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Daniel Edward Neafsey, Ph.D.

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Biography
Loyola University ChicagoBA6/1998Biology
Harvard UniversityPh.D.6/2004Biology

Overview
Daniel Neafsey's laboratory studies the evolutionary genomics of malaria parasites and mosquito vectors. Prior to becoming a faculty member at Harvard, he led a research group at the Broad Institute, where he retains a role as Associate Director of the Broad Institute's Genomic Center for Infectious Disease. He is excited by the potential for new technology and data to turn the tide against diseases like malaria.

Neafsey's current projects involve the application of comparative genomic and population genetic analyses to Plasmodium malaria parasites and Anopheles mosquitoes to study population structure, natural selection, and genomic factors underlying parasite and vector phenotypes that impact public health. Neafsey's interests also include the use of pathogen polymorphism data to inform vaccine design and understand vaccine efficacy, analysis of drug resistance mechanisms and evolution, the use of clinical genotyping data to interpret disease transmission dynamics, and the development of new genomic protocols and informatics tools to address key questions in infectious disease and global health.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AI141544 (NEAFSEY, DANIEL E) Sep 25, 2018 - Aug 31, 2023
    NIH
    Exploring the roles of acquired immunity and functional constraint in sculpting malaria antigenic diversity in a longitudinal cohort
    Role: Principal Investigator
  2. U19AI110818 (BIRREN, BRUCE W. ;NEAFSEY, DANIEL E) Apr 10, 2014 - Mar 31, 2024
    NIH
    Advancing Genomic Technologies to Combat Infectious Disease: Mapping Dynamics within Single Cells, Individual Hosts, and Global Populations
    Role: Co-Principal Investigator

Bibliographic
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.