JDM4JamesMcCullyJames Donald McCully, Ph.D.42.34022770000000-71.1058540000000051668McCully, JamesDonald617/667-0725Associate Professor of Surgerycatalyst:eCommonsLogineCommons Loginprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:address2address line 2vivo:address3address line 3vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:middleNamemiddle name or initialvivo:personInPositionpositionsvivo:phoneNumberphonePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofvivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson11515897Stadler B, Phillips J, Toyoda Y, Federman M, Levitsky S, McCully JDThe Annals of thoracic surgeryAdenosine-enhanced ischemic preconditioning modulates necrosis and apoptosis: effects of stunning and ischemia-reperfusion. Ann Thorac Surg. 2001 Aug; 72(2):555-63; discussion 563-4.Ann Thorac Surg2001-08-01T00:00:002001Adenosine-enhanced ischemic preconditioning modulates necrosis and apoptosis: effects of stunning and ischemia-reperfusion.8729056McCully JD, Lotz MM, Krukenkamp IB, Levitsky SJournal of molecular and cellular cardiologyA brief period of retrograde hyperthermic perfusion enhances myocardial protection from global ischemia: association with accumulation of Hsp 70 mRNA and protein. J Mol Cell Cardiol. 1996 Feb; 28(2):231-41.J Mol Cell Cardiol1996-02-01T00:00:001996A brief period of retrograde hyperthermic perfusion enhances myocardial protection from global ischemia: association with accumulation of Hsp 70 mRNA and protein.Authorship 10563981129588218Ramirez-Barbieri G, Moskowitzova K, Shin B, Blitzer D, Orfany A, Guariento A, Iken K, Friehs I, Zurakowski D, Del Nido PJ, McCully JDMitochondrionAlloreactivity and allorecognition of syngeneic and allogeneic mitochondria. Mitochondrion. 2019 05; 46:103-115.Mitochondrion2018-03-26T00:00:002018Alloreactivity and allorecognition of syngeneic and allogeneic mitochondria.Authorship 1064750229770298Emani SM, McCully JDTranslational pediatricsMitochondrial transplantation: applications for pediatric patients with congenital heart disease. Transl Pediatr. 2018 Apr; 7(2):169-175.Transl Pediatr2018-04-01T00:00:002018Mitochondrial transplantation: applications for pediatric patients with congenital heart disease.7575002Sasaki S, McCully JD, Palombo JD, Forse RA, LoCicero JThe Annals of thoracic surgeryLung preservation threshold in a compromised septic lung injury model. Ann Thorac Surg. 1995 Oct; 60(4):958-62; discussion 962-3.Ann Thorac Surg1995-10-01T00:00:001995Lung preservation threshold in a compromised septic lung injury model.7586446Faulk EA, McCully JD, Hadlow NC, Tsukube T, Krukenkamp IB, Federman M, Levitsky SCirculationMagnesium cardioplegia enhances mRNA levels and the maximal velocity of cytochrome oxidase I in the senescent myocardium during global ischemia. Circulation. 1995 Nov 01; 92(9 Suppl):II405-12.Circulation1995-11-01T00:00:001995Magnesium cardioplegia enhances mRNA levels and the maximal velocity of cytochrome oxidase I in the senescent myocardium during global ischemia.8158658Ataka K, Chen D, McCully J, Levitsky S, Feinberg HJournal of molecular and cellular cardiologyMagnesium cardioplegia prevents accumulation of cytosolic calcium in the ischemic myocardium. J Mol Cell Cardiol. 1993 Dec; 25(12):1387-90.J Mol Cell Cardiol1993-12-01T00:00:001993Magnesium cardioplegia prevents accumulation of cytosolic calcium in the ischemic myocardium.Authorship 1122831Authorship 114014219454556McCully JD, Bhasin MK, Daly C, Guerrero MC, Dillon S, Liberman TA, Cowan DB, Mably JD, McGowan FX, Levitsky SPhysiological genomicsTranscriptomic and proteomic analysis of global ischemia and cardioprotection in the rabbit heart. Physiol Genomics. 2009 Jul 09; 38(2):125-37.Physiol Genomics2009-05-19T00:00:002009Transcriptomic and proteomic analysis of global ischemia and cardioprotection in the rabbit heart.19632402Toumpoulis IK, Oxford JT, Cowan DB, Anagnostopoulos CE, Rokkas CK, Chamogeorgakis TP, Angouras DC, Shemin RJ, Navab M, Ericsson M, Federman M, Levitsky S, McCully JDThe Annals of thoracic surgeryDifferential expression of collagen type V and XI alpha-1 in human ascending thoracic aortic aneurysms. Ann Thorac Surg. 2009 Aug; 88(2):506-13.Ann Thorac Surg2009-08-01T00:00:002009Differential expression of collagen type V and XI alpha-1 in human ascending thoracic aortic aneurysms.Authorship 11742027944743Tsukube T, McCully JD, Faulk EA, Federman M, LoCicero J, Krukenkamp IB, Levitsky SThe Annals of thoracic surgeryMagnesium cardioplegia reduces cytosolic and nuclear calcium and DNA fragmentation in the senescent myocardium. Ann Thorac Surg. 1994 Oct; 58(4):1005-11.Ann Thorac Surg1994-10-01T00:00:001994Magnesium cardioplegia reduces cytosolic and nuclear calcium and DNA fragmentation in the senescent myocardium.7602605McCully JD, Myrmel T, Lotz MM, Krukenkamp IB, Levitsky SJournal of molecular and cellular cardiologyThe rapid expression of myocardial hsp 70 mRNA and the heat shock 70 kDa protein can be achieved after only a brief period of retrograde hyperthermic perfusion. J Mol Cell Cardiol. 1995 Mar; 27(3):873-82.J Mol Cell Cardiol1995-03-01T00:00:001995The rapid expression of myocardial hsp 70 mRNA and the heat shock 70 kDa protein can be achieved after only a brief period of retrograde hyperthermic perfusion.Authorship 11114931730391192Moskowitzova K, Shin B, Liu K, Ramirez-Barbieri G, Guariento A, Blitzer D, Thedsanamoorthy JK, Yao R, Snay ER, Inkster JAH, Orfany A, Zurakowski D, Cowan DB, Packard AB, Visner GA, Del Nido PJ, McCully JDThe Journal of heart and lung transplantation : the official publication of the International Society for Heart TransplantationMitochondrial transplantation prolongs cold ischemia time in murine heart transplantation. J Heart Lung Transplant. 