BDL2BruceLevyBruce David Levy, M.D.42.33510370000000-71.1061649000000080544Levy, BruceDavid617/732-7420Parker B. Francis Professor of Medicinecatalyst:eCommonsLogineCommons Loginprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:address2address line 2vivo:address3address line 3vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:middleNamemiddle name or initialvivo:personInPositionpositionsvivo:phoneNumberphonePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofvivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 10468401029420095Olenich S, Waterworth G, Badger GJ, Levy B, Israel E, Langevin HMThe Journal of asthma : official journal of the Association for the Care of AsthmaFlexibility and strength training in asthma: A pilot study. J Asthma. 2018 12; 55(12):1376-1383.J Asthma2018-02-08T00:00:002018Flexibility and strength training in asthma: A pilot study.29437245Abdulnour RE, Howrylak JA, Tavares AH, Douda DN, Henkels KM, Miller TE, Fredenburgh LE, Baron RM, Gomez-Cambronero J, Levy BDJournal of leukocyte biologyPhospholipase D isoforms differentially regulate leukocyte responses to acute lung injury. J Leukoc Biol. 2018 05; 103(5):919-932.J Leukoc Biol2018-02-13T00:00:002018Phospholipase D isoforms differentially regulate leukocyte responses to acute lung injury.12172542Levy BD, De Sanctis GT, Devchand PR, Kim E, Ackerman K, Schmidt BA, Szczeklik W, Drazen JM, Serhan CNNature medicineMulti-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A(4). Nat Med. 2002 Sep; 8(9):1018-23.Nat Med2002-08-12T00:00:002002Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A(4).Authorship 105057711Authorship 105194812Authorship 1052991629523657Sham HP, Walker KH, Abdulnour RE, Krishnamoorthy N, Douda DN, Norris PC, Barkas I, Benito-Figueroa S, Colby JK, Serhan CN, Levy BDJournal of immunology (Baltimore, Md. : 1950)15-epi-Lipoxin A4, Resolvin D2, and Resolvin D3 Induce NF-?B Regulators in Bacterial Pneumonia. J Immunol. 2018 04 15; 200(8):2757-2766.J Immunol2018-03-09T00:00:00201815-epi-Lipoxin A4, Resolvin D2, and Resolvin D3 Induce NF-?B Regulators in Bacterial Pneumonia.29524537Peters MC, Kerr S, Dunican EM, Woodruff PG, Fajt ML, Levy BD, Israel E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, Hastie AT, Bleecker ER, Wenzel SE, Fahy JVThe Journal of allergy and clinical immunologyRefractory airway type 2 inflammation in a large subgroup of asthmatic patients treated with inhaled corticosteroids. J Allergy Clin Immunol. 2019 01; 143(1):104-113.e14.J Allergy Clin Immunol2018-03-07T00:00:002018Refractory airway type 2 inflammation in a large subgroup of asthmatic patients treated with inhaled corticosteroids.29546996Dela Cruz CS, Wunderink RG, Christiani DC, Cormier SA, Crothers K, Doerschuk CM, Evans SE, Goldstein DR, Khatri P, Kobzik L, Kolls JK, Levy BD, Metersky ML, Niederman MS, Nusrat R, Orihuela CJ, Peyrani P, Prince AS, Ramírez JA, Ridge KM, Sethi S, Suratt BT, Sznajder JI, Tsalik EL, Walkey AJ, Yende S, Aggarwal NR, Caler EV, Mizgerd JPAmerican journal of respiratory and critical care medicineFuture Research Directions in Pneumonia. NHLBI Working Group Report. Am J Respir Crit Care Med. 2018 07 15; 198(2):256-263.Am J Respir Crit Care Med2018-07-15T00:00:002018Future Research Directions in Pneumonia. NHLBI Working Group Report.9353124Levy BD, Petasis NA, Serhan CNNaturePolyisoprenyl phosphates in intracellular signalling. Nature. 1997 Oct 30; 389(6654):985-90.Nature1997-10-30T00:00:001997Polyisoprenyl phosphates in intracellular signalling.20529300Bhavsar PK, Levy BD, Hew MJ, Pfeffer MA, Kazani S, Israel E, Chung KFRespiratory researchCorticosteroid suppression of lipoxin A4 and leukotriene B4 from alveolar macrophages in severe asthma. Respir Res. 2010 Jun 07; 11:71.Respir Res2010-06-07T00:00:002010Corticosteroid suppression of lipoxin A4 and leukotriene B4 from alveolar macrophages in severe asthma.29672122Ash SY, Rahaghi FN, Come CE, Ross JC, Colon AG, Cardet-Guisasola JC, Dunican EM, Bleecker ER, Castro M, Fahy JV, Fain SB, Gaston BM, Hoffman EA, Jarjour NN, Mauger DT, Wenzel SE, Levy BD, San Jose Estepar R, Israel E, Washko GRAmerican journal of respiratory and critical care medicinePruning of the Pulmonary Vasculature in Asthma. The Severe Asthma Research Program (SARP) Cohort. Am J Respir Crit Care Med. 2018 07 01; 198(1):39-50.Am J Respir Crit Care Med2018-07-01T00:00:002018Pruning of the Pulmonary Vasculature in Asthma. The Severe Asthma Research Program (SARP) Cohort.Authorship 105943817Authorship 10571951427980032Flitter BA, Hvorecny KL, Ono E, Eddens T, Yang J, Kwak DH, Bahl CD, Hampton TH, Morisseau C, Hammock BD, Liu X, Lee JS, Kolls JK, Levy BD, Madden DR, Bomberger JMProceedings of the National Academy of Sciences of the United States of AmericaPseudomonas aeruginosa sabotages the generation of host proresolving lipid mediators. Proc Natl Acad Sci U S A. 2017 01 03; 114(1):136-141.Proc Natl Acad Sci U S A2016-12-15T00:00:002016Pseudomonas aeruginosa sabotages the generation of host proresolving lipid mediators.29631584DeBoer MD, Phillips BR, Mauger DT, Zein J, Erzurum SC, Fitzpatrick AM, Gaston BM, Myers R, Ross KR, Chmiel J, Lee MJ, Fahy JV, Peters M, Ly NP, Wenzel SE, Fajt ML, Holguin F, Moore WC, Peters SP, Meyers D, Bleecker ER, Castro M, Coverstone AM, Bacharier LB, Jarjour NN, Sorkness RL, Ramratnam S, Irani AM, Israel E, Levy B, Phipatanakul W, Gaffin JM, Gerald Teague WBMC pulmonary medicineEffects of endogenous sex hormones on lung function and symptom control in adolescents with asthma. BMC Pulm Med. 2018 Apr 10; 18(1):58.BMC Pulm Med2018-04-10T00:00:002018Effects of endogenous sex hormones on lung function and symptom control in adolescents with asthma.18568027Haworth O, Cernadas M, Yang R, Serhan CN, Levy BDNature immunologyResolvin E1 regulates interleukin 23, interferon-gamma and lipoxin A4 to promote the resolution of allergic airway inflammation. Nat Immunol. 2008 Aug; 9(8):873-9.Nat Immunol2008-06-22T00:00:002008Resolvin E1 regulates interleukin 23, interferon-gamma and lipoxin A4 to promote the resolution of allergic airway inflammation.19594757Kohli P, Levy BDBritish journal of pharmacologyResolvins and protectins: mediating solutions to inflammation. Br J Pharmacol. 2009 Oct; 158(4):960-71.Br J Pharmacol2009-07-07T00:00:002009Resolvins and protectins: mediating solutions to inflammation.20887750Uddin M, Levy BDProgress in lipid researchResolvins: natural agonists for resolution of pulmonary inflammation. Prog Lipid Res. 2011 Jan; 50(1):75-88.Prog Lipid Res2010-09-29T00:00:002010Resolvins: natural agonists for resolution of pulmonary inflammation.21366479Vaidya A, Kaiser UB, Levy BD, Loscalzo JThe New England journal of medicineClinical problem-solving. Lying low. N Engl J Med. 2011 Mar 03; 364(9):871-5.N Engl J Med2011-03-03T00:00:002011Clinical problem-solving. Lying low.22296081Berzin TM, Greenberger NJ, Levy BD, Loscalzo JThe New England journal of medicineClinical problem-solving. Worth a second look. N Engl J Med. 2012 Feb 02; 366(5):463-8.N Engl J Med2012-02-02T00:00:002012Clinical problem-solving. Worth a second look.Authorship 10630974Authorship 10630026Authorship 10630054Authorship 10631711128779028Wang H, Anthony D, Yatmaz S, Wijburg O, Satzke C, Levy B, Vlahos R, Bozinovski SClinical science (London, England : 1979)Aspirin-triggered resolvin D1 reduces pneumococcal lung infection and inflammation in a viral and bacterial coinfection pneumonia model. Clin Sci (Lond). 2017 Sep 15; 131(18):2347-2362.Clin Sci (Lond)2017-08-24T00:00:002017Aspirin-triggered resolvin D1 reduces pneumococcal lung infection and inflammation in a viral and bacterial coinfection pneumonia model.29717929Krishnamoorthy N, Abdulnour RE, Walker KH, Engstrom BD, Levy BDPhysiological reviewsSpecialized Proresolving Mediators in Innate and Adaptive Immune Responses in Airway Diseases. Physiol Rev. 2018 07 01; 98(3):1335-1370.Physiol Rev2018-07-01T00:00:002018Specialized Proresolving Mediators in Innate and Adaptive Immune Responses in Airway Diseases.Authorship 1065981229757195Serhan CN, Levy BDThe Journal of clinical investigationResolvins in inflammation: emergence of the pro-resolving superfamily of mediators. J Clin Invest. 2018 07 02; 128(7):2657-2669.J Clin Invest2018-05-14T00:00:002018Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators.Authorship 10670743Authorship 106755811Authorship 1068807329352860Barnig C, Frossard N, Levy BDPharmacology & therapeuticsTowards targeting resolution pathways of airway inflammation in asthma. Pharmacol Ther. 2018 06; 186:98-113.Pharmacol Ther2018-01-20T00:00:002018Towards targeting resolution pathways of airway inflammation in asthma.28467866Montgomery MW, Yawetz S, Levy BD, Loscalzo JThe New England journal of medicineBack to the History. N Engl J Med. 2017 05 04; 376(18):1783-1788.N Engl J Med2017-05-04T00:00:002017Back to the History.29782179Abdulnour RE, Gunderson T, Barkas I, Timmons JY, Barnig C, Gong M, Kor DJ, Gajic O, Talmor D, Carter RE, Levy BDAmerican journal of respiratory and critical care medicineEarly Intravascular Events Are Associated with Development of Acute Respiratory Distress Syndrome. A Substudy of the LIPS-A Clinical Trial. Am J Respir Crit Care Med. 2018 06 15; 197(12):1575-1585.Am J Respir Crit Care Med2018-06-15T00:00:002018Early Intravascular Events Are Associated with Development of Acute Respiratory Distress Syndrome. A Substudy of the LIPS-A Clinical Trial.20592300Liu AY, Lowe RC, Levy BD, Katz JT, Loscalzo JThe New England journal of medicineClinical problem-solving. A rash hypothesis. N Engl J Med. 2010 Jul 01; 363(1):72-8.N Engl J Med2010-07-01T00:00:002010Clinical problem-solving. A rash hypothesis.21515793Haworth O, Cernadas M, Levy BDJournal of immunology (Baltimore, Md. : 1950)NK cells are effectors for resolvin E1 in the timely resolution of allergic airway inflammation. J Immunol. 2011 Jun 01; 186(11):6129-35.J Immunol2011-04-22T00:00:002011NK cells are effectors for resolvin E1 in the timely resolution of allergic airway inflammation.22215599Bozinovski S, Uddin M, Vlahos R, Thompson M, McQualter JL, Merritt AS, Wark PA, Hutchinson A, Irving LB, Levy BD, Anderson GPProceedings of the National Academy of Sciences of the United States of AmericaSerum amyloid A opposes lipoxin A4 to mediate glucocorticoid refractory lung inflammation in chronic obstructive pulmonary disease. Proc Natl Acad Sci U S A. 2012 Jan 17; 109(3):935-40.Proc Natl Acad Sci U S A2012-01-03T00:00:002012Serum amyloid A opposes lipoxin A4 to mediate glucocorticoid refractory lung inflammation in chronic obstructive pulmonary disease.12088274Levy BD, Serhan CNCellular and molecular life sciences : CMLSPolyisoprenyl phosphates: natural antiinflammatory lipid signals. Cell Mol Life Sci. 2002 May; 59(5):729-41.Cell Mol Life Sci2002-05-01T00:00:002002Polyisoprenyl phosphates: natural antiinflammatory lipid signals.12751730Levy BD, De Sanctis GT, Devchand PR, Kim E, Ackerman K, Schmidt B, Szczeklik W, Drazen JM, Serhan CNAdvances in experimental medicine and biologyLipoxins and aspirin-triggered lipoxins in airway responses. Adv Exp Med Biol. 2003; 525:19-23.Adv Exp Med Biol2003-01-01T00:00:002003Lipoxins and aspirin-triggered lipoxins in airway responses.20227865Levy BDProstaglandins, leukotrienes, and essential fatty acidsResolvins and protectins: natural pharmacophores for resolution biology. Prostaglandins Leukot Essent Fatty Acids. 2010 Apr-Jun; 82(4-6):327-32.Prostaglandins Leukot Essent Fatty Acids2010-03-15T00:00:002010Resolvins and protectins: natural pharmacophores for resolution biology.17991792Sorkness RL, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Chung KF, Curran-Everett D, Erzurum SC, Gaston BM, Israel E, Jarjour NN, Moore WC, Peters SP, Teague WG, Wenzel SEJournal of applied physiology (Bethesda, Md. : 1985)Lung function in adults with stable but severe asthma: air trapping and incomplete reversal of obstruction with bronchodilation. J Appl Physiol (1985). 2008 Feb; 104(2):394-403.J Appl Physiol (1985)2007-11-08T00:00:002007Lung function in adults with stable but severe asthma: air trapping and incomplete reversal of obstruction with bronchodilation.18635886Lara A, Khatri SB, Wang Z, Comhair SA, Xu W, Dweik RA, Bodine M, Levison BS, Hammel J, Bleecker E, Busse W, Calhoun WJ, Castro M, Chung KF, Curran-Everett D, Gaston B, Israel E, Jarjour N, Moore W, Peters SP, Teague WG, Wenzel S, Hazen SL, Erzurum SCAmerican journal of respiratory and critical care medicineAlterations of the arginine metabolome in asthma. Am J Respir Crit Care Med. 2008 Oct 01; 178(7):673-81.Am J Respir Crit Care Med2008-07-17T00:00:002008Alterations of the arginine metabolome in asthma.20638236Katz JN, Wright J, Levy BA, Baron JA, Losina EJournal of clinical epidemiologyDepartures from community equipoise may lead to incorrect inference in randomized trials. J Clin Epidemiol. 2011 Mar; 64(3):280-5.J Clin Epidemiol2010-07-17T00:00:002010Departures from community equipoise may lead to incorrect inference in randomized trials.30076281Krishnamoorthy N, Douda DN, Brüggemann TR, Ricklefs I, Duvall MG, Abdulnour RE, Martinod K, Tavares L, Wang X, Cernadas M, Israel E, Mauger DT, Bleecker ER, Castro M, Erzurum SC, Gaston BM, Jarjour NN, Wenzel S, Dunican E, Fahy JV, Irimia D, Wagner DD, Levy BDScience immunologyNeutrophil cytoplasts induce TH17 differentiation and skew inflammation toward neutrophilia in severe asthma. Sci Immunol. 