornage M, Goudsmit J, Grasset L, Gudnason V, Hadjichrysanthou C, Helmer C, Ikram MA, Ikram MK, Joas E, Kern S, Kuller LH, Launer L, Lopez OL, Matthews FE, McRae-McKee K, Meirelles O, Mosley TH, Pase MP, Psaty BM, Satizabal CL, Seshadri S, Skoog I, Stephan BCM, Wetterberg H, Wong MM, Zettergren A, Hofman ANeurologyTwenty-seven-year time trends in dementia incidence in Europe and the United States: The Alzheimer Cohorts Consortium. Neurology. 2020 08 04; 95(5):e519-e531.Neurology2020-07-01T00:00:002020Twenty-seven-year time trends in dementia incidence in Europe and the United States: The Alzheimer Cohorts Consortium.Authorship 1347845TY95Tian-ShinYehTian-Shin Yeh147352Yeh, Tian-ShinVisiting ScientistAuthorship 1292582433009718Moura LMVR, Smith JR, Yan Z, Blacker D, Schwamm LH, Newhouse JP, Hernandez-Diaz S, Hsu JPharmacoepidemiology and drug safetyPatterns of anticonvulsant use and adverse drug events in older adults. Pharmacoepidemiol Drug Saf. 2021 01; 30(1):28-36.Pharmacoepidemiol Drug Saf2020-10-02T00:00:002020Patterns of anticonvulsant use and adverse drug events in older adults.Authorship 1293125533016904Mezlini AM, Magdamo C, Merrill E, Chibnik LB, Blacker DL, Hyman BT, Das SJournal of Alzheimer's disease : JADCharacterizing Clinical and Neuropathological Traits of APOE Haplotypes in African Americans and Europeans. J Alzheimers Dis. 2020; 78(1):467-477.J Alzheimers Dis2020-01-01T00:00:002020Characterizing Clinical and Neuropathological Traits of APOE Haplotypes in African Americans and Europeans.33455605Wilkins JM, Locascio JJ, Gunther JM, Yap L, Gomez-Isla T, Hyman BT, Blacker D, Forester BP, Okereke OIInternational psychogeriatricsPredictors of the importance of everyday preferences for older adults with cognitive impairment. Int Psychogeriatr. 2022 03; 34(3):287-294.Int Psychogeriatr2021-01-18T00:00:002021Predictors of the importance of everyday preferences for older adults with cognitive impairment.Authorship 13226713Authorship 1322974733480172Wilcock D, Jicha G, Blacker D, Albert MS, D'Orazio LM, Elahi FM, Fornage M, Hinman JD, Knoefel J, Kramer J, Kryscio RJ, Lamar M, Moghekar A, Prestopnik J, Ringman JM, Rosenberg G, Sagare A, Satizabal CL, Schneider J, Seshadri S, Sur S, Tracy RP, Yasar S, Williams V, Singh H, Mazina L, Helmer KG, Corriveau RA, Schwab K, Kivisäkk P, Greenberg SMAlzheimer's & dementia : the journal of the Alzheimer's AssociationMarkVCID cerebral small vessel consortium: I. Enrollment, clinical, fluid protocols. Alzheimers Dement. 2021 04; 17(4):704-715.Alzheimers Dement2021-01-21T00:00:002021MarkVCID cerebral small vessel consortium: I. Enrollment, clinical, fluid protocols.Authorship 1326602733516288Floud S, Balkwill A, Sweetland S, Brown A, Reus EM, Hofman A, Blacker D, Kivimaki M, Green J, Peto R, Reeves GK, Beral VThe Lancet. Public healthCognitive and social activities and long-term dementia risk: the prospective UK Million Women Study. Lancet Public Health. 2021 02; 6(2):e116-e123.Lancet Public Health2021-02-01T00:00:002021Cognitive and social activities and long-term dementia risk: the prospective UK Million Women Study.Authorship 2223811Authorship 163008433903194Ma Y, Blacker D, Viswanathan A, van Veluw SJ, Bos D, Vernooij MW, Hyman BT, Tzourio C, Das S, Hofman ANeurologyVisit-to-Visit Blood Pressure Variability, Neuropathology, and Cognitive Decline. Neurology. 2021 06 08; 96(23):e2812-e2823.Neurology2021-04-26T00:00:002021Visit-to-Visit Blood Pressure Variability, Neuropathology, and Cognitive Decline.Authorship 13494482Authorship 1350232833901296Moura LMVR, Festa N, Price M, Volya M, Benson NM, Zafar S, Weiss M, Blacker D, Normand SL, Newhouse JP, Hsu JJournal of the American Geriatrics SocietyIdentifying Medicare beneficiaries with dementia. J Am Geriatr Soc. 2021 08; 69(8):2240-2251.J Am Geriatr Soc2021-04-26T00:00:002021Identifying Medicare beneficiaries with dementia.33908043Nevo D, Blacker D, Larson EB, Haneuse SBiometricsModeling semi-competing risks data as a longitudinal bivariate process. Biometrics. 2022 09; 78(3):922-936.Biometrics2021-05-18T00:00:002021Modeling semi-competing risks data as a longitudinal bivariate process.Authorship 1355490234020447Yeh TS, Blacker D, Ascherio AThe American journal of clinical nutritionTo meat or not to meat? Processed meat and risk of dementia. Am J Clin Nutr. 2021 07 01; 114(1):7-8.Am J Clin Nutr2021-07-01T00:00:002021To meat or not to meat? Processed meat and risk of dementia.Authorship 1363946634126758Jones FJS, Sanches PR, Smith JR, Zafar SF, Hernandez-Diaz S, Blacker D, Hsu J, Schwamm LH, Westover MB, Moura LMVRStrokeAnticonvulsant Primary and Secondary Prophylaxis for Acute Ischemic Stroke Patients: A Decision Analysis. Stroke. 2021 08; 52(9):2782-2791.Stroke2021-06-15T00:00:002021Anticonvulsant Primary and Secondary Prophylaxis for Acute Ischemic Stroke Patients: A Decision Analysis.34293099Yeh TS, Yuan C, Ascherio A, Rosner BA, Blacker D, Willett WCThe American journal of clinical nutritionLong-term dietary protein intake and subjective cognitive decline in US men and women. Am J Clin Nutr. 2022 01 11; 115(1):199-210.Am J Clin Nutr2022-01-11T00:00:002022Long-term dietary protein intake and subjective cognitive decline in US men and women.Authorship 1376967534321362Yeh TS, Yuan C, Ascherio A, Rosner BA, Willett WC, Blacker DNeurologyLong-term Dietary Flavonoid Intake and Subjective Cognitive Decline in US Men and Women. Neurology. 2021 09 07; 97(10):e1041-e1056.Neurology2021-07-28T00:00:002021Long-term Dietary Flavonoid Intake and Subjective Cognitive Decline in US Men and Women.Authorship 13786675Authorship 1379609634309642Jones FJS, Sanches PR, Smith JR, Zafar SF, Blacker D, Hsu J, Schwamm LH, Newhouse JP, Westover MB, Moura LMVRJAMA neurologySeizure Prophylaxis After Spontaneous Intracerebral Hemorrhage. JAMA Neurol. 2021 09 01; 78(9):1128-1136.JAMA Neurol2021-09-01T00:00:002021Seizure Prophylaxis After Spontaneous Intracerebral Hemorrhage.34498322Wilkins JM, Locascio JJ, Gunther JM, Gomez-Isla T, Hyman BT, Blacker D, Forester BP, Okereke OIInternational journal of geriatric psychiatryLongitudinal differences in everyday preferences: Comparisons between people with cognitive impairment and their care partners. Int J Geriatr Psychiatry. 2021 Sep 08; 37(1).Int J Geriatr Psychiatry2021-09-08T00:00:002021Longitudinal differences in everyday preferences: Comparisons between people with cognitive impairment and their care partners.Authorship 13942796Authorship 1398017234569956Lan YT, Blacker D, Yuan C, Chibnik LB, Hofman A, Ma YJournal of Alzheimer's disease : JADLongitudinal Body Weight Change, Visit-To-Visit Body Weight Fluctuation, and Cognitive Decline Among Older Adults. J Alzheimers Dis. 2021; 84(2):777-786.J Alzheimers Dis2021-01-01T00:00:002021Longitudinal Body Weight Change, Visit-To-Visit Body Weight Fluctuation, and Cognitive Decline Among Older Adults.Authorship 1406537334692986Roberts JS, Ferber R, Blacker D, Rumbaugh M, Grill JDAlzheimer's & dementia (New York, N. Y.)Disclosure of individual research results at federally funded Alzheimer's Disease Research Centers. Alzheimers Dement (N Y). 2021; 7(1):e12213.Alzheimers Dement (N Y)2021-10-14T00:00:002021Disclosure of individual research results at federally funded Alzheimer's Disease Research Centers.34792589Wang L, Laurentiev J, Yang J, Lo YC, Amariglio RE, Blacker D, Sperling RA, Marshall GA, Zhou LJAMA network openDevelopment and Validation of a Deep Learning Model for Earlier Detection of Cognitive Decline From Clinical Notes in Electronic Health Records. JAMA Netw Open. 2021 11 01; 4(11):e2135174.JAMA Netw Open2021-11-01T00:00:002021Development and Validation of a Deep Learning Model for Earlier Detection of Cognitive Decline From Clinical Notes in Electronic Health Records.34801383Wilkins JM, Locascio JJ, Gomez-Isla T, Hyman BT, Blacker D, Forester BP, Okereke OIThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric PsychiatryLongitudinal Changes in Neuropsychiatric Symptoms: Impact of Discrepancy in Everyday Preferences Between Persons With Cognitive Impairment and Their Care Partners. Am J Geriatr Psychiatry. 2022 05; 30(5):619-623.Am J Geriatr Psychiatry2021-10-24T00:00:002021Longitudinal Changes in Neuropsychiatric Symptoms: Impact of Discrepancy in Everyday Preferences Between Persons With Cognitive Impairment and Their Care Partners.Authorship 14098885Authorship 14121775Authorship 1414400634748116Yeh TS, Yuan C, Ascherio A, Rosner BA, Blacker D, Willett WCEuropean journal of epidemiologyLong-term intake of total energy and fat in relation to subjective cognitive decline. Eur J Epidemiol. 2022 Feb; 37(2):133-146.Eur J Epidemiol2021-11-08T00:00:002021Long-term intake of total energy and fat in relation to subjective cognitive decline.Authorship 1418313634873021Yeh TS, Yuan C, Ascherio A, Rosner BA, Willett WC, Blacker DNeurologyAuthor Response: Long-term Dietary Flavonoid Intake and Subjective Cognitive Decline in US Men and Women. Neurology. 2021 12 07; 97(23):1095.Neurology2021-12-07T00:00:002021Author Response: Long-term Dietary Flavonoid Intake and Subjective Cognitive Decline in US Men and Women.Authorship 1883161Authorship 14225802034971026Magdamo CG, Hong ZM, Noori A, Sheu YH, Deodhar M, Ye EM, Ge W, Sun H, Brenner L, Robbins GK, Mukerji S, Zafar SF, Benson N, Moura LMV, Hsu J, Arnold SE, Hyman BT, Serrano-Pozo A, Westover MB, Blacker D, Das SAlzheimer's & dementia : the journal of the Alzheimer's AssociationActive deep learning to detect cognitive concerns in electronic health records. Alzheimers Dement. 2021 Dec; 17 Suppl 11:e055362.Alzheimers Dement2021-12-01T00:00:002021Active deep learning to detect cognitive concerns in electronic health records.Authorship 2659283Authorship 14444901335404285Mozersky J, Roberts JS, Rumbaugh M, Chhatwal J, Wijsman E, Galasko D, Blacker DJournal of Alzheimer's disease : JADSpillover: The Approval of New Medications for Alzheimer's Disease Dementia Will Impact Biomarker Disclosure Among Asymptomatic Research Participants. J Alzheimers Dis. 2022; 90(3):1035-1043.J Alzheimers Dis2022-01-01T00:00:002022Spillover: The Approval of New Medications for Alzheimer's Disease Dementia Will Impact Biomarker Disclosure Among Asymptomatic Research Participants.35471691Ma Y, Sajeev G, VanderWeele TJ, Viswanathan A, Sigurdsson S, Eiriksdottir G, Aspelund T, Betensky RA, Grodstein F, Hofman A, Gudnason V, Launer L, Blacker DEuropean journal of epidemiologyAPOE e4 and late-life cognition: mediation by structural brain imaging markers. Eur J Epidemiol. 2022 Jun; 37(6):591-601.Eur J Epidemiol2022-04-26T00:00:002022APOE e4 and late-life cognition: mediation by structural brain imaging markers.Authorship 2975823Authorship 14542527Authorship 3663542true1Associate Professor of NeurologyAssociate Professor of Neurology35938255Rosen AC, Arias JJ, Ashford JW, Blacker D, Chhatwal JP, Chin NA, Clark L, Denny SS, Goldman JS, Gleason CE, Grill JD, Heidebrink JL, Henderson VW, Lavacot JA, Lingler JH, Menon M, Nosheny RL, Oliveira FF, Parker MW, Rahman-Filipiak A, Revoori A, Rumbaugh MC, Sanchez DL, Schindler SE, Schwarz CG, Toy L, Tyrone J, Walter S, Wang LS, Wijsman EM, Zallen DT, Aggarwal NTJournal of Alzheimer's disease : JADThe Advisory Group on Risk Evidence Education for Dementia: Multidisciplinary and Open to All. J Alzheimers Dis. 2022; 90(3):953-962.J Alzheimers Dis2022-01-01T00:00:002022The Advisory Group on Risk Evidence Education for Dementia: Multidisciplinary and Open to All.Authorship 3890191Authorship 1467532335730709Stites SD, Vogt NM, Blacker D, Rumbaugh M, Parker MWThe Journal of family practicePatients asking about APOE gene test results? Here's what to tell them. J Fam Pract. 