2019 01; 38(1):92-99.J Heart Lung Transplant2018-09-28T00:00:002018Mitochondrial transplantation prolongs cold ischemia time in murine heart transplantation.14715509McCully JD, Wakiyama H, Hsieh YJ, Jones M, Levitsky SAmerican journal of physiology. Heart and circulatory physiologyDifferential contribution of necrosis and apoptosis in myocardial ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol. 2004 May; 286(5):H1923-35.Am J Physiol Heart Circ Physiol2004-01-08T00:00:002004Differential contribution of necrosis and apoptosis in myocardial ischemia-reperfusion injury.7544101Faulk EA, McCully JD, Tsukube T, Hadlow NC, Krukenkamp IB, Levitsky SThe Annals of thoracic surgeryMyocardial mitochondrial calcium accumulation modulates nuclear calcium accumulation and DNA fragmentation. Ann Thorac Surg. 1995 Aug; 60(2):338-44.Ann Thorac Surg1995-08-01T00:00:001995Myocardial mitochondrial calcium accumulation modulates nuclear calcium accumulation and DNA fragmentation.7675793Nanji AA, Griniuviene B, Yacoub LK, Sadrzadeh SM, Levitsky S, McCully JDProceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)Heat-shock gene expression in alcoholic liver disease in the rat is related to the severity of liver injury and lipid peroxidation. Proc Soc Exp Biol Med. 1995 Oct; 210(1):12-9.Proc Soc Exp Biol Med1995-10-01T00:00:001995Heat-shock gene expression in alcoholic liver disease in the rat is related to the severity of liver injury and lipid peroxidation.12607710McCully JD, Levitsky SThe Annals of thoracic surgeryThe mitochondrial K(ATP) channel and cardioprotection. Ann Thorac Surg. 2003 Feb; 75(2):S667-73.Ann Thorac Surg2003-02-01T00:00:002003The mitochondrial K(ATP) channel and cardioprotection.2023240McCully JD, Wang RX, Kellam B, Sole MJ, Liew CCJournal of molecular biologyIsolation and characterization of a previously unrecognized myosin heavy chain gene present in the Syrian hamster. J Mol Biol. 1991 Apr 20; 218(4):657-65.J Mol Biol1991-04-20T00:00:001991Isolation and characterization of a previously unrecognized myosin heavy chain gene present in the Syrian hamster.6190543McCully JD, Taylor PB, Morrison NLCanadian journal of physiology and pharmacologyAlterations in myocardial RNA synthesis and RNA polymerase activity during normal growth. Can J Physiol Pharmacol. 1983 Apr; 61(4):341-8.Can J Physiol Pharmacol1983-04-01T00:00:001983Alterations in myocardial RNA synthesis and RNA polymerase activity during normal growth.D015428Disorders1994760.748053Myocardial Reperfusion InjuryD006324Procedures1033550.856742Heart Arrest, InducedD015427Disorders40710250.594318Reperfusion InjuryD008928AnatomyPhysiology145235220.381918MitochondriaD008929Anatomy1422480.850013Mitochondria, HeartAnaesthesiaEmeritusMedicineRadiologySurgerySystems BiologyCardiologyGeneral MedicineBeth Israel Deaconess Medical CenterBrigham and Women's HospitalBoston Children's HospitalHarvard Medical SchoolMassachusetts General HospitalVKM1VamsiMoothaVamsi Krishna Mootha, M.D.42.36125700000000-71.0655270000000024390Mootha, VamsiProfessor of Systems BiologyDLB20DeepakBhattDeepak L. Bhatt, M.D.42.33510370000000-71.1061649000000081016Bhatt, DeepakVisiting Professor of MedicineLP39LeenaPradhan-NabzdykLeena Pradhan-Nabzdyk, Ph.D.42.34022770000000-71.1058540000000081663Pradhan-Nabzdyk, LeenaAssistant Professor of Surgery, Part-timeDZ6DavidZurakowskiDavid Zurakowski, Ph.D.42.33743600000000-71.1054470000000029952Zurakowski, DavidAssociate Professor of AnaesthesiaRD5RaphaelDolinRaphael Dolin, M.D.42.34022770000000-71.1058540000000035497Dolin, RaphaelMaxwell Finland Professor of Medicine (Microbiology and Molecular Genetics)AEV7AmyVinsonAmy Elizabeth Vinson, M.D.42.34022770000000-71.1058540000000085564Vinson, AmyAssistant Professor of AnaesthesiaSE45SitaramEmaniSitaram Emani, M.D.42.33743600000000-71.105447000000008962Emani, SitaramAssociate Professor of SurgeryPJD2PedroDel NidoPedro J. Del Nido, M.D.42.33743600000000-71.1054470000000065742Del Nido, PedroWilliam E. Ladd Professor of Child Surgery11100selected publications5.329170.00447302366research areas7.020890.049667529coauthor of58.99114.808960similar toHSK6HansKimHans Sung Kim, M.D.42.34022770000000-71.1058540000000017326Kim, HansAssistant Professor of MedicineSL8SidneyLevitskySidney Levitsky, M.D.42.33852520000000-71.1092863000000053275Levitsky, SidneyCheever Professor of Surgery, EmeritusEB3EugeneBraunwaldEugene Braunwald, M.D.42.33864350000000-71.1068662000000062123Braunwald, EugeneHersey Distinguished Professor of the Theory and Practice of PhysicRS222RajaShaikhRaja Shaikh, M.D.42.34022770000000-71.1058540000000090854Shaikh, RajaAssistant Professor of RadiologyAuthorship 1366641Authorship 11765711131353269Orfany A, Arriola CG, Doulamis IP, Guariento A, Ramirez-Barbieri G, Moskowitzova K, Shin B, Blitzer D, Rogers C, Del Nido PJ, McCully JDJournal of vascular surgeryMitochondrial transplantation ameliorates acute limb ischemia. J Vasc Surg. 2020 03; 71(3):1014-1026.J Vasc Surg2019-07-26T00:00:002019Mitochondrial transplantation ameliorates acute limb ischemia.Authorship 1181850931421103Blitzer D, Guariento A, Doulamis IP, Shin B, Moskowitzova K, Barbieri GR, Orfany A, Del Nido PJ, McCully JDThe Annals of thoracic surgeryDelayed Transplantation of Autologous Mitochondria for Cardioprotection in a Porcine Model. Ann Thorac Surg. 2020 03; 109(3):711-719.Ann Thorac Surg2019-08-14T00:00:002019Delayed Transplantation of Autologous Mitochondria for Cardioprotection in a Porcine Model.Authorship 1449981Authorship 11941441131564546Guariento A, Blitzer D, Doulamis I, Shin B, Moskowitzova K, Orfany A, Ramirez-Barbieri G, Staffa SJ, Zurakowski D, Del Nido PJ, McCully JDThe Journal of thoracic and cardiovascular surgeryPreischemic autologous mitochondrial transplantation by intracoronary injection for myocardial protection. J Thorac Cardiovasc Surg. 2020 Aug; 160(2):e15-e29.J Thorac Cardiovasc Surg2019-08-28T00:00:002019Preischemic autologous mitochondrial transplantation by intracoronary injection for myocardial protection.Authorship 1122951Authorship 12031241831693391Moskowitzova K, Orfany A, Liu K, Ramirez-Barbieri G, Thedsanamoorthy JK, Yao R, Guariento A, Doulamis IP, Blitzer D, Shin B, Snay ER, Inkster JAH, Iken K, Packard AB, Cowan DB, Visner GA, Del Nido PJ, McCully JDAmerican journal of physiology. Lung cellular and molecular physiologyMitochondrial transplantation enhances murine lung viability and recovery after ischemia-reperfusion injury. Am J Physiol Lung Cell Mol Physiol. 