2018 08 03; 3(26).Sci Immunol2018-08-03T00:00:002018Neutrophil cytoplasts induce TH17 differentiation and skew inflammation toward neutrophilia in severe asthma.Authorship 1085642236490622Mecham RP, Morris SL, Levy BD, Wrenn DSThe Journal of biological chemistryGlucocorticoids stimulate elastin production in differentiated bovine ligament fibroblasts but do not induce elastin synthesis in undifferentiated cells. J Biol Chem. 1984 Oct 25; 259(20):12414-8.J Biol Chem1984-10-25T00:00:001984Glucocorticoids stimulate elastin production in differentiated bovine ligament fibroblasts but do not induce elastin synthesis in undifferentiated cells.21321188Hilberath JN, Carlo T, Pfeffer MA, Croze RH, Hastrup F, Levy BDFASEB journal : official publication of the Federation of American Societies for Experimental BiologyResolution of Toll-like receptor 4-mediated acute lung injury is linked to eicosanoids and suppressor of cytokine signaling 3. FASEB J. 2011 Jun; 25(6):1827-35.FASEB J2011-02-14T00:00:002011Resolution of Toll-like receptor 4-mediated acute lung injury is linked to eicosanoids and suppressor of cytokine signaling 3.22095547Jarjour NN, Erzurum SC, Bleecker ER, Calhoun WJ, Castro M, Comhair SA, Chung KF, Curran-Everett D, Dweik RA, Fain SB, Fitzpatrick AM, Gaston BM, Israel E, Hastie A, Hoffman EA, Holguin F, Levy BD, Meyers DA, Moore WC, Peters SP, Sorkness RL, Teague WG, Wenzel SE, Busse WWAmerican journal of respiratory and critical care medicineSevere asthma: lessons learned from the National Heart, Lung, and Blood Institute Severe Asthma Research Program. Am J Respir Crit Care Med. 2012 Feb 15; 185(4):356-62.Am J Respir Crit Care Med2011-11-17T00:00:002011Severe asthma: lessons learned from the National Heart, Lung, and Blood Institute Severe Asthma Research Program.Authorship 1091366730191175Loynes CA, Lee JA, Robertson AL, Steel MJ, Ellett F, Feng Y, Levy BD, Whyte MKB, Renshaw SAScience advancesPGE2 production at sites of tissue injury promotes an anti-inflammatory neutrophil phenotype and determines the outcome of inflammation resolution in vivo. Sci Adv. 2018 09; 4(9):eaar8320.Sci Adv2018-09-05T00:00:002018PGE2 production at sites of tissue injury promotes an anti-inflammatory neutrophil phenotype and determines the outcome of inflammation resolution in vivo.19797286Wolpin BM, Weller PF, Katz JT, Levy BD, Loscalzo JThe New England journal of medicineClinical problem-solving. The writing on the wall. N Engl J Med. 2009 Oct 01; 361(14):1387-92.N Engl J Med2009-10-01T00:00:002009Clinical problem-solving. The writing on the wall.20375407McMahon GT, Katz JT, Thorndike ME, Levy BD, Loscalzo JThe New England journal of medicineEvaluation of a redesign initiative in an internal-medicine residency. N Engl J Med. 2010 Apr 08; 362(14):1304-11.N Engl J Med2010-04-08T00:00:002010Evaluation of a redesign initiative in an internal-medicine residency.23293638Levy BDFrontiers in immunologyResolvin D1 and Resolvin E1 Promote the Resolution of Allergic Airway Inflammation via Shared and Distinct Molecular Counter-Regulatory Pathways. Front Immunol. 2012; 3:390.Front Immunol2012-12-28T00:00:002012Resolvin D1 and Resolvin E1 Promote the Resolution of Allergic Airway Inflammation via Shared and Distinct Molecular Counter-Regulatory Pathways.Authorship 125220717625069Levy BD, Lukacs NW, Berlin AA, Schmidt B, Guilford WJ, Serhan CN, Parkinson JFFASEB journal : official publication of the Federation of American Societies for Experimental BiologyLipoxin A4 stable analogs reduce allergic airway responses via mechanisms distinct from CysLT1 receptor antagonism. FASEB J. 2007 Dec; 21(14):3877-84.FASEB J2007-07-11T00:00:002007Lipoxin A4 stable analogs reduce allergic airway responses via mechanisms distinct from CysLT1 receptor antagonism.Authorship 1098002630315138Karra L, Singh Gangwar R, Shamri R, Puzzovio PG, Cohen-Mor S, Levy BD, Levi-Schaffer FJournal of immunology (Baltimore, Md. : 1950)Leukocyte CD300a Contributes to the Resolution of Murine Allergic Inflammation. J Immunol. 2018 11 15; 201(10):2998-3005.J Immunol2018-10-12T00:00:002018Leukocyte CD300a Contributes to the Resolution of Murine Allergic Inflammation.21167411Boyce JA, Assa'ad A, Burks AW, Jones SM, Sampson HA, Wood RA, Plaut M, Cooper SF, Fenton MJ, Arshad SH, Bahna SL, Beck LA, Byrd-Bredbenner C, Camargo CA, Eichenfield L, Furuta GT, Hanifin JM, Jones C, Kraft M, Levy BD, Lieberman P, Luccioli S, McCall KM, Schneider LC, Simon RA, Simons FE, Teach SJ, Yawn BP, Schwaninger JMJournal of the American Academy of DermatologyGuidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-Sponsored Expert Panel report. J Am Acad Dermatol. 2011 Jan; 64(1):175-92.J Am Acad Dermatol2011-01-01T00:00:002011Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-Sponsored Expert Panel report.21208111Miller AL, Schissel S, Levy BD, Loscalzo JThe New England journal of medicineClinical problem-solving. A crazy cause of dyspnea. N Engl J Med. 2011 Jan 06; 364(1):72-7.N Engl J Med2011-01-06T00:00:002011Clinical problem-solving. A crazy cause of dyspnea.2982853Mecham RP, Levy BD, Morris SL, Madaras JG, Wrenn DSThe Journal of biological chemistryIncreased cyclic GMP levels lead to a stimulation of elastin production in ligament fibroblasts that is reversed by cyclic AMP. J Biol Chem. 1985 Mar 25; 260(6):3255-8.J Biol Chem1985-03-25T00:00:001985Increased cyclic GMP levels lead to a stimulation of elastin production in ligament fibroblasts that is reversed by cyclic AMP.22802419Rogerio AP, Haworth O, Croze R, Oh SF, Uddin M, Carlo T, Pfeffer MA, Priluck R, Serhan CN, Levy BDJournal of immunology (Baltimore, Md. : 1950)Resolvin D1 and aspirin-triggered resolvin D1 promote resolution of allergic airways responses. J Immunol. 2012 Aug 15; 189(4):1983-91.J Immunol2012-07-16T00:00:002012Resolvin D1 and aspirin-triggered resolvin D1 promote resolution of allergic airways responses.Authorship 1109928430380383Downing NS, McMullan CJ, Rennke HG, Levy BD, Loscalzo JThe New England journal of medicineComplements from the Lung. N Engl J Med. 2018 Nov 01; 379(18):1767-1773.N Engl J Med2018-11-01T00:00:002018Complements from the Lung.18583575Planagumà A, Kazani S, Marigowda G, Haworth O, Mariani TJ, Israel E, Bleecker ER, Curran-Everett D, Erzurum SC, Calhoun WJ, Castro M, Chung KF, Gaston B, Jarjour NN, Busse WW, Wenzel SE, Levy BDAmerican journal of respiratory and critical care medicineAirway lipoxin A4 generation and lipoxin A4 receptor expression are decreased in severe asthma. Am J Respir Crit Care Med. 2008 Sep 15; 178(6):574-82.Am J Respir Crit Care Med2008-06-26T00:00:002008Airway lipoxin A4 generation and lipoxin A4 receptor expression are decreased in severe asthma.Authorship 11188235Authorship 1119446330573389Duvall MG, Krishnamoorthy N, Levy BDAllergology international : official journal of the Japanese Society of AllergologyNon-type 2 inflammation in severe asthma is propelled by neutrophil cytoplasts and maintained by defective resolution. Allergol Int. 2019 Apr; 68(2):143-149.Allergol Int2018-12-17T00:00:002018Non-type 2 inflammation in severe asthma is propelled by neutrophil cytoplasts and maintained by defective resolution.Authorship 11263409Authorship 11249601930635198Fitzpatrick AM, Gillespie SE, Mauger DT, Phillips BR, Bleecker ER, Israel E, Meyers DA, Moore WC, Sorkness RL, Wenzel SE, Bacharier LB, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston BM, Jarjour NN, Larkin A, Levy BD, Ly NP, Ortega VE, Peters SP, Phipatanakul W, Ramratnam S, Teague WGThe Journal of allergy and clinical immunologyRacial disparities in asthma-related health care use in the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. J Allergy Clin Immunol. 2019 06; 143(6):2052-2061.J Allergy Clin Immunol2019-01-08T00:00:002019Racial disparities in asthma-related health care use in the National Heart, Lung, and Blood Institute's Severe Asthma Research Program.28982736Hvorecny KL, Dolben E, Moreau-Marquis S, Hampton TH, Shabaneh TB, Flitter BA, Bahl CD, Bomberger JM, Levy BD, Stanton BA, Hogan DA, Madden DRAmerican journal of physiology. Lung cellular and molecular physiologyAn epoxide hydrolase secreted by Pseudomonas aeruginosa decreases mucociliary transport and hinders bacterial clearance from the lung. Am J Physiol Lung Cell Mol Physiol. 2018 01 01; 314(1):L150-L156.Am J Physiol Lung Cell Mol Physiol2017-10-05T00:00:002017An epoxide hydrolase secreted by Pseudomonas aeruginosa decreases mucociliary transport and hinders bacterial clearance from the lung.Authorship 11277941330682261Wu W, Bang S, Bleecker ER, Castro M, Denlinger L, Erzurum SC, Fahy JV, Fitzpatrick AM, Gaston BM, Hastie AT, Israel E, Jarjour NN, Levy BD, Mauger DT, Meyers DA, Moore WC, Peters M, Phillips BR, Phipatanakul W, Sorkness RL, Wenzel SEAmerican journal of respiratory and critical care medicineMultiview Cluster Analysis Identifies Variable Corticosteroid Response Phenotypes in Severe Asthma. Am J Respir Crit Care Med. 2019 06 01; 199(11):1358-1367.Am J Respir Crit Care Med2019-06-01T00:00:002019Multiview Cluster Analysis Identifies Variable Corticosteroid Response Phenotypes in Severe Asthma.7825838Serhan CN, Fiore S, Levy BDAnnals of the New York Academy of SciencesCell-cell interactions in lipoxin generation and characterization of lipoxin A4 receptors. Ann N Y Acad Sci. 1994 Nov 15; 744:166-80.Ann N Y Acad Sci1994-11-15T00:00:001994Cell-cell interactions in lipoxin generation and characterization of lipoxin A4 receptors.Authorship 115534130815060Bell DS, Baldwin K, Bell EJ, Lehmann CU, Webber EC, Mohan V, Leu MG, Hofmann JM, Kaelber DC, Landman AB, Hron J, Silverman HD, Levy B, Elkin PL, Poon E, Luberti AA, Finnell JT, Safran C, Palma JP, Forman BH, Kileen J, Arvin D, Pfeffer MAMIA ... Annual Symposium proceedings. AMIA SymposiumCharacteristics of the National Applicant Pool for Clinical Informatics Fellowships (2016-2017). AMIA Annu Symp Proc. 2018; 2018:225-231.AMIA Annu Symp Proc2018-12-05T00:00:002018Characteristics of the National Applicant Pool for Clinical Informatics Fellowships (2016-2017).Authorship 113494213D018836Chemicals & Drugs103218900.509323Inflammation MediatorsD044045Chemicals & Drugs644110.786666LipoxinsD007249Disorders3342105340.240895Inflammation30888839Lachowicz-Scroggins ME, Dunican EM, Charbit AR, Raymond W, Looney MR, Peters MC, Gordon ED, Woodruff PG, Lefrançais E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, Hastie AT, Bleecker ER, Fajt ML, Wenzel SE, Israel E, Levy BD, Fahy JVAmerican journal of respiratory and critical care medicineExtracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma. Am J Respir Crit Care Med. 2019 05 01; 199(9):1076-1085.Am J Respir Crit Care Med2019-05-01T00:00:002019Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma.D001249Disorders114159500.259889AsthmaAuthorship 114877330Authorship 115075323D004281Chemicals & Drugs2548730.602761Docosahexaenoic AcidsAnaesthesiaMedicinePediatricsCardiovascular MedicineEmergency MedicinePulmonaryImmunologyDivision of Medical CommunicationsChanning Division of Network MedicineBrigham and Women's HospitalBoston Children's HospitalMassachusetts General HospitalJL132JosephLoscalzoJoseph Loscalzo, M.D.42.33510370000000-71.1061649000000030611Loscalzo, JosephSamuel A. Levine Professor of Medicine; Hersey Distinguished Professor of the Theory and Practice of Physic11246selected publications7.802510.00228254900research areas8.85260.0154657187coauthor of556.71924.842860similar toGH23GaryHunninghakeGary Hunninghake, M.D.42.33510370000000-71.1061649000000041479Hunninghake, GaryAssociate Professor of MedicineSTW1ScottWeissScott Tillman Weiss, M.D.42.33669100000000-71.1020890000000050689Weiss, ScottProfessor of MedicineEI1ElliotIsraelElliot Israel, M.D.42.33510370000000-71.1061649000000011018Israel, ElliotProfessor of MedicineCNS3CharlesSerhanCharles Nicholas Serhan, Ph.D.42.33510370000000-71.1061649000000017417Serhan, CharlesSimon Gelman Professor of AnaesthesiaREA10Raja-ElieAbdulnourRaja-Elie E Abdulnour, M.D.42.36241700000000-71.0689370000000059090Abdulnour, Raja-ElieAssistant Professor of Medicine, Part-timeCAC9CarlosCamargoCarlos Arturo Camargo, Jr., Dr.P.H., M.D.42.36100000000000-71.0691983000000025636Camargo, CarlosProfessor of Emergency MedicineBAC4BarbaraCockrillBarbara Ann Cockrill, M.D.42.33510370000000-71.106164900000006665Cockrill, BarbaraGeorge E. Thibault Academy Associate Professor of MedicineRMB3RebeccaBaronRebecca Marlene Baron, M.D.42.33510370000000-71.1061649000000047642Baron, RebeccaAssociate Professor of MedicineMCL11Mei-YuLeeMei-Yu Chen Lee, M.D.42.33510370000000-71.1061649000000032109Lee, Mei-YuResearch Associate in MedicineWP3WandaPhipatanakulWanda Phipatanakul, M.D.42.33743600000000-71.1054470000000064109Phipatanakul, WandaS. Jean Emans, MD, Professor of PediatricsMGD10MelodyDuvallMelody Gayle Duvall, M.D., Ph.D.42.33743600000000-71.1054470000000011190Duvall, MelodyAssistant Professor of AnaesthesiaHJG4HilaryGoldbergHilary Jennifer Goldberg, M.D.42.33510370000000-71.1061649000000072092Goldberg, HilaryAssistant Professor of MedicineAuthorship 1181977831439681Kelly RS, Chawes BL, Guo F, Zhang L, Blighe K, Litonjua AA, Raby BA, Levy BD, Rago D, Stokholm J, Bønnelykke K, Bisgaard H, Zhou X, Lasky-Su JA, Weiss STThe European respiratory journalThe role of the 17q21 genotype in the prevention of early childhood asthma and recurrent wheeze by vitamin D. Eur Respir J. 2019 10; 54(4).Eur Respir J2019-10-24T00:00:002019The role of the 17q21 genotype in the prevention of early childhood asthma and recurrent wheeze by vitamin D.31521672Ash SY, Sanchez-Ferrero GV, Schiebler ML, Rahaghi FN, Rai A, Come CE, Ross JC, Colon AG, Cardet JC, Bleecker ER, Castro M, Fahy JV, Fain SB, Gaston BM, Hoffman EA, Jarjour NN, Lempel JK, Mauger DT, Tattersall MC, Wenzel SE, Levy BD, Washko GR, Israel E, San Jose Estepar RChestEstimated Ventricular Size, Asthma Severity, and Exacerbations: The Severe Asthma Research Program III Cohort. Chest. 