Harvard Catalyst Profiles

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Sachin Jatin Shah, M.D.

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Biography
Yale University School of MedicineMD2011
Massachusetts General Hospital2014Medicine Residency
Massachusetts General Hospital 2015Chief Resident
Harvard TH Chan School of Public Health MPH2017
Massachusetts General Hospital2017Research fellow (General Medicine & Population Health)
2018
Junior Investigator Recognition Award (best article by junior faculty, Annals of Internal Medicine)
2017
Young Investigator Award (AHA Council on Quality and Outcomes Research)
2011
Ferris Prize for Outstanding Thesis (Yale Medical School)

Overview
I am a physician investigator in the Division of General Internal Medicine and the Center for Aging and Serious Illness at MGH. My research program is dedicated to assisting older adults in making personalized treatment decisions when they face high-stakes medical decisions, like deciding to use blood thinners, use new anti-amyloid treatments for dementia, or undergo a procedure. After completing my training in Internal Medicine and a General Medicine Research Fellowship at Massachusetts General Hospital, I joined the faculty at UCSF. After five years at UCSF, I returned to Massachusetts General Hospital, where I provide clinical care, supervise trainees, and conduct research.

My research program uses epidemiologic methods and core aging concepts to better define the risks and benefits of high-risk therapeutics. High-stakes clinical decisions are those with both substantial benefit and harm. My work focuses on (1) the generalizability of clinical trials to older adults and (2) individualizing estimates of benefit and harm for older adults. I also devote substantial attention to defining and measuring vulnerability in older adults. My work has focused on social vulnerability by defining the interaction between social resources and medical illness. My work is funded by the National Institute on Aging and supported by the Department of Medicine at MGH.

In addition to my research program, I serve as the General Medicine Fellowship Director at MGH and the primary instructor for EPI 946 at the Harvard School of Public Health.

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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.