2020 01 01; 318(1):L78-L88.Am J Physiol Lung Cell Mol Physiol2019-11-06T00:00:002019Mitochondrial transplantation enhances murine lung viability and recovery after ischemia-reperfusion injury.true1Assistant Professor of Surgery, Part-timeAssistant Professor of Surgery, Part-timetrue1Assistant Professor of MedicineAssistant Professor of MedicineAuthorship 1245488Authorship 1208719831782771Doulamis IP, Guariento A, Duignan T, Orfany A, Kido T, Zurakowski D, Del Nido PJ, McCully JDEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic SurgeryMitochondrial transplantation for myocardial protection in diabetic hearts. Eur J Cardiothorac Surg. 2020 05 01; 57(5):836-845.Eur J Cardiothorac Surg2020-05-01T00:00:002020Mitochondrial transplantation for myocardial protection in diabetic hearts.Authorship 12173311731909298Shin B, Saeed MY, Esch JJ, Guariento A, Blitzer D, Moskowitzova K, Ramirez-Barbieri G, Orfany A, Thedsanamoorthy JK, Cowan DB, Inkster JA, Snay ER, Staffa SJ, Packard AB, Zurakowski D, Del Nido PJ, McCully JDJACC. Basic to translational scienceA Novel Biological Strategy for Myocardial Protection by Intracoronary Delivery of Mitochondria: Safety and Efficacy. JACC Basic Transl Sci. 2019 Dec; 4(8):871-888.JACC Basic Transl Sci2019-12-23T00:00:002019A Novel Biological Strategy for Myocardial Protection by Intracoronary Delivery of Mitochondria: Safety and Efficacy.Authorship 1234146132140627McCully JD, Emani SM, Del Nido PJJACC. Basic to translational scienceReply: Intracoronary Delivery of Mitochondria to Prevent Ischemia-Reperfusion Injury: Challenging Pathway From Bench to Bedside. JACC Basic Transl Sci. 2020 Feb; 5(2):209.JACC Basic Transl Sci2020-02-24T00:00:002020Reply: Intracoronary Delivery of Mitochondria to Prevent Ischemia-Reperfusion Injury: Challenging Pathway From Bench to Bedside.Authorship 1238885132271682McCully JD, Emani SM, Del Nido PJCirculation researchLetter by McCully et al Regarding Article, "Mitochondria Do Not Survive Calcium Overload". Circ Res. 2020 04 10; 126(8):e56-e57.Circ Res2020-04-09T00:00:002020Letter by McCully et al Regarding Article, "Mitochondria Do Not Survive Calcium Overload".Authorship 12506181132466053Guariento A, Doulamis IP, Duignan T, Kido T, Regan WL, Saeed M, Hoganson DM, Emani SM, Matte GS, Del Nido PJ, McCully JDThe Journal of heart and lung transplantation : the official publication of the International Society for Heart TransplantationMitochondrial Transplantation for Myocardial Protection in Ex-Situ Perfused Hearts Donated after Cardio-Circulatory Death. J Heart Lung Transplant. 2020 Apr; 39(4S):S87.J Heart Lung Transplant2020-03-30T00:00:002020Mitochondrial Transplantation for Myocardial Protection in Ex-Situ Perfused Hearts Donated after Cardio-Circulatory Death.Authorship 126754412Authorship 12681891932686525Doulamis IP, Guariento A, Duignan T, Kido T, Orfany A, Saeed MY, Weixler VH, Blitzer D, Shin B, Snay ER, Inkster JA, Packard AB, Zurakowski D, Rousselle T, Bajwa A, Parikh SM, Stillman IE, Del Nido PJ, McCully JDAmerican journal of physiology. Renal physiologyMitochondrial transplantation by intra-arterial injection for acute kidney injury. Am J Physiol Renal Physiol. 2020 09 01; 319(3):F403-F413.Am J Physiol Renal Physiol2020-07-20T00:00:002020Mitochondrial transplantation by intra-arterial injection for acute kidney injury.32703639Guariento A, Doulamis IP, Duignan T, Kido T, Regan WL, Saeed MY, Hoganson DM, Emani SM, Fynn-Thompson F, Matte GS, Del Nido PJ, McCully JDThe Journal of heart and lung transplantation : the official publication of the International Society for Heart TransplantationMitochondrial transplantation for myocardial protection in ex-situ?perfused hearts donated after circulatory death. J Heart Lung Transplant. 2020 11; 39(11):1279-1288.J Heart Lung Transplant2020-06-29T00:00:002020Mitochondrial transplantation for myocardial protection in ex-situ?perfused hearts donated after circulatory death.Authorship 12840688Authorship 1284632132919774Weixler V, Lapusca R, Grangl G, Guariento A, Saeed MY, Cowan DB, Del Nido PJ, McCully JD, Friehs IThe Journal of thoracic and cardiovascular surgeryAutogenous mitochondria transplantation for treatment of right heart failure. J Thorac Cardiovasc Surg. 2021 07; 162(1):e111-e121.J Thorac Cardiovasc Surg2020-08-10T00:00:002020Autogenous mitochondria transplantation for treatment of right heart failure.32919766McCully JD, Doulamis IPThe Journal of thoracic and cardiovascular surgeryCommentary: Independent, additive or linked: A novel therapeutic option for the treatment of pulmonary hypertension may involve more than one mechanism. J Thorac Cardiovasc Surg. 2022 05; 163(5):e375-e376.J Thorac Cardiovasc Surg2020-08-20T00:00:002020Commentary: Independent, additive or linked: A novel therapeutic option for the treatment of pulmonary hypertension may involve more than one mechanism.33343033Duignan T, Guariento A, Doulamis IP, Kido T, Regan WL, Saeed M, Hoganson DM, Emani SM, Del Nido PJ, McCully JD, Matte GSThe journal of extra-corporeal technologyA Multi-Mode System for Myocardial Functional and Physiological Assessment during Ex Situ Heart Perfusion. J Extra Corpor Technol. 