2020 02; 157(2):258-267.Chest2019-09-12T00:00:002019Estimated Ventricular Size, Asthma Severity, and Exacerbations: The Severe Asthma Research Program III Cohort.Authorship 118894621Authorship 119108614Authorship 1191198331513878Li X, Hastie AT, Peters MC, Hawkins GA, Phipatanakul W, Li H, Moore WC, Busse WW, Castro M, Erzurum SC, Gaston B, Israel E, Jarjour NN, Levy BD, Wenzel SE, Meyers DA, Fahy JV, Bleecker ERThe Journal of allergy and clinical immunologyInvestigation of the relationship between IL-6 and type 2 biomarkers in patients with severe asthma. J Allergy Clin Immunol. 2020 01; 145(1):430-433.J Allergy Clin Immunol2019-09-09T00:00:002019Investigation of the relationship between IL-6 and type 2 biomarkers in patients with severe asthma.31524861Tavares AH, Colby JK, Levy BD, Abdulnour REJournal of visualized experiments : JoVEA Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation. J Vis Exp. 2019 08 30; (150).J Vis Exp2019-08-30T00:00:002019A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation.31577880Vallurupalli M, Divakaran S, Parnes A, Levy BD, Loscalzo JThe New England journal of medicineThe Element of Surprise. N Engl J Med. 2019 10 03; 381(14):1365-1371.N Engl J Med2019-10-03T00:00:002019The Element of Surprise.2024-06-30LEVY, BRUCE D2019-09-23Immunometabolic phenotypes in adult severe asthma and disease progressionR01HL146002Principal InvestigatorAuthorship 1600003Authorship 11957344Authorship 119694616Authorship 11976421Authorship 11978701531622688Ross KR, Gupta R, DeBoer MD, Zein J, Phillips BR, Mauger DT, Li C, Myers RE, Phipatanakul W, Fitzpatrick AM, Ly NP, Bacharier LB, Jackson DJ, Celedón JC, Larkin A, Israel E, Levy B, Fahy JV, Castro M, Bleecker ER, Meyers D, Moore WC, Wenzel SE, Jarjour NN, Erzurum SC, Teague WG, Gaston BThe Journal of allergy and clinical immunologySevere asthma during childhood and adolescence: A longitudinal study. J Allergy Clin Immunol. 2020 01; 145(1):140-146.e9.J Allergy Clin Immunol2019-10-14T00:00:002019Severe asthma during childhood and adolescence: A longitudinal study.31604686Wallrapp A, Burkett PR, Riesenfeld SJ, Kim SJ, Christian E, Abdulnour RE, Thakore PI, Schnell A, Lambden C, Herbst RH, Khan P, Tsujikawa K, Xavier RJ, Chiu IM, Levy BD, Regev A, Kuchroo VKImmunityCalcitonin Gene-Related Peptide Negatively Regulates Alarmin-Driven Type 2 Innate Lymphoid Cell Responses. Immunity. 2019 10 15; 51(4):709-723.e6.Immunity2019-10-08T00:00:002019Calcitonin Gene-Related Peptide Negatively Regulates Alarmin-Driven Type 2 Innate Lymphoid Cell Responses.31622689Levy BD, Abdulnour RE, Tavares A, Brüggemann TR, Norris PC, Bai Y, Ai X, Serhan CNThe Journal of allergy and clinical immunologyCysteinyl maresins regulate the prophlogistic lung actions of cysteinyl leukotrienes. J Allergy Clin Immunol. 2020 01; 145(1):335-344.J Allergy Clin Immunol2019-10-14T00:00:002019Cysteinyl maresins regulate the prophlogistic lung actions of cysteinyl leukotrienes.31604088Fitzpatrick AM, Szefler SJ, Mauger DT, Phillips BR, Denlinger LC, Moore WC, Sorkness RL, Wenzel SE, Gergen PJ, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Israel E, Levy BD, Meyers DA, Teague WG, Bacharier LB, Ly NP, Phipatanakul W, Ross KR, Zein J, Jarjour NNThe Journal of allergy and clinical immunologyDevelopment and initial validation of the Asthma Severity Scoring System (ASSESS). J Allergy Clin Immunol. 2020 01; 145(1):127-139.J Allergy Clin Immunol2019-10-08T00:00:002019Development and initial validation of the Asthma Severity Scoring System (ASSESS).Authorship 12031352731712645Jundi B, Ryu H, Lee DH, Abdulnour RE, Engstrom BD, Duvall MG, Higuera A, Pinilla-Vera M, Benson ME, Lee J, Krishnamoorthy N, Baron RM, Han J, Voldman J, Levy BDNature biomedical engineeringLeukocyte function assessed via serial microlitre sampling of peripheral blood from sepsis patients correlates with disease severity. Nat Biomed Eng. 2019 12; 3(12):961-973.Nat Biomed Eng2019-11-11T00:00:002019Leukocyte function assessed via serial microlitre sampling of peripheral blood from sepsis patients correlates with disease severity.Authorship 120567815true1Instructor in MedicineInstructor in Medicinetrue1Assistant Professor of MedicineAssistant Professor of Medicinetrue1Professor of MedicineProfessor of Medicinetrue1Simon Gelman Professor of AnaesthesiaSimon Gelman Professor of Anaesthesiatrue1Associate Professor of MedicineAssociate Professor of MedicineAuthorship 1218081031800992Thomas C, Vleugels RA, Kwiatkowski DJ, Levy B, Loscalzo JThe New England journal of medicineFacing Uncertainty. N Engl J Med. 2019 Dec 05; 381(23):2253-2259.N Engl J Med2019-12-05T00:00:002019Facing Uncertainty.Authorship 12065404Authorship 162543Authorship 12193302431932420Zein J, Gaston B, Bazeley P, DeBoer MD, Igo RP, Bleecker ER, Meyers D, Comhair S, Marozkina NV, Cotton C, Patel M, Alyamani M, Xu W, Busse WW, Calhoun WJ, Ortega V, Hawkins GA, Castro M, Chung KF, Fahy JV, Fitzpatrick AM, Israel E, Jarjour NN, Levy B, Mauger DT, Moore WC, Noel P, Peters SP, Teague WG, Wenzel SE, Erzurum SC, Sharifi NProceedings of the National Academy of Sciences of the United States of AmericaHSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma. Proc Natl Acad Sci U S A. 2020 01 28; 117(4):2187-2193.Proc Natl Acad Sci U S A2020-01-13T00:00:002020HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma.Authorship 12201811131954778Talbot S, Doyle B, Huang J, Wang JC, Ahmadi M, Roberson DP, Yekkirala A, Foster SL, Browne LE, Bean BP, Levy BD, Woolf CJThe Journal of allergy and clinical immunologyVagal sensory neurons drive mucous cell metaplasia. J Allergy Clin Immunol. 2020 06; 145(6):1693-1696.e4.J Allergy Clin Immunol2020-01-16T00:00:002020Vagal sensory neurons drive mucous cell metaplasia.Authorship 1165631Authorship 12327358Authorship 12327671432150460Semler MW, Bernard GR, Aaron SD, Angus DC, Biros MH, Brower RG, Calfee CS, Colantuoni EA, Ferguson ND, Gong MN, Hopkins RO, Hough CL, Iwashyna TJ, Levy BD, Martin TR, Matthay MA, Mizgerd JP, Moss M, Needham DM, Self WH, Seymour CW, Stapleton RD, Thompson BT, Wunderink RG, Aggarwal NR, Reineck LAAmerican journal of respiratory and critical care medicineIdentifying Clinical Research Priorities in Adult Pulmonary and Critical Care. NHLBI Working Group Report. Am J Respir Crit Care Med. 2020 Aug 15; 202(4):511-523.Am J Respir Crit Care Med2020-08-15T00:00:002020Identifying Clinical Research Priorities in Adult Pulmonary and Critical Care. NHLBI Working Group Report.32032631Hastie AT, Mauger DT, Denlinger LC, Coverstone A, Castro M, Erzurum S, Jarjour N, Levy BD, Meyers DA, Moore WC, Phillips B, Wenzel SE, Fahy JV, Israel E, Bleecker ERThe Journal of allergy and clinical immunologyBaseline sputum eosinophil + neutrophil subgroups' clinical characteristics and longitudinal trajectories for NHLBI Severe Asthma Research Program (SARP 3) cohort. J Allergy Clin Immunol. 2020 07; 146(1):222-226.J Allergy Clin Immunol2020-02-05T00:00:002020Baseline sputum eosinophil + neutrophil subgroups' clinical characteristics and longitudinal trajectories for NHLBI Severe Asthma Research Program (SARP 3) cohort.Authorship 124417020Authorship 1243354832348692Peters MC, Sajuthi S, Deford P, Christenson S, Rios CL, Montgomery MT, Woodruff PG, Mauger DT, Erzurum SC, Johansson MW, Denlinger LC, Jarjour NN, Castro M, Hastie AT, Moore W, Ortega VE, Bleecker ER, Wenzel SE, Israel E, Levy BD, Seibold MA, Fahy JVAmerican journal of respiratory and critical care medicineCOVID-19-related Genes in Sputum Cells in Asthma. Relationship to Demographic Features and Corticosteroids. Am J Respir Crit Care Med. 2020 07 01; 202(1):83-90.Am J Respir Crit Care Med2020-07-01T00:00:002020COVID-19-related Genes in Sputum Cells in Asthma. Relationship to Demographic Features and Corticosteroids.32356668Chotirmall SH, Martinez FJ, Schumacker PT, Cooke CR, Seam N, Brochard L, Tighe RM, Levy BD, Gern D, Wedzicha JAAmerican journal of respiratory and critical care medicineLife at the Editorial "COVID Frontline". The American Thoracic Society Journal Family. Am J Respir Crit Care Med. 2020 06 15; 201(12):1457-1459.Am J Respir Crit Care Med2020-06-15T00:00:002020Life at the Editorial "COVID Frontline". The American Thoracic Society Journal Family.Authorship 1252400832479111Peters MC, Mauger D, Ross KR, Phillips B, Gaston B, Cardet JC, Israel E, Levy BD, Phipatanakul W, Jarjour NN, Castro M, Wenzel SE, Hastie A, Moore W, Bleecker E, Fahy JV, Denlinger LCAmerican journal of respiratory and critical care medicineEvidence for Exacerbation-Prone Asthma and Predictive Biomarkers of Exacerbation Frequency. Am J Respir Crit Care Med. 2020 10 01; 202(7):973-982.Am J Respir Crit Care Med2020-10-01T00:00:002020Evidence for Exacerbation-Prone Asthma and Predictive Biomarkers of Exacerbation Frequency.Authorship 1265800632641387Duvall MG, Fuhlbrigge ME, Reilly RB, Walker KH, Kiliç A, Levy BDJournal of immunology (Baltimore, Md. : 1950)Human NK Cell Cytoskeletal Dynamics and Cytotoxicity Are Regulated by LIM Kinase. J Immunol. 2020 08 01; 205(3):801-810.J Immunol2020-07-08T00:00:002020Human NK Cell Cytoskeletal Dynamics and Cytotoxicity Are Regulated by LIM Kinase.Authorship 1271395172024-06-30ARONICA, MARK A;CASTRO, MARIO ;COMHAIR, SUZY ;DENLINGER, LOREN C;HOFFMAN, ERIC ALFRED;ISRAEL, ELLIOT ;KHATRI, PURVESHKUMAR ;LEVY, BRUCE D ;MAUGER, DAVID T.;MEYERS, DEBORAH A.;MOORE, WENDY C;WENZEL, SALLY E;WOODRUFF, PRESCOTT G2019-09-23Immunometabolic phenotypes in adult severe asthma and disease progressionU01HL146002Principal InvestigatorAuthorship 12786681432795586Li X, Christenson SA, Modena B, Li H, Busse WW, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston B, Hastie AT, Israel E, Jarjour NN, Levy BD, Moore WC, Woodruff PG, Kaminski N, Wenzel SE, Bleecker ER, Meyers DAThe Journal of allergy and clinical immunologyGenetic analyses identify GSDMB associated with asthma severity, exacerbations, and antiviral pathways. J Allergy Clin Immunol. 2021 03; 147(3):894-909.J Allergy Clin Immunol2020-08-11T00:00:002020Genetic analyses identify GSDMB associated with asthma severity, exacerbations, and antiviral pathways.Authorship 12816302832873427Serhan CN, Gupta SK, Perretti M, Godson C, Brennan E, Li Y, Soehnlein O, Shimizu T, Werz O, Chiurchiù V, Azzi A, Dubourdeau M, Gupta SS, Schopohl P, Hoch M, Gjorgevikj D, Khan FM, Brauer D, Tripathi A, Cesnulevicius K, Lescheid D, Schultz M, Särndahl E, Repsilber D, Kruse R, Sala A, Haeggström JZ, Levy BD, Filep JG, Wolkenhauer OMolecular aspects of medicineWITHDRAWN: The Atlas of Inflammation Resolution (AIR). Mol Aspects Med. 2020 08 29; 100893.Mol Aspects Med2020-08-29T00:00:002020WITHDRAWN: The Atlas of Inflammation Resolution (AIR).Authorship 12862392832893032Serhan CN, Gupta SK, Perretti M, Godson C, Brennan E, Li Y, Soehnlein O, Shimizu T, Werz O, Chiurchiù V, Azzi A, Dubourdeau M, Gupta SS, Schopohl P, Hoch M, Gjorgevikj D, Khan FM, Brauer D, Tripathi A, Cesnulevicius K, Lescheid D, Schultz M, Särndahl E, Repsilber D, Kruse R, Sala A, Haeggström JZ, Levy BD, Filep JG, Wolkenhauer OMolecular aspects of medicineThe Atlas of Inflammation Resolution (AIR). Mol Aspects Med. 2020 08; 74:100894.Mol Aspects Med2020-09-03T00:00:002020The Atlas of Inflammation Resolution (AIR).Authorship 12910274Authorship 1290961532997914Anderson JD, Ho VT, Wright KT, Levy BD, Loscalzo JThe New England journal of medicineParroting Lymphoma. N Engl J Med. 2020 10 01; 383(14):1376-1381.N Engl J Med2020-10-01T00:00:002020Parroting Lymphoma.32990714Jeon H, Jundi B, Choi K, Ryu H, Levy BD, Lim G, Han JLab on a chipFully-automated and field-deployable blood leukocyte separation platform using multi-dimensional double spiral (MDDS) inertial microfluidics. Lab Chip. 2020 09 29; 20(19):3612-3624.Lab Chip2020-09-29T00:00:002020Fully-automated and field-deployable blood leukocyte separation platform using multi-dimensional double spiral (MDDS) inertial microfluidics.Authorship 129592710433057201Bick AG, Weinstock JS, Nandakumar SK, Fulco CP, Bao EL, Zekavat SM, Szeto MD, Liao X, Leventhal MJ, Nasser J, Chang K, Laurie C, Burugula BB, Gibson CJ, Lin AE, Taub MA, Aguet F, Ardlie K, Mitchell BD, Barnes KC, Moscati A, Fornage M, Redline S, Psaty BM, Silverman EK, Weiss ST, Palmer ND, Vasan RS, Burchard EG, Kardia SLR, He J, Kaplan RC, Smith NL, Arnett DK, Schwartz DA, Correa A, de Andrade M, Guo X, Konkle BA, Custer B, Peralta JM, Gui H, Meyers DA, McGarvey ST, Chen IY, Shoemaker MB, Peyser PA, Broome JG, Gogarten SM, Wang FF, Wong Q, Montasser ME, Daya M, Kenny EE, North KE, Launer LJ, Cade BE, Bis JC, Cho MH, Lasky-Su J, Bowden DW, Cupples LA, Mak ACY, Becker LC, Smith JA, Kelly TN, Aslibekyan S, Heckbert SR, Tiwari HK, Yang IV, Heit JA, Lubitz SA, Johnsen JM, Curran JE, Wenzel SE, Weeks DE, Rao DC, Darbar D, Moon JY, Tracy RP, Buth EJ, Rafaels N, Loos RJF, Durda P, Liu Y, Hou L, Lee J, Kachroo P, Freedman BI, Levy D, Bielak LF, Hixson JE, Floyd JS, Whitsel EA, Ellinor PT, Irvin MR, Fingerlin TE, Raffield LM, Armasu SM, Wheeler MM, Sabino EC, Blangero J, Williams LK, Levy BD, Sheu WH, Roden DM, Boerwinkle E, Manson JE, Mathias RA, Desai P, Taylor KD, Johnson AD, Auer PL, Kooperberg C, Laurie CC, Blackwell TW, Smith AV, Zhao H, Lange E, Lange L, Rich SS, Rotter JI, Wilson JG, Scheet P, Kitzman JO, Lander ES, Engreitz JM, Ebert BL, Reiner AP, Jaiswal S, Abecasis G, Sankaran VG, Kathiresan S, Natarajan PNatureInherited causes of clonal haematopoiesis in 97,691 whole genomes. Nature. 