2022 05; 71(4):E1-E7.J Fam Pract2022-05-01T00:00:002022Patients asking about APOE gene test results? Here's what to tell them.36040790Noori A, Magdamo C, Liu X, Tyagi T, Li Z, Kondepudi A, Alabsi H, Rudmann E, Wilcox D, Brenner L, Robbins GK, Moura L, Zafar S, Benson NM, Hsu J, R Dickson J, Serrano-Pozo A, Hyman BT, Blacker D, Westover MB, Mukerji SS, Das SJournal of medical Internet researchDevelopment and Evaluation of a Natural Language Processing Annotation Tool to Facilitate Phenotyping of Cognitive Status in Electronic Health Records: Diagnostic Study. J Med Internet Res. 2022 08 30; 24(8):e40384.J Med Internet Res2022-08-30T00:00:002022Development and Evaluation of a Natural Language Processing Annotation Tool to Facilitate Phenotyping of Cognitive Status in Electronic Health Records: Diagnostic Study.Authorship 14949514Authorship 14848124Authorship 14822833Authorship 14950903Authorship 14934822Authorship 14914484Authorship 149848019Authorship 1479255936043702Moura LMVR, Zafar S, Benson NM, Festa N, Price M, Donahue MA, Normand SL, Newhouse JP, Blacker D, Hsu JMedical careIdentifying Medicare Beneficiaries With Delirium. Med Care. 2022 11 01; 60(11):852-859.Med Care2022-08-31T00:00:002022Identifying Medicare Beneficiaries With Delirium.36186236Pantoja-Galicia N, Okereke OI, Blacker D, Betensky RABiostatistics & epidemiologyConcordance Measures and Time-Dependent ROC Methods. Biostat Epidemiol. 2021; 5(2):232-249.Biostat Epidemiol2021-05-25T00:00:002021Concordance Measures and Time-Dependent ROC Methods.35977320Festa N, Price M, Moura LMVR, Blacker D, Normand SL, Newhouse JP, Hsu JJAMA health forumEvaluation of Claims-Based Ascertainment of Alzheimer Disease and Related Dementias Across Health Care Settings. JAMA Health Forum. 2022 04; 3(4):e220653.JAMA Health Forum2022-04-22T00:00:002022Evaluation of Claims-Based Ascertainment of Alzheimer Disease and Related Dementias Across Health Care Settings.36162365Liu C, Murchland AR, VanderWeele TJ, Blacker DSocial science & medicine (1982)Eliminating racial disparities in dementia risk by equalizing education quality: A sensitivity analysis. Soc Sci Med. 2022 11; 312:115347.Soc Sci Med2022-09-12T00:00:002022Eliminating racial disparities in dementia risk by equalizing education quality: A sensitivity analysis.35968308Kelly DM, Anderson CD, Blacker D, Miller BL, Viswanathan AFrontiers in neurologyEditorial: The impact of chronic kidney disease on cognitive brain health. Front Neurol. 2022; 13:982740.Front Neurol2022-07-26T00:00:002022Editorial: The impact of chronic kidney disease on cognitive brain health.36496454Charpignon ML, Vakulenko-Lagun B, Zheng B, Magdamo C, Su B, Evans K, Rodriguez S, Sokolov A, Boswell S, Sheu YH, Somai M, Middleton L, Hyman BT, Betensky RA, Finkelstein SN, Welsch RE, Tzoulaki I, Blacker D, Das S, Albers MWNature communicationsCausal inference in medical records and complementary systems pharmacology for metformin drug repurposing towards dementia. Nat Commun. 2022 Dec 10; 13(1):7652.Nat Commun2022-12-10T00:00:002022Causal inference in medical records and complementary systems pharmacology for metformin drug repurposing towards dementia.36609056Wilkins JM, Locascio JJ, Gomez-Isla T, Hyman BT, Blacker D, Forester BP, Okereke OIThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric PsychiatryProjection of Care Partners' Preferences in the Proxy Assessments of Everyday Preferences for Persons With Cognitive Impairment. Am J Geriatr Psychiatry. 2023 04; 31(4):254-263.Am J Geriatr Psychiatry2022-12-11T00:00:002022Projection of Care Partners' Preferences in the Proxy Assessments of Everyday Preferences for Persons With Cognitive Impairment.Authorship 15139895Authorship 151067418Authorship 15121313Authorship 151203810Authorship 1512989936544249Moura LMVR, Donahue MA, Yan Z, Smith LH, Hsu J, Newhouse JP, Schwamm LH, Haneuse S, Hernandez-Diaz S, Blacker DStrokeComparative Effectiveness and Safety of Seizure Prophylaxis Among Adults After Acute Ischemic Stroke. Stroke. 2023 Feb; 54(2):527-536.Stroke2022-12-21T00:00:002022Comparative Effectiveness and Safety of Seizure Prophylaxis Among Adults After Acute Ischemic Stroke.36572369Moura LMVR, Yan Z, Donahue MA, Smith LH, Schwamm LH, Hsu J, Newhouse JP, Haneuse S, Blacker D, Hernandez-Diaz SJournal of clinical epidemiologyNo short-term mortality from benzodiazepine use post-acute ischemic stroke after accounting for bias. J Clin Epidemiol. 2023 02; 154:136-145.J Clin Epidemiol2022-12-23T00:00:002022No short-term mortality from benzodiazepine use post-acute ischemic stroke after accounting for bias.36548079Reeves SM, Williams V, Blacker D, Woods RLNeuropsychologyFurther evaluation of narrative description as a measure of cognitive function in Alzheimer's disease. Neuropsychology. 2023 Oct; 37(7):801-812.Neuropsychology2022-12-22T00:00:002022Further evaluation of narrative description as a measure of cognitive function in Alzheimer's disease.Authorship 1521657536724694Sheu YH, Magdamo C, Miller M, Smoller JW, Blacker DGeneral hospital psychiatryInitial antidepressant choice by non-psychiatrists: Learning from large-scale electronic health records. Gen Hosp Psychiatry. 2023 Mar-Apr; 81:22-31.Gen Hosp Psychiatry2022-12-12T00:00:002022Initial antidepressant choice by non-psychiatrists: Learning from large-scale electronic health records.Authorship 1760496Authorship 153384014Authorship 1533866736937522Kivisäkk P, Carlyle BC, Sweeney T, Trombetta BA, LaCasse K, El-Mufti L, Tuncali I, Chibnik LB, Das S, Scherzer CR, Johnson KA, Dickerson BC, Gomez-Isla T, Blacker D, Oakley DH, Frosch MP, Hyman BT, Aghvanyan A, Bathala P, Campbell C, Sigal G, Stengelin M, Arnold SEFrontiers in neurologyPlasma biomarkers for diagnosis of Alzheimer's disease and prediction of cognitive decline in individuals with mild cognitive impairment. Front Neurol. 2023; 14:1069411.Front Neurol2023-03-02T00:00:002023Plasma biomarkers for diagnosis of Alzheimer's disease and prediction of cognitive decline in individuals with mild cognitive impairment.36938854Flores-Torres MH, Christine CW, Bjornevik K, Molsberry SA, Hung AY, Healy BC, Blacker D, Schwarzschild MA, Ascherio AMovement disorders : official journal of the Movement Disorder SocietyLong-Term Intake of Folate, Vitamin B6, and Vitamin B12 and the Incidence of Parkinson's Disease in a Sample of U.S. Women and Men. Mov Disord. 2023 05; 38(5):866-879.Mov Disord2023-03-20T00:00:002023Long-Term Intake of Folate, Vitamin B6, and Vitamin B12 and the Incidence of Parkinson's Disease in a Sample of U.S. Women and Men.Authorship 216961437100858Sheu YH, Magdamo C, Miller M, Das S, Blacker D, Smoller JWNPJ digital medicineAI-assisted prediction of differential response to antidepressant classes using electronic health records. NPJ Digit Med. 2023 Apr 26; 6(1):73.NPJ Digit Med2023-04-26T00:00:002023AI-assisted prediction of differential response to antidepressant classes using electronic health records.37212116Vyas CM, Sadreyev RI, Gatchel JR, Kang JH, Reynolds CF, Mischoulon D, Chang G, Hazra A, Manson JE, Blacker D, De Vivo I, Okereke OIJournal of Alzheimer's disease : JADPilot Study of Second-Generation DNA Methylation Epigenetic Markers in Relation to Cognitive and Neuropsychiatric Symptoms in Older Adults. J Alzheimers Dis. 2023; 93(4):1563-1575.J Alzheimers Dis2023-01-01T00:00:002023Pilot Study of Second-Generation DNA Methylation Epigenetic Markers in Relation to Cognitive and Neuropsychiatric Symptoms in Older Adults.37247495Estiri H, Azhir A, Blacker DL, Ritchie CS, Patel CJ, Murphy SNEBioMedicineTemporal characterization of Alzheimer's Disease with sequences of clinical records. EBioMedicine. 2023 Jun; 92:104629.EBioMedicine2023-05-27T00:00:002023Temporal characterization of Alzheimer's Disease with sequences of clinical records.Authorship 15719773Authorship 15615856Authorship 155561153Authorship 15545193Authorship 15433065Authorship 156551910Authorship 1563703237066107Coelho LMG, Blacker D, Hsu J, Newhouse JP, Westover MB, Zafar SF, Moura LMVRNeurology. Clinical practiceAssociation of Early Seizure Prophylaxis With Posttraumatic Seizures and Mortality: A Meta-analysis With Evidence Quality Assessment. Neurol Clin Pract. 2023 Jun; 13(3):e200145.Neurol Clin Pract2023-03-30T00:00:002023Association of Early Seizure Prophylaxis With Posttraumatic Seizures and Mortality: A Meta-analysis With Evidence Quality Assessment.37315105Flores-Torres MH, Bjornevik K, Hung AY, Healy BC, Schwarzschild MA, Blacker D, Ascherio AMovement disorders : official journal of the Movement Disorder SocietySubjective Cognitive Decline in Women with Features Suggestive of Prodromal Parkinson's Disease. Mov Disord. 2023 08; 38(8):1473-1482.Mov Disord2023-06-14T00:00:002023Subjective Cognitive Decline in Women with Features Suggestive of Prodromal Parkinson's Disease.37130742Festa N, Moura LM, Blacker D, Newhouse JP, Hsu JBMJ evidence-based medicinePromise and peril of claims-based dementia ascertainment in causal inference. BMJ Evid Based Med. 2023 08; 28(4):222-225.BMJ Evid Based Med2023-05-02T00:00:002023Promise and peril of claims-based dementia ascertainment in causal inference.37461624Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, Kuksa PP, Li D, Lucio da Fonseca E, Mez JB, Palmer EL, Pillai J, Sherva RM, Song YE, Zhang X, Iqbal T, Pathak O, Valladares O, Kuzma AB, Abner E, Adams PM, Aguirre A, Albert MS, Albin RL, Allen M, Alvarez L, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Ayres G, Baldwin CT, Barber RC, Barnes LL, Barral S, Beach TG, Becker JT, Beecham GW, Beekly D, Benitez BA, Bennett D, Bertelson J, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Brewer J, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Chasse S, Chesselet MF, Chin NA, Chui HC, Chung J, Craft S, Crane PK, Cribbs DH, Crocco EA, Cruchaga C, Cuccaro ML, Cullum M, Darby E, Davis B, De Jager PL, DeCarli C, DeToledo J, Dick M, Dickson DW, Dombroski BA, Doody RS, Duara R, Ertekin-Taner N, Evans DA, Faber KM, Fairchild TJ, Fallon KB, Fardo DW, Farlow MR, Fernandez-Hernandez V, Ferris S, Foroud TM, Frosch MP, Fulton-Howard B, Galasko DR, Gamboa A, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Goate AM, Grabowski TJ, Graff-Radford NR, Green RC, Growdon JH, Hakonarson H, Hall J, Hamilton RL, Harari O, Hardy J, Harrell LE, Head E, Henderson VW, Hernandez M, Hohman T, Honig LS, Huebinger RM, Huentelman MJ, Hulette CM, Hyman BT, Hynan LS, Ibanez L, Jarvik GP, Jayadev S, Jin LW, Johnson K, Johnson L, Kamboh MI, Karydas AM, Katz MJ, Kauwe JS, Kaye JA, Keene CD, Khaleeq A, Kim R, Knebl J, Kowall NW, Kramer JH, Kukull WA, LaFerla FM, Lah JJ, Larson EB, Lerner A, Leverenz JB, Levey AI, Lieberman AP, Lipton RB, Logue M, Lopez OL, Lunetta KL, Lyketsos CG, Mains D, Margaret FE, Marson DC, Martin ERR, Martiniuk F, Mash DC, Masliah E, Massman P, Masurkar A, McCormick WC, McCurry SM, McDavid AN, McDonough S, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Monuki ES, Morris JC, Mukherjee S, Myers AJ, Nguyen T, O'Bryant S, Olichney JM, Ory M, Palmer R, Parisi JE, Paulson HL, Pavlik V, Paydarfar D, Perez V, Peskind E, Petersen RC, Pierce A, Polk M, Poon WW, Potter H, Qu L, Quiceno M, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reisch JS, Ringman JM, Roberson ED, Rodriguear M, Rogaeva E, Rosen HJ, Rosenberg RN, Royall DR, Sager MA, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Slifer SH, Small S, Smith AG, Smith JP, Sonnen JA, Spina S, St George-Hyslop P, Stern RA, Stevens AB, Strittmatter SM, Sultzer D, Swerdlow RH, Tanzi RE, Tilson JL, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, van Eldik LJ, Vance JM, Vardarajan BN, Vassar R, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Whitehead PL, Wijsman EM, Wilhelmsen KC, Williams B, Williamson J, Wilms H, Wingo TS, Wisniewski T, Woltjer RL, Woon M, Wright CB, Wu CK, Younkin SG, Yu CE, Yu L, Zhu X, Kunkle BW, Bush WS, Wang LS, Farrer LA, Haines JL, Mayeux R, Pericak-Vance MA, Schellenberg GD, Jun GR, Reitz C, Naj ACmedRxiv : the preprint server for health sciencesMulti-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK , GRB14 , and KIAA0825 as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium. medRxiv. 2023 Jul 08.medRxiv2023-07-08T00:00:002023Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK , GRB14 , and KIAA0825 as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium.37622323Wilkins JM, Locascio JJ, Gomez-Isla T, Hyman BT, Blacker D, Forester BP, Okereke OIInternational psychogeriatricsPotential impact of the COVID-19 pandemic on everyday preferences for persons with cognitive impairment. Int Psychogeriatr. 2023 Aug 25; 1-6.Int Psychogeriatr2023-08-25T00:00:002023Potential impact of the COVID-19 pandemic on everyday preferences for persons with cognitive impairment.Authorship 3593526Authorship 15855885Authorship 1586385437775316Kelly DM, Georgakis MK, Franceschini N, Blacker D, Viswanathan A, Anderson CDNeurologyInterplay Between Chronic Kidney Disease, Hypertension, and Stroke: Insights From a Multivariable Mendelian Randomization Analysis. Neurology. 2023 11 14; 101(20):e1960-e1969.Neurology2023-09-29T00:00:002023Interplay Between Chronic Kidney Disease, Hypertension, and Stroke: Insights From a Multivariable Mendelian Randomization Analysis.Authorship 1596817337812780Burns RB, Barry MJ, Blacker D, Kanjee ZAnnals of internal medicineWould You Screen This Patient for Cognitive Impairment? : Grand Rounds Discussion From Beth Israel Deaconess Medical Center. Ann Intern Med. 2023 10; 176(10):1405-1412.Ann Intern Med2023-10-10T00:00:002023Would You Screen This Patient for Cognitive Impairment? : Grand Rounds Discussion From Beth Israel Deaconess Medical Center.true1Professor of RadiologyProfessor of RadiologyAuthorship 4399445Authorship 16028651237869909Ma Y, Zhang Y, Coresh J, Viswanathan A, Sullivan KJ, Walker KA, Liu C, Lipsitz LA, Selvin E, Sharrett AR, Gottesman RF, Blacker D, Hofman A, Windham BG, Juraschek SPHypertension (Dallas, Tex. : 1979)Orthostatic Blood Pressure Change, Dizziness, and Risk of Dementia in the ARIC Study. Hypertension. 2024 Jan; 81(1):96-106.Hypertension2023-10-23T00:00:002023Orthostatic Blood Pressure Change, Dizziness, and Risk of Dementia in the ARIC Study.Authorship 4659694Authorship 4687814Authorship 513872true1Associate Professor of PsychiatryAssociate Professor of PsychiatryAuthorship 1632033638370813Sun S, Lomachinsky V, Smith LH, Newhouse JP, Westover MB, Blacker D, Schwamm L, Haneuse S, Moura LMVRmedRxiv : the preprint server for health sciencesBenzodiazepine Initiation and the Risk of Falls or Fall-Related Injuries in Older Adults Following Acute Ischemic Stroke. medRxiv. 2024 Feb 08.medRxiv2024-02-08T00:00:002024Benzodiazepine Initiation and the Risk of Falls or Fall-Related Injuries in Older Adults Following Acute Ischemic Stroke.Authorship 16345121538443298Burling JE, Katz Z, Yuan Z, Munro C, Mimmack K, Ma G, Hanseeuw BJ, Papp KV, Amariglio RE, Vannini P, Rentz DM, Quiroz YT, Johnson KA, Sperling RA, Blacker D, Marshall GA, Yang HS, Gatchel JRThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric PsychiatryStudy Partner Report of Apathy in Older Adults is Associated with AD Biomarkers: Findings from the Harvard Aging Brain Study. Am J Geriatr Psychiatry. 2024 Jan 28.Am J Geriatr Psychiatry2024-01-28T00:00:002024Study Partner Report of Apathy in Older Adults is Associated with AD Biomarkers: Findings from the Harvard Aging Brain Study.true1Professor of PsychiatryProfessor of Psychiatry3Professor in the Department of EpidemiologyProfessor in the Department of Epidemiology2Associate Chair of the Department of EpidemiologyAssociate Chair of the Department of Epidemiologytrue1Visiting ScientistVisiting Scientisttrue1Adjunct Professor of EpidemiologyAdjunct Professor of Epidemiologytrue1Associate Professor of PsychiatryAssociate Professor of PsychiatryAuthorship 5525197Authorship 5577465Authorship 5638106Authorship 2286439Authorship 2757975Authorship 3369155Authorship 4588506Authorship 4774574Authorship 3033318Authorship 6495081Authorship 649564223629586Macklin EA, Blacker D, Hyman BT, Betensky RAJournal of Alzheimer's disease : JADImproved design of prodromal Alzheimer's disease trials through cohort enrichment and surrogate endpoints. J Alzheimers Dis. 2013; 36(3):475-86.J Alzheimers Dis2013-01-01T00:00:002013Improved design of prodromal Alzheimer's disease trials through cohort enrichment and surrogate endpoints.23779081Blacker DJAMA neurologyFood for thought. JAMA Neurol. 2013 Aug; 70(8):967-8.JAMA Neurol2013-08-01T00:00:002013Food for thought.Authorship 65230146Authorship 544719423650207Fung WL, Naylor MG, Bennett DA, Lange C, Blacker DAmerican journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric GeneticsPrincipal components methods for narrow-sense heritability in the analysis of multidimensional longitudinal cognitive phenotypes. Am J Med Genet B Neuropsychiatr Genet. 2013 Oct; 162B(7):770-8.Am J Med Genet B Neuropsychiatr Genet2013-05-06T00:00:002013Principal components methods for narrow-sense heritability in the analysis of multidimensional longitudinal cognitive phenotypes.Authorship 2705682Authorship 6883795Authorship 693173623332671Zhu CW, Livote EE, Scarmeas N, Albert M, Brandt J, Blacker D, Sano M, Stern YAlzheimer's & dementia : the journal of the Alzheimer's AssociationLong-term associations between cholinesterase inhibitors and memantine use and health outcomes among patients with Alzheimer's disease. Alzheimers Dement. 2013 Nov; 9(6):733-40.Alzheimers Dement2013-01-17T00:00:002013Long-term associations between cholinesterase inhibitors and memantine use and health outcomes among patients with Alzheimer's disease.Authorship 2186101Authorship 6943674Authorship 69496512524162737Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thorton-Wells TA, Jones N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Gerrish A, Schmidt H, Kunkle B, Dunstan ML, Ruiz A, Bihoreau MT, Choi SH, Reitz C, Pasquier F, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Morón FJ, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MW, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuiness B, Larson EB, Green R, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, St George-Hyslop P, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Sanchez-Garcia F, Fox NC, Hardy J, Deniz Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Mancuso M, Matthews F, Moebus S, Mecocci P, Del Zompo M, Maier W, Hampel H, Pilotto A, Bullido M, Panza F, Caffarra P, Nacmias B, Gilbert JR, Mayhaus M, Lannefelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O'Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH, Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltuenen M, Martin ER, Schmidt R, Rujescu D, Wang LS, Dartigues JF, Mayeux R, Tzourio C, Hofman A, Nöthen MM, Graff C, Psaty BM, Jones L, Haines JL, Holmans PA, Lathrop M, Pericak-Vance MA, Launer LJ, Farrer LA, van Duijn CM, Van Broeckhoven C, Moskvina V, Seshadri S, Williams J, Schellenberg GD, Amouyel PNature geneticsMeta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet. 2013 Dec; 45(12):1452-8.Nat Genet2013-10-27T00:00:002013Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.24064468Razlighi QR, Stallard E, Brandt J, Blacker D, Albert M, Scarmeas N, Kinosian B, Yashin AI, Stern YJournal of Alzheimer's disease : JADA new algorithm for predicting time to disease endpoints in Alzheimer's disease patients. J Alzheimers Dis. 2014; 38(3):661-8.J Alzheimers Dis2014-01-01T00:00:002014A new algorithm for predicting time to disease endpoints in Alzheimer's disease patients.Authorship 700267424042430O'Brien J, Jackson JW, Grodstein F, Blacker D, Weuve JEpidemiologic reviewsPostmenopausal hormone therapy is not associated with risk of all-cause dementia and Alzheimer's disease. Epidemiol Rev. 2014; 36:83-103.Epidemiol Rev2013-09-15T00:00:002013Postmenopausal hormone therapy is not associated with risk of all-cause dementia and Alzheimer's disease.Authorship 25070511Authorship 703993224199751Swanson DM, Blacker D, Alchawa T, Ludwig KU, Mangold E, Lange CBMC geneticsProperties of permutation-based gene tests and controlling type 1 error using a summary statistic based gene test. BMC Genet. 2013 Nov 07; 14:108.BMC Genet2013-11-07T00:00:002013Properties of permutation-based gene tests and controlling type 1 error using a summary statistic based gene test.Authorship 3927101Authorship 3946373Authorship 4034646Authorship 18133824585367Serrano-Pozo A, Qian J, Monsell SE, Blacker D, Gómez-Isla T, Betensky RA, Growdon JH, Johnson KA, Frosch MP, Sperling RA, Hyman BTAnnals of neurologyMild to moderate Alzheimer dementia with insufficient neuropathological changes. Ann Neurol. 2014 Apr; 75(4):597-601.Ann Neurol2014-04-08T00:00:002014Mild to moderate Alzheimer dementia with insufficient neuropathological changes.Authorship 1901264Authorship 2804338Authorship 2897535Authorship 710625720625271Zhu CW, Livote EE, Kahle-Wrobleski K, Scarmeas N, Albert M, Brandt J, Blacker D, Sano M, Stern YAlzheimer disease and associated disordersLongitudinal medication usage in Alzheimer disease patients. Alzheimer Dis Assoc Disord. 2010 Oct-Dec; 24(4):354-9.Alzheimer Dis Assoc Disord2010-10-01T00:00:002010Longitudinal medication usage in Alzheimer disease patients.Authorship 2276125Authorship 2093216Authorship 7261564Authorship 3036318Authorship 1846463Authorship 2809949Authorship 73549014224922517Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, Jun G, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, Denning N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Schmidt H, Kunkle B, Dunstan ML, Vronskaya M, Johnson AD, Ruiz A, Bihoreau MT, Reitz C, Pasquier F, Hollingworth P, Hanon O, Fitzpatrick AL, Buxbaum JD, Campion D, Crane PK, Baldwin C, Becker T, Gudnason V, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Hernández I, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MJ, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuinness B, Larson EB, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, George-Hyslop PS, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Garcia FS, Fox NC, Hardy J, Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Scarpini E, Bonuccelli U, Mancuso M, Siciliano G, Moebus S, Mecocci P, Zompo MD, Maier W, Hampel H, Pilotto A, Frank-García A, Panza F, Solfrizzi V, Caffarra P, Nacmias B, Perry W, Mayhaus M, Lannfelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O'Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH, Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltunen M, Martin ER, Schmidt R, Rujescu D, Dartigues JF, Mayeux R, Tzourio C, Hofman A, Nöthen MM, Graff C, Psaty BM, Haines JL, Lathrop M, Pericak-Vance MA, Launer LJ, Van Broeckhoven C, Farrer LA, van Duijn CM, Ramirez A, Seshadri S, Schellenberg GD, Amouyel P, Williams JPloS oneGene-wide analysis detects two new susceptibility genes for Alzheimer's disease. PLoS One. 2014; 9(6):e94661.PLoS One2014-06-12T00:00:002014Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.Authorship 4341974Authorship 276648Authorship 3217511Authorship 36270410Authorship 3694291424698445Donovan NJ, Amariglio RE, Zoller AS, Rudel RK, Gomez-Isla T, Blacker D, Hyman BT, Locascio JJ, Johnson KA, Sperling RA, Marshall GA, Rentz DMThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric PsychiatrySubjective cognitive concerns and neuropsychiatric predictors of progression to the early clinical stages of Alzheimer disease. Am J Geriatr Psychiatry. 2014 Dec; 22(12):1642-51.Am J Geriatr Psychiatry2014-02-26T00:00:002014Subjective cognitive concerns and neuropsychiatric predictors of progression to the early clinical stages of Alzheimer disease.Authorship 7522157Authorship 748077424632990Sachdev P, Kalaria R, O'Brien J, Skoog I, Alladi S, Black SE, Blacker D, Blazer DG, Chen C, Chui H, Ganguli M, Jellinger K, Jeste DV, Pasquier F, Paulsen J, Prins N, Rockwood K, Roman G, Scheltens PAlzheimer disease and associated disordersDiagnostic criteria for vascular cognitive disorders: a VASCOG statement. Alzheimer Dis Assoc Disord. 2014 Jul-Sep; 28(3):206-18.Alzheimer Dis Assoc Disord2014-07-01T00:00:002014Diagnostic criteria for vascular cognitive disorders: a VASCOG statement.25140533Jackson JW, Schneeweiss S, VanderWeele TJ, Blacker DPloS oneQuantifying the role of adverse events in the mortality difference between first and second-generation antipsychotics in older adults: systematic review and meta-synthesis. PLoS One. 2014; 9(8):e105376.PLoS One2014-08-20T00:00:002014Quantifying the role of adverse events in the mortality difference between first and second-generation antipsychotics in older adults: systematic review and meta-synthesis.Authorship 5293407Authorship 547726Authorship 756833625212917Zoller AS, Gaal IM, Royer CA, Locascio JJ, Amariglio RE, Blacker D, Okereke OI, Johnson KA, Sperling RA, Rentz DM, Marshall GACurrent Alzheimer researchSIST-M-IR activities of daily living items that best discriminate clinically normal elderly from those with mild cognitive impairment. Curr Alzheimer Res. 2014; 11(8):785-91.Curr Alzheimer Res2014-01-01T00:00:002014SIST-M-IR activities of daily living items that best discriminate clinically normal elderly from those with mild cognitive impairment.Authorship 5590468Authorship 2174233Authorship 762048425234432Jackson JW, VanderWeele TJ, Viswanathan A, Blacker D, Schneeweiss SAmerican journal of epidemiologyThe explanatory role of stroke as a mediator of the mortality risk difference between older adults who initiate first- versus second-generation antipsychotic drugs. Am J Epidemiol. 2014 Oct 15; 180(8):847-52.Am J Epidemiol2014-09-18T00:00:002014The explanatory role of stroke as a mediator of the mortality risk difference between older adults who initiate first- versus second-generation antipsychotic drugs.Authorship 766947624251397Gu Y, Scarmeas N, Cosentino S, Brandt J, Albert M, Blacker D, Dubois B, Stern YCurrent Alzheimer researchChange in body mass index before and after Alzheimer's disease onset. Curr Alzheimer Res. 2014 May; 11(4):349-56.Curr Alzheimer Res2014-05-01T00:00:002014Change in body mass index before and after Alzheimer's disease onset.Authorship 4631644Authorship 7690154225199842Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, Baldwin CT, Jarvik GP, Crane PK, Rogaeva E, Barmada MM, Demirci FY, Cruchaga C, Kramer PL, Ertekin-Taner N, Hardy J, Graff-Radford NR, Green RC, Larson EB, St George-Hyslop PH, Buxbaum JD, Evans DA, Schneider JA, Lunetta KL, Kamboh MI, Saykin AJ, Reiman EM, De Jager PL, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Martin ER, Haines JL, Mayeux RP, Farrer LA, Schellenberg GD, Pericak-Vance MA, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barnes LL, Beach TG, Becker JT, Beekly D, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carney RM, Carrasquillo MM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Dick M, Dickson DW, Duara R, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lin CF, Lopez OL, Lyketsos CG, Mack WJ, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Murrell JR, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Valladares O, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu LJAMA neurologyEffects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. JAMA Neurol. 2014 Nov; 71(11):1394-404.JAMA Neurol2014-11-01T00:00:002014Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.Authorship 770002325048175Opoliner A, Carwile JL, Blacker D, Fitzmaurice GM, Austin SBArchives of women's mental healthEarly and late menarche and risk of depressive symptoms in young adulthood. Arch Womens Ment Health. 2014 Dec; 17(6):511-8.Arch Womens Ment Health2014-07-22T00:00:002014Early and late menarche and risk of depressive symptoms in young adulthood.Authorship 3645954Authorship 7721456Authorship 7730144Authorship 774182224656839Cosentino S, Zahodne LB, Brandt J, Blacker D, Albert M, Dubois B, Stern YAlzheimer's & dementia : the journal of the Alzheimer's AssociationSocial cognition in Alzheimer's disease: a separate construct contributing to dependence. Alzheimers Dement. 2014 Nov; 10(6):818-26.Alzheimers Dement2014-03-18T00:00:002014Social cognition in Alzheimer's disease: a separate construct contributing to dependence.25266297Sachdev PS, Blacker D, Blazer DG, Ganguli M, Jeste DV, Paulsen JS, Petersen RCNature reviews. NeurologyClassifying neurocognitive disorders: the DSM-5 approach. Nat Rev Neurol. 2014 Nov; 10(11):634-42.Nat Rev Neurol2014-09-30T00:00:002014Classifying neurocognitive disorders: the DSM-5 approach.Authorship 5366867Authorship 525341Authorship 5418641Authorship 2834307Authorship 2876586Authorship 7222910MAI2MohammadIkramMohammad Arfan Ikram79128Ikram, MohammadAdjunct Professor of EpidemiologyAuthorship 4277402Authorship 4934791Authorship 38729311Authorship 5170935Authorship 5401773Authorship 5133683Authorship 5675716Authorship 2297552Authorship 3279979Authorship 221331Authorship 821371Authorship 264175Authorship 2394139Authorship 2449038Authorship 3312804Authorship 4395101Authorship 475435Authorship 2311788Authorship 5443566Authorship 2461731Authorship 36484210Authorship 4294321Authorship 2664211326035686Jackson JW, VanderWeele TJ, Blacker D, Schneeweiss SEpidemiology (Cambridge, Mass.)Mediators of First- Versus Second-generation Antipsychotic-related Mortality in Older Adults. Epidemiology. 2015 Sep; 26(5):700-9.Epidemiology2015-09-01T00:00:002015Mediators of First- Versus Second-generation Antipsychotic-related Mortality in Older Adults.Authorship 2902136Authorship 5048391Authorship 7928164Authorship 8006012Authorship 79791055Authorship 806594625799928Power MC, Weuve J, Sharrett AR, Blacker D, Gottesman RFNature reviews. NeurologyStatins, cognition, and dementia—systematic review and methodological commentary. Nat Rev Neurol. 2015 Apr; 11(4):220-9.Nat Rev Neurol2015-03-24T00:00:002015Statins, cognition, and dementia—systematic review and methodological commentary.24637299Zhu CW, Scarmeas N, Ornstein K, Albert M, Brandt J, Blacker D, Sano M, Stern YAlzheimer's & dementia : the journal of the Alzheimer's AssociationHealth-care use and cost in dementia caregivers: Longitudinal results from the Predictors Caregiver Study. Alzheimers Dement. 2015 Apr; 11(4):444-54.Alzheimers Dement2014-03-15T00:00:002014Health-care use and cost in dementia caregivers: Longitudinal results from the Predictors Caregiver Study.23877336Opoliner A, Blacker D, Fitzmaurice G, Becker AThe International journal of social psychiatryChallenges in assessing depressive symptoms in Fiji: A psychometric evaluation of the CES-D. Int J Soc Psychiatry. 2014 Jun; 60(4):367-76.Int J Soc Psychiatry2013-07-22T00:00:002013Challenges in assessing depressive symptoms in Fiji: A psychometric evaluation of the CES-D.25531812Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, Tschanz JT, Munger RG, Corcoran CD, Rogaeva E, Lin CF, Dombroski BA, Cantwell LB, Partch A, Valladares O, Hakonarson H, St George-Hyslop P, Green RC, Goate AM, Foroud TM, Carney RM, Larson EB, Behrens TW, Kauwe JS, Haines JL, Farrer LA, Pericak-Vance MA, Mayeux R, Schellenberg GD, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barmada M, Barnes LL, Beach TG, Becker JT, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Burke JR, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carroll SL, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Demirci FY, Dick M, Dickson DW, Duara R, Ertekin-Taner N, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Graff-Radford NR, Growdon JH, Hamilton RL, Hamilton-Nelson KL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jarvik GP, Jicha GA, Jin LW, Jun G, Jun G, Kamboh MI, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lopez OL, Lunetta KL, Lyketsos CG, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam WM, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Murrell JR, Olichney JM, Parisi JE, Perry W, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu LJAMA neurologyRarity of the Alzheimer disease-protective APP A673T variant in the United States. JAMA Neurol. 2015 Feb; 72(2):209-16.JAMA Neurol2015-02-01T00:00:002015Rarity of the Alzheimer disease-protective APP A673T variant in the United States.Authorship 34333526Authorship 2644982Authorship 3272612Authorship 3396291Authorship 3745622Authorship 4707882Authorship 3541953Authorship 8220923Authorship 4703992Authorship 830782125442754Blacker DJ, Hankey GJInternal medicine journalPre-hospital stroke management: an Australian perspective. Intern Med J. 2014 Dec; 44(12a):1151-3.Intern Med J2014-12-01T00:00:002014Pre-hospital stroke management: an Australian perspective.Authorship 518386Authorship 886281Authorship 4925376Authorship 4934008Authorship 848841625626633Viswanathan A, Macklin EA, Betensky R, Hyman B, Smith EE, Blacker DAlzheimer disease and associated disordersThe Influence of Vascular Risk Factors and Stroke on Cognition in Late Life: Analysis of the NACC Cohort. Alzheimer Dis Assoc Disord. 2015 Oct-Dec; 29(4):287-93.Alzheimer Dis Assoc Disord2015-10-01T00:00:002015The Influence of Vascular Risk Factors and Stroke on Cognition in Late Life: Analysis of the NACC Cohort.Authorship 5222442Authorship 784962Authorship 86524245Authorship 93736622722634Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, Lincoln S, Bisceglio G, Georgescu C, Schultz D, Rakhshan F, Kolbert CP, Jen J, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N, Apostolova LG, Arnold SE, Baldwin CT, Barber R, Barmada MM, Beach T, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Burke JR, Buros J, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carney RM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cotman CW, Crane PK, Cruchaga C, Cummings JL, De Jager PL, DeCarli C, DeKosky ST, Demirci FY, Diaz-Arrastia R, Dick M, Dombroski BA, Duara R, Ellis WD, Evans D, Faber KM, Fallon KB, Farlow MR, Ferris S, Foroud TM, Frosch M, Galasko DR, Gallins PJ, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Goate AM, Green RC, Growdon JH, Hakonarson H, Hamilton RL, Hardy J, Harrell LE, Head E, Honig LS, Huentelman MJ, Hulette CM, Hyman BT, Jarvik GP, Jicha GA, Jin LW, Jun G, Kamboh MI, Karlawish J, Karydas A, Kauwe JS, Kaye JA, Kennedy N, Kim R, Koo EH, Kowall NW, Kramer P, Kukull WA, Lah JJ, Larson EB, Levey AI, Lieberman AP, Lopez OL, Lunetta KL, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Myers AJ, Naj AC, Nowotny P, Parisi JE, Perl DP, Peskind E, Poon WW, Potter H, Quinn JF, Raj A, Rajbhandary RA, Raskind M, Reiman EM, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley W, Shelanski ML, Slifer MA, Smith CD, Sonnen JA, Spina S, St George-Hyslop P, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, Vardarajan BN, Vinters HV, Vonsattel JP, Wang LS, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RLNeurologyNovel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology. 