2020 Dec; 52(4):303-313.J Extra Corpor Technol2020-12-01T00:00:002020A Multi-Mode System for Myocardial Functional and Physiological Assessment during Ex Situ Heart Perfusion.33349443Guariento A, Piekarski BL, Doulamis IP, Blitzer D, Ferraro AM, Harrild DM, Zurakowski D, Del Nido PJ, McCully JD, Emani SMThe Journal of thoracic and cardiovascular surgeryAutologous mitochondrial transplantation for cardiogenic shock in pediatric patients following ischemia-reperfusion injury. J Thorac Cardiovasc Surg. 2021 Sep; 162(3):992-1001.J Thorac Cardiovasc Surg2020-12-01T00:00:002020Autologous mitochondrial transplantation for cardiogenic shock in pediatric patients following ischemia-reperfusion injury.Authorship 13132999Authorship 13112321033616119Doulamis IP, Guariento A, Saeed MY, Nomoto RS, Duignan T, Del Nido PJ, McCully JDJournal of visualized experiments : JoVEA Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion. J Vis Exp. 2021 02 02; (168).J Vis Exp2021-02-02T00:00:002021A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion.Authorship 13332407Authorship 16078813Authorship 1482001Authorship 1361100234080142Doulamis IP, McCully JDMethods in molecular biology (Clifton, N.J.)Mitochondrial Transplantation for Ischemia Reperfusion Injury. Methods Mol Biol. 2021; 2277:15-37.Methods Mol Biol2021-01-01T00:00:002021Mitochondrial Transplantation for Ischemia Reperfusion Injury.Authorship 2081461Authorship 1438108135217248McCully JD, Del Nido PJ, Emani SMMitochondrionMitochondrial transplantation for organ rescue. Mitochondrion. 2022 05; 64:27-33.Mitochondrion2022-02-22T00:00:002022Mitochondrial transplantation for organ rescue.Authorship 336604435926043Wyant GA, Yu W, Doulamis IP, Nomoto RS, Saeed MY, Duignan T, McCully JD, Kaelin WGScience (New York, N.Y.)Mitochondrial remodeling and ischemic protection by G protein-coupled receptor 35 agonists. Science. 2022 08 05; 377(6606):621-629.Science2022-08-04T00:00:002022Mitochondrial remodeling and ischemic protection by G protein-coupled receptor 35 agonists.Authorship 14803687Authorship 1512009836543810Doulamis IP, Nomoto RS, Tzani A, Hong X, Duignan T, Celik A, Del Nido PJ, McCully JDScientific reportsTranscriptomic and proteomic pathways of diabetic and non-diabetic mitochondrial transplantation. Sci Rep. 2022 Dec 21; 12(1):22101.Sci Rep2022-12-21T00:00:002022Transcriptomic and proteomic pathways of diabetic and non-diabetic mitochondrial transplantation.Authorship 1759573Authorship 1534337536948134Celik A, Orfany A, Dearling J, Del Nido PJ, McCully JD, Bakar-Ates FBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieMitochondrial transplantation: Effects on chemotherapy in prostate and ovarian cancer cells in vitro and in vivo. Biomed Pharmacother. 2023 May; 161:114524.Biomed Pharmacother2023-03-20T00:00:002023Mitochondrial transplantation: Effects on chemotherapy in prostate and ovarian cancer cells in vitro and in vivo.Authorship 4830822Authorship 2046721Authorship 155456717Authorship 15653691037211245Alemany VS, Nomoto R, Saeed MY, Celik A, Regan WL, Matte GS, Recco DP, Emani SM, Del Nido PJ, McCully JDThe Journal of thoracic and cardiovascular surgeryMitochondrial transplantation preserves myocardial function and viability in pediatric and neonatal pig hearts donated after circulatory death. J Thorac Cardiovasc Surg. 2024 Jan; 167(1):e6-e21.J Thorac Cardiovasc Surg2023-05-20T00:00:002023Mitochondrial transplantation preserves myocardial function and viability in pediatric and neonatal pig hearts donated after circulatory death.37450698Rossi A, Asthana A, Riganti C, Sedrakyan S, Byers LN, Robertson J, Senger RS, Montali F, Grange C, Dalmasso A, Porporato PE, Palles C, Thornton ME, Da Sacco S, Perin L, Ahn B, McCully J, Orlando G, Bussolati BAnnals of surgeryMitochondria Transplantation Mitigates Damage in an In Vitro Model of Renal Tubular Injury and in an Ex Vivo Model of DCD Renal Transplantation. Ann Surg. 2023 12 01; 278(6):e1313-e1326.Ann Surg2023-07-14T00:00:002023Mitochondria Transplantation Mitigates Damage in an In Vitro Model of Renal Tubular Injury and in an Ex Vivo Model of DCD Renal Transplantation.Authorship 3837032true1Hersey Distinguished Professor of the Theory and Practice of PhysicHersey Distinguished Professor of the Theory and Practice of Physictrue1Clinical Fellow in SurgeryClinical Fellow in Surgerytrue1Visiting Professor of MedicineVisiting Professor of Medicinetrue1Maxwell Finland Professor of Medicine (Microbiology and Molecular Genetics)Maxwell Finland Professor of Medicine (Microbiology and Molecular Genetics)Authorship 4264175Authorship 1607833537982519Alemany VS, Recco DP, Emani SM, Del Nido PJ, McCully JDJournal of visualized experiments : JoVEModel of Ischemia and Reperfusion Injury in Rabbits. J Vis Exp. 2023 Nov 03; (201).J Vis Exp2023-11-03T00:00:002023Model of Ischemia and Reperfusion Injury in Rabbits.Authorship 5286471Authorship 1617820138162128McCully JD, Del Nido PJ, Emani SMFrontiers in cardiovascular medicineMitochondrial transplantation: the advance to therapeutic application and molecular modulation. Front Cardiovasc Med. 2023; 10:1268814.Front Cardiovasc Med2023-12-15T00:00:002023Mitochondrial transplantation: the advance to therapeutic application and molecular modulation.true1Professor of Systems BiologyProfessor of Systems Biologytrue1Cheever Professor of Surgery, EmeritusCheever Professor of Surgery, Emeritustrue1Associate Professor of AnaesthesiaAssociate Professor of Anaesthesiatrue1Associate Professor of SurgeryAssociate Professor of Surgerytrue1Assistant Professor of RadiologyAssistant Professor of Radiologytrue1William E. Ladd Professor of Child SurgeryWilliam E. Ladd Professor of Child Surgerytrue1Assistant Professor of AnaesthesiaAssistant Professor of Anaesthesiatrue1Associate Professor of SurgeryAssociate Professor of SurgeryAuthorship 1646356Authorship 471451Authorship 365041Authorship 2267034Authorship 2363327Authorship 6915601224231657Black KM, Masuzawa A, Hagberg RC, Khabbaz KR, Trovato ME, Rettagliati VM, Bhasin MK, Dillon ST, Libermann TA, Toumpoulis IK, Levitsky S, McCully JDJournal of the American Heart AssociationPreliminary biomarkers for identification of human ascending thoracic aortic aneurysm. J Am Heart Assoc. 2013 Nov 14; 2(6):e000138.J Am Heart Assoc2013-11-14T00:00:002013Preliminary biomarkers for identification of human ascending thoracic aortic aneurysm.Authorship 2329642Authorship 2564465Authorship 671522Authorship 1709496Authorship 3640143Authorship 4043025Authorship 758622625225817Preble JM, Pacak CA, Kondo H, MacKay AA, Cowan DB, McCully JDJournal of visualized experiments : JoVERapid isolation and purification of mitochondria for transplantation by tissue dissociation and differential filtration. J Vis Exp. 2014 Sep 06; (91):e51682.J Vis Exp2014-09-06T00:00:002014Rapid isolation and purification of mitochondria for transplantation by tissue dissociation and differential filtration.25250622Pacak CA, Hammer PE, MacKay AA, Dowd RP, Wang KR, Masuzawa A, Sill B, McCully JD, Cowan DBPloS oneSuperparamagnetic iron oxide nanoparticles function as a long-term, multi-modal imaging label for non-invasive tracking of implanted progenitor cells. PLoS One. 2014; 9(9):e108695.PLoS One2014-09-24T00:00:002014Superparamagnetic iron oxide nanoparticles function as a long-term, multi-modal imaging label for non-invasive tracking of implanted progenitor cells.Authorship 7598228Authorship 370181Authorship 422152Authorship 518438125862247Pacak CA, Preble JM, Kondo H, Seibel P, Levitsky S, Del Nido PJ, Cowan DB, McCully JDBiology openActin-dependent mitochondrial internalization in cardiomyocytes: evidence for rescue of mitochondrial function. Biol Open. 2015 Apr 10; 4(5):622-6.Biol Open2015-04-10T00:00:002015Actin-dependent mitochondrial internalization in cardiomyocytes: evidence for rescue of mitochondrial function.Authorship 886546Authorship 4252601Authorship 3360181Authorship 4660376Authorship 5419721Authorship 2169792Authorship 6863511Authorship 999631Authorship 3840971Authorship 2684361Authorship 3439411Authorship 4677331Authorship 3516202Authorship 3640591Authorship 3841915Authorship 2708291Authorship 2579503Authorship 8007218Authorship 918743Authorship 2841572Authorship 3201003Authorship 3849106Authorship 4715753Authorship 3171485Authorship 850411326463990Bautista-Hernandez V, Karamanlidis G, McCully JD, Del Nido PJCurrent vascular pharmacologyCellular and Molecular Mechanisms of Low Cardiac Output Syndrome after Pediatric Cardiac Surgery. Curr Vasc Pharmacol. 2016; 14(1):5-13.Curr Vasc Pharmacol2016-01-01T00:00:002016Cellular and Molecular Mechanisms of Low Cardiac Output Syndrome after Pediatric Cardiac Surgery.Authorship 546675127130633McCully JD, Levitsky S, Del Nido PJ, Cowan DBClinical and translational medicineMitochondrial transplantation for therapeutic use. Clin Transl Med. 2016 Mar; 5(1):16.Clin Transl Med2016-04-29T00:00:002016Mitochondrial transplantation for therapeutic use.Authorship 88008212Assistant Professor1Associate Professor6Fellow or Post Doc0Full ProfessorAuthorship 924961327500955Cowan DB, Yao R, Akurathi V, Snay ER, Thedsanamoorthy JK, Zurakowski D, Ericsson M, Friehs I, Wu Y, Levitsky S, Del Nido PJ, Packard AB, McCully JDPloS oneIntracoronary Delivery of Mitochondria to the Ischemic Heart for Cardioprotection. PLoS One. 2016; 11(8):e0160889.PLoS One2016-08-08T00:00:002016Intracoronary Delivery of Mitochondria to the Ischemic Heart for Cardioprotection.Authorship 89730413Authorship 50132032001-07-31MCCULLY, JAMES D1998-08-01MITOCHONDRIAL DNA DELETIONS IN CARDIAC SURGERYR01HL0595422011-08-31LEVITSKY, SIDNEY1983-07-01Myocardial Protection: Reperfusion Injury AmeliorationR01HL0290772014-06-30MCCULLY, JAMES D2010-07-01Autogeneic Mitochondria: Surgical CardioprotectionR01HL103642Co-Principal InvestigatorPrincipal InvestigatorPrincipal InvestigatorAuthorship 3669815Authorship 9411801427938904Kaza AK, Wamala I, Friehs I, Kuebler JD, Rathod RH, Berra I, Ericsson M, Yao R, Thedsanamoorthy JK, Zurakowski D, Levitsky S, Del Nido PJ, Cowan DB, McCully JDThe Journal of thoracic and cardiovascular surgeryMyocardial rescue with autologous mitochondrial transplantation in a porcine model of ischemia/reperfusion. J Thorac Cardiovasc Surg. 2017 04; 153(4):934-943.J Thorac Cardiovasc Surg2016-11-15T00:00:002016Myocardial rescue with autologous mitochondrial transplantation in a porcine model of ischemia/reperfusion.Authorship 47196018906174McCully JD, Levitsky SAnnals of the New York Academy of SciencesMyocardial protection in the elderly. Biology of the senescent heart. Ann N Y Acad Sci. 1996 Sep 30; 793:305-18.Ann N Y Acad Sci1996-09-30T00:00:001996Myocardial protection in the elderly. Biology of the senescent heart.KM328KamilaMoskowitzovaKamila Moskowitzova, M.D.156493Moskowitzova, KamilaClinical Fellow in Surgery9671910McCully JD, Uematsu M, Parker RA, Levitsky SThe Journal of thoracic and cardiovascular surgeryAdenosine-enhanced ischemic preconditioning provides enhanced postischemic recovery and limitation of infarct size in the rabbit heart. J Thorac Cardiovasc Surg. 1998 Jul; 116(1):154-62.J Thorac Cardiovasc Surg1998-07-01T00:00:001998Adenosine-enhanced ischemic preconditioning provides enhanced postischemic recovery and limitation of infarct size in the rabbit heart.9725373Uematsu M, Gaudette GR, Laurikka JO, Levitsky S, McCully JDThe Annals of thoracic surgeryAdenosine-enhanced ischemic preconditioning decreases infarct in the regional ischemic sheep heart. Ann Thorac Surg. 1998 Aug; 66(2):382-7.Ann Thorac Surg1998-08-01T00:00:001998Adenosine-enhanced ischemic preconditioning decreases infarct in the regional ischemic sheep heart.Authorship 968879528283239Emani SM, Piekarski BL, Harrild D, Del Nido PJ, McCully JDThe Journal of thoracic and cardiovascular surgeryAutologous mitochondrial transplantation for dysfunction after ischemia-reperfusion injury. J Thorac Cardiovasc Surg. 2017 07; 154(1):286-289.J Thorac Cardiovasc Surg2017-02-15T00:00:002017Autologous mitochondrial transplantation for dysfunction after ischemia-reperfusion injury.9386104Matsuda H, McCully JD, Levitsky SCirculationDevelopmental differences in cytosolic calcium accumulation associated with global ischemia: evidence for differential intracellular calcium channel receptor activity. Circulation. 1997 Nov 04; 96(9 Suppl):II-233-8; discussion II-238-9.Circulation1997-11-04T00:00:001997Developmental differences in cytosolic calcium accumulation associated with global ischemia: evidence for differential intracellular calcium channel receptor activity.2464996McCully JD, Liew CCThe Biochemical journalRNA transcription in myocardial-cell nuclei during postnatal development. A study establishing an assay system for transcription in vitro. Biochem J. 1988 Dec 01; 256(2):441-5.Biochem J1988-12-01T00:00:001988RNA transcription in myocardial-cell nuclei during postnatal development. A study establishing an assay system for transcription in vitro.28342934McCully JD, Cowan DB, Emani SM, Del Nido PJMitochondrionMitochondrial transplantation: From animal models to clinical use in humans. Mitochondrion. 2017 05; 34:127-134.Mitochondrion2017-03-22T00:00:002017Mitochondrial transplantation: From animal models to clinical use in humans.12400769Bianchi C, Wakiyama H, Faro R, Khan T, McCully JD, Levitsky S, Szabó C, Sellke FWThe Annals of thoracic surgeryA novel peroxynitrite decomposer catalyst (FP-15) reduces myocardial infarct size in an in vivo peroxynitrite decomposer and acute ischemia-reperfusion in pigs. Ann Thorac Surg. 2002 Oct; 74(4):1201-7.Ann Thorac Surg2002-10-01T00:00:002002A novel peroxynitrite decomposer catalyst (FP-15) reduces myocardial infarct size in an in vivo peroxynitrite decomposer and acute ischemia-reperfusion in pigs.Authorship 973837116798201McCully JD, Toyoda Y, Wakiyama H, Rousou AJ, Parker RA, Levitsky SThe Annals of thoracic surgeryAge- and gender-related differences in ischemia/reperfusion injury and cardioprotection: effects of diazoxide. Ann Thorac Surg. 2006 Jul; 82(1):117-23.Ann Thorac Surg2006-07-01T00:00:002006Age- and gender-related differences in ischemia/reperfusion injury and cardioprotection: effects of diazoxide.9368237McCully JD, Levitsky SMagnesium researchMechanisms of in vitro cardioprotective action of magnesium on the aging myocardium. Magnes Res. 1997 Jun; 10(2):157-68.Magnes Res1997-06-01T00:00:001997Mechanisms of in vitro cardioprotective action of magnesium on the aging myocardium.11087223Toyoda Y, Friehs I, Parker RA, Levitsky S, McCully JDAmerican journal of physiology. Heart and circulatory physiologyDifferential role of sarcolemmal and mitochondrial K(ATP) channels in adenosine-enhanced ischemic preconditioning. Am J Physiol Heart Circ Physiol. 2000 Dec; 279(6):H2694-703.Am J Physiol Heart Circ Physiol2000-12-01T00:00:002000Differential role of sarcolemmal and mitochondrial K(ATP) channels in adenosine-enhanced ischemic preconditioning.9249517Tsukube T, McCully JD, Metz KR, Cook CU, Levitsky SThe American journal of physiologyAmelioration of ischemic calcium overload correlates with high-energy phosphates in senescent myocardium. Am J Physiol. 1997 Jul; 273(1 Pt 2):H418-25.Am J Physiol1997-07-01T00:00:001997Amelioration of ischemic calcium overload correlates with high-energy phosphates in senescent myocardium.15242834Rousou AJ, Ericsson M, Federman M, Levitsky S, McCully JDAmerican journal of physiology. Heart and circulatory physiologyOpening of mitochondrial KATP channels enhances cardioprotection through the modulation of mitochondrial matrix volume, calcium accumulation, and respiration. Am J Physiol Heart Circ Physiol. 2004 Nov; 287(5):H1967-76.Am J Physiol Heart Circ Physiol2004-07-08T00:00:002004Opening of mitochondrial KATP channels enhances cardioprotection through the modulation of mitochondrial matrix volume, calcium accumulation, and respiration.10215213McCully JD, Uematsu M, Levitsky SThe Annals of thoracic surgeryAdenosine-enhanced ischemic preconditioning provides myocardial protection equal to that of cold blood cardioplegia. Ann Thorac Surg. 1999 Mar; 67(3):699-704.Ann Thorac Surg1999-03-01T00:00:001999Adenosine-enhanced ischemic preconditioning provides myocardial protection equal to that of cold blood cardioplegia.10194035Sasaki S, Yasuda K, McCully JD, LoCicero JThe Journal of heart and lung transplantation : the official publication of the International Society for Heart TransplantationCalcium channel blocker enhances lung preservation. J Heart Lung Transplant. 1999 Feb; 18(2):127-32.J Heart Lung Transplant1999-02-01T00:00:001999Calcium channel blocker enhances lung preservation.10639250Krukenkamp IB, McCully J, Levitsky SJournal of thrombosis and thrombolysis"Reperfusion Injury" and Myocardial Protection by Cardioplegia: An Opinion. J Thromb Thrombolysis. 1997 Jan; 4(1):131-132.J Thromb Thrombolysis1997-01-01T00:00:001997"Reperfusion Injury" and Myocardial Protection by Cardioplegia: An Opinion.11565667Toyoda Y, Khan S, Chen W, Parker RA, Levitsky S, McCully JDThe Annals of thoracic surgeryEffects of NHE-1 inhibition on cardioprotection and impact on protection by K/Mg cardioplegia. Ann Thorac Surg. 2001 Sep; 72(3):836-43; discussion 843-4.Ann Thorac Surg2001-09-01T00:00:002001Effects of NHE-1 inhibition on cardioprotection and impact on protection by K/Mg cardioplegia.11845877Faro R, Toyoda Y, McCully JD, Jagtap P, Szabo E, Virag L, Bianchi C, Levitsky S, Szabo C, Sellke FWThe Annals of thoracic surgeryMyocardial protection by PJ34, a novel potent poly (ADP-ribose) synthetase inhibitor. Ann Thorac Surg. 2002 Feb; 73(2):575-81.Ann Thorac Surg2002-02-01T00:00:002002Myocardial protection by PJ34, a novel potent poly (ADP-ribose) synthetase inhibitor.1710470McCully JD, Mably JD, Sole MJ, Liew CCBiochemistry and cell biology = Biochimie et biologie cellulaireRNA transcription and translation in the hearts of normal and cardiomyopathic Syrian hamsters. Biochem Cell Biol. 1991 Jan; 69(1):88-92.Biochem Cell Biol1991-01-01T00:00:001991RNA transcription and translation in the hearts of normal and cardiomyopathic Syrian hamsters.12643408McCully JD, Wakiyama H, Cowan DB, Federman M, Parker RA, Levitsky SThe Annals of thoracic surgeryDiazoxide amelioration of myocardial injury and mitochondrial damage during cardiac surgery. Ann Thorac Surg. 2002 Dec; 74(6):2138-45; discussion 2146.Ann Thorac Surg2002-12-01T00:00:002002Diazoxide amelioration of myocardial injury and mitochondrial damage during cardiac surgery.10415541McCully JD, Levitsky SAnnals of the New York Academy of SciencesAlternatives for myocardial protection: adenosine-enhanced ischemic preconditioning. Ann N Y Acad Sci. 1999 Jun 30; 874:295-305.Ann N Y Acad Sci1999-06-30T00:00:001999Alternatives for myocardial protection: adenosine-enhanced ischemic preconditioning.11082409Toyoda Y, Di Gregorio V, Parker RA, Levitsky S, McCully JDCirculationAnti-stunning and anti-infarct effects of adenosine-enhanced ischemic preconditioning. Circulation. 2000 Nov 07; 102(19 Suppl 3):III326-31.Circulation2000-11-07T00:00:002000Anti-stunning and anti-infarct effects of adenosine-enhanced ischemic preconditioning.300 Longwood AveChildren's HospitalCardiac Surgery, Enders 361.2300 Longwood AveBoston02115MAAuthorship 986193528551809Shin B, Cowan DB, Emani SM, Del Nido PJ, McCully JDAdvances in experimental medicine and biologyMitochondrial Transplantation in Myocardial Ischemia and Reperfusion Injury. Adv Exp Med Biol. 2017; 982:595-619.Adv Exp Med Biol2017-01-01T00:00:002017Mitochondrial Transplantation in Myocardial Ischemia and Reperfusion Injury.17888982Hsieh YJ, Wakiyama H, Levitsky S, McCully JDThe Annals of thoracic surgeryCardioplegia and diazoxide modulate STAT3 activation and DNA binding. Ann Thorac Surg. 2007 Oct; 84(4):1272-8.Ann Thorac Surg2007-10-01T00:00:002007Cardioplegia and diazoxide modulate STAT3 activation and DNA binding.11199314Sasaki S, Yasuda K, McCully JD, Palombo JD, LoCicero JASAIO journal (American Society for Artificial Internal Organs : 1992)Perfusion with lipopolysaccharide negative blood eliminates lipopolysaccharide induced lung injury. ASAIO J. 2001 Jan-Feb; 47(1):45-9.ASAIO J2001-01-01T00:00:002001Perfusion with lipopolysaccharide negative blood eliminates lipopolysaccharide induced lung injury.9930490McCully JD, Uematsu M, Parker RA, Levitsky SThe Annals of thoracic surgeryAdenosine-enhanced ischemic preconditioning provides enhanced cardioprotection in the aged heart. Ann Thorac Surg. 1998 Dec; 66(6):2037-43.Ann Thorac Surg1998-12-01T00:00:001998Adenosine-enhanced ischemic preconditioning provides enhanced cardioprotection in the aged heart.22968637Black KM, Barnett RJ, Bhasin MK, Daly C, Dillon ST, Libermann TA, Levitsky S, McCully JDPhysiological genomicsMicroarray and proteomic analysis of the cardioprotective effects of cold blood cardioplegia in the mature and aged male and female. Physiol Genomics. 2012 Nov 01; 44(21):1027-41.Physiol Genomics2012-09-11T00:00:002012Microarray and proteomic analysis of the cardioprotective effects of cold blood cardioplegia in the mature and aged male and female.2831916McCully JD, Jandreski MA, Liew J, Sole MJ, Liew CCBiochemistry and cell biology = Biochimie et biologie cellulaireConstruction of cosmid genomic libraries for the normal and myopathic Syrian hamsters. Biochem Cell Biol. 1987 Nov; 65(11):997-1000.Biochem Cell Biol1987-11-01T00:00:001987Construction of cosmid genomic libraries for the normal and myopathic Syrian hamsters.7776673Sasaki S, McCully JD, Alessandrini F, LoCicero JThe Journal of thoracic and cardiovascular surgeryImpact of initial flush potassium concentration on the adequacy of lung preservation. J Thorac Cardiovasc Surg. 1995 Jun; 109(6):1090-5; discussion 1095-6.J Thorac Cardiovasc Surg1995-06-01T00:00:001995Impact of initial flush potassium concentration on the adequacy of lung preservation.10194037Sasaki S, Yasuda K, McCully JD, LoCicero JThe Journal of heart and lung transplantation : the official publication of the International Society for Heart TransplantationDoes PGE1 attenuate potassium-induced vasoconstriction in initial pulmonary artery flush on lung preservation? J Heart Lung Transplant. 1999 Feb; 18(2):139-42.J Heart Lung Transplant1999-02-01T00:00:001999Does PGE1 attenuate potassium-induced vasoconstriction in initial pulmonary artery flush on lung preservation?Authorship 1012929128935303McCully JDThe Annals of thoracic surgeryInvited Commentary. Ann Thorac Surg. 2017 10; 104(4):1304-1305.Ann Thorac Surg2017-10-01T00:00:002017Invited Commentary.7955269Myrmel T, McCully JD, Malikin L, Krukenkamp IB, Levitsky SCirculationHeat-shock protein 70 mRNA is induced by anaerobic metabolism in rat hearts. Circulation. 1994 Nov; 90(5 Pt 2):II299-305.Circulation1994-11-01T00:00:001994Heat-shock protein 70 mRNA is induced by anaerobic metabolism in rat hearts.11158956McCully JD, Toyoda Y, Uematsu M, Stewart RD, Levitsky SAmerican journal of physiology. Heart and circulatory physiologyAdenosine-enhanced ischemic preconditioning: adenosine receptor involvement during ischemia and reperfusion. Am J Physiol Heart Circ Physiol. 2001 Feb; 280(2):H591-602.Am J Physiol Heart Circ Physiol2001-02-01T00:00:002001Adenosine-enhanced ischemic preconditioning: adenosine receptor involvement during ischemia and reperfusion.11888758Wakiyama H, Cowan DB, Toyoda Y, Federman M, Levitsky S, McCully JDEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic SurgerySelective opening of mitochondrial ATP-sensitive potassium channels during surgically induced myocardial ischemia decreases necrosis and apoptosis. Eur J Cardiothorac Surg. 2002 Mar; 21(3):424-33.Eur J Cardiothorac Surg2002-03-01T00:00:002002Selective opening of mitochondrial ATP-sensitive potassium channels during surgically induced myocardial ischemia decreases necrosis and apoptosis.11308175Toyoda Y, Levitsky S, McCully JDThe Annals of thoracic surgeryOpening of mitochondrial ATP-sensitive potassium channels enhances cardioplegic protection. Ann Thorac Surg. 2001 Apr; 71(4):1281-8; discussion 1288-9.Ann Thorac Surg2001-04-01T00:00:002001Opening of mitochondrial ATP-sensitive potassium channels enhances cardioplegic protection.12167779McCully JDThe Journal of thoracic and cardiovascular surgeryOxygenated multidose delivery of crystalloid esmolol cardioplegia as an alternative to high potassium cardioplegia. J Thorac Cardiovasc Surg. 2002 Aug; 124(2):219-20.J Thorac Cardiovasc Surg2002-08-01T00:00:002002Oxygenated multidose delivery of crystalloid esmolol cardioplegia as an alternative to high potassium cardioplegia.23355340Masuzawa A, Black KM, Pacak CA, Ericsson M, Barnett RJ, Drumm C, Seth P, Bloch DB, Levitsky S, Cowan DB, McCully JDAmerican journal of physiology. Heart and circulatory physiologyTransplantation of autologously derived mitochondria protects the heart from ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol. 2013 Apr 01; 304(7):H966-82.Am J Physiol Heart Circ Physiol2013-01-25T00:00:002013Transplantation of autologously derived mitochondria protects the heart from ischemia-reperfusion injury.16996956Tansey EE, Kwaku KF, Hammer PE, Cowan DB, Federman M, Levitsky S, McCully JDThe Annals of thoracic surgeryReduction and redistribution of gap and adherens junction proteins after ischemia and reperfusion. Ann Thorac Surg. 2006 Oct; 82(4):1472-9.Ann Thorac Surg2006-10-01T00:00:002006Reduction and redistribution of gap and adherens junction proteins after ischemia and reperfusion.8820081Sasaki S, Alessandrini F, Lodi R, McCully J, LoCicero JThe Journal of heart and lung transplantation : the official publication of the International Society for Heart TransplantationImprovement of pulmonary graft after storage for twenty-four hours by in vivo administration of lazaroid U74389G: functional and morphologic analysis. J Heart Lung Transplant. 1996 Jan; 15(1 Pt 1):35-42.J Heart Lung Transplant1996-01-01T00:00:001996Improvement of pulmonary graft after storage for twenty-four hours by in vivo administration of lazaroid U74389G: functional and morphologic analysis.7616120Nanji AA, Griniuviene B, Sadrzadeh SM, Levitsky S, McCully JDJournal of lipid researchEffect of type of dietary fat and ethanol on antioxidant enzyme mRNA induction in rat liver. J Lipid Res. 1995 Apr; 36(4):736-44.J Lipid Res1995-04-01T00:00:001995Effect of type of dietary fat and ethanol on antioxidant enzyme mRNA induction in rat liver.14583312Levitsky S, Laurikka J, Stewart RD, Campos CT, Lahey SJ, McCully JDEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic SurgeryMitochondrial DNA deletions in coronary artery bypass grafting patients. Eur J Cardiothorac Surg. 2003 Nov; 24(5):777-84.Eur J Cardiothorac Surg2003-11-01T00:00:002003Mitochondrial DNA deletions in coronary artery bypass grafting patients.14654062McCully JD, Levitsky SArchives of biochemistry and biophysicsMitochondrial ATP-sensitive potassium channels in surgical cardioprotection. Arch Biochem Biophys. 2003 Dec 15; 420(2):237-45.Arch Biochem Biophys2003-12-15T00:00:002003Mitochondrial ATP-sensitive potassium channels in surgical cardioprotection.23262132Friehs I, Cowan DB, Choi YH, Black KM, Barnett R, Bhasin MK, Daly C, Dillon SJ, Libermann TA, McGowan FX, del Nido PJ, Levitsky S, McCully JDAmerican journal of physiology. Heart and circulatory physiologyPressure-overload hypertrophy of the developing heart reveals activation of divergent gene and protein pathways in the left and right ventricular myocardium. Am J Physiol Heart Circ Physiol. 2013 Mar 01; 304(5):H697-708.Am J Physiol Heart Circ Physiol2012-12-21T00:00:002012Pressure-overload hypertrophy of the developing heart reveals activation of divergent gene and protein pathways in the left and right ventricular myocardium.8069034McCully JD, Tsukube T, Ataka K, Krukenkamp IB, Feinberg H, Levitsky SJournal of cardiac surgeryMyocardial cytosolic calcium accumulation during ischemia/reperfusion: the effects of aging and cardioplegia. J Card Surg. 1994 May; 9(3 Suppl):449-52.J Card Surg1994-05-01T00:00:001994Myocardial cytosolic calcium accumulation during ischemia/reperfusion: the effects of aging and cardioplegia.Authorship 1033110629234096Cowan DB, Yao R, Thedsanamoorthy JK, Zurakowski D, Del Nido PJ, McCully JDScientific reportsTransit and integration of extracellular mitochondria in human heart cells. Sci Rep. 2017 12 12; 7(1):17450.Sci Rep2017-12-12T00:00:002017Transit and integration of extracellular mitochondria in human heart cells.17307466McCully JD, Rousou AJ, Parker RA, Levitsky SThe Annals of thoracic surgeryAge- and gender-related differences in mitochondrial oxygen consumption and calcium with cardioplegia and diazoxide. Ann Thorac Surg. 2007 Mar; 83(3):1102-9.Ann Thorac Surg2007-03-01T00:00:002007Age- and gender-related differences in mitochondrial oxygen consumption and calcium with cardioplegia and diazoxide.8691865Tsukube T, McCully JD, Federman M, Krukenkamp IB, Levitsky SThe Journal of thoracic and cardiovascular surgeryDevelopmental differences in cytosolic calcium accumulation associated with surgically induced global ischemia: optimization of cardioplegic protection and mechanism of action. J Thorac Cardiovasc Surg. 1996 Jul; 112(1):175-84.J Thorac Cardiovasc Surg1996-07-01T00:00:001996Developmental differences in cytosolic calcium accumulation associated with surgically induced global ischemia: optimization of cardioplegic protection and mechanism of action.18978192McCully JD, Cowan DB, Pacak CA, Toumpoulis IK, Dayalan H, Levitsky SAmerican journal of physiology. Heart and circulatory physiologyInjection of isolated mitochondria during early reperfusion for cardioprotection. Am J Physiol Heart Circ Physiol. 2009 Jan; 296(1):H94-H105.Am J Physiol Heart Circ Physiol2008-10-31T00:00:002008Injection of isolated mitochondria during early reperfusion for cardioprotection.11156129Matsuda H, Levitsky S, McCully JDThe Annals of thoracic surgeryInhibition of RNA transcription modulates magnesium-supplemented potassium cardioplegia protection. Ann Thorac Surg. 2000 Dec; 70(6):2107-12.Ann Thorac Surg2000-12-01T00:00:002000Inhibition of RNA transcription modulates magnesium-supplemented potassium cardioplegia protection.Cardiovascular