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Francesca Gori, Ph.D.

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Biography
awards and honors
1993
Sanchez Foundation Award for Young Investigators
2005
Harold Frost Young Investigator Award
2007
John Haddad Young Investigator Award
2021
Burton C. Borgelt/SCADA Faculty Advisor Award

Overview
overview
My longstanding interest is to explore the molecular, cellular and genetic basis of skeletal homeostasis and its regulation in health and disease.WNT signaling controls cell fate decision and tissue homeostasis. WNT signaling in bone has been studied intensively in recent years. However, not all key aspects of how it regulates bone mass are clear and the regulation of signaling specificity between different WNT cascades remain puzzling. Given that WNT signaling can be targeted for drug development, insights into these mechanisms might translate into new therapeutic approaches for rare and common skeletal disorders. Ongoing studies on the role of WNT inhibitors and agonists in skeletal homeostasis are part of the current focus of the lab.

Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R01DE029615 (GORI, FRANCESCA) May 8, 2020 - Apr 30, 2025
    NIH
    Biology of cortical bone of long bones and calvarium: Role of Sfrp4 in periosteal bone formation
    Role: Principal Investigator
  2. R56DE028299 (GORI, FRANCESCA) Aug 1, 2019 - Apr 30, 2020
    NIH
    Biology of cortical bone of long bones and calvarium. Role of Sfrp4 in the local regulation of Wnt signaling
    Role: Principal Investigator
  3. R21DK076093 (GORI, FRANCESCA) Sep 30, 2006 - May 31, 2009
    NIH
    Role of Wdr5, a Novel BMP-2 Induced Gene, in Limb Development
    Role: Principal Investigator
  4. F32DE005754 (GORI, FRANCESCA) Sep 15, 2000
    NIH
    BMP-2 REGULATED GENES DURING ENDOCHONDRAL BONE FORMATION
    Role: Principal Investigator

Bibliographic
selected publications
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© 2024 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.