2012 Jul 17; 79(3):221-8.Neurology2012-06-20T00:00:002012Novel late-onset Alzheimer disease loci variants associate with brain gene expression.Authorship 8723011026973104Maye JE, Betensky RA, Gidicsin CM, Locascio J, Becker JA, Pepin L, Carmasin J, Rentz DM, Marshall GA, Blacker D, Sperling RA, Johnson KANeurobiology of agingMaternal dementia age at onset in relation to amyloid burden in non-demented elderly offspring. Neurobiol Aging. 2016 Apr; 40:61-67.Neurobiol Aging2015-12-28T00:00:002015Maternal dementia age at onset in relation to amyloid burden in non-demented elderly offspring.25843019Dagley A, LaPoint M, Huijbers W, Hedden T, McLaren DG, Chatwal JP, Papp KV, Amariglio RE, Blacker D, Rentz DM, Johnson KA, Sperling RA, Schultz APNeuroImageHarvard Aging Brain Study: Dataset and accessibility. Neuroimage. 2017 01; 144(Pt B):255-258.Neuroimage2015-04-03T00:00:002015Harvard Aging Brain Study: Dataset and accessibility.Authorship 3980396Authorship 8803301227060947Xiong L, Davidsdottir S, Reijmer YD, Shoamanesh A, Roongpiboonsopit D, Thanprasertsuk S, Martinez-Ramirez S, Charidimou A, Ayres AM, Fotiadis P, Gurol E, Blacker DL, Greenberg SM, Viswanathan AJournal of Alzheimer's disease : JADCognitive Profile and its Association with Neuroimaging Markers of Non-Demented Cerebral Amyloid Angiopathy Patients in a Stroke Unit. J Alzheimers Dis. 2016 03 08; 52(1):171-8.J Alzheimers Dis2016-03-08T00:00:002016Cognitive Profile and its Association with Neuroimaging Markers of Non-Demented Cerebral Amyloid Angiopathy Patients in a Stroke Unit.Authorship 8893761127028776Culley DJ, Flaherty D, Reddy S, Fahey MC, Rudolph J, Huang CC, Liu X, Xie Z, Bader AM, Hyman BT, Blacker D, Crosby GAnesthesia and analgesiaPreoperative Cognitive Stratification of Older Elective Surgical Patients: A Cross-Sectional Study. Anesth Analg. 2016 07; 123(1):186-92.Anesth Analg2016-07-01T00:00:002016Preoperative Cognitive Stratification of Older Elective Surgical Patients: A Cross-Sectional Study.2Assistant Professor1Associate Professor0Full Professor4Instructor5Other FacultyAuthorship 895317727227783Sajeev G, Weuve J, Jackson JW, VanderWeele TJ, Bennett DA, Grodstein F, Blacker DEpidemiology (Cambridge, Mass.)Late-life Cognitive Activity and Dementia: A Systematic Review and Bias Analysis. Epidemiology. 2016 09; 27(5):732-42.Epidemiology2016-09-01T00:00:002016Late-life Cognitive Activity and Dementia: A Systematic Review and Bias Analysis.Authorship 50092442015-02-28BLACKER, DEBORAH L.2008-08-01Small vessel disease and beta-amyloid deposition in mildly impaired cognitionR01NS0620282008-07-31BLACKER, DEBORAH L.1984-08-01Age-related changes of cognition in health and diseaseP01AG0049532025-06-30BLACKER, DEBORAH L.;KOENEN, KARESTAN C ;ONNELA, JUKKA-PEKKA1983-07-01Training Program in Psychiatric Genetics and Translational ResearchT32MH0171192025-12-31JOHNSON, KEITH A.;SPERLING, REISA A.2010-07-15Impact of Amyloid and Tau on the Aging Brain: The Harvard Aging Brain StudyP01AG0366942004-07-31BLACKER, DEBORAH L.1999-09-30GENETIC KNOWLEDGE AND ATTITUDES IN ALZHEIMER'S DISEASER01HG0018311999-05-31BLACKER, DEBORAH L.1993-09-01DEFINING CASENESS FOR PSYCHIATRIC LINKAGE STUDIESK21MH001118Principal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorCo-Principal InvestigatorAuthorship 9214679Authorship 9238963Authorship 928356627696605Dhilla Albers A, Asafu-Adjei J, Delaney MK, Kelly KE, Gomez-Isla T, Blacker D, Johnson KA, Sperling RA, Hyman BT, Betensky RA, Hastings L, Albers MWAnnals of neurologyEpisodic memory of odors stratifies Alzheimer biomarkers in normal elderly. Ann Neurol. 2016 12; 80(6):846-857.Ann Neurol2016-11-23T00:00:002016Episodic memory of odors stratifies Alzheimer biomarkers in normal elderly.26146610Dacks PA, Andrieu S, Blacker D, Carman AJ, Green AM, Grodstein F, Henderson VW, James BD, Lane RF, Lau J, Lin PJ, Reeves BC, Shah RC, Vellas B, Yaffe K, Yurko-Mauro K, Shineman DW, Bennett DA, Fillit HMThe journal of prevention of Alzheimer's diseaseDementia Prevention: optimizing the use of observational data for personal, clinical, and public health decision-making. J Prev Alzheimers Dis. 2014 Feb; 1(2):117-123.J Prev Alzheimers Dis2014-02-01T00:00:002014Dementia Prevention: optimizing the use of observational data for personal, clinical, and public health decision-making.Authorship 56269310Authorship 932236526998469Rentz DM, Dekhtyar M, Sherman J, Burnham S, Blacker D, Aghjayan SL, Papp KV, Amariglio RE, Schembri A, Chenhall T, Maruff P, Aisen P, Hyman BT, Sperling RAThe journal of prevention of Alzheimer's diseaseThe Feasibility of At-Home iPad Cognitive Testing For Use in Clinical Trials. J Prev Alzheimers Dis. 2016 Mar; 3(1):8-12.J Prev Alzheimers Dis2016-03-01T00:00:002016The Feasibility of At-Home iPad Cognitive Testing For Use in Clinical Trials.Authorship 581466Authorship 2013163Authorship 3507439Authorship 4217746Authorship 53999379433565Van Eerdewegh P, Santangelo SL, Lee H, Laird NM, Blacker DGenetic epidemiologyProbabilistic diagnosis in linkage analysis of bipolar disorder: putting weights on the fringe. Genet Epidemiol. 1997; 14(6):693-8.Genet Epidemiol1997-01-01T00:00:001997Probabilistic diagnosis in linkage analysis of bipolar disorder: putting weights on the fringe.9697696Blacker D, Wilcox MA, Laird NM, Rodes L, Horvath SM, Go RC, Perry R, Watson B, Bassett SS, McInnis MG, Albert MS, Hyman BT, Tanzi RENature geneticsAlpha-2 macroglobulin is genetically associated with Alzheimer disease. Nat Genet. 1998 Aug; 19(4):357-60.Nat Genet1998-08-01T00:00:001998Alpha-2 macroglobulin is genetically associated with Alzheimer disease.9811940Liao A, Nitsch RM, Greenberg SM, Finckh U, Blacker D, Albert M, Rebeck GW, Gomez-Isla T, Clatworthy A, Binetti G, Hock C, Mueller-Thomsen T, Mann U, Zuchowski K, Beisiegel U, Staehelin H, Growdon JH, Tanzi RE, Hyman BTHuman molecular geneticsGenetic association of an alpha2-macroglobulin (Val1000lle) polymorphism and Alzheimer's disease. Hum Mol Genet. 1998 Nov; 7(12):1953-6.Hum Mol Genet1998-11-01T00:00:001998Genetic association of an alpha2-macroglobulin (Val1000lle) polymorphism and Alzheimer's disease.11058432Lake SL, Blacker D, Laird NMAmerican journal of human geneticsFamily-based tests of association in the presence of linkage. Am J Hum Genet. 2000 Dec; 67(6):1515-25.Am J Hum Genet2000-10-31T00:00:002000Family-based tests of association in the presence of linkage.9453683Go RC, Duke LW, Harrell LE, Cody H, Bassett SS, Folstein MF, Albert MS, Foster JL, Sharrow NA, Blacker DJournal of geriatric psychiatry and neurologyDevelopment and validation of a Structured Telephone Interview for Dementia Assessment (STIDA): the NIMH Genetics Initiative. J Geriatr Psychiatry Neurol. 1997 Oct; 10(4):161-7.J Geriatr Psychiatry Neurol1997-10-01T00:00:001997Development and validation of a Structured Telephone Interview for Dementia Assessment (STIDA): the NIMH Genetics Initiative.9838272Laird NM, Blacker D, Wilcox MAmerican journal of human geneticsThe sib transmission/disequilibrium test is a Mantel-Haenszel test. Am J Hum Genet. 1998 Dec; 63(6):1915-6.Am J Hum Genet1998-12-01T00:00:001998The sib transmission/disequilibrium test is a Mantel-Haenszel test.11096271Mokliatchouk O, Blacker D, Rabinowitz DHuman heredityAssociation tests for traits with variable age at onset. Hum Hered. 2001; 51(1-2):46-53.Hum Hered2001-01-01T00:00:002001Association tests for traits with variable age at onset.17402816Albert M, Blacker D, Moss MB, Tanzi R, McArdle JJNeuropsychologyLongitudinal change in cognitive performance among individuals with mild cognitive impairment. Neuropsychology. 2007 Mar; 21(2):158-69.Neuropsychology2007-03-01T00:00:002007Longitudinal change in cognitive performance among individuals with mild cognitive impairment.19805487Siedlecki KL, Tatarina O, Sanders L, Albert M, Blacker D, Dubois B, Brandt J, Stern YThe journals of gerontology. Series B, Psychological sciences and social sciencesComparison of patient and caregiver reports of patient activity participation and its relationship to mental health in patients with Alzheimer's disease. J Gerontol B Psychol Sci Soc Sci. 2009 Nov; 64(6):687-95.J Gerontol B Psychol Sci Soc Sci2009-10-05T00:00:002009Comparison of patient and caregiver reports of patient activity participation and its relationship to mental health in patients with Alzheimer's disease.Authorship 97236712Authorship 9731951528318355Xiong L, Boulouis G, Charidimou A, Roongpiboonsopit D, Jessel MJ, Pasi M, Reijmer YD, Fotiadis P, Ayres A, Merrill E, Schwab K, Blacker D, Gurol ME, Greenberg SM, Viswanathan AJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and MetabolismDementia incidence and predictors in cerebral amyloid angiopathy patients without intracerebral hemorrhage. J Cereb Blood Flow Metab. 2018 02; 38(2):241-249.J Cereb Blood Flow Metab2017-03-20T00:00:002017Dementia incidence and predictors in cerebral amyloid angiopathy patients without intracerebral hemorrhage.28323826Qian J, Wolters FJ, Beiser A, Haan M, Ikram MA, Karlawish J, Langbaum JB, Neuhaus JM, Reiman EM, Roberts JS, Seshadri S, Tariot PN, Woods BM, Betensky RA, Blacker DPLoS medicineAPOE-related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohorts. PLoS Med. 2017 03; 14(3):e1002254.PLoS Med2017-03-21T00:00:002017APOE-related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohorts.11793685Bertram L, Hayward B, Lake SL, Falls K, Van Erdewegh P, Blacker DGenetic epidemiologyFamily-based tests of association in the presence and absence of known linkage. Genet Epidemiol. 2001; 21 Suppl 1:S292-7.Genet Epidemiol2001-01-01T00:00:002001Family-based tests of association in the presence and absence of known linkage.15829528Blacker DThe New England journal of medicineMild cognitive impairment--no benefit from vitamin E, little from donepezil. N Engl J Med. 2005 Jun 09; 352(23):2439-41.N Engl J Med2005-04-13T00:00:002005Mild cognitive impairment--no benefit from vitamin E, little from donepezil.16082692Go RC, Perry RT, Wiener H, Bassett SS, Blacker D, Devlin B, Sweet RAAmerican journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric GeneticsNeuregulin-1 polymorphism in late onset Alzheimer's disease families with psychoses. Am J Med Genet B Neuropsychiatr Genet. 2005 Nov 05; 139B(1):28-32.Am J Med Genet B Neuropsychiatr Genet2005-11-05T00:00:002005Neuregulin-1 polymorphism in late onset Alzheimer's disease families with psychoses.12103468Simon NM, Blacker D, Korbly NB, Sharma SG, Worthington JJ, Otto MW, Pollack MHJournal of affective disordersHypothyroidism and hyperthyroidism in anxiety disorders revisited: new data and literature review. J Affect Disord. 2002 May; 69(1-3):209-17.J Affect Disord2002-05-01T00:00:002002Hypothyroidism and hyperthyroidism in anxiety disorders revisited: new data and literature review.16685643McQueen MB, Blacker D, Laird NMAmerican journal of human geneticsVariance calculations for identity-by-descent estimation. Am J Hum Genet. 2006 Jun; 78(6):914-21.Am J Hum Genet2006-03-29T00:00:002006Variance calculations for identity-by-descent estimation.16773580Bertram L, Hsiao M, Lange C, Blacker D, Tanzi REAmerican journal of human geneticsSingle-nucleotide polymorphism rs498055 on chromosome 10q24 is not associated with Alzheimer disease in two independent family samples. Am J Hum Genet. 2006 Jul; 79(1):180-3; author reply 183-4.Am J Hum Genet2006-07-01T00:00:002006Single-nucleotide polymorphism rs498055 on chromosome 10q24 is not associated with Alzheimer disease in two independent family samples.16914696Zhu CW, Scarmeas N, Torgan R, Albert M, Brandt J, Blacker D, Sano M, Stern YNeurologyLongitudinal study of effects of patient characteristics on direct costs in Alzheimer disease. Neurology. 2006 Sep 26; 67(6):998-1005.Neurology2006-08-16T00:00:002006Longitudinal study of effects of patient characteristics on direct costs in Alzheimer disease.17209133Bertram L, Mullin K, Parkinson M, Hsiao M, Moscarillo TJ, Wagner SL, Becker KD, Velicelebi G, Blacker D, Tanzi REJournal of medical geneticsIs alpha-T catenin (VR22) an Alzheimer's disease risk gene? J Med Genet. 2007 Jan; 44(1):e63.J Med Genet2007-01-01T00:00:002007Is alpha-T catenin (VR22) an Alzheimer's disease risk gene?9384970Davidoff S, Mallya GK, Blacker DHarvard review of psychiatryTreatment of bipolar illness in an older, skeptical patient. Harv Rev Psychiatry. 1996 May-Jun; 4(1):39-44.Harv Rev Psychiatry1996-05-01T00:00:001996Treatment of bipolar illness in an older, skeptical patient.17725986Hamshere ML, Holmans PA, Avramopoulos D, Bassett SS, Blacker D, Bertram L, Wiener H, Rochberg N, Tanzi RE, Myers A, Wavrant-De Vrièze F, Go R, Fallin D, Lovestone S, Hardy J, Goate A, O'Donovan M, Williams J, Owen MJHuman molecular geneticsGenome-wide linkage analysis of 723 affected relative pairs with late-onset Alzheimer's disease. Hum Mol Genet. 2007 Nov 15; 16(22):2703-12.Hum Mol Genet2007-08-27T00:00:002007Genome-wide linkage analysis of 723 affected relative pairs with late-onset Alzheimer's disease.10597465Van Eerdewegh P, Dupuis J, Santangelo SL, Hayward LB, Blacker DGenetic epidemiologyThe importance of watching our weights: how the choice of weights for non-independent sib pairs can dramatically alter results. Genet Epidemiol. 1999; 17 Suppl 1:S373-8.Genet Epidemiol1999-01-01T00:00:001999The importance of watching our weights: how the choice of weights for non-independent sib pairs can dramatically alter results.11121190Collins JS, Perry RT, Watson B, Harrell LE, Acton RT, Blacker D, Albert MS, Tanzi RE, Bassett SS, McInnis MG, Campbell RD, Go RCAmerican journal of medical geneticsAssociation of a haplotype for tumor necrosis factor in siblings with late-onset Alzheimer disease: the NIMH Alzheimer Disease Genetics Initiative. Am J Med Genet. 2000 Dec 04; 96(6):823-30.Am J Med Genet2000-12-04T00:00:002000Association of a haplotype for tumor necrosis factor in siblings with late-onset Alzheimer disease: the NIMH Alzheimer Disease Genetics Initiative.9384967Blacker DHarvard review of psychiatryMaintenance treatment of major depression: a review of the literature. Harv Rev Psychiatry. 1996 May-Jun; 4(1):1-9.Harv Rev Psychiatry1996-05-01T00:00:001996Maintenance treatment of major depression: a review of the literature.18340692Rabins PV, Blacker D, Rovner BW, Rummans T, Schneider LS, Tariot PN, Blass DM, McIntyre JS, Charles SC, Anzia DJ, Cook IA, Finnerty MT, Johnson BR, Nininger JE, Schneidman B, Summergrad P, Woods SM, Berger J, Cross CD, Brandt HA, Margolis PM, Shemo JP, Blinder BJ, Duncan DL, Barnovitz MA, Carino AJ, Freyberg ZZ, Gray SH, Tonnu T, Kunkle R, Albert AB, Craig TJ, Regier DA, Fochtmann LJThe American journal of psychiatryAmerican Psychiatric Association practice guideline for the treatment of patients with Alzheimer's disease and other dementias. Second edition. Am J Psychiatry. 2007 Dec; 164(12 Suppl):5-56.Am J Psychiatry2007-12-01T00:00:002007American Psychiatric Association practice guideline for the treatment of patients with Alzheimer's disease and other dementias. Second edition.18510196Zhu CW, Torgan R, Scarmeas N, Albert M, Brandt J, Blacker D, Sano M, Stern YHome health care services quarterlyHome health and informal care utilization and costs over time in Alzheimer's disease. Home Health Care Serv Q. 2008; 27(1):1-20.Home Health Care Serv Q2008-01-01T00:00:002008Home health and informal care utilization and costs over time in Alzheimer's disease.18631979Zhu CW, Scarmeas N, Stavitsky K, Albert M, Brandt J, Blacker D, Sano M, Stern YAlzheimer's & dementia : the journal of the Alzheimer's AssociationComparison of costs of care between patients with Alzheimer's disease and dementia with Lewy bodies. Alzheimers Dement. 2008 Jul; 4(4):280-4.Alzheimers Dement2008-04-21T00:00:002008Comparison of costs of care between patients with Alzheimer's disease and dementia with Lewy bodies.12966032Saunders AJ, Bertram L, Mullin K, Sampson AJ, Latifzai K, Basu S, Jones J, Kinney D, MacKenzie-Ingano L, Yu S, Albert MS, Moscarillo TJ, Go RC, Bassett SS, Daly MJ, Laird NM, Wang X, Velicelebi G, Wagner SL, Becker DK, Tanzi RE, Blacker DHuman molecular geneticsGenetic association of Alzheimer's disease with multiple polymorphisms in alpha-2-macroglobulin. Hum Mol Genet. 2003 Nov 01; 12(21):2765-76.Hum Mol Genet2003-09-09T00:00:002003Genetic association of Alzheimer's disease with multiple polymorphisms in alpha-2-macroglobulin.149 13th StreetMassachusetts General HospitalGerontology Research/149-2691149 13th StreetCharlestown02129MA16013896Finn CT, Wilcox MA, Korf BR, Blacker D, Racette SR, Sklar P, Smoller JWThe Journal of clinical psychiatryPsychiatric genetics: a survey of psychiatrists' knowledge, opinions, and practice patterns. J Clin Psychiatry. 2005 Jul; 66(7):821-30.J Clin Psychiatry2005-07-01T00:00:002005Psychiatric genetics: a survey of psychiatrists' knowledge, opinions, and practice patterns.16378661Bertram L, Hsiao M, McQueen MB, Parkinson M, Mullin K, Blacker D, Tanzi RENeurobiology of agingThe LDLR locus in Alzheimer's disease: a family-based study and meta-analysis of case-control data. Neurobiol Aging. 2007 Jan; 28(1):18.e1-4.Neurobiol Aging2005-12-27T00:00:002005The LDLR locus in Alzheimer's disease: a family-based study and meta-analysis of case-control data.16436560Blacker DEvidence-based mental healthNeither vitamin E nor donepezil delays progression from amnestic mild cognitive impairment to Alzheimer's disease in the long term. Evid Based Ment Health. 2006 Feb; 9(1):20.Evid Based Ment Health2006-02-01T00:00:002006Neither vitamin E nor donepezil delays progression from amnestic mild cognitive impairment to Alzheimer's disease in the long term.17086514Rakovski CS, Xu X, Lazarus R, Blacker D, Laird NMGenetic epidemiologyA new multimarker test for family-based association studies. Genet Epidemiol. 2007 Jan; 31(1):9-17.Genet Epidemiol2007-01-01T00:00:002007A new multimarker test for family-based association studies.17056633Johnson KA, Moran EK, Becker JA, Blacker D, Fischman AJ, Albert MSJournal of neurology, neurosurgery, and psychiatrySingle photon emission computed tomography perfusion differences in mild cognitive impairment. J Neurol Neurosurg Psychiatry. 2007 Mar; 78(3):240-7.J Neurol Neurosurg Psychiatry2006-10-20T00:00:002006Single photon emission computed tomography perfusion differences in mild cognitive impairment.17999200Fennema-Notestine C, Gamst AC, Quinn BT, Pacheco J, Jernigan TL, Thal L, Buckner R, Killiany R, Blacker D, Dale AM, Fischl B, Dickerson B, Gollub RLNeuroinformaticsFeasibility of multi-site clinical structural neuroimaging studies of aging using legacy data. Neuroinformatics. 2007; 5(4):235-45.Neuroinformatics2007-11-13T00:00:002007Feasibility of multi-site clinical structural neuroimaging studies of aging using legacy data.17192785Bertram L, McQueen MB, Mullin K, Blacker D, Tanzi RENature geneticsSystematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. Nat Genet. 2007 Jan; 39(1):17-23.Nat Genet2007-01-01T00:00:002007Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database.18414124Breslau J, Javaras KN, Blacker D, Murphy JM, Normand SLThe Journal of nervous and mental diseaseDifferential item functioning between ethnic groups in the epidemiological assessment of depression. J Nerv Ment Dis. 2008 Apr; 196(4):297-306.J Nerv Ment Dis2008-04-01T00:00:002008Differential item functioning between ethnic groups in the epidemiological assessment of depression.15351768Liu IC, Blacker DL, Xu R, Fitzmaurice G, Lyons MJ, Tsuang MTArchives of general psychiatryGenetic and environmental contributions to the development of alcohol dependence in male twins. Arch Gen Psychiatry. 2004 Sep; 61(9):897-903.Arch Gen Psychiatry2004-09-01T00:00:002004Genetic and environmental contributions to the development of alcohol dependence in male twins.11072133Buxbaum JD, Lilliehook C, Chan JY, Go RC, Bassett SS, Tanzi RE, Wasco W, Blacker DNeuroscience lettersGenomic structure, expression pattern, and chromosomal localization of the human calsenilin gene: no association between an exonic polymorphism and Alzheimer's disease. Neurosci Lett. 2000 Nov 24; 294(3):135-8.Neurosci Lett2000-11-24T00:00:002000Genomic structure, expression pattern, and chromosomal localization of the human calsenilin gene: no association between an exonic polymorphism and Alzheimer's disease.Authorship 9940911028697559Gatchel JR, Donovan NJ, Locascio JJ, Schultz AP, Becker JA, Chhatwal J, Papp KV, Amariglio RE, Rentz DM, Blacker D, Sperling RA, Johnson KA, Marshall GAJournal of Alzheimer's disease : JADDepressive Symptoms and Tau Accumulation in the Inferior Temporal Lobe and Entorhinal Cortex in Cognitively Normal Older Adults: A Pilot Study. J Alzheimers Dis. 2017; 59(3):975-985.J Alzheimers Dis2017-01-01T00:00:002017Depressive Symptoms and Tau Accumulation in the Inferior Temporal Lobe and Entorhinal Cortex in Cognitively Normal Older Adults: A Pilot Study.18840808Scherer RK, Scarmeas N, Brandt J, Blacker D, Albert MS, Stern YThe journals of gerontology. Series A, Biological sciences and medical sciencesThe relation of patient dependence to home health aide use in Alzheimer's disease. J Gerontol A Biol Sci Med Sci. 2008 Sep; 63(9):1005-9.J Gerontol A Biol Sci Med Sci2008-09-01T00:00:002008The relation of patient dependence to home health aide use in Alzheimer's disease.19112067Desikan RS, Cabral HJ, Fischl B, Guttmann CR, Blacker D, Hyman BT, Albert MS, Killiany RJAJNR. American journal of neuroradiologyTemporoparietal MR imaging measures of atrophy in subjects with mild cognitive impairment that predict subsequent diagnosis of Alzheimer disease. AJNR Am J Neuroradiol. 2009 Mar; 30(3):532-8.AJNR Am J Neuroradiol2008-12-26T00:00:002008Temporoparietal MR imaging measures of atrophy in subjects with mild cognitive impairment that predict subsequent diagnosis of Alzheimer disease.16880361Blacker D, Lovestone SJournal of geriatric psychiatry and neurologyGenetics and dementia nosology. J Geriatr Psychiatry Neurol. 2006 Sep; 19(3):186-91.J Geriatr Psychiatry Neurol2006-09-01T00:00:002006Genetics and dementia nosology.9520001Blacker D, Tanzi REArchives of neurologyThe genetics of Alzheimer disease: current status and future prospects. Arch Neurol. 1998 Mar; 55(3):294-6.Arch Neurol1998-03-01T00:00:001998The genetics of Alzheimer disease: current status and future prospects.11113613Bertram L, Blacker D, Crystal A, Mullin K, Keeney D, Jones J, Basu S, Yhu S, Guénette S, McInnis M, Go R, Tanzi RExperimental gerontologyCandidate genes showing no evidence for association or linkage with Alzheimer's disease using family-based methodologies. Exp Gerontol. 2000 Dec; 35(9-10):1353-61.Exp Gerontol2000-12-01T00:00:002000Candidate genes showing no evidence for association or linkage with Alzheimer's disease using family-based methodologies.20975515Zhu CW, Livote EE, Kahle-Wrobleski K, Scarmeas N, Albert M, Brandt J, Blacker D, Sano M, Stern YAlzheimer disease and associated disordersUtilization of antihypertensives, antidepressants, antipsychotics, and hormones in Alzheimer disease. Alzheimer Dis Assoc Disord. 2011 Apr-Jun; 25(2):144-8.Alzheimer Dis Assoc Disord2011-04-01T00:00:002011Utilization of antihypertensives, antidepressants, antipsychotics, and hormones in Alzheimer disease.Authorship 100287111428714976Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, Sleegers K, Vronskaya M, Ruiz A, Graham RR, Olaso R, Hoffmann P, Grove ML, Vardarajan BN, Hiltunen M, Nöthen MM, White CC, Hamilton-Nelson KL, Epelbaum J, Maier W, Choi SH, Beecham GW, Dulary C, Herms S, Smith AV, Funk CC, Derbois C, Forstner AJ, Ahmad S, Li H, Bacq D, Harold D, Satizabal CL, Valladares O, Squassina A, Thomas R, Brody JA, Qu L, Sánchez-Juan P, Morgan T, Wolters FJ, Zhao Y, Garcia FS, Denning N, Fornage M, Malamon J, Naranjo MCD, Majounie E, Mosley TH, Dombroski B, Wallon D, Lupton MK, Dupuis J, Whitehead P, Fratiglioni L, Medway C, Jian X, Mukherjee S, Keller L, Brown K, Lin H, Cantwell LB, Panza F, McGuinness B, Moreno-Grau S, Burgess JD, Solfrizzi V, Proitsi P, Adams HH, Allen M, Seripa D, Pastor P, Cupples LA, Price ND, Hannequin D, Frank-García A, Levy D, Chakrabarty P, Caffarra P, Giegling I, Beiser AS, Giedraitis V, Hampel H, Garcia ME, Wang X, Lannfelt L, Mecocci P, Eiriksdottir G, Crane PK, Pasquier F, Boccardi V, Henández I, Barber RC, Scherer M, Tarraga L, Adams PM, Leber M, Chen Y, Albert MS, Riedel-Heller S, Emilsson V, Beekly D, Braae A, Schmidt R, Blacker D, Masullo C, Schmidt H, Doody RS, Spalletta G, Longstreth WT, Fairchild TJ, Bossù P, Lopez OL, Frosch MP, Sacchinelli E, Ghetti B, Yang Q, Huebinger RM, Jessen F, Li S, Kamboh MI, Morris J, Sotolongo-Grau O, Katz MJ, Corcoran C, Dunstan M, Braddel A, Thomas C, Meggy A, Marshall R, Gerrish A, Chapman J, Aguilar M, Taylor S, Hill M, Fairén MD, Hodges A, Vellas B, Soininen H, Kloszewska I, Daniilidou M, Uphill J, Patel Y, Hughes JT, Lord J, Turton J, Hartmann AM, Cecchetti R, Fenoglio C, Serpente M, Arcaro M, Caltagirone C, Orfei MD, Ciaramella A, Pichler S, Mayhaus M, Gu W, Lleó A, Fortea J, Blesa R, Barber IS, Brookes K, Cupidi C, Maletta RG, Carrell D, Sorbi S, Moebus S, Urbano M, Pilotto A, Kornhuber J, Bosco P, Todd S, Craig D, Johnston J, Gill M, Lawlor B, Lynch A, Fox NC, Hardy J, Albin RL, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Baldwin CT, Barnes LL, Barral S, Beach TG, Becker JT, Bigio EH, Bird TD, Boeve BF, Bowen JD, Boxer A, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Carroll SL, Diaz CC, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, Dick M, Duara R, Evans DA, Faber KM, Fallon KB, Fardo DW, Farlow MR, Ferris S, Foroud TM, Galasko DR, Gearing M, Geschwind DH, Gilbert JR, Graff-Radford NR, Green RC, Growdon JH, Hamilton RL, Harrell LE, Honig LS, Huentelman MJ, Hulette CM, Hyman BT, Jarvik GP, Abner E, Jin LW, Jun G, Karydas A, Kaye JA, Kim R, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lunetta KL, Lyketsos CG, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Morris JC, Murrell JR, Myers AJ, O'Bryant S, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Perry W, Peskind E, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, Rosen HJ, Rosenberg RN, Sager MA, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Swerdlow RH, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Wilhelmsen KC, Williamson J, Wingo TS, Woltjer RL, Wright CB, Yu CE, Yu L, Garzia F, Golamaully F, Septier G, Engelborghs S, Vandenberghe R, De Deyn PP, Fernadez CM, Benito YA, Thonberg H, Forsell C, Lilius L, Kinhult-Stählbom A, Kilander L, Brundin R, Concari L, Helisalmi S, Koivisto AM, Haapasalo A, Dermecourt V, Fievet N, Hanon O, Dufouil C, Brice A, Ritchie K, Dubois B, Himali JJ, Keene CD, Tschanz J, Fitzpatrick AL, Kukull WA, Norton M, Aspelund T, Larson EB, Munger R, Rotter JI, et alNature geneticsRare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nat Genet. 2017 09; 49(9):1373-1384.Nat Genet2017-07-17T00:00:002017Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.20808152Blacker DThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric PsychiatryBeyond the dawning of the age of biomarkers. Am J Geriatr Psychiatry. 2010 Nov; 18(11):955-8.Am J Geriatr Psychiatry2010-11-01T00:00:002010Beyond the dawning of the age of biomarkers.16216946Scarmeas N, Brandt J, Albert M, Hadjigeorgiou G, Papadimitriou A, Dubois B, Sarazin M, Devanand D, Honig L, Marder K, Bell K, Wegesin D, Blacker D, Stern YArchives of neurologyDelusions and hallucinations are associated with worse outcome in Alzheimer disease. Arch Neurol. 2005 Oct; 62(10):1601-8.Arch Neurol2005-10-01T00:00:002005Delusions and hallucinations are associated with worse outcome in Alzheimer disease.9427016Blacker DHarvard review of psychiatryThe genetics of Alzheimer's disease: progress, possibilities, and pitfalls. Harv Rev Psychiatry. 1997 Nov-Dec; 5(4):234-7.Harv Rev Psychiatry1997-11-01T00:00:001997The genetics of Alzheimer's disease: progress, possibilities, and pitfalls.Authorship 101056210Authorship 10104512Authorship 10106652028906204Charidimou A, Blacker D, Viswanathan AInternational journal of stroke : official journal of the International Stroke SocietyContext is everything: From cardiovascular disease to cerebral microbleeds. Int J Stroke. 2018 01; 13(1):6-10.Int J Stroke2017-09-14T00:00:002017Context is everything: From cardiovascular disease to cerebral microbleeds.22188854Ma H, Parsons MW, Christensen S, Campbell BC, Churilov L, Connelly A, Yan B, Bladin C, Phan T, Barber AP, Read S, Hankey GJ, Markus R, Wijeratne T, Grimley R, Mahant N, Kleinig T, Sturm J, Lee A, Blacker D, Gerraty R, Krause M, Desmond PM, McBride SJ, Carey L, Howells DW, Hsu CY, Davis SM, Donnan GAInternational journal of stroke : official journal of the International Stroke SocietyA multicentre, randomized, double-blinded, placebo-controlled Phase III study to investigate EXtending the time for Thrombolysis in Emergency Neurological Deficits (EXTEND). Int J Stroke. 2012 Jan; 7(1):74-80.Int J Stroke2012-01-01T00:00:002012A multicentre, randomized, double-blinded, placebo-controlled Phase III study to investigate EXtending the time for Thrombolysis in Emergency Neurological Deficits (EXTEND).28891828Culley DJ, Flaherty D, Fahey MC, Rudolph JL, Javedan H, Huang CC, Wright J, Bader AM, Hyman BT, Blacker D, Crosby GAnesthesiologyPoor Performance on a Preoperative Cognitive Screening Test Predicts Postoperative Complications in Older Orthopedic Surgical Patients. Anesthesiology. 2017 11; 127(5):765-774.Anesthesiology2017-11-01T00:00:002017Poor Performance on a Preoperative Cognitive Screening Test Predicts Postoperative Complications in Older Orthopedic Surgical Patients.12490529Blacker D, Bertram L, Saunders AJ, Moscarillo TJ, Albert MS, Wiener H, Perry RT, Collins JS, Harrell LE, Go RC, Mahoney A, Beaty T, Fallin MD, Avramopoulos D, Chase GA, Folstein MF, McInnis MG, Bassett SS, Doheny KJ, Pugh EW, Tanzi REHuman molecular geneticsResults of a high-resolution genome screen of 437 Alzheimer's disease families. Hum Mol Genet. 2003 Jan 01; 12(1):23-32.Hum Mol Genet2003-01-01T00:00:002003Results of a high-resolution genome screen of 437 Alzheimer's disease families.17579348McQueen MB, Bertram L, Lange C, Becker KD, Albert MS, Tanzi RE, Blacker DAmerican journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric GeneticsExploring candidate gene associations with neuropsychological performance. Am J Med Genet B Neuropsychiatr Genet. 2007 Dec 05; 144B(8):987-91.Am J Med Genet B Neuropsychiatr Genet2007-12-05T00:00:002007Exploring candidate gene associations with neuropsychological performance.17716075Albert MS, Blacker DAnnual review of clinical psychologyMild cognitive impairment and dementia. Annu Rev Clin Psychol. 2006; 2:379-88.Annu Rev Clin Psychol2006-01-01T00:00:002006Mild cognitive impairment and dementia.18401023Cosentino S, Scarmeas N, Helzner E, Glymour MM, Brandt J, Albert M, Blacker D, Stern YNeurologyAPOE epsilon 4 allele predicts faster cognitive decline in mild Alzheimer disease. Neurology. 2008 May 06; 70(19 Pt 2):1842-9.Neurology2008-04-09T00:00:002008APOE epsilon 4 allele predicts faster cognitive decline in mild Alzheimer disease.21705906Power MC, Weuve J, Gagne JJ, McQueen MB, Viswanathan A, Blacker DEpidemiology (Cambridge, Mass.)The association between blood pressure and incident Alzheimer disease: a systematic review and meta-analysis. Epidemiology. 2011 Sep; 22(5):646-59.Epidemiology2011-09-01T00:00:002011The association between blood pressure and incident Alzheimer disease: a systematic review and meta-analysis.1415815Blacker D, Tsuang MTThe American journal of psychiatryContested boundaries of bipolar disorder and the limits of categorical diagnosis in psychiatry. Am J Psychiatry. 1992 Nov; 149(11):1473-83.Am J Psychiatry1992-11-01T00:00:001992Contested boundaries of bipolar disorder and the limits of categorical diagnosis in psychiatry.15500593Liu IC, Blacker DL, Xu R, Fitzmaurice G, Tsuang MT, Lyons MJAddiction (Abingdon, England)Genetic and environmental contributions to age of onset of alcohol dependence symptoms in male twins. Addiction. 2004 Nov; 99(11):1403-9.Addiction2004-11-01T00:00:002004Genetic and environmental contributions to age of onset of alcohol dependence symptoms in male twins.15745979Bertram L, Hiltunen M, Parkinson M, Ingelsson M, Lange C, Ramasamy K, Mullin K, Menon R, Sampson AJ, Hsiao MY, Elliott KJ, Velicelebi G, Moscarillo T, Hyman BT, Wagner SL, Becker KD, Blacker D, Tanzi REThe New England journal of medicineFamily-based association between Alzheimer's disease and variants in UBQLN1. N Engl J Med. 2005 Mar 03; 352(9):884-94.N Engl J Med2005-03-03T00:00:002005Family-based association between Alzheimer's disease and variants in UBQLN1.15768051Bertram L, Hsiao M, Mullin K, Parkinson M, Menon R, Moscarillo TJ, Blacker D, Tanzi REMolecular psychiatryACAT1 is not associated with Alzheimer's disease in two independent family-based samples. Mol Psychiatry. 2005 Jun; 10(6):522-4.Mol Psychiatry2005-06-01T00:00:002005ACAT1 is not associated with Alzheimer's disease in two independent family-based samples.17380059Moscarillo TJ, Holt H, Perman M, Goldberg S, Cortellini L, Stoler JM, DeJong W, Miles BJ, Albert MS, Go RC, Blacker DCommunity geneticsKnowledge of and attitudes about Alzheimer disease genetics: report of a pilot survey and two focus groups. Community Genet. 2007; 10(2):97-102.Community Genet2007-01-01T00:00:002007Knowledge of and attitudes about Alzheimer disease genetics: report of a pilot survey and two focus groups.14635173Goldin LR, Camp NJ, Keen KJ, Martin LJ, Moslehi R, Ghosh S, North KE, Wyszynski DF, Blacker DGenetic epidemiologyAnalysis of metabolic syndrome phenotypes in Framingham Heart Study families from Genetic Analysis Workshop 13. Genet Epidemiol. 2003; 25 Suppl 1:S78-89.Genet Epidemiol2003-01-01T00:00:002003Analysis of metabolic syndrome phenotypes in Framingham Heart Study families from Genetic Analysis Workshop 13.Authorship 1017754729036824Dumurgier J, Hanseeuw BJ, Hatling FB, Judge KA, Schultz AP, Chhatwal JP, Blacker D, Sperling RA, Johnson KA, Hyman BT, Gómez-Isla TJournal of Alzheimer's disease : JADAlzheimer's Disease Biomarkers and Future Decline in Cognitive Normal Older Adults. J Alzheimers Dis. 2017; 60(4):1451-1459.J Alzheimers Dis2017-01-01T00:00:002017Alzheimer's Disease Biomarkers and Future Decline in Cognitive Normal Older Adults.15554581Monuteaux MC, Fitzmaurice G, Blacker D, Buka SL, Biederman JPsychological medicineSpecificity in the familial aggregation of overt and covert conduct disorder symptoms in a referred attention-deficit hyperactivity disorder sample. Psychol Med. 2004 Aug; 34(6):1113-27.Psychol Med2004-08-01T00:00:002004Specificity in the familial aggregation of overt and covert conduct disorder symptoms in a referred attention-deficit hyperactivity disorder sample.15911793Scarmeas N, Albert M, Brandt J, Blacker D, Hadjigeorgiou G, Papadimitriou A, Dubois B, Sarazin M, Wegesin D, Marder K, Bell K, Honig L, Stern YNeurologyMotor signs predict poor outcomes in Alzheimer disease. Neurology. 2005 May 24; 64(10):1696-703.Neurology2005-05-24T00:00:002005Motor signs predict poor outcomes in Alzheimer disease.17021177Celone KA, Calhoun VD, Dickerson BC, Atri A, Chua EF, Miller SL, DePeau K, Rentz DM, Selkoe DJ, Blacker D, Albert MS, Sperling RAThe Journal of neuroscience : the official journal of the Society for NeuroscienceAlterations in memory networks in mild cognitive impairment and Alzheimer's disease: an independent component analysis. J Neurosci. 2006 Oct 04; 26(40):10222-31.J Neurosci2006-10-04T00:00:002006Alterations in memory networks in mild cognitive impairment and Alzheimer's disease: an independent component analysis.18672473Desikan RS, Fischl B, Cabral HJ, Kemper TL, Guttmann CR, Blacker D, Hyman BT, Albert MS, Killiany RJNeurologyMRI measures of temporoparietal regions show differential rates of atrophy during prodromal AD. Neurology. 2008 Sep 09; 71(11):819-25.Neurology2008-07-30T00:00:002008MRI measures of temporoparietal regions show differential rates of atrophy during prodromal AD.16273315Liu IC, Xu R, Blacker DL, Fitzmaurice G, Lyons MJ, Tsuang MTBehavior geneticsThe application of a random effects model to censored twin data. Behav Genet. 2005 Nov; 35(6):781-9.Behav Genet2005-11-01T00:00:002005The application of a random effects model to censored twin data.17034007Perry RT, Wiener H, Harrell LE, Blacker D, Tanzi RE, Bertram L, Bassett SS, Go RCAmerican journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric GeneticsFollow-up mapping supports the evidence for linkage in the candidate region at 9q22 in the NIMH Alzheimer's disease Genetics Initiative cohort. Am J Med Genet B Neuropsychiatr Genet. 2007 Mar 05; 144B(2):220-7.Am J Med Genet B Neuropsychiatr Genet2007-03-05T00:00:002007Follow-up mapping supports the evidence for linkage in the candidate region at 9q22 in the NIMH Alzheimer's disease Genetics Initiative cohort.11198280Bertram L, Guénette S, Jones J, Keeney D, Mullin K, Crystal A, Basu S, Yhu S, Deng A, Rebeck GW, Hyman BT, Go R, McInnis M, Blacker D, Tanzi RAnnals of neurologyNo evidence for genetic association or linkage of the cathepsin D (CTSD) exon 2 polymorphism and Alzheimer disease. Ann Neurol. 2001 Jan; 49(1):114-6.Ann Neurol2001-01-01T00:00:002001No evidence for genetic association or linkage of the cathepsin D (CTSD) exon 2 polymorphism and Alzheimer disease.18056553Dickerson BC, Sperling RA, Hyman BT, Albert MS, Blacker DArchives of general psychiatryClinical prediction of Alzheimer disease dementia across the spectrum of mild cognitive impairment. Arch Gen Psychiatry. 2007 Dec; 64(12):1443-50.Arch Gen Psychiatry2007-12-01T00:00:002007Clinical prediction of Alzheimer disease dementia across the spectrum of mild cognitive impairment.20463288O'Brien JL, O'Keefe KM, LaViolette PS, DeLuca AN, Blacker D, Dickerson BC, Sperling RANeurologyLongitudinal fMRI in elderly reveals loss of hippocampal activation with clinical decline. Neurology. 2010 Jun 15; 74(24):1969-76.Neurology2010-05-12T00:00:002010Longitudinal fMRI in elderly reveals loss of hippocampal activation with clinical decline.16175504McQueen MB, Devlin B, Faraone SV, Nimgaonkar VL, Sklar P, Smoller JW, Abou Jamra R, Albus M, Bacanu SA, Baron M, Barrett TB, Berrettini W, Blacker D, Byerley W, Cichon S, Coryell W, Craddock N, Daly MJ, Depaulo JR, Edenberg HJ, Foroud T, Gill M, Gilliam TC, Hamshere M, Jones I, Jones L, Juo SH, Kelsoe JR, Lambert D, Lange C, Lerer B, Liu J, Maier W, Mackinnon JD, McInnis MG, McMahon FJ, Murphy DL, Nothen MM, Nurnberger JI, Pato CN, Pato MT, Potash JB, Propping P, Pulver AE, Rice JP, Rietschel M, Scheftner W, Schumacher J, Segurado R, Van Steen K, Xie W, Zandi PP, Laird NMAmerican journal of human geneticsCombined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. Am J Hum Genet. 2005 Oct; 77(4):582-95.Am J Hum Genet2005-08-15T00:00:002005Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q.16606913Zhu CW, Scarmeas N, Torgan R, Albert M, Brandt J, Blacker D, Sano M, Stern YNeurologyClinical features associated with costs in early AD: baseline data from the Predictors Study. Neurology. 2006 Apr 11; 66(7):1021-8.Neurology2006-04-11T00:00:002006Clinical features associated with costs in early AD: baseline data from the Predictors Study.18317242Jarvik L, LaRue A, Blacker D, Gatz M, Kawas C, McArdle JJ, Morris JC, Mortimer JA, Ringman JM, Ercoli L, Freimer N, Gokhman I, Manly JJ, Plassman BL, Rasgon N, Roberts JS, Sunderland T, Swan GE, Wolf PA, Zonderman ABAlzheimer disease and associated disordersChildren of persons with Alzheimer disease: what does the future hold? Alzheimer Dis Assoc Disord. 2008 Jan-Mar; 22(1):6-20.Alzheimer Dis Assoc Disord2008-01-01T00:00:002008Children of persons with Alzheimer disease: what does the future hold?18946219Zhu CW, Leibman C, McLaughlin T, Zbrozek AS, Scarmeas N, Albert M, Brandt J, Blacker D, Sano M, Stern YDementia and geriatric cognitive disordersPatient dependence and longitudinal changes in costs of care in Alzheimer's disease. Dement Geriatr Cogn Disord. 2008; 26(5):416-23.Dement Geriatr Cogn Disord2008-10-22T00:00:002008Patient dependence and longitudinal changes in costs of care in Alzheimer's disease.21460841Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, Evans D, Schneider JA, Carrasquillo MM, Ertekin-Taner N, Younkin SG, Cruchaga C, Kauwe JS, Nowotny P, Kramer P, Hardy J, Huentelman MJ, Myers AJ, Barmada MM, Demirci FY, Baldwin CT, Green RC, Rogaeva E, St George-Hyslop P, Arnold SE, Barber R, Beach T, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Carlson CS, Carney RM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cotman CW, Cummings JL, DeCarli C, DeKosky ST, Diaz-Arrastia R, Dick M, Dickson DW, Ellis WG, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Johnson N, Karlawish J, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Lah JJ, Levey AI, Lieberman AP, Lopez OL, Mack WJ, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Parisi JE, Perl DP, Peskind E, Petersen RC, Poon WW, Quinn JF, Rajbhandary RA, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosenberg RN, Sano M, Schneider LS, Seeley W, Shelanski ML, Slifer MA, Smith CD, Sonnen JA, Spina S, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL, Cantwell LB, Dombroski BA, Beekly D, Lunetta KL, Martin ER, Kamboh MI, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GDNature geneticsCommon variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet. 2011 May; 43(5):436-41.Nat Genet2011-04-03T00:00:002011Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.21518999Smith EE, Salat DH, Jeng J, McCreary CR, Fischl B, Schmahmann JD, Dickerson BC, Viswanathan A, Albert MS, Blacker D, Greenberg SMNeurologyCorrelations between MRI white matter lesion location and executive function and episodic memory. Neurology. 2011 Apr 26; 76(17):1492-9.Neurology2011-04-26T00:00:002011Correlations between MRI white matter lesion location and executive function and episodic memory.21951985Reiman EM, McKhann GM, Albert MS, Sperling RA, Petersen RC, Blacker DThe Journal of clinical psychiatryAlzheimer's disease: implications of the updated diagnostic and research criteria. J Clin Psychiatry. 2011 Sep; 72(9):1190-6.J Clin Psychiatry2011-09-01T00:00:002011Alzheimer's disease: implications of the updated diagnostic and research criteria.18378553Pihlajamäki M, DePeau KM, Blacker D, Sperling RAThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric PsychiatryImpaired medial temporal repetition suppression is related to failure of parietal deactivation in Alzheimer disease. Am J Geriatr Psychiatry. 2008 Apr; 16(4):283-92.Am J Geriatr Psychiatry2008-04-01T00:00:002008Impaired medial temporal repetition suppression is related to failure of parietal deactivation in Alzheimer disease.21490323Dickerson BC, Stoub TR, Shah RC, Sperling RA, Killiany RJ, Albert MS, Hyman BT, Blacker D, Detoledo-Morrell LNeurologyAlzheimer-signature MRI biomarker predicts AD dementia in cognitively normal adults. Neurology. 2011 Apr 19; 76(16):1395-402.Neurology2011-04-13T00:00:002011Alzheimer-signature MRI biomarker predicts AD dementia in cognitively normal adults.21812099Choi Y, Marchani EE, Bird TD, Steinbart EJ, Blacker D, Wijsman EMAmerican journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric GeneticsGenome scan of age-at-onset in the NIMH Alzheimer disease sample uncovers multiple loci, along with evidence of both genetic and sample heterogeneity. Am J Med Genet B Neuropsychiatr Genet. 2011 Dec; 156B(7):785-98.Am J Med Genet B Neuropsychiatr Genet2011-08-02T00:00:002011Genome scan of age-at-onset in the NIMH Alzheimer disease sample uncovers multiple loci, along with evidence of both genetic and sample heterogeneity.19204163Schjeide BM, Hooli B, Parkinson M, Hogan MF, DiVito J, Mullin K, Blacker D, Tanzi RE, Bertram LArchives of neurologyGAB2 as an Alzheimer disease susceptibility gene: follow-up of genomewide association results. Arch Neurol. 2009 Feb; 66(2):250-4.Arch Neurol2009-02-01T00:00:002009GAB2 as an Alzheimer disease susceptibility gene: follow-up of genomewide association results.8886160Blacker D, Faraone SV, Rosen AE, Guroff JJ, Adams P, Weissman MM, Gershon ESAmerican journal of medical geneticsUnipolar relatives in bipolar pedigrees: a search for elusive indicators of underlying bipolarity. Am J Med Genet. 1996 Sep 20; 67(5):445-54.Am J Med Genet1996-09-20T00:00:001996Unipolar relatives in bipolar pedigrees: a search for elusive indicators of underlying bipolarity.21425518Ganguli M, Blacker D, Blazer DG, Grant I, Jeste DV, Paulsen JS, Petersen RC, Sachdev PSThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric PsychiatryClassification of neurocognitive disorders in DSM-5: a work in progress. Am J Geriatr Psychiatry. 2011 Mar; 19(3):205-10.Am J Geriatr Psychiatry2011-03-01T00:00:002011Classification of neurocognitive disorders in DSM-5: a work in progress.9008509Blacker D, Haines JL, Rodes L, Terwedow H, Go RC, Harrell LE, Perry RT, Bassett SS, Chase G, Meyers D, Albert MS, Tanzi RNeurologyApoE-4 and age at onset of Alzheimer's disease: the NIMH genetics initiative. Neurology. 1997 Jan; 48(1):139-47.Neurology1997-01-01T00:00:001997ApoE-4 and age at onset of Alzheimer's disease: the NIMH genetics initiative.Authorship 1042835929381739Smith EE, Muzikansky A, McCreary CR, Batool S, Viswanathan A, Dickerson BC, Johnson K, Greenberg SM, Blacker DPloS oneImpaired memory is more closely associated with brain beta-amyloid than leukoaraiosis in hypertensive patients with cognitive symptoms. PLoS One. 2018; 13(1):e0191345.PLoS One2018-01-30T00:00:002018Impaired memory is more closely associated with brain beta-amyloid than leukoaraiosis in hypertensive patients with cognitive symptoms.Authorship 1000264Authorship 10078811108775Blacker DStrokeHigh rate of complete recanalization and dramatic clinical recovery during tPA infusion when continuously monitored with 2-MHz transcranial Doppler monitoring. Stroke. 2000 Dec; 31(12):3079-83.Stroke2000-12-01T00:00:002000High rate of complete recanalization and dramatic clinical recovery during tPA infusion when continuously monitored with 2-MHz transcranial Doppler monitoring.