2020 10; 586(7831):763-768.Nature2020-10-14T00:00:002020Inherited causes of clonal haematopoiesis in 97,691 whole genomes.true1Associate Professor of MedicineAssociate Professor of MedicineAuthorship 1307537533134939Tejera P, Abdulnour RE, Zhu Z, Su L, Levy BD, Christiani DCCritical care explorationsPlasma Levels of Proresolving and Prophlogistic Lipid Mediators: Association With Severity of Respiratory Failure and Mortality in Acute Respiratory Distress Syndrome. Crit Care Explor. 2020 Oct; 2(10):e0241.Crit Care Explor2020-10-12T00:00:002020Plasma Levels of Proresolving and Prophlogistic Lipid Mediators: Association With Severity of Respiratory Failure and Mortality in Acute Respiratory Distress Syndrome.33290668Denlinger LC, Phillips BR, Sorkness RL, Bleecker ER, Castro M, DeBoer MD, Fitzpatrick AM, Hastie AT, Gaffin JM, Moore WC, Peters MC, Peters SP, Phipatanakul W, Cardet JC, Erzurum SC, Fahy JV, Fajt ML, Gaston B, Levy BD, Meyers DA, Ross K, Teague WG, Wenzel SE, Woodruff PG, Zein J, Jarjour NN, Mauger DT, Israel EAmerican journal of respiratory and critical care medicineResponsiveness to Parenteral Corticosteroids and Lung Function Trajectory in Adults with Moderate-to-Severe Asthma. Am J Respir Crit Care Med. 2021 04 01; 203(7):841-852.Am J Respir Crit Care Med2021-04-01T00:00:002021Responsiveness to Parenteral Corticosteroids and Lung Function Trajectory in Adults with Moderate-to-Severe Asthma.Authorship 131248519Authorship 13221082133453289Crosson T, Wang JC, Doyle B, Merrison H, Balood M, Parrin A, Pascal M, Mindt BC, Seehus CR, Ozcan A, Huang X, Semenara E, Lai NYY, Majdoubi A, Abdulnour RE, Rajchgot T, Rafei M, Foster SL, Thibodeau J, Fritz JH, Levy BD, Woolf CJ, Talbot SThe Journal of allergy and clinical immunologyFceR1-expressing nociceptors trigger allergic airway inflammation. J Allergy Clin Immunol. 2021 06; 147(6):2330-2342.J Allergy Clin Immunol2021-01-13T00:00:002021FceR1-expressing nociceptors trigger allergic airway inflammation.Authorship 1568553Authorship 1325849833545021Hastie AT, Mauger DT, Denlinger LC, Coverstone A, Castro M, Erzurum S, Jarjour N, Levy BD, Meyers DA, Moore WC, Phillips BR, Wenzel SE, Fahy JV, Israel E, Bleecker ERAmerican journal of respiratory and critical care medicineMixed Sputum Granulocyte Longitudinal Impact on Lung Function in the Severe Asthma Research Program. Am J Respir Crit Care Med. 2021 04 01; 203(7):882-892.Am J Respir Crit Care Med2021-04-01T00:00:002021Mixed Sputum Granulocyte Longitudinal Impact on Lung Function in the Severe Asthma Research Program.Authorship 1335332433657298Jilg N, Lau ES, Baker MA, Levy BD, Loscalzo JThe New England journal of medicineA Treacherous Course. N Engl J Med. 2021 Mar 04; 384(9):860-865.N Engl J Med2021-03-04T00:00:002021A Treacherous Course.Authorship 133758410533707633Bick AG, Weinstock JS, Nandakumar SK, Fulco CP, Bao EL, Zekavat SM, Szeto MD, Liao X, Leventhal MJ, Nasser J, Chang K, Laurie C, Burugula BB, Gibson CJ, Niroula A, Lin AE, Taub MA, Aguet F, Ardlie K, Mitchell BD, Barnes KC, Moscati A, Fornage M, Redline S, Psaty BM, Silverman EK, Weiss ST, Palmer ND, Vasan RS, Burchard EG, Kardia SLR, He J, Kaplan RC, Smith NL, Arnett DK, Schwartz DA, Correa A, de Andrade M, Guo X, Konkle BA, Custer B, Peralta JM, Gui H, Meyers DA, McGarvey ST, Chen IY, Shoemaker MB, Peyser PA, Broome JG, Gogarten SM, Wang FF, Wong Q, Montasser ME, Daya M, Kenny EE, North KE, Launer LJ, Cade BE, Bis JC, Cho MH, Lasky-Su J, Bowden DW, Cupples LA, Mak ACY, Becker LC, Smith JA, Kelly TN, Aslibekyan S, Heckbert SR, Tiwari HK, Yang IV, Heit JA, Lubitz SA, Johnsen JM, Curran JE, Wenzel SE, Weeks DE, Rao DC, Darbar D, Moon JY, Tracy RP, Buth EJ, Rafaels N, Loos RJF, Durda P, Liu Y, Hou L, Lee J, Kachroo P, Freedman BI, Levy D, Bielak LF, Hixson JE, Floyd JS, Whitsel EA, Ellinor PT, Irvin MR, Fingerlin TE, Raffield LM, Armasu SM, Wheeler MM, Sabino EC, Blangero J, Williams LK, Levy BD, Sheu WH, Roden DM, Boerwinkle E, Manson JE, Mathias RA, Desai P, Taylor KD, Johnson AD, Auer PL, Kooperberg C, Laurie CC, Blackwell TW, Smith AV, Zhao H, Lange E, Lange L, Rich SS, Rotter JI, Wilson JG, Scheet P, Kitzman JO, Lander ES, Engreitz JM, Ebert BL, Reiner AP, Jaiswal S, Abecasis G, Sankaran VG, Kathiresan S, Natarajan PNatureAuthor Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes. Nature. 2021 Mar; 591(7851):E27.Nature2021-03-01T00:00:002021Author Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes.Authorship 159140333758891Oelsner EC, Allen NB, Ali T, Anugu P, Andrews H, Asaro A, Balte PP, Barr RG, Bertoni AG, Bon J, Boyle R, Chang AA, Chen G, Cole SA, Coresh J, Cornell E, Correa A, Couper D, Cushman M, Demmer RT, Elkind MSV, Folsom AR, Fretts AM, Gabriel KP, Gallo L, Gutierrez J, Han MK, Henderson JM, Howard VJ, Isasi CR, Jacobs DR, Judd SE, Mukaz DK, Kanaya AM, Kandula NR, Kaplan R, Krishnaswamy A, Kinney GL, Kucharska-Newton A, Lee JS, Lewis CE, Levine DA, Levitan EB, Levy B, Make B, Malloy K, Manly JJ, Meyer KA, Min YI, Moll M, Moore WC, Mauger D, Ortega VE, Palta P, Parker MM, Phipatanakul W, Post W, Psaty BM, Regan EA, Ring K, Roger VL, Rotter JI, Rundek T, Sacco RL, Schembri M, Schwartz DA, Seshadri S, Shikany JM, Sims M, Hinckley Stukovsky KD, Talavera GA, Tracy RP, Umans JG, Vasan RS, Watson K, Wenzel SE, Winters K, Woodruff PG, Xanthakis V, Zhang Y, Zhang YmedRxiv : the preprint server for health sciencesCollaborative Cohort of Cohorts for COVID-19 Research (C4R) Study: Study Design. medRxiv. 2021 Mar 20.medRxiv2021-03-20T00:00:002021Collaborative Cohort of Cohorts for COVID-19 Research (C4R) Study: Study Design.Authorship 134257544Authorship 13436862033779531Zein JG, McManus JM, Sharifi N, Erzurum SC, Marozkina N, Lahm T, Giddings O, Davis MD, DeBoer MD, Comhair SA, Bazeley P, Kim HJ, Busse W, Calhoun W, Castro M, Chung KF, Fahy JV, Israel E, Jarjour NN, Levy BD, Mauger DT, Moore WC, Ortega VE, Peters M, Bleecker ER, Meyers DA, Zhao Y, Wenzel SE, Gaston BAmerican journal of respiratory and critical care medicineBenefits of Airway Androgen Receptor Expression in Human Asthma. Am J Respir Crit Care Med. 2021 08 01; 204(3):285-293.Am J Respir Crit Care Med2021-08-01T00:00:002021Benefits of Airway Androgen Receptor Expression in Human Asthma.33883027Kasela S, Ortega VE, Martorella M, Garudadri S, Nguyen J, Ampleford E, Pasanen A, Nerella S, Buschur KL, Barjaktarevic IZ, Barr RG, Bleecker ER, Bowler RP, Comellas AP, Cooper CB, Couper DJ, Criner GJ, Curtis JL, Han MK, Hansel NN, Hoffman EA, Kaner RJ, Krishnan JA, Martinez FJ, McDonald MN, Meyers DA, Paine R, Peters SP, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Israel E, Jarjour NN, Levy BD, Li X, Moore WC, Wenzel SE, Zein J, Langelier C, Woodruff PG, Lappalainen T, Christenson SAGenome medicineGenetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium. Genome Med. 2021 04 21; 13(1):66.Genome Med2021-04-21T00:00:002021Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium.Authorship 134910735Authorship 13553261233988876Tochitsky I, Jo S, Andrews N, Kotoda M, Doyle B, Shim J, Talbot S, Roberson D, Lee J, Haste L, Jordan SM, Levy BD, Bean BP, Woolf CJBritish journal of pharmacologyInhibition of inflammatory pain and cough by a novel charged sodium channel blocker. Br J Pharmacol. 2021 10; 178(19):3905-3923.Br J Pharmacol2021-06-21T00:00:002021Inhibition of inflammatory pain and cough by a novel charged sodium channel blocker.Authorship 13710612Authorship 13718371134166226Jundi B, Lee DH, Jeon H, Duvall MG, Nijmeh J, Abdulnour RE, Pinilla-Vera M, Baron RM, Han J, Voldman J, Levy BDJCI insightInflammation resolution circuits are uncoupled in acute sepsis and correlate with clinical severity. JCI Insight. 2021 08 09; 6(15).JCI Insight2021-08-09T00:00:002021Inflammation resolution circuits are uncoupled in acute sepsis and correlate with clinical severity.34176102Nijmeh J, Levy BDCell biochemistry and biophysicsLipid-Derived Mediators are Pivotal to Leukocyte and Lung Cell Responses in Sepsis and ARDS. Cell Biochem Biophys. 2021 Sep; 79(3):449-459.Cell Biochem Biophys2021-06-27T00:00:002021Lipid-Derived Mediators are Pivotal to Leukocyte and Lung Cell Responses in Sepsis and ARDS.Authorship 1392662634489955Walker KH, Krishnamoorthy N, Brüggemann TR, Shay AE, Serhan CN, Levy BDFrontiers in immunologyProtectins PCTR1 and PD1 Reduce Viral Load and Lung Inflammation During Respiratory Syncytial Virus Infection in Mice. Front Immunol. 2021; 12:704427.Front Immunol2021-08-19T00:00:002021Protectins PCTR1 and PD1 Reduce Viral Load and Lung Inflammation During Respiratory Syncytial Virus Infection in Mice.Authorship 1422758434954726Cagnina RE, Duvall MG, Nijmeh J, Levy BDCurrent opinion in clinical nutrition and metabolic careSpecialized pro-resolving mediators in respiratory diseases. Curr Opin Clin Nutr Metab Care. 2022 03 01; 25(2):67-74.Curr Opin Clin Nutr Metab Care2022-03-01T00:00:002022Specialized pro-resolving mediators in respiratory diseases.Authorship 143054720Authorship 1430733534405339Salerno BS, Pereira ABM, de Souza HI, Silva-Vergara ML, Levy BD, Rogerio APInflammopharmacologyAnti-inflammatory actions of aspirin-triggered resolvin D1 (AT-RvD1) in bronchial epithelial cells infected with Cryptococcus neoformans. Inflammopharmacology. 2021 Oct; 29(5):1603-1612.Inflammopharmacology2021-08-17T00:00:002021Anti-inflammatory actions of aspirin-triggered resolvin D1 (AT-RvD1) in bronchial epithelial cells infected with Cryptococcus neoformans.35104436Tang M, Elicker BM, Henry T, Gierada DS, Schiebler ML, Huang BK, Peters MC, Castro M, Hoffman EA, Fain SB, Ash SY, Choi J, Hall C, Phillips BR, Mauger DT, Denlinger LC, Jarjour NN, Israel E, Phipatanakul W, Levy BD, Wenzel SE, Bleecker ER, Woodruff PG, Fahy JV, Dunican EMAmerican journal of respiratory and critical care medicineMucus Plugs Persist in Asthma, and Changes in Mucus Plugs Associate with Changes in Airflow over Time. Am J Respir Crit Care Med. 2022 05 01; 205(9):1036-1045.Am J Respir Crit Care Med2022-05-01T00:00:002022Mucus Plugs Persist in Asthma, and Changes in Mucus Plugs Associate with Changes in Airflow over Time.35279711Oelsner EC, Krishnaswamy A, Balte PP, Allen NB, Ali T, Anugu P, Andrews HF, Arora K, Asaro A, Barr RG, Bertoni AG, Bon J, Boyle R, Chang AA, Chen G, Coady S, Cole SA, Coresh J, Cornell E, Correa A, Couper D, Cushman M, Demmer RT, Elkind MSV, Folsom AR, Fretts AM, Gabriel KP, Gallo LC, Gutierrez J, Han MLK, Henderson JM, Howard VJ, Isasi CR, Jacobs DR, Judd SE, Mukaz DK, Kanaya AM, Kandula NR, Kaplan RC, Kinney GL, Kucharska-Newton A, Lee JS, Lewis CE, Levine DA, Levitan EB, Levy BD, Make BJ, Malloy K, Manly JJ, Mendoza-Puccini C, Meyer KA, Min YN, Moll MR, Moore WC, Mauger D, Ortega VE, Palta P, Parker MM, Phipatanakul W, Post WS, Postow L, Psaty BM, Regan EA, Ring K, Roger VL, Rotter JI, Rundek T, Sacco RL, Schembri M, Schwartz DA, Seshadri S, Shikany JM, Sims M, Hinckley Stukovsky KD, Talavera GA, Tracy RP, Umans JG, Vasan RS, Watson KE, Wenzel SE, Winters K, Woodruff PG, Xanthakis V, Zhang Y, Zhang YAmerican journal of epidemiologyCollaborative Cohort of Cohorts for COVID-19 Research (C4R) Study: Study Design. Am J Epidemiol. 2022 06 27; 191(7):1153-1173.Am J Epidemiol2022-06-27T00:00:002022Collaborative Cohort of Cohorts for COVID-19 Research (C4R) Study: Study Design.Authorship 143991246Authorship 14417308Authorship 1437217535353673Guo F, Hao Y, Zhang L, Croteau-Chonka DC, Thibault D, Kothari P, Li L, Levy BD, Zhou X, Raby BAAmerican journal of respiratory cell and molecular biologyAsthma Susceptibility Gene ORMDL3 Promotes Autophagy in Human Bronchial Epithelium. Am J Respir Cell Mol Biol. 2022 06; 66(6):661-670.Am J Respir Cell Mol Biol2022-06-01T00:00:002022Asthma Susceptibility Gene ORMDL3 Promotes Autophagy in Human Bronchial Epithelium.35278626Puzzovio PG, Brüggemann TR, Pahima H, Mankuta D, Levy BD, Levi-Schaffer FPharmacological researchCromolyn Sodium differentially regulates human mast cell and mouse leukocyte responses to control allergic inflammation. Pharmacol Res. 2022 04; 178:106172.Pharmacol Res2022-03-09T00:00:002022Cromolyn Sodium differentially regulates human mast cell and mouse leukocyte responses to control allergic inflammation.Authorship 2835574Authorship 144442517Authorship 144652520Authorship 14461711935471111Trivedi AP, Hall C, Goss CW, Lew D, Krings JG, McGregor MC, Samant M, Sieren JP, Li H, Schechtman KB, Schirm J, McEleney S, Peterson S, Moore WC, Bleecker ER, Meyers DA, Israel E, Washko GR, Levy BD, Leader JK, Wenzel SE, Fahy JV, Schiebler ML, Fain SB, Jarjour NN, Mauger DT, Reinhardt JM, Newell JD, Hoffman EA, Castro M, Sheshadri ARadiologyQuantitative CT Characteristics of Cluster Phenotypes in the Severe Asthma Research Program Cohorts. Radiology. 2022 08; 304(2):450-459.Radiology2022-04-26T00:00:002022Quantitative CT Characteristics of Cluster Phenotypes in the Severe Asthma Research Program Cohorts.35451201Izquierdo ME, Marion CR, Moore WC, Raraigh KS, Taylor-Cousar JL, Cutting GR, Ampleford E, Hawkins GA, Zein J, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Israel E, Jarjour NN, Mauger D, Levy BD, Wenzel SE, Woodruff P, Bleecker ER, Meyers DA, Ortega VEPediatric pulmonologyDNA sequencing analysis of cystic fibrosis transmembrane conductance regulator gene identifies cystic fibrosis-associated variants in the Severe Asthma Research Program. Pediatr Pulmonol. 2022 07; 57(7):1782-1788.Pediatr Pulmonol2022-05-05T00:00:002022DNA sequencing analysis of cystic fibrosis transmembrane conductance regulator gene identifies cystic fibrosis-associated variants in the Severe Asthma Research Program.35379853Herrera VLM, Walkey AJ, Nguyen MQ, Gromisch CM, Mosaddhegi JZ, Gromisch MS, Jundi B, Lukassen S, Carstensen S, Denis R, Belkina AC, Baron RM, Pinilla-Vera M, Mueller M, Kimberly WT, Goldstein JN, Lehmann I, Shih AR, Eils R, Levy BD, Ruiz-Opazo NScientific reportsA targetable 'rogue' neutrophil-subset, [CD11b+DEspR+] immunotype, is associated with severity and mortality in acute respiratory distress syndrome (ARDS) and COVID-19-ARDS. Sci Rep. 2022 04 04; 12(1):5583.Sci Rep2022-04-04T00:00:002022A targetable 'rogue' neutrophil-subset, [CD11b+DEspR+] immunotype, is associated with severity and mortality in acute respiratory distress syndrome (ARDS) and COVID-19-ARDS.Authorship 14664511635687105Peters MC, Schiebler ML, Cardet JC, Johansson MW, Sorkness R, DeBoer MD, Bleecker ER, Meyers DA, Castro M, Sumino K, Erzurum SC, Tattersall MC, Zein JG, Hastie AT, Moore W, Levy BD, Israel E, Phillips BR, Mauger DT, Wenzel SE, Fajt ML, Koliwad SK, Denlinger LC, Woodruff PG, Jarjour NN, Fahy JVAmerican journal of respiratory and critical care medicineThe Impact of Insulin Resistance on Loss of Lung Function and Response to Treatment in Asthma. Am J Respir Crit Care Med. 2022 11 01; 206(9):1096-1106.Am J Respir Crit Care Med2022-11-01T00:00:002022The Impact of Insulin Resistance on Loss of Lung Function and Response to Treatment in Asthma.36322848Lipsyc-Sharf M, Connell NT, Ostrominski JW, Levy BD, Loscalzo JThe New England journal of medicineA Shear Decline. N Engl J Med. 2022 11 03; 387(18):1700-1706.N Engl J Med2022-11-03T00:00:002022A Shear Decline.Authorship 149851512Authorship 148566314Authorship 15025994Authorship 14792074Authorship 150162514Authorship 14873161036194556Tattersall MC, Lee KE, Tsuchiya N, Osman F, Korcarz CE, Hansen KM, Peters MC, Fahy JV, Longhurst CA, Dunican E, Wentzel SE, Leader JK, Israel E, Levy BD, Castro M, Erzurum SC, Lempel J, Moore WC, Bleecker ER, Phillips BR, Mauger DT, Hoffman EA, Fain SB, Reeder SB, Sorkness RL, Jarjour NN, Denlinger LC, Schiebler MLAmerican journal of respiratory and critical care medicineSkeletal Muscle Adiposity and Lung Function Trajectory in the Severe Asthma Research Program. Am J Respir Crit Care Med. 2023 02 15; 207(4):475-484.Am J Respir Crit Care Med2023-02-15T00:00:002023Skeletal Muscle Adiposity and Lung Function Trajectory in the Severe Asthma Research Program.35921455Chen HX, Cernadas M, Vargas SO, Levy BD, Loscalzo JThe New England journal of medicineDiagnostic Aspirations. N Engl J Med. 2022 08 04; 387(5):452-458.N Engl J Med2022-08-04T00:00:002022Diagnostic Aspirations.36238896Brüggemann TR, Carlo T, Krishnamoorthy N, Duvall MG, Abdulnour RE, Nijmeh J, Peh HY, Filippakis H, Croze RH, Goh B, Oh SF, Levy BDiScienceMouse phospholipid phosphatase 6 regulates dendritic cell cholesterol, macropinocytosis, and allergen sensitization. iScience. 2022 Oct 21; 25(10):105185.iScience2022-09-23T00:00:002022Mouse phospholipid phosphatase 6 regulates dendritic cell cholesterol, macropinocytosis, and allergen sensitization.36066606Li X, Guerra S, Ledford JG, Kraft M, Li H, Hastie AT, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston B, Israel E, Jarjour NN, Levy BD, Mauger DT, Moore WC, Zein J, Kaminski N, Wenzel SE, Woodruff PG, Meyers DA, Bleecker ERAmerican journal of respiratory and critical care medicineLow CC16 mRNA Expression Levels in Bronchial Epithelial Cells Are Associated with Asthma Severity. Am J Respir Crit Care Med. 2023 02 15; 207(4):438-451.Am J Respir Crit Care Med2023-02-15T00:00:002023Low CC16 mRNA Expression Levels in Bronchial Epithelial Cells Are Associated with Asthma Severity.35913160P Tavares L, Brüggemann TR, M Rezende R, G Machado M, Cagnina RE, Shay AE, C Garcia C, Nijmeh J, M Teixeira M, Levy BDmBioCysteinyl Maresins Reprogram Macrophages to Protect Mice from Streptococcus pneumoniae after Influenza A Virus Infection. mBio. 2022 08 30; 13(4):e0126722.mBio2022-08-01T00:00:002022Cysteinyl Maresins Reprogram Macrophages to Protect Mice from Streptococcus pneumoniae after Influenza A Virus Infection.Authorship 44639210Authorship 15042201336386765Wada N, Li Y, Hino T, Gagne S, Valtchinov VI, Gay E, Nishino M, Madore B, Guttmann CRG, Bond S, Ishigami K, Hunninghake GM, Levy BD, Kaye KM, Christiani DC, Hatabu HEuropean journal of radiology openCOVID-19 Vaccination reduced pneumonia severity. Eur J Radiol Open. 2022; 9:100456.Eur J Radiol Open2022-11-11T00:00:002022COVID-19 Vaccination reduced pneumonia severity.Authorship 2031902Authorship 15119781236595677Krishnamoorthy N, Walker KH, Brüggemann TR, Tavares LP, Smith EW, Nijmeh J, Bai Y, Ai X, Cagnina RE, Duvall MG, Lehoczky JA, Levy BDProceedings of the National Academy of Sciences of the United States of AmericaThe Maresin 1-LGR6 axis decreases respiratory syncytial virus-induced lung inflammation. Proc Natl Acad Sci U S A. 2023 01 10; 120(2):e2206480120.Proc Natl Acad Sci U S A2023-01-03T00:00:002023The Maresin 1-LGR6 axis decreases respiratory syncytial virus-induced lung inflammation.36724332Coraor Fried J, Ross JJ, Weiss ZF, Levy BD, Loscalzo JThe New England journal of medicineA Breathtaking Discovery. N Engl J Med. 2023 02 02; 388(5):454-459.N Engl J Med2023-02-02T00:00:002023A Breathtaking Discovery.Authorship 15216324Authorship 15261057Authorship 15242581736773709Puzzovio PG, Pahima H, George T, Mankuta D, Eliashar R, Tiligada E, Levy BD, Levi-Schaffer FPharmacological researchMast cells contribute to the resolution of allergic inflammation by releasing resolvin D1. Pharmacol Res. 2023 03; 189:106691.Pharmacol Res2023-02-10T00:00:002023Mast cells contribute to the resolution of allergic inflammation by releasing resolvin D1.36796454Ginebaugh SP, Hagner M, Ray A, Erzurum SC, Comhair SAA, Denlinger LC, Jarjour NN, Castro M, Woodruff PG, Christenson SA, Bleecker ER, Meyers DA, Hastie AT, Moore WC, Mauger DT, Israel E, Levy BD, Wenzel SE, Camiolo MJThe Journal of allergy and clinical immunologyBronchial epithelial cell transcriptional responses to inhaled corticosteroids dictate severe asthmatic outcomes. J Allergy Clin Immunol. 2023 06; 151(6):1513-1524.J Allergy Clin Immunol2023-02-14T00:00:002023Bronchial epithelial cell transcriptional responses to inhaled corticosteroids dictate severe asthmatic outcomes.36856620Ostrominski JW, Clancy TE, Bry L, Levy BD, Loscalzo JThe New England journal of medicineA Rocky Resurgence. N Engl J Med. 2023 Mar 02; 388(9):834-839.N Engl J Med2023-03-02T00:00:002023A Rocky Resurgence.Authorship 15290924Authorship 153054518Authorship 15329262Authorship 15321281436883046Hino T, Nishino M, Valtchinov VI, Gagne S, Gay E, Wada N, Tseng SC, Madore B, Guttmann CRG, Ishigami K, Li Y, Christiani DC, Hunninghake GM, Levy BD, Kaye KM, Hatabu HEuropean journal of radiology openSevere COVID-19 pneumonia leads to post-COVID-19 lung abnormalities on follow-up CT scans. Eur J Radiol Open. 2023; 10:100483.Eur J Radiol Open2023-03-03T00:00:002023Severe COVID-19 pneumonia leads to post-COVID-19 lung abnormalities on follow-up CT scans.36893862Gauthier M, Kale SL, Oriss TB, Gorry M, Ramonell RP, Dalton K, Ray P, Fahy JV, Seibold MA, Castro M, Jarjour N, Gaston B, Bleecker ER, Meyers DA, Moore W, Hastie AT, Israel E, Levy BD, Mauger D, Erzurum S, Comhair SA, Wenzel SE, Ray AThe Journal of allergy and clinical immunologyCCL5 is a potential bridge between type 1 and type 2 inflammation in asthma. J Allergy Clin Immunol. 2023 07; 152(1):94-106.e12.J Allergy Clin Immunol2023-03-08T00:00:002023CCL5 is a potential bridge between type 1 and type 2 inflammation in asthma.36928079Puzzovio PG, Levy BD, Levi-Schaffer FInternational archives of allergy and immunologyCD300a Regulates Mouse Macrophage Functionality in Allergic Inflammation. Int Arch Allergy Immunol. 2023; 184(7):720-726.Int Arch Allergy Immunol2023-03-16T00:00:002023CD300a Regulates Mouse Macrophage Functionality in Allergic Inflammation.Authorship 1921521Authorship 2004466Authorship 4828341237278994Thaweethai T, Jolley SE, Karlson EW, Levitan EB, Levy B, McComsey GA, McCorkell L, Nadkarni GN, Parthasarathy S, Singh U, Walker TA, Selvaggi CA, Shinnick DJ, Schulte CCM, Atchley-Challenner R, Alba GA, Alicic R, Altman N, Anglin K, Argueta U, Ashktorab H, Baslet G, Bassett IV, Bateman L, Bedi B, Bhattacharyya S, Bind MA, Blomkalns AL, Bonilla H, Bush PA, Castro M, Chan J, Charney AW, Chen P, Chibnik LB, Chu HY, Clifton RG, Costantine MM, Cribbs SK, Davila Nieves SI, Deeks SG, Duven A, Emery IF, Erdmann N, Erlandson KM, Ernst KC, Farah-Abraham R, Farner CE, Feuerriegel EM, Fleurimont J, Fonseca V, Franko N, Gainer V, Gander JC, Gardner EM, Geng LN, Gibson KS, Go M, Goldman JD, Grebe H, Greenway FL, Habli M, Hafner J, Han JE, Hanson KA, Heath J, Hernandez C, Hess R, Hodder SL, Hoffman MK, Hoover SE, Huang B, Hughes BL, Jagannathan P, John J, Jordan MR, Katz SD, Kaufman ES, Kelly JD, Kelly SW, Kemp MM, Kirwan JP, Klein JD, Knox KS, Krishnan JA, Kumar A, Laiyemo AO, Lambert AA, Lanca M, Lee-Iannotti JK, Logarbo BP, Longo MT, Luciano CA, Lutrick K, Maley JH, Marathe JG, Marconi V, Marshall GD, Martin CF, Matusov Y, Mehari A, Mendez-Figueroa H, Mermelstein R, Metz TD, Morse R, Mosier J, Mouchati C, Mullington J, Murphy SN, Neuman RB, Nikolich JZ, Ofotokun I, Ojemakinde E, Palatnik A, Palomares K, Parimon T, Parry S, Patterson JE, Patterson TF, Patzer RE, Peluso MJ, Pemu P, Pettker CM, Plunkett BA, Pogreba-Brown K, Poppas A, Quigley JG, Reddy U, Reece R, Reeder H, Reeves WB, Reiman EM, Rischard F, Rosand J, Rouse DJ, Ruff A, Saade G, Sandoval GJ, Schlater SM, Shepherd F, Sherif ZA, Simhan H, Singer NG, Skupski DW, Sowles A, Sparks JA, Sukhera FI, Taylor BS, Teunis L, Thomas RJ, Thorp JM, Thuluvath P, Ticotsky A, Tita AT, Tuttle KR, Urdaneta AE, Valdivieso D, VanWagoner TM, Vasey A, Verduzco-Gutierrez M, Wallace ZS, Ward HD, Warren DE, Weiner SJ, Welch S, Whiteheart SW, Wiley Z, Wisnivesky JP, Yee LM, Zisis S, Horwitz LI, Foulkes ASJAMADevelopment of a Definition of Postacute Sequelae of SARS-CoV-2 Infection. JAMA. 2023 06 13; 329(22):1934-1946.JAMA2023-06-13T00:00:002023Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection.Authorship 2038362Authorship 1572712100Authorship 1569554537352211Horwitz LI, Thaweethai T, Brosnahan SB, Cicek MS, Fitzgerald ML, Goldman JD, Hess R, Hodder SL, Jacoby VL, Jordan MR, Krishnan JA, Laiyemo AO, Metz TD, Nichols L, Patzer RE, Sekar A, Singer NG, Stiles LE, Taylor BS, Ahmed S, Algren HA, Anglin K, Aponte-Soto L, Ashktorab H, Bassett IV, Bedi B, Bhadelia N, Bime C, Bind MC, Black LJ, Blomkalns AL, Brim H, Castro M, Chan J, Charney AW, Chen BK, Chen LQ, Chen P, Chestek D, Chibnik LB, Chow DC, Chu HY, Clifton RG, Collins S, Costantine MM, Cribbs SK, Deeks SG, Dickinson JD, Donohue SE, Durstenfeld MS, Emery IF, Erlandson KM, Facelli JC, Farah-Abraham R, Finn AV, Fischer MS, Flaherman VJ, Fleurimont J, Fonseca V, Gallagher EJ, Gander JC, Gennaro ML, Gibson KS, Go M, Goodman SN, Granger JP, Greenway FL, Hafner JW, Han JE, Harkins MS, Hauser KSP, Heath JR, Hernandez CR, Ho O, Hoffman MK, Hoover SE, Horowitz CR, Hsu H, Hsue PY, Hughes BL, Jagannathan P, James JA, John J, Jolley S, Judd SE, Juskowich JJ, Kanjilal DG, Karlson EW, Katz SD, Kelly JD, Kelly SW, Kim AY, Kirwan JP, Knox KS, Kumar A, Lamendola-Essel MF, Lanca M, Lee-Lannotti JK, Lefebvre RC, Levy BD, Lin JY, Logarbo BP, Logue JK, Longo MT, Luciano CA, Lutrick K, Malakooti SK, Mallett G, Maranga G, Marathe JG, Marconi VC, Marshall GD, Martin CF, Martin JN, May HT, McComsey GA, McDonald D, Mendez-Figueroa H, Miele L, Mittleman MA, Mohandas S, Mouchati C, Mullington JM, Nadkarni GN, Nahin ER, Neuman RB, Newman LT, Nguyen A, Nikolich JZ, Ofotokun I, Ogbogu PU, Palatnik A, Palomares KTS, Parimon T, Parry S, Parthasarathy S, Patterson TF, Pearman A, Peluso MJ, Pemu P, Pettker CM, Plunkett BA, Pogreba-Brown K, Poppas A, Porterfield JZ, Quigley JG, Quinn DK, Raissy H, Rebello CJ, Reddy UM, Reece R, Reeder HT, Rischard FP, Rosas JM, Rosen CJ, Rouphael NG, Rouse DJ, Ruff AM, Saint Jean C, Sandoval GJ, Santana JL, Schlater SM, Sciurba FC, Selvaggi C, Seshadri S, Sesso HD, Shah DP, Shemesh E, Sherif ZA, Shinnick DJ, Simhan HN, Singh U, Sowles A, Subbian V, Sun J, Suthar MS, Teunis LJ, Thorp JM, Ticotsky A, Tita ATN, Tragus R, Tuttle KR, Urdaneta AE, Utz PJ, VanWagoner TM, Vasey A, Vernon SD, Vidal C, Walker T, Ward HD, Warren DE, Weeks RM, Weiner SJ, Weyer JC, Wheeler JL, Whiteheart SW, Wiley Z, Williams NJ, Wisnivesky JP, Wood JC, Yee LM, Young NM, Zisis SN, Foulkes ASPloS oneResearching COVID to Enhance Recovery (RECOVER) adult study protocol: Rationale, objectives, and design. PLoS One. 2023; 18(6):e0286297.PLoS One2023-06-23T00:00:002023Researching COVID to Enhance Recovery (RECOVER) adult study protocol: Rationale, objectives, and design.true1Research Associate in MedicineResearch Associate in Medicine37552821Brüggemann TR, Peh HY, Tavares LP, Nijmeh J, Shay AE, Rezende RM, Lanser TB, Serhan CN, Levy BDAmerican journal of respiratory cell and molecular biologyEosinophil Phenotypes Are Functionally Regulated by Resolvin D2 during Allergic Lung Inflammation. Am J Respir Cell Mol Biol. 2023 12; 69(6):666-677.Am J Respir Cell Mol Biol2023-12-01T00:00:002023Eosinophil Phenotypes Are Functionally Regulated by Resolvin D2 during Allergic Lung Inflammation.Authorship 15934179true1George E. Thibault Academy Associate Professor of MedicineGeorge E. Thibault Academy Associate Professor of Medicinetrue1Samuel A. Levine Professor of Medicine; Hersey Distinguished Professor of the Theory and Practice of PhysicSamuel A. Levine Professor of Medicine; Hersey Distinguished Professor of the Theory and Practice of PhysicAuthorship 16012259Authorship 1603681337837390Tavares LP, Nijmeh J, Levy BDExperimental biology and medicine (Maywood, N.J.)Respiratory viral infection and resolution of inflammation: Roles for specialized pro-resolving mediators. Exp Biol Med (Maywood). 2023 10; 248(19):1635-1644.Exp Biol Med (Maywood)2023-10-14T00:00:002023Respiratory viral infection and resolution of inflammation: Roles for specialized pro-resolving mediators.37888888Peh HY, Brüggemann TR, Duvall MG, Nshimiyimana R, Nijmeh J, Cinelli MA, Israel E, Serhan CN, Levy BDAllergyResolvin D2 regulates type 2 inflammatory responses and promotes resolution of mouse allergic inflammation. Allergy. 2024 Mar; 79(3):739-743.Allergy2023-10-27T00:00:002023Resolvin D2 regulates type 2 inflammatory responses and promotes resolution of mouse allergic inflammation.2Head of the Department of Medicine at Brigham & Women's HospitalHead of the Department of Medicine at Brigham & Women's Hospitaltrue1Parker B. Francis Professor of MedicineParker B. Francis Professor of MedicineAuthorship 16092131338050198Wada N, Li Y, Gagne S, Hino T, Valtchinov VI, Gay E, Nishino M, Hammer MM, Madore B, Guttmann CRG, Ishigami K, Hunninghake GM, Levy BD, Kaye KM, Christiani DC, Hatabu HMedicineIncidence and severity of pulmonary embolism in COVID-19 infection: Ancestral, Alpha, Delta, and Omicron variants. Medicine (Baltimore). 2023 Dec 01; 102(48):e36417.Medicine (Baltimore)2023-12-01T00:00:002023Incidence and severity of pulmonary embolism in COVID-19 infection: Ancestral, Alpha, Delta, and Omicron variants.Authorship 161439112Authorship 16147571838127464Huang BK, Elicker BM, Henry TS, Kallianos KG, Hahn LD, Tang M, Heng F, McCulloch CE, Bhakta NR, Majumdar S, Choi J, Denlinger LC, Fain SB, Hastie AT, Hoffman EA, Israel E, Jarjour NN, Levy BD, Mauger DT, Sumino K, Wenzel SE, Castro M, Woodruff PG, Fahy JV, Sarp FTNSARPJCI insightPersistent mucus plugs in proximal airways are consequential for airflow limitation in asthma. JCI Insight. 2024 Feb 08; 9(3).JCI Insight2024-02-08T00:00:002024Persistent mucus plugs in proximal airways are consequential for airflow limitation in asthma.38113166Leung C, Tang M, Huang BK, Fain SB, Hoffman EA, Choi J, Dunican EM, Mauger DT, Denlinger LC, Jarjour NN, Israel E, Levy BD, Wenzel SE, Sumino K, Hastie AT, Schirm J, McCulloch CE, Peters MC, Woodruff PG, Sorkness RL, Castro M, Fahy JVAmerican journal of respiratory and critical care medicineA Novel Air Trapping Segment Score Identifies Opposing Effects of Obesity and Eosinophilia on Air Trapping in Asthma. Am J Respir Crit Care Med. 2023 Dec 19.Am J Respir Crit Care Med2023-12-19T00:00:002023A Novel Air Trapping Segment Score Identifies Opposing Effects of Obesity and Eosinophilia on Air Trapping in Asthma.Authorship 16229971038253462Hastie AT, Bishop AC, Khan MS, Bleecker ER, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Israel E, Levy BD, Mauger DT, Meyers DA, Moore WC, Ortega VE, Peters SP, Wenzel SE, Steele CHClinical and experimental allergy : journal of the British Society for Allergy and Clinical ImmunologyProtein-Protein interactive networks identified in bronchoalveolar lavage of severe compared to nonsevere asthma. Clin Exp Allergy. 2024 Jan 22.Clin Exp Allergy2024-01-22T00:00:002024Protein-Protein interactive networks identified in bronchoalveolar lavage of severe compared to nonsevere asthma.Authorship 1782232true1Assistant Professor of Medicine, Part-timeAssistant Professor of Medicine, Part-timeAuthorship 5384993true1Assistant Professor of AnaesthesiaAssistant Professor of Anaesthesiatrue1Professor of Emergency MedicineProfessor of Emergency Medicinetrue1S. Jean Emans, MD, Professor of PediatricsS. Jean Emans, MD, Professor of Pediatricstrue1Professor of MedicineProfessor of MedicineAuthorship 2466381Authorship 42557321NK159NandiniKrishnamoorthyNandini Krishnamoorthy, Ph.D.120681Krishnamoorthy, NandiniInstructor in MedicineAuthorship 6469082Authorship 6495895Authorship 6498918Authorship 663908323662178Sagliani KD, Dolnikowski GG, Hill NS, Fanburg BL, Levy BD, Preston IRPulmonary circulationDifferences between basal lung levels of select eicosanoids in rat and mouse. Pulm Circ. 2013 Jan; 3(1):82-8.Pulm Circ2013-01-01T00:00:002013Differences between basal lung levels of select eicosanoids in rat and mouse.23568778Carlo T, Kalwa H, Levy BDFASEB journal : official publication of the Federation of American Societies for Experimental Biology15-Epi-lipoxin A4 inhibits human neutrophil superoxide anion generation by regulating polyisoprenyl diphosphate phosphatase 1. FASEB J. 2013 Jul; 27(7):2733-41.FASEB J2013-04-08T00:00:00201315-Epi-lipoxin A4 inhibits human neutrophil superoxide anion generation by regulating polyisoprenyl diphosphate phosphatase 1.23730877Barnig C, Levy BDExpert review of clinical immunologyLipoxin A4: a new direction in asthma therapy? Expert Rev Clin Immunol. 2013 Jun; 9(6):491-3.Expert Rev Clin Immunol2013-06-01T00:00:002013Lipoxin A4: a new direction in asthma therapy?23627303Anthony D, Seow HJ, Uddin M, Thompson M, Dousha L, Vlahos R, Irving LB, Levy BD, Anderson GP, Bozinovski SAmerican journal of respiratory and critical care medicineSerum amyloid A promotes lung neutrophilia by increasing IL-17A levels in the mucosa and ?d T cells. Am J Respir Crit Care Med. 2013 Jul 15; 188(2):179-86.Am J Respir Crit Care Med2013-07-15T00:00:002013Serum amyloid A promotes lung neutrophilia by increasing IL-17A levels in the mucosa and ?d T cells.Authorship 5512528Authorship 6734068Authorship 677314124004126Levy BDThe New England journal of medicineSphingolipids and susceptibility to asthma. N Engl J Med. 2013 Sep 05; 369(10):976-8.N Engl J Med2013-09-05T00:00:002013Sphingolipids and susceptibility to asthma.23608729Kazani S, Planaguma A, Ono E, Bonini M, Zahid M, Marigowda G, Wechsler ME, Levy BD, Israel EThe Journal of allergy and clinical immunologyExhaled breath condensate eicosanoid levels associate with asthma and its severity. J Allergy Clin Immunol. 2013 Sep; 132(3):547-553.J Allergy Clin Immunol2013-04-19T00:00:002013Exhaled breath condensate eicosanoid levels associate with asthma and its severity.Authorship 3303832024395886Li C, Lee PS, Sun Y, Gu X, Zhang E, Guo Y, Wu CL, Auricchio N, Priolo C, Li J, Csibi A, Parkhitko A, Morrison T, Planaguma A, Kazani S, Israel E, Xu KF, Henske EP, Blenis J, Levy BD, Kwiatkowski D, Yu JJThe Journal of experimental medicineEstradiol and mTORC2 cooperate to enhance prostaglandin biosynthesis and tumorigenesis in TSC2-deficient LAM cells. J Exp Med. 2014 Jan 13; 211(1):15-28.J Exp Med2014-01-06T00:00:002014Estradiol and mTORC2 cooperate to enhance prostaglandin biosynthesis and tumorigenesis in TSC2-deficient LAM cells.Authorship 2398862Authorship 70380020Authorship 26636017Authorship 3138645Authorship 28667717Authorship 7187323Authorship 716950124313723Levy BD, Serhan CNAnnual review of physiologyResolution of acute inflammation in the lung. Annu Rev Physiol. 2014; 76:467-92.Annu Rev Physiol2013-12-02T00:00:002013Resolution of acute inflammation in the lung.24597870Hamnvik OP, Becker CB, Levy BD, Loscalzo JThe New England journal of medicineClinical problem-solving. Wasting away. N Engl J Med. 2014 Mar 06; 370(10):959-66.N Engl J Med2014-03-06T00:00:002014Clinical problem-solving. Wasting away.Authorship 967313Authorship 3064962Authorship 730900724659779Doyle JR, Krishnaji ST, Zhu G, Xu ZZ, Heller D, Ji RR, Levy BD, Kumar K, Kopin ASThe Journal of biological chemistryDevelopment of a membrane-anchored chemerin receptor agonist as a novel modulator of allergic airway inflammation and neuropathic pain. J Biol Chem. 2014 May 09; 289(19):13385-96.J Biol Chem2014-03-21T00:00:002014Development of a membrane-anchored chemerin receptor agonist as a novel modulator of allergic airway inflammation and neuropathic pain.Authorship 3085681Authorship 2700241Authorship 3492521Authorship 5468853Authorship 566253Authorship 760086325271607Hamnvik OP, Saldana F, Levy BD, Loscalzo JThe New England journal of medicineClinical problem-solving. Against the grain. N Engl J Med. 2014 Oct 02; 371(14):1333-8.N Engl J Med2014-10-02T00:00:002014Clinical problem-solving. Against the grain.Authorship 7637141925162465Ono E, Dutile S, Kazani S, Wechsler ME, Yang J, Hammock BD, Douda DN, Tabet Y, Khaddaj-Mallat R, Sirois M, Sirois C, Rizcallah E, Rousseau E, Martin R, Sutherland ER, Castro M, Jarjour NN, Israel E, Levy BDAmerican journal of respiratory and critical care medicineLipoxin generation is related to soluble epoxide hydrolase activity in severe asthma. Am J Respir Crit Care Med. 2014 Oct 15; 190(8):886-97.Am J Respir Crit Care Med2014-10-15T00:00:002014Lipoxin generation is related to soluble epoxide hydrolase activity in severe asthma.25359497Serhan CN, Chiang N, Dalli J, Levy BDCold Spring Harbor perspectives in biologyLipid mediators in the resolution of inflammation. Cold Spring Harb Perspect Biol. 2014 Oct 30; 7(2):a016311.Cold Spring Harb Perspect Biol2014-10-30T00:00:002014Lipid mediators in the resolution of inflammation.Emergency MedicineAuthorship 3740751Authorship 3773768Authorship 7716911025369934Abdulnour RE, Dalli J, Colby JK, Krishnamoorthy N, Timmons JY, Tan SH, Colas RA, Petasis NA, Serhan CN, Levy BDProceedings of the National Academy of Sciences of the United States of AmericaMaresin 1 biosynthesis during platelet-neutrophil interactions is organ-protective. Proc Natl Acad Sci U S A. 2014 Nov 18; 111(46):16526-31.Proc Natl Acad Sci U S A2014-11-04T00:00:002014Maresin 1 biosynthesis during platelet-neutrophil interactions is organ-protective.Authorship 4358503Authorship 44478017Authorship 572375425539814Krishnamoorthy N, Burkett PR, Dalli J, Abdulnour RE, Colas R, Ramon S, Phipps RP, Petasis NA, Kuchroo VK, Serhan CN, Levy BDJournal of immunology (Baltimore, Md. : 1950)Cutting edge: maresin-1 engages regulatory T cells to limit type 2 innate lymphoid cell activation and promote resolution of lung inflammation. J Immunol. 2015 Feb 01; 194(3):863-7.J Immunol2014-12-24T00:00:002014Cutting edge: maresin-1 engages regulatory T cells to limit type 2 innate lymphoid cell activation and promote resolution of lung inflammation.Authorship 547005125738673Schaefer L, Paik JM, Rennke H, Levy BD, Loscalzo JThe New England journal of medicineClinical problem solving: Itching for a diagnosis. N Engl J Med. 2015 Mar 05; 372(10):964-8.N Engl J Med2015-03-05T00:00:002015Clinical problem solving: Itching for a diagnosis.Authorship 3854881Authorship 4229701Authorship 20486020Authorship 49698618Authorship 4861293Authorship 5385362Authorship 542812Authorship 5606751Authorship 2484991Authorship 552921Authorship 5702802Authorship 906552Authorship 3945649Authorship 2555635Authorship 3165811Authorship 4799551Authorship 5489831Authorship 259421Authorship 2869781Authorship 3671496Authorship 3815541Authorship 2945801Authorship 4303622Authorship 4724165Authorship 485482Authorship 4968624Authorship 5220664Authorship 5577874Authorship 2792325Authorship 3756362Authorship 4086271Authorship 79629711Authorship 7895087Authorship 8001244Authorship 80095310Authorship 80573511Authorship 7928265Authorship 799627425137396Awji EG, Chand H, Bruse S, Smith KR, Colby JK, Mebratu Y, Levy BD, Tesfaigzi YAmerican journal of respiratory cell and molecular biologyWood smoke enhances cigarette smoke-induced inflammation by inducing the aryl hydrocarbon receptor repressor in airway epithelial cells. Am J Respir Cell Mol Biol. 2015 Mar; 52(3):377-86.Am J Respir Cell Mol Biol2015-03-01T00:00:002015Wood smoke enhances cigarette smoke-induced inflammation by inducing the aryl hydrocarbon receptor repressor in airway epithelial cells.23880288Bozinovski S, Anthony D, Anderson GP, Irving LB, Levy BD, Vlahos RPharmacology & therapeuticsTreating neutrophilic inflammation in COPD by targeting ALX/FPR2 resolution pathways. Pharmacol Ther. 2013 Dec; 140(3):280-9.Pharmacol Ther2013-07-21T00:00:002013Treating neutrophilic inflammation in COPD by targeting ALX/FPR2 resolution pathways.24846388Anthony D, McQualter JL, Bishara M, Lim EX, Yatmaz S, Seow HJ, Hansen M, Thompson M, Hamilton JA, Irving LB, Levy BD, Vlahos R, Anderson GP, Bozinovski SFASEB journal : official publication of the Federation of American Societies for Experimental BiologySAA drives proinflammatory heterotypic macrophage differentiation in the lung via CSF-1R-dependent signaling. FASEB J. 2014 Sep; 28(9):3867-77.FASEB J2014-05-20T00:00:002014SAA drives proinflammatory heterotypic macrophage differentiation in the lung via CSF-1R-dependent signaling.25590812Thannickal VJ, Murthy M, Balch WE, Chandel NS, Meiners S, Eickelberg O, Selman M, Pardo A, White ES, Levy BD, Busse PJ, Tuder RM, Antony VB, Sznajder JI, Budinger GRAmerican journal of respiratory and critical care medicineBlue journal conference. Aging and susceptibility to lung disease. Am J Respir Crit Care Med. 2015 Feb 01; 191(3):261-9.Am J Respir Crit Care Med2015-02-01T00:00:002015Blue journal conference. Aging and susceptibility to lung disease.Authorship 647243Authorship 286573Authorship 3268651Authorship 388312Authorship 4973804Authorship 584102Authorship 808231426132944Geller BJ, Stone RM, Merola JF, Levy BD, Loscalzo JThe New England journal of medicineCLINICAL PROBLEM-SOLVING. A Man with Fever, Cough, and Rash. N Engl J Med. 2015 Jul 02; 373(1):74-80.N Engl J Med2015-07-02T00:00:002015CLINICAL PROBLEM-SOLVING. A Man with Fever, Cough, and Rash.Authorship 8167566Authorship 8179302226116507Fang X, Abbott J, Cheng L, Colby JK, Lee JW, Levy BD, Matthay MAJournal of immunology (Baltimore, Md. : 1950)Human Mesenchymal Stem (Stromal) Cells Promote the Resolution of Acute Lung Injury in Part through Lipoxin A4. J Immunol. 2015 Aug 01; 195(3):875-81.J Immunol2015-06-26T00:00:002015Human Mesenchymal Stem (Stromal) Cells Promote the Resolution of Acute Lung Injury in Part through Lipoxin A4.26119026Talbot S, Abdulnour RE, Burkett PR, Lee S, Cronin SJ, Pascal MA, Laedermann C, Foster SL, Tran JV, Lai N, Chiu IM, Ghasemlou N, DiBiase M, Roberson D, Von Hehn C, Agac B, Haworth O, Seki H, Penninger JM, Kuchroo VK, Bean BP, Levy BD, Woolf CJNeuronSilencing Nociceptor Neurons Reduces Allergic Airway Inflammation. Neuron. 2015 Jul 15; 87(2):341-54.Neuron2015-06-25T00:00:002015Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation.Authorship 3648871Authorship 820409225726564Barnig C, Levy BDEuropean respiratory review : an official journal of the European Respiratory SocietyInnate immunity is a key factor for the resolution of inflammation in asthma. Eur Respir Rev. 2015 Mar; 24(135):141-53.Eur Respir Rev2015-03-01T00:00:002015Innate immunity is a key factor for the resolution of inflammation in asthma.Authorship 5057832Authorship 5225965Authorship 5396181Authorship 4446684Authorship 4616713Authorship 4775462Authorship 851102126305520Levy BD, Noel PJ, Freemer MM, Cloutier MM, Georas SN, Jarjour NN, Ober C, Woodruff PG, Barnes KC, Bender BG, Camargo CA, Chupp GL, Denlinger LC, Fahy JV, Fitzpatrick AM, Fuhlbrigge A, Gaston BM, Hartert TV, Kolls JK, Lynch SV, Moore WC, Morgan WJ, Nadeau KC, Ownby DR, Solway J, Szefler SJ, Wenzel SE, Wright RJ, Smith RA, Erzurum SCAmerican journal of respiratory and critical care medicineFuture Research Directions in Asthma. An NHLBI Working Group Report. Am J Respir Crit Care Med. 2015 Dec 01; 192(11):1366-72.Am J Respir Crit Care Med2015-12-01T00:00:002015Future Research Directions in Asthma. An NHLBI Working Group Report.Authorship 8524021526543094Liu CL, Wang Y, Liao M, Wemmelund H, Ren J, Fernandes C, Zhou Y, Sukhova GK, Lindholt JS, Johnsen SP, Zhang JY, Cheng X, Huang X, Daugherty A, Levy BD, Libby P, Shi GPArteriosclerosis, thrombosis, and vascular biologyAllergic Lung Inflammation Aggravates Angiotensin II-Induced Abdominal Aortic Aneurysms in Mice. Arterioscler Thromb Vasc Biol. 2016 Jan; 36(1):69-77.Arterioscler Thromb Vasc Biol2015-11-05T00:00:002015Allergic Lung Inflammation Aggravates Angiotensin II-Induced Abdominal Aortic Aneurysms in Mice.Authorship 8556002Authorship 855571426039320Colby JK, Gott KM, Wilder JA, Levy BDAmerican journal of respiratory cell and molecular biologyLipoxin Signaling in Murine Lung Host Responses to Cryptococcus neoformans Infection. Am J Respir Cell Mol Biol. 2016 Jan; 54(1):25-33.Am J Respir Cell Mol Biol2016-01-01T00:00:002016Lipoxin Signaling in Murine Lung Host Responses to Cryptococcus neoformans Infection.26688348Basil MC, Levy BDNature reviews. ImmunologySpecialized pro-resolving mediators: endogenous regulators of infection and inflammation. Nat Rev Immunol. 2016 Jan; 16(1):51-67.Nat Rev Immunol2015-12-21T00:00:002015Specialized pro-resolving mediators: endogenous regulators of infection and inflammation.Authorship 4634973Authorship 845482Authorship 8658607Authorship 8692961526868210Liu CL, Wemmelund H, Wang Y, Liao M, Lindholt JS, Johnsen SP, Vestergaard H, Fernandes C, Sukhova GK, Cheng X, Zhang JY, Yang C, Huang X, Daugherty A, Levy BD, Libby P, Shi GPArteriosclerosis, thrombosis, and vascular biologyAsthma Associates With Human Abdominal Aortic Aneurysm and Rupture. Arterioscler Thromb Vasc Biol. 2016 Mar; 36(3):570-8.Arterioscler Thromb Vasc Biol2016-02-11T00:00:002016Asthma Associates With Human Abdominal Aortic Aneurysm and Rupture.26767950Hou HW, Wu L, Amador-Munoz DP, Vera MP, Coronata A, Englert JA, Levy BD, Baron RM, Han JLab on a chipBroad spectrum immunomodulation using biomimetic blood cell margination for sepsis therapy. Lab Chip. 2016 Feb 21; 16(4):688-99.Lab Chip2016-01-15T00:00:002016Broad spectrum immunomodulation using biomimetic blood cell margination for sepsis therapy.Authorship 388235326898714Liu CL, Wang Y, Liao M, Santos MM, Fernandes C, Sukhova GK, Zhang JY, Cheng X, Yang C, Huang X, Levy B, Libby P, Wu G, Shi GPTranslational research : the journal of laboratory and clinical medicineAllergic lung inflammation promotes atherosclerosis in apolipoprotein E-deficient mice. Transl Res. 2016 May; 171:1-16.Transl Res2016-02-01T00:00:002016Allergic lung inflammation promotes atherosclerosis in apolipoprotein E-deficient mice.27171898Colby JK, Abdulnour RE, Sham HP, Dalli J, Colas RA, Winkler JW, Hellmann J, Wong B, Cui Y, El-Chemaly S, Petasis NA, Spite M, Serhan CN, Levy BDThe American journal of pathologyResolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia. Am J Pathol. 2016 07; 186(7):1801-1813.Am J Pathol2016-05-10T00:00:002016Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia.Authorship 881804227158460Baron RM, Levy BDF1000ResearchRecent advances in understanding and treating ARDS. F1000Res. 2016; 5.F1000Res2016-04-22T00:00:002016Recent advances in understanding and treating ARDS.Authorship 5395111Authorship 56111420Authorship 889440142Assistant Professor1Associate Professor0Full Professor4Instructor5Other FacultyAuthorship 892009527283230Peters MC, McGrath KW, Hawkins GA, Hastie AT, Levy BD, Israel E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, Holguin F, Wenzel SE, Woodruff PG, Bleecker ER, Fahy JVThe Lancet. Respiratory medicinePlasma interleukin-6 concentrations, metabolic dysfunction, and asthma severity: a cross-sectional analysis of two cohorts. Lancet Respir Med. 2016 07; 4(7):574-584.Lancet Respir Med2016-06-06T00:00:002016Plasma interleukin-6 concentrations, metabolic dysfunction, and asthma severity: a cross-sectional analysis of two cohorts.Authorship 670633Authorship 896092226546247Duvall MG, Levy BDEuropean journal of pharmacologyDHA- and EPA-derived resolvins, protectins, and maresins in airway inflammation. Eur J Pharmacol. 2016 Aug 15; 785:144-155.Eur J Pharmacol2015-11-03T00:00:002015DHA- and EPA-derived resolvins, protectins, and maresins in airway inflammation.Authorship 5167684Authorship 900782327518666Aday AW, Saavedra AP, Levy BD, Loscalzo JThe New England journal of medicineCLINICAL PROBLEM-SOLVING. Prevention as Precipitant. N Engl J Med. 2016 Aug 04; 375(5):471-5.N Engl J Med2016-08-04T00:00:002016CLINICAL PROBLEM-SOLVING. Prevention as Precipitant.Authorship 90962410Authorship 909965427579639Lampson BL, Gray SW, Cibas ES, Levy BD, Loscalzo JThe New England journal of medicineCLINICAL PROBLEM-SOLVING. Tip of the Tongue. N Engl J Med. 2016 Sep 01; 375(9):880-6.N Engl J Med2016-09-01T00:00:002016CLINICAL PROBLEM-SOLVING. Tip of the Tongue.27044027Zambalde ÉP, Teixeira MM, Favarin DC, de Oliveira JR, Magalhães ML, Cunha MM, Silva WC, Okuma CH, Rodrigues V, Levy BD, Rogerio APInternational immunopharmacologyThe anti-inflammatory and pro-resolution effects of aspirin-triggered RvD1 (AT-RvD1) on peripheral blood mononuclear cells from patients with severe asthma. Int Immunopharmacol. 2016 Jun; 35:142-148.Int Immunopharmacol2016-04-16T00:00:002016The anti-inflammatory and pro-resolution effects of aspirin-triggered RvD1 (AT-RvD1) on peripheral blood mononuclear cells from patients with severe asthma.2020-03-31HARROD, KEVIN S2014-04-01Targeting MMP9 to Improve Outcomes in Serious Influenza InfectionsR01AI1114752014-05-31ISRAEL, ELLIOT2011-06-01Lipoxins in Severe Asthma (LIPSA)P50HL1071662014-05-31LEVY, BRUCE D2001-12-10Counter-Regulatory Lipid Mediators in Lung DiseaseR01HL0686692021-05-31LEVY, BRUCE D2015-06-23Monitoring peripheral blood leukocyte and immune responses in health and diseaseU24AI1186562011-05-31LEVY, BRUCE D2007-09-01Oxidative Stress and Anti-Inflammatory Lipids in Airway DiseaseR01HL0909272003-02-28LEVY, BRUCE D1998-03-10NOVEL LUNG DERIVED CHALONES--BIOSYNTHESIS AND BIOACTIONSK08HL0037882025-05-31LEVY, BRUCE D2014-05-20Specialized Pro-Resolving Mediators in AsthmaR01HL1225312026-06-30LEVY, BRUCE D1985-07-01Integrated Training in Respiratory ResearchT32HL0076332010-02-28LEVY, BRUCE D2005-06-15Lipid Mediators in the Resolution of Asthma ExacerbationsR01AI0680842011-06-30LEVY, BRUCE D2005-06-15Lipid Mediators In The Resolution of Asthma ExacerbationsR56AI0680842019-05-31ISRAEL, ELLIOT2011-08-09AMSA: ALXR/FBR Mediated Signaling in Severe AsthmaU10HL1091722021-03-31SERHAN, CHARLES NICHOLAS2011-04-01Resolution Mechanisms in Acute Inflammation: Resolution PharmacologyP01GM095467Principal InvestigatorPrincipal InvestigatorPrincipal InvestigatorCo-Principal InvestigatorCo-Principal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorCo-Principal InvestigatorPrincipal InvestigatorPrincipal InvestigatorAuthorship 912790626075216de Oliveira JR, Favarin DC, Tanaka SC, Balarin MA, Teixeira DN, Levy BD, Rogério Ade PBioMed research internationalAT-RvD1 modulates CCL-2 and CXCL-8 production and NF-?B, STAT-6, SOCS1, and SOCS3 expression on bronchial epithelial cells stimulated with IL-4. Biomed Res Int. 2015; 2015:178369.Biomed Res Int2015-05-05T00:00:002015AT-RvD1 modulates CCL-2 and CXCL-8 production and NF-?B, STAT-6, SOCS1, and SOCS3 expression on bronchial epithelial cells stimulated with IL-4.Authorship 88550127816447Klein JP, Stover DG, Oxnard GR, Levy BD, Loscalzo JThe American journal of medicineRestoring Balance: Paraneoplastic Cerebellar Degeneration. Am J Med. 2017 Mar; 130(3):e85-e87.Am J Med2016-11-02T00:00:002016Restoring Balance: Paraneoplastic Cerebellar Degeneration.Authorship 4235896Authorship 8368020Authorship 1942951Authorship 2401993Authorship 2867763Authorship 940245627632672Dalli J, Colas RA, Quintana C, Barragan-Bradford D, Hurwitz S, Levy BD, Choi AM, Serhan CN, Baron RMCritical care medicineHuman Sepsis Eicosanoid and Proresolving Lipid Mediator Temporal Profiles: Correlations With Survival and Clinical Outcomes. Crit Care Med. 2017 Jan; 45(1):58-68.Crit Care Med2017-01-01T00:00:002017Human Sepsis Eicosanoid and Proresolving Lipid Mediator Temporal Profiles: Correlations With Survival and Clinical Outcomes.Authorship 9433892727556234Denlinger LC, Phillips BR, Ramratnam S, Ross K, Bhakta NR, Cardet JC, Castro M, Peters SP, Phipatanakul W, Aujla S, Bacharier LB, Bleecker ER, Comhair SA, Coverstone A, DeBoer M, Erzurum SC, Fain SB, Fajt M, Fitzpatrick AM, Gaffin J, Gaston B, Hastie AT, Hawkins GA, Holguin F, Irani AM, Israel E, Levy BD, Ly N, Meyers DA, Moore WC, Myers R, Opina MT, Peters MC, Schiebler ML, Sorkness RL, Teague WG, Wenzel SE, Woodruff PG, Mauger DT, Fahy JV, Jarjour NNAmerican journal of respiratory and critical care medicineInflammatory and Comorbid Features of Patients with Severe Asthma and Frequent Exacerbations. Am J Respir Crit Care Med. 2017 02 01; 195(3):302-313.Am J Respir Crit Care Med2017-02-01T00:00:002017Inflammatory and Comorbid Features of Patients with Severe Asthma and Frequent Exacerbations.Authorship 945807328029929Ramaswami R, Serhan CN, Levy BD, Makrides MThe New England journal of medicineFish Oil Supplementation in Pregnancy. N Engl J Med. 2016 12 29; 375(26):2599-2601.N Engl J Med2016-12-29T00:00:002016Fish Oil Supplementation in Pregnancy.Authorship 946523927472835Mathews JA, Krishnamoorthy N, Kasahara DI, Cho Y, Wurmbrand AP, Ribeiro L, Smith D, Umetsu D, Levy BD, Shore SAEnvironmental health perspectivesIL-33 Drives Augmented Responses to Ozone in Obese Mice. Environ Health Perspect. 2017 02; 125(2):246-253.Environ Health Perspect2016-07-29T00:00:002016IL-33 Drives Augmented Responses to Ozone in Obese Mice.Authorship 949915427705260Massarotti EM, Sax PE, Compton L, Levy BD, Loscalzo JThe New England journal of medicineTesting Limits. N Engl J Med. 2016 Oct 06; 375(14):1383-1388.N Engl J Med2016-10-06T00:00:002016Testing Limits.Authorship 9551231927967215Phipatanakul W, Mauger DT, Sorkness RL, Gaffin JM, Holguin F, Woodruff PG, Ly NP, Bacharier LB, Bhakta NR, Moore WC, Bleecker ER, Hastie AT, Meyers DA, Castro M, Fahy JV, Fitzpatrick AM, Gaston BM, Jarjour NN, Levy BD, Peters SP, Teague WG, Fajt M, Wenzel SE, Erzurum SC, Israel EAmerican journal of respiratory and critical care medicineEffects of Age and Disease Severity on Systemic Corticosteroid Responses in Asthma. Am J Respir Crit Care Med. 2017 06 01; 195(11):1439-1448.Am J Respir Crit Care Med2017-06-01T00:00:002017Effects of Age and Disease Severity on Systemic Corticosteroid Responses in Asthma.Authorship 958692412738799Ejima K, Layne MD, Carvajal IM, Kritek PA, Baron RM, Chen YH, Vom Saal J, Levy BD, Yet SF, Perrella MAFASEB journal : official publication of the Federation of American Societies for Experimental BiologyCyclooxygenase-2-deficient mice are resistant to endotoxin-induced inflammation and death. FASEB J. 2003 Jul; 17(10):1325-7.FASEB J2003-05-08T00:00:002003Cyclooxygenase-2-deficient mice are resistant to endotoxin-induced inflammation and death.10224233Levy BD, Fokin VV, Clark JM, Wakelam MJ, Petasis NA, Serhan CNFASEB journal : official publication of the Federation of American Societies for Experimental BiologyPolyisoprenyl phosphate (PIPP) signaling regulates phospholipase D activity: a 'stop' signaling switch for aspirin-triggered lipoxin A4. FASEB J. 1999 May; 13(8):903-11.FASEB J1999-05-01T00:00:001999Polyisoprenyl phosphate (PIPP) signaling regulates phospholipase D activity: a 'stop' signaling switch for aspirin-triggered lipoxin A4.15326007Levy BD, Katz JT, Wolf MA, Sillman JS, Handin RI, Dzau VJAcademic medicine : journal of the Association of American Medical CollegesAn initiative in mentoring to promote residents' and faculty members' careers. Acad Med. 2004 Sep; 79(9):845-50.Acad Med2004-09-01T00:00:002004An initiative in mentoring to promote residents' and faculty members' careers.17291857Moore WC, Bleecker ER, Curran-Everett D, Erzurum SC, Ameredes BT, Bacharier L, Calhoun WJ, Castro M, Chung KF, Clark MP, Dweik RA, Fitzpatrick AM, Gaston B, Hew M, Hussain I, Jarjour NN, Israel E, Levy BD, Murphy JR, Peters SP, Teague WG, Meyers DA, Busse WW, Wenzel SEThe Journal of allergy and clinical immunologyCharacterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. J Allergy Clin Immunol. 2007 Feb; 119(2):405-13.J Allergy Clin Immunol2007-02-01T00:00:002007Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program.11429545Levy BD, Clish CB, Schmidt B, Gronert K, Serhan CNNature immunologyLipid mediator class switching during acute inflammation: signals in resolution. Nat Immunol. 2001 Jul; 2(7):612-9.Nat Immunol2001-07-01T00:00:002001Lipid mediator class switching during acute inflammation: signals in resolution.15814734Fukunaga K, Kohli P, Bonnans C, Fredenburgh LE, Levy BDJournal of immunology (Baltimore, Md. : 1950)Cyclooxygenase 2 plays a pivotal role in the resolution of acute lung injury. J Immunol. 2005 Apr 15; 174(8):5033-9.J Immunol2005-04-15T00:00:002005Cyclooxygenase 2 plays a pivotal role in the resolution of acute lung injury.16990613Bonnans C, Levy BDAmerican journal of respiratory cell and molecular biologyLipid mediators as agonists for the resolution of acute lung inflammation and injury. Am J Respir Cell Mol Biol. 2007 Feb; 36(2):201-5.Am J Respir Cell Mol Biol2006-09-21T00:00:002006Lipid mediators as agonists for the resolution of acute lung inflammation and injury.Authorship 9770521328408159O'Donnell-Luria AH, Lin AP, Merugumala SK, Rohr F, Waisbren SE, Lynch R, Tchekmedyian V, Goldberg AD, Bellinger A, McFaline-Figueroa JR, Simon T, Gershanik EF, Levy BD, Cohen DE, Samuels MA, Berry GT, Frank NYMolecular genetics and metabolismBrain MRS glutamine as a biomarker to guide therapy of hyperammonemic coma. Mol Genet Metab. 2017 05; 121(1):9-15.Mol Genet Metab2017-03-10T00:00:002017Brain MRS glutamine as a biomarker to guide therapy of hyperammonemic coma.11190418Kitch BT, Levy BD, Fanta CHDrugs & agingLate onset asthma: epidemiology, diagnosis and treatment. Drugs Aging. 2000 Nov; 17(5):385-97.Drugs Aging2000-11-01T00:00:002000Late onset asthma: epidemiology, diagnosis and treatment.16046112Levy BDProstaglandins, leukotrienes, and essential fatty acidsLipoxins and lipoxin analogs in asthma. Prostaglandins Leukot Essent Fatty Acids. 2005 Sep-Oct; 73(3-4):231-7.Prostaglandins Leukot Essent Fatty Acids2005-09-01T00:00:002005Lipoxins and lipoxin analogs in asthma.75 Francis StBrigham and Womens HospitalPulmonary and Critical Care75 Francis StBoston02115MA17182589Levy BD, Kohli P, Gotlinger K, Haworth O, Hong S, Kazani S, Israel E, Haley KJ, Serhan CNJournal of immunology (Baltimore, Md. : 1950)Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness. J Immunol. 2007 Jan 01; 178(1):496-502.J Immunol2007-01-01T00:00:002007Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness.9547611Levy BD, Drazen JM, Serhan CNAdvances in experimental medicine and biologyAgonist-induced lipoxin A4 generation in vitro and in aspirin-sensitive asthmatics: detection by a novel lipoxin A4-ELISA. Adv Exp Med Biol. 1997; 400B:611-5.Adv Exp Med Biol1997-01-01T00:00:001997Agonist-induced lipoxin A4 generation in vitro and in aspirin-sensitive asthmatics: detection by a novel lipoxin A4-ELISA.19146388Rappley I, Gitler AD, Selvy PE, LaVoie MJ, Levy BD, Brown HA, Lindquist S, Selkoe DJBiochemistryEvidence that alpha-synuclein does not inhibit phospholipase D. Biochemistry. 2009 Feb 10; 48(5):1077-83.Biochemistry2009-02-10T00:00:002009Evidence that alpha-synuclein does not inhibit phospholipase D.16565483Bonnans C, Fukunaga K, Levy MA, Levy BDThe American journal of pathologyLipoxin A(4) regulates bronchial epithelial cell responses to acid injury. Am J Pathol. 2006 Apr; 168(4):1064-72.Am J Pathol2006-04-01T00:00:002006Lipoxin A(4) regulates bronchial epithelial cell responses to acid injury.Authorship 984435328455109Duvall MG, Bruggemann TR, Levy BDMolecular aspects of medicineBronchoprotective mechanisms for specialized pro-resolving mediators in the resolution of lung inflammation. Mol Aspects Med. 2017 Dec; 58:44-56.Mol Aspects Med2017-05-17T00:00:002017Bronchoprotective mechanisms for specialized pro-resolving mediators in the resolution of lung inflammation.20869861Levy BD, Zhang QY, Bonnans C, Primo V, Reilly JJ, Perkins DL, Liang Y, Amin Arnaout M, Nikolic B, Serhan CNProstaglandins, leukotrienes, and essential fatty acidsThe endogenous pro-resolving mediators lipoxin A4 and resolvin E1 preserve organ function in allograft rejection. Prostaglandins Leukot Essent Fatty Acids. 2011 Jan-Feb; 84(1-2):43-50.Prostaglandins Leukot Essent Fatty Acids2010-09-24T00:00:002010The endogenous pro-resolving mediators lipoxin A4 and resolvin E1 preserve organ function in allograft rejection.21215925Boyce JA, Assa'a A, Burks AW, Jones SM, Sampson HA, Wood RA, Plaut M, Cooper SF, Fenton MJ, Arshad SH, Bahna SL, Beck LA, Byrd-Bredbenner C, Camargo CA, Eichenfield L, Furuta GT, Hanifin JM, Jones C, Kraft M, Levy BD, Lieberman P, Luccioli S, McCall KM, Schneider LC, Simon RA, Simons FE, Teach SJ, Yawn BP, Schwaninger JMNutrition (Burbank, Los Angeles County, Calif.)Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-Sponsored Expert Panel Report. Nutrition. 2011 Feb; 27(2):253-67.Nutrition2011-02-01T00:00:002011Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-Sponsored Expert Panel Report.12861081Serhan CN, Levy BProceedings of the National Academy of Sciences of the United States of AmericaSuccess of prostaglandin E2 in structure-function is a challenge for structure-based therapeutics. Proc Natl Acad Sci U S A. 2003 Jul 22; 100(15):8609-11.Proc Natl Acad Sci U S A2003-07-14T00:00:002003Success of prostaglandin E2 in structure-function is a challenge for structure-based therapeutics.9539066Levy BD, Kitch B, Fanta CHIntensive care medicineMedical and ventilatory management of status asthmaticus. Intensive Care Med. 1998 Feb; 24(2):105-17.Intensive Care Med1998-02-01T00:00:001998Medical and ventilatory management of status asthmaticus.14734770Gronert K, Kantarci A, Levy BD, Clish CB, Odparlik S, Hasturk H, Badwey JA, Colgan SP, Van Dyke TE, Serhan CNJournal of immunology (Baltimore, Md. : 1950)A molecular defect in intracellular lipid signaling in human neutrophils in localized aggressive periodontal tissue damage. J Immunol. 2004 Feb 01; 172(3):1856-61.J Immunol2004-02-01T00:00:002004A molecular defect in intracellular lipid signaling in human neutrophils in localized aggressive periodontal tissue damage.16041402Levy BD, Hickey L, Morris AJ, Larvie M, Keledjian R, Petasis NA, Bannenberg G, Serhan CNBritish journal of pharmacologyNovel polyisoprenyl phosphates block phospholipase D and human neutrophil activation in vitro and murine peritoneal inflammation in vivo. Br J Pharmacol. 2005 Oct; 146(3):344-51.Br J Pharmacol2005-10-01T00:00:002005Novel polyisoprenyl phosphates block phospholipase D and human neutrophil activation in vitro and murine peritoneal inflammation in vivo.8376607Levy BD, Romano M, Chapman HA, Reilly JJ, Drazen J, Serhan CNThe Journal of clinical investigationHuman alveolar macrophages have 15-lipoxygenase and generate 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid and lipoxins. J Clin Invest. 1993 Sep; 92(3):1572-9.J Clin Invest1993-09-01T00:00:001993Human alveolar macrophages have 15-lipoxygenase and generate 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid and lipoxins.16567384Bonnans C, Fukunaga K, Keledjian R, Petasis NA, Levy BDThe Journal of experimental medicineRegulation of phosphatidylinositol 3-kinase by polyisoprenyl phosphates in neutrophil-mediated tissue injury. J Exp Med. 2006 Apr 17; 203(4):857-63.J Exp Med2006-03-27T00:00:002006Regulation of phosphatidylinositol 3-kinase by polyisoprenyl phosphates in neutrophil-mediated tissue injury.16940203Levy BDCirculationMyocardial 15-epi-lipoxin A4 generation provides a new mechanism for the immunomodulatory effects of statins and thiazolidinediones. Circulation. 2006 Aug 29; 114(9):873-5.Circulation2006-08-29T00:00:002006Myocardial 15-epi-lipoxin A4 generation provides a new mechanism for the immunomodulatory effects of statins and thiazolidinediones.20623098Carlo T, Levy BDTheScientificWorldJournalMolecular circuits of resolution in airway inflammation. ScientificWorldJournal. 2010 Jul 07; 10:1386-99.ScientificWorldJournal2010-07-07T00:00:002010Molecular circuits of resolution in airway inflammation.16373400Hasturk H, Kantarci A, Ohira T, Arita M, Ebrahimi N, Chiang N, Petasis NA, Levy BD, Serhan CN, Van Dyke TEFASEB journal : official publication of the Federation of American Societies for Experimental BiologyRvE1 protects from local inflammation and osteoclast- mediated bone destruction in periodontitis. FASEB J. 2006 Feb; 20(2):401-3.FASEB J2005-12-22T00:00:002005RvE1 protects from local inflammation and osteoclast- mediated bone destruction in periodontitis.16464866Fukunaga K, Arita M, Takahashi M, Morris AJ, Pfeffer M, Levy BDThe Journal of biological chemistryIdentification and functional characterization of a presqualene diphosphate phosphatase. J Biol Chem. 2006 Apr 07; 281(14):9490-7.J Biol Chem2006-02-07T00:00:002006Identification and functional characterization of a presqualene diphosphate phosphatase.22216845Gavin MC, Morse D, Partridge AH, Levy BD, Loscalzo JThe New England journal of medicineClinical problem-solving. Breathless. N Engl J Med. 2012 Jan 05; 366(1):75-81.N Engl J Med2012-01-05T00:00:002012Clinical problem-solving. Breathless.10973792Levy BD, Serhan CNBiochemical and biophysical research communicationsPolyisoprenyl phosphate signaling: topography in human neutrophils. Biochem Biophys Res Commun. 2000 Sep 07; 275(3):739-45.Biochem Biophys Res Commun2000-09-07T00:00:002000Polyisoprenyl phosphate signaling: topography in human neutrophils.19220020Carlo T, Petasis NA, Levy BDBiochemistryActivation of polyisoprenyl diphosphate phosphatase 1 remodels cellular presqualene diphosphate. Biochemistry. 2009 Apr 07; 48(13):2997-3004.Biochemistry2009-04-07T00:00:002009Activation of polyisoprenyl diphosphate phosphatase 1 remodels cellular presqualene diphosphate.22929102Levy BD, Vachier I, Serhan CNClinics in chest medicineResolution of inflammation in asthma. Clin Chest Med. 2012 Sep; 33(3):559-70.Clin Chest Med2012-07-25T00:00:002012Resolution of inflammation in asthma.Authorship 100084024Authorship 10065832228724795Ricklefs I, Barkas I, Duvall MG, Cernadas M, Grossman NL, Israel E, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Denlinger LC, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Levy BDJCI insightALX receptor ligands define a biochemical endotype for severe asthma. JCI Insight. 2017 Jul 20; 2(14).JCI Insight2017-07-20T00:00:002017ALX receptor ligands define a biochemical endotype for severe asthma.28783702Duvall MG, Barnig C, Cernadas M, Ricklefs I, Krishnamoorthy N, Grossman NL, Bhakta NR, Fahy JV, Bleecker ER, Castro M, Erzurum SC, Gaston BM, Jarjour NN, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Israel E, Levy BDScience immunologyNatural killer cell-mediated inflammation resolution is disabled in severe asthma. Sci Immunol. 2017 Mar 10; 2(9).Sci Immunol2017-03-10T00:00:002017Natural killer cell-mediated inflammation resolution is disabled in severe asthma.28767340Divakaran S, Dellaripa P, Kobzik L, Levy B, Loscalzo JThe New England journal of medicineAll That Wheezes…. N Engl J Med. 2017 08 03; 377(5):477-484.N Engl J Med2017-08-03T00:00:002017All That Wheezes….21134576Boyce JA, Assa'ad A, Burks AW, Jones SM, Sampson HA, Wood RA, Plaut M, Cooper SF, Fenton MJ, Arshad SH, Bahna SL, Beck LA, Byrd-Bredbenner C, Camargo CA, Eichenfield L, Furuta GT, Hanifin JM, Jones C, Kraft M, Levy BD, Lieberman P, Luccioli S, McCall KM, Schneider LC, Simon RA, Simons FE, Teach SJ, Yawn BP, Schwaninger JMThe Journal of allergy and clinical immunologyGuidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel. J Allergy Clin Immunol. 2010 Dec; 126(6 Suppl):S1-58.J Allergy Clin Immunol2010-12-01T00:00:002010Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel.Co-Principal Investigator21616147Bilal S, Haworth O, Wu L, Weylandt KH, Levy BD, Kang JXBiochimica et biophysica actaFat-1 transgenic mice with elevated omega-3 fatty acids are protected from allergic airway responses. Biochim Biophys Acta. 2011 Sep; 1812(9):1164-9.Biochim Biophys Acta2011-05-17T00:00:002011Fat-1 transgenic mice with elevated omega-3 fatty acids are protected from allergic airway responses.28866107Teague WG, Phillips BR, Fahy JV, Wenzel SE, Fitzpatrick AM, Moore WC, Hastie AT, Bleecker ER, Meyers DA, Peters SP, Castro M, Coverstone AM, Bacharier LB, Ly NP, Peters MC, Denlinger LC, Ramratnam S, Sorkness RL, Gaston BM, Erzurum SC, Comhair SAA, Myers RE, Zein J, DeBoer MD, Irani AM, Israel E, Levy B, Cardet JC, Phipatanakul W, Gaffin JM, Holguin F, Fajt ML, Aujla SJ, Mauger DT, Jarjour NNThe journal of allergy and clinical immunology. In practiceBaseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age. J Allergy Clin Immunol Pract. 2018 Mar - Apr; 6(2):545-554.e4.J Allergy Clin Immunol Pract2017-08-31T00:00:002017Baseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age.10933083Sanak M, Levy BD, Clish CB, Chiang N, Gronert K, Mastalerz L, Serhan CN, Szczeklik AThe European respiratory journalAspirin-tolerant asthmatics generate more lipoxins than aspirin-intolerant asthmatics. Eur Respir J. 2000 Jul; 16(1):44-9.Eur Respir J2000-07-01T00:00:002000Aspirin-tolerant asthmatics generate more lipoxins than aspirin-intolerant asthmatics.Authorship 10111762028902842Wallrapp A, Riesenfeld SJ, Burkett PR, Abdulnour RE, Nyman J, Dionne D, Hofree M, Cuoco MS, Rodman C, Farouq D, Haas BJ, Tickle TL, Trombetta JJ, Baral P, Klose CSN, Mