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Pardis Sabeti, M.D., Ph.D.

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Biography
M.I.T.B.S.1997
University of OxfordM.Sc.1998
University of OxfordD.Phil.2003
Harvard Medical SchoolM.D.2006

Overview
Dr. Sabeti's lab focuses on developing new analytical and genomic methods to study evolutionary adaptation and genetic diversity in humans and pathogens, with three current research foci: (1) Identifying and characterizing the underlying adaptive changes that have shaped the human species over time; and (2) Investigating genetic diversity in pathogens such as Lassa virus, Ebola virus, Zika virus, and Babesia microti, towards improved diagnostics, surveillance, and interventions, and (3) Developing novels tools to detect and diagnose microbes causing human morbidity and mortality.

Dr. Sabeti's computational genomic lab has contributed to widely varying fields — including human evolutionary biology, gene therapy, microbial sequencing, information theory, and disease surveillance. They aim to create comprehensive approaches for detecting, containing, and treating deadly infectious diseases, including Lassa virus, Ebola virus, Zika virus, and SARS-CoV-2. She has invested in capacity building and education throughout, co-founding the African Center for Excellence of Genomic of Infectious Disease, enabling the first diagnosis of Ebola in Sierra Leone and Nigeria, training thousands of scientists through extended educational programs, and establishing genome centers in West Africa.

Mentoring
Family-based Genome-Wide Association Study of Cholera Susceptibility in the Ganges Delta
Summer, 06/07/12 - 08/07/12
Genetic basis of resistance to Lassa Fever in West Africa
Summer, 06/16/14 - 08/15/14

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. U01AI151812 (ANDERSEN, KRISTIAN GRAUGAARD ;GARRY, ROBERT F;SABETI, PARDIS CHRISTINE) May 21, 2020 - Apr 30, 2025
    NIH
    West African Emerging Infectious Disease Research Center (WA-EIDRC)
    Role: Co-Principal Investigator
  2. UM1HG009435 (SABETI, PARDIS CHRISTINE) Sep 12, 2017 - Jun 30, 2022
    NIH
    Comprehensive functional characterization and dissection of noncoding regulatory elements and human genetic variation
    Role: Principal Investigator
  3. R01AI114855 (SABETI, PARDIS CHRISTINE) Jan 5, 2015 - Dec 31, 2019
    NIH
    Elucidating Genetic Determinants of Resistance to Lassa Hemorrhagic Fever
    Role: Principal Investigator
  4. DP2OD006514 (SABETI, PARDIS CHRISTINE) Jan 1, 2010 - Aug 31, 2014
    NIH
    Host and Pathogen Evolution in Lassa Fever
    Role: Principal Investigator

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Bibliographic
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.