SP13Shin-YoungParkShin-Young Park, Ph.D.42.33812600000000-71.1049210000000051598Park, Shin-Young617/919-2694Instructor in Pathologycatalyst:eCommonsLogineCommons Loginprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:address2address line 2vivo:address3address line 3vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsvivo:phoneNumberphonePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofvivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson15715669Jiang S, Avraham HK, Park SY, Kim TA, Bu X, Seng S, Avraham SJournal of neurochemistryProcess elongation of oligodendrocytes is promoted by the Kelch-related actin-binding protein Mayven. J Neurochem. 2005 Mar; 92(5):1191-203.J Neurochem2005-03-01T00:00:002005Process elongation of oligodendrocytes is promoted by the Kelch-related actin-binding protein Mayven.Authorship 1079245Authorship 6299801Authorship 6299816Authorship 629982723624405Nombela-Arrieta C, Pivarnik G, Winkel B, Canty KJ, Harley B, Mahoney JE, Park SY, Lu J, Protopopov A, Silberstein LENature cell biologyQuantitative imaging of haematopoietic stem and progenitor cell localization and hypoxic status in the bone marrow microenvironment. Nat Cell Biol. 2013 May; 15(5):533-43.Nat Cell Biol2013-04-28T00:00:002013Quantitative imaging of haematopoietic stem and progenitor cell localization and hypoxic status in the bone marrow microenvironment.17568820Glodek AM, Le Y, Dykxhoorn DM, Park SY, Mostoslavsky G, Mulligan R, Lieberman J, Beggs HE, Honczarenko M, Silberstein LELeukemiaFocal adhesion kinase is required for CXCL12-induced chemotactic and pro-adhesive responses in hematopoietic precursor cells. Leukemia. 2007 Aug; 21(8):1723-32.Leukemia2007-06-14T00:00:002007Focal adhesion kinase is required for CXCL12-induced chemotactic and pro-adhesive responses in hematopoietic precursor cells.18031698Le Y, Zhu BM, Harley B, Park SY, Kobayashi T, Manis JP, Luo HR, Yoshimura A, Hennighausen L, Silberstein LEImmunitySOCS3 protein developmentally regulates the chemokine receptor CXCR4-FAK signaling pathway during B lymphopoiesis. Immunity. 2007 Nov; 27(5):811-23.Immunity2007-11-01T00:00:002007SOCS3 protein developmentally regulates the chemokine receptor CXCR4-FAK signaling pathway during B lymphopoiesis.D000762Concepts & Ideas951570.904207Anesthesia Recovery PeriodD038041Physiology1071320.90904LymphopoiesisD018617Procedures18190.990091Ultrasonography, Doppler, PulsedD051417Chemicals & Drugs841200.945107Focal Adhesion Kinase 1D051418Chemicals & Drugs49860.965543Focal Adhesion Kinase 2EmeritusMedicinePathologyPediatricsPsychiatryRadiologyStem Cell and Regenerative BiologySurgeryHematology/OncologyAdult OncologyImmunologyBrigham and Women's HospitalBoston Children's HospitalDana-Farber Cancer InstituteHarvard Medical SchoolBHE3BEllisB Heidi Ellis, Ph.D.42.33812600000000-71.1049210000000084130Ellis, BAssociate Professor of Psychology in the Department of PsychiatryDTS1DavidScaddenDavid Scadden, M.D.42.37730000000000-71.0525000000000014424Scadden, DavidProfessor of Stem Cell and Regenerative BiologyPJS13PaulSchmidtPaul Jeffrey Schmidt, Ph.D.42.33812600000000-71.1049210000000015312Schmidt, PaulPrincipal Associate in Pathology1122selected publications0.8017930.00253979233research areas0.9931820.019528117coauthor of10.74461.9811660similar toKCA1KennethAndersonKenneth Carl Anderson, M.D.42.33789600000000-71.107249300000008381Anderson, KennethKraft Family Professor of MedicineSY1Seung-SchikYooSeung-Schik Yoo, Ph.D.42.33510370000000-71.1061649000000017361Yoo, Seung-SchikAssociate Professor of RadiologyHL55HongboLuoHongbo Luo, Ph.D.42.33812600000000-71.1049210000000069280Luo, HongboProfessor of PathologyGQD1GeorgeDaleyGeorge Quentin Daley, M.D., Ph.D.42.33812600000000-71.1049210000000062Daley, GeorgeCaroline Shields Walker Professor of MedicineRSG3RaifGehaRaif Salim Geha, M.D.42.33812600000000-71.1049210000000064430Geha, RaifJames L. Gamble Professor of PediatricsJPM6JohnManisJohn P. Manis, M.D.42.33812600000000-71.1049210000000013448Manis, JohnAssociate Professor of PathologyLIZ1LeonardZonLeonard Ira Zon, M.D.42.33743600000000-71.1054470000000060887Zon, LeonardProfessor of Stem Cell and Regenerative BiologyLES4LeslieSilbersteinLeslie E. Silberstein, M.D.42.33812600000000-71.1049210000000049404Silberstein, LeslieProfessor of Pathology, EmeritusMC326M. FeliciaCiuculescuM. Felicia Ciuculescu, M.D.105926Ciuculescu, M. FeliciaResearch Fellow in Pediatricstrue1Associate Professor of RadiologyAssociate Professor of Radiologytrue1Kraft Family Professor of MedicineKraft Family Professor of MedicineAuthorship 1804154BCMPAuthorship 1375201Authorship 1683964true1Professor of Stem Cell and Regenerative BiologyProfessor of Stem Cell and Regenerative Biologytrue1Professor of Pathology, EmeritusProfessor of Pathology, Emeritustrue1Caroline Shields Walker Professor of MedicineCaroline Shields Walker Professor of Medicinetrue1Research Fellow in PediatricsResearch Fellow in Pediatricstrue1Principal Associate in PathologyPrincipal Associate in Pathologytrue1Patricia K. Donahoe Professor of SurgeryPatricia K. Donahoe Professor of Surgerytrue1Associate Professor of PathologyAssociate Professor of Pathologytrue1Professor of PathologyProfessor of Pathologytrue1Instructor in PathologyInstructor in Pathologytrue1Associate Professor of Psychology in the Department of PsychiatryAssociate Professor of Psychology in the Department of Psychiatrytrue1James L. Gamble Professor of PediatricsJames L. Gamble Professor of Pediatricstrue1Professor of Stem Cell and Regenerative BiologyProfessor of Stem Cell and Regenerative Biology21876461Yoo SS, Kim H, Min BK, Franck E, Park SNeuroreportTranscranial focused ultrasound to the thalamus alters anesthesia time in rats. Neuroreport. 2011 Oct 26; 22(15):783-7.Neuroreport2011-10-26T00:00:002011Transcranial focused ultrasound to the thalamus alters anesthesia time in rats.22763009Kim H, Taghados SJ, Fischer K, Maeng LS, Park S, Yoo SSUltrasound in medicine & biologyNoninvasive transcranial stimulation of rat abducens nerve by focused ultrasound. Ultrasound Med Biol. 2012 Sep; 38(9):1568-75.Ultrasound Med Biol2012-07-03T00:00:002012Noninvasive transcranial stimulation of rat abducens nerve by focused ultrasound.Authorship 20221124752297Kumar L, Chou J, Yee CS, Borzutzky A, Vollmann EH, von Andrian UH, Park SY, Hollander G, Manis JP, Poliani PL, Geha RSThe Journal of experimental medicineLeucine-rich repeat containing 8A (LRRC8A) is essential for T lymphocyte development and function. J Exp Med. 2014 May 05; 211(5):929-42.J Exp Med2014-04-21T00:00:002014Leucine-rich repeat containing 8A (LRRC8A) is essential for T lymphocyte development and function.Authorship 7681455Authorship 7683055Authorship 768670522378299Yang PS, Kim H, Lee W, Bohlke M, Park S, Maher TJ, Yoo SSNeuropsychobiologyTranscranial focused ultrasound to the thalamus is associated with reduced extracellular GABA levels in rats. Neuropsychobiology. 2012; 65(3):153-60.Neuropsychobiology2012-02-25T00:00:002012Transcranial focused ultrasound to the thalamus is associated with reduced extracellular GABA levels in rats.Authorship 5490973Authorship 409783Authorship 1306451Authorship 4078682Authorship 5086641Authorship 541216625579427Kwak HJ, Liu P, Bajrami B, Xu Y, Park SY, Nombela-Arrieta C, Mondal S, Sun Y, Zhu H, Chai L, Silberstein LE, Cheng T, Luo HRImmunityMyeloid cell-derived reactive oxygen species externally regulate the proliferation of myeloid progenitors in emergency granulopoiesis. Immunity. 2015 Jan 20; 42(1):159-71.Immunity2015-01-08T00:00:002015Myeloid cell-derived reactive oxygen species externally regulate the proliferation of myeloid progenitors in emergency granulopoiesis.25824687Ciuculescu MF, Park SY, Canty K, Mathieu R, Silberstein LE, Williams DABloodPerivascular deletion of murine Rac reverses the ratio of marrow arterioles and sinusoid vessels and alters hematopoiesis in vivo. Blood. 2015 May 14; 125(20):3105-13.Blood2015-03-30T00:00:002015Perivascular deletion of murine Rac reverses the ratio of marrow arterioles and sinusoid vessels and alters hematopoiesis in vivo.1Associate Professor6Fellow or Post Doc0Full Professor4Instructor5Other FacultyAuthorship 91134010Authorship 9113417Authorship 9113425Authorship 911343227551153Bajrami B, Zhu H, Kwak HJ, Mondal S, Hou Q, Geng G, Karatepe K, Zhang YC, Nombela-Arrieta C, Park SY, Loison F, Sakai J, Xu Y, Silberstein LE, Luo HRThe Journal of experimental medicineG-CSF maintains controlled neutrophil mobilization during acute inflammation by negatively regulating CXCR2 signaling. J Exp Med. 2016 09 19; 213(10):1999-2018.J Exp Med2016-08-22T00:00:002016G-CSF maintains controlled neutrophil mobilization during acute inflammation by negatively regulating CXCR2 signaling.2021-03-31SILBERSTEIN, LESLIE ERIC2009-04-01Molecular Mechanisms of Blood Cell TransfusionP01HL095489Co-Principal InvestigatorTTH13TimothyHlaTimothy T Hla, Ph.D.153463Hla, TimothyPatricia K. Donahoe Professor of SurgeryAuthorship 191701310704819Avraham H, Park SY, Schinkmann K, Avraham SCellular signallingRAFTK/Pyk2-mediated cellular signalling. Cell Signal. 2000 Mar; 12(3):123-33.Cell Signal2000-03-01T00:00:002000RAFTK/Pyk2-mediated cellular signalling.10764815Park SY, Avraham H, Avraham SThe Journal of biological chemistryCharacterization of the tyrosine kinases RAFTK/Pyk2 and FAK in nerve growth factor-induced neuronal differentiation. J Biol Chem. 2000 Jun 30; 275(26):19768-77.J Biol Chem2000-06-30T00:00:002000Characterization of the tyrosine kinases RAFTK/Pyk2 and FAK in nerve growth factor-induced neuronal differentiation.12063569McShan GD, Zagozdzon R, Park SY, Zrihan-Licht S, Fu Y, Avraham S, Avraham HInternational journal of oncologyCsk homologous kinase associates with RAFTK/Pyk2 in breast cancer cells and negatively regulates its activation and breast cancer cell migration. Int J Oncol. 2002 Jul; 21(1):197-205.Int J Oncol2002-07-01T00:00:002002Csk homologous kinase associates with RAFTK/Pyk2 in breast cancer cells and negatively regulates its activation and breast cancer cell migration.16945503Park SY, Li H, Avraham SCellular signallingRAFTK/Pyk2 regulates EGF-induced PC12 cell spreading and movement. Cell Signal. 2007 Feb; 19(2):289-300.Cell Signal2006-08-30T00:00:002006RAFTK/Pyk2 regulates EGF-induced PC12 cell spreading and movement.15166227Park SY, Avraham HK, Avraham SThe Journal of biological chemistryRAFTK/Pyk2 activation is mediated by trans-acting autophosphorylation in a Src-independent manner. J Biol Chem. 2004 Aug 06; 279(32):33315-22.J Biol Chem2004-05-27T00:00:002004RAFTK/Pyk2 activation is mediated by trans-acting autophosphorylation in a Src-independent manner.22155722Lu J, Sun Y, Nombela-Arrieta C, Du KP, Park SY, Chai L, Walkley C, Luo HR, Silberstein LEExperimental hematologyFak depletion in both hematopoietic and nonhematopoietic niche cells leads to hematopoietic stem cell expansion. Exp Hematol. 2012 Apr; 40(4):307-17.e3.Exp Hematol2011-12-08T00:00:002011Fak depletion in both hematopoietic and nonhematopoietic niche cells leads to hematopoietic stem cell expansion.23264658Park SY, Wolfram P, Canty K, Harley B, Nombela-Arrieta C, Pivarnik G, Manis J, Beggs HE, Silberstein LEJournal of immunology (Baltimore, Md. : 1950)Focal adhesion kinase regulates the localization and retention of pro-B cells in bone marrow microenvironments. J Immunol. 2013 Feb 01; 190(3):1094-102.J Immunol2012-12-21T00:00:002012Focal adhesion kinase regulates the localization and retention of pro-B cells in bone marrow microenvironments.18339802Jia Y, Loison F, Hattori H, Li Y, Erneux C, Park SY, Gao C, Chai L, Silberstein LE, Schurmans S, Luo HRProceedings of the National Academy of Sciences of the United States of AmericaInositol trisphosphate 3-kinase B (InsP3KB) as a physiological modulator of myelopoiesis. Proc Natl Acad Sci U S A. 2008 Mar 25; 105(12):4739-44.Proc Natl Acad Sci U S A2008-03-13T00:00:002008Inositol trisphosphate 3-kinase B (InsP3KB) as a physiological modulator of myelopoiesis.11472358Koziak K, Kaczmarek E, Park SY, Fu Y, Avraham S, Avraham HBritish journal of haematologyRAFTK/Pyk2 involvement in platelet activation is mediated by phosphoinositide 3-kinase. Br J Haematol. 2001 Jul; 114(1):134-40.Br J Haematol2001-07-01T00:00:002001RAFTK/Pyk2 involvement in platelet activation is mediated by phosphoinositide 3-kinase.320 Longwood AveChildren's HospitalTransfusion Med/Lab Med, Enders 828320 Longwood AveBoston02115MA23302686Mollova M, Bersell K, Walsh S, Savla J, Das LT, Park SY, Silberstein LE, Dos Remedios CG, Graham D, Colan S, Kühn BProceedings of the National Academy of Sciences of the United States of AmericaCardiomyocyte proliferation contributes to heart growth in young humans. Proc Natl Acad Sci U S A. 2013 Jan 22; 110(4):1446-51.Proc Natl Acad Sci U S A2013-01-09T00:00:002013Cardiomyocyte proliferation contributes to heart growth in young humans.16199135Park SY, Schinkmann KA, Avraham SCellular signallingRAFTK/Pyk2 mediates LPA-induced PC12 cell migration. Cell Signal. 2006 Jul; 18(7):1063-71.Cell Signal2005-09-30T00:00:002005RAFTK/Pyk2 mediates LPA-induced PC12 cell migration.