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Hans-Olov Adami, M.B., M.D., Ph.D.

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Biography
Uppsala University, SwedenM.D.Medicine
Uppsala University, SwedenPh.D.Surgery

Overview
With a long background as a practicing surgeon with a focus on oncology, I have always conducted clinical and epidemiologic research in parallel. My clinical research includes randomized trials, prognostic studies, and studies of clinical issues using an observational study design. Over the years, however, my focus has been on cancer epidemiology, and I have worked on a large number of cancer sites and types. Currently, I am working predominantly on prostate cancer, (with research ranging from genetic association studies to randomized trials of radical surgical treatment, and prediction of outcome using molecular and genetic markers), malignant lymphomas, cervical cancer (with a focus on viral load as a possible determinant of progression from precursors to invasive cancer), and breast cancer. I am also involved in planning a large prospective cohort study in Sweden, and integrating this with other similar initiatives
around the globe.

Other Affiliations

Professor Emeritus, Karolinska Institutet, Stockholm, Sweden
Associate Director of Populations Sciences, Dana Farber/Harvard Cancer Center

Research

My research is devoted chiefly, but not entirely to cancer epidemiology. Within that area, I have been interested in a large number of cancer sites and types and carried out both prospective and case-control studies often on a large-scale within Sweden. Hence, we have conducted nation-wide case-control studies in Sweden on cancers of the breast, cervix, endometrium, ovary, anus, esophagus, non-Hodgkin’s lymphomas, Hodgkin’s lymphomas, kidney cancer and prostate cancer. Much of my research over the last decade has been carried out in close collaboration with professor Trichopoulos at the Harvard School of Public Health and also with other researchers, post docs and graduate students at the SPH. Presently, this work is expanding also into realm of prostate cancer in collaboration with the Dana Farber Cancer Institute. Beside etiologic research into the causes of cancer, I have also a long-standing interest in clinical research including randomized trials, cancer screening and analysis of prognostic factors.

A large part of the research carried out at Harvard and at the Karolinska Institutet in Stockholm takes advantage of unique prerequisites for epidemiologic research in Sweden, including nation-wide cancer registration, a public health care system that allows retrieval of information, hospital records, tissue specimens etc., and an expanding number of national health data bases that can be cross-linked using the individually unique national registration number assigned to all residents in Sweden. This registration number also enables complete follow-up long-term of virtually all individuals included in epidemiologic and clinical studies.

In recent years, collaboration and exchange of Junior Faculty, post docs and graduate students has become an important ingredient in the research carried out collaboratively between Karolinska Institutet and the Harvard School of Public Health. Given the enormous prerequisites for epidemiologic research in Sweden, this is an untapped resource and we have a keen interest in both recruiting post docs from the School of Public Health and in offering graduate students at Harvard opportunities to use Swedish data sources and on-going studies for their thesis work. More information about these opportunities can be obtained for example from Dr. Lorelei Mucci and from Dr. Ellen Chang.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01CA115873 (ADAMI, HANS-OLOV) Sep 22, 2008 - Jul 31, 2016
    NIH
    Gene-environment EBV Interactions in the Etiology of Nasopharyngeal Carcinoma (NP
    Role: Principal Investigator
  2. R01CA111720 (ADAMI, HANS-OLOV) May 1, 2005 - Apr 30, 2009
    NIH
    Molecular epidemiology of cervical adenocarcinoma
    Role: Principal Investigator
  3. R03CA101496 (ADAMI, HANS-OLOV) Jul 1, 2003 - Jun 30, 2005
    NIH
    Genetic variation in DNArepair and the risk for lymphoma
    Role: Principal Investigator
  4. R01CA093378 (ADAMI, HANS-OLOV) Sep 30, 2002 - Aug 31, 2007
    NIH
    Prospective study on viral load of cervical cancer
    Role: Principal Investigator
  5. P20CA093986 (HILAKIVI-CLARKE, LEENA A) Sep 19, 2001 - Apr 30, 2003
    NIH/NCI
    Timing of Dietary Exposures and Breast Cancer Risk
    Role: Co-Principal Investigator

Bibliographic
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.