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Yuan Ma, Ph.D.

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Overview
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As an epidemiologist trained in preventive medicine, cardiovascular epidemiology, and aging epidemiology, Dr. Ma's research interests lie in the epidemiology and prevention of aging-related diseases, with a focus on cardiovascular disease and vascular contributions to brain aging and dementia. Dr. Ma's research work has investigated modifiable vascular risk factors and the development of effective intervention strategies for the prevention of hypertension and cardiovascular disease in prospective cohort studies, randomized trials, and health policy modeling studies. Dr. Ma's current research work aims to improve our understanding of how vascular factors contribute to brain aging and dementia using multidisciplinary approaches that integrate advanced epidemiological methods with cutting-edge neuroimaging techniques, neuropathology data, and multi-omics methods in epidemiological studies. Dr. Ma is a recipient of the American Heart Association Postdoctoral Fellowship Award, the National Academy of Medicine Healthy Longevity Catalyst Award, and the NIH K99 Pathway to Independence Award.
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Research
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  1. R03AG087481 (MA, YUAN) Sep 30, 2024 - Aug 31, 2026
    NIH
    Precision blood pressure control, cognition and adverse events in older adults: detecting heterogeneity in treatment effects in randomized trialsusing machine-learning approaches
    Role: Principal Investigator
  2. R01AG088690 (BOLTON, KELLY LEIGH) Sep 1, 2024 - Jun 30, 2029
    NIH
    The impact of inherited and modifiable risk factors on clonal hematopoiesis and age-related disease
    Role: Harvard site PI
  3. 2000012740 (MA, YUAN) Oct 1, 2021 - Sep 30, 2022
    National Academy of Medicine
    Healthy Longevity Global Competition Catalyst Award
    Role Description: Dynamic Signature of Cuffless Blood Pressure and Risk of Subclinical Brain Disease and Dementia
    Role: Principal Investigator
  4. R00AG071742 (MA, YUAN) Sep 1, 2021 - Feb 28, 2026
    NIH
    Epidemiologic, imaging and pathological studies of the role of blood pressure variability in dementia etiology
    Role: Principal Investigator
  5. K99AG071742 (MA, YUAN) Sep 1, 2021 - Aug 31, 2023
    NIH
    Epidemiologic, imaging and pathological studies of the role of blood pressure variability in dementia etiology
    Role: Principal Investigator

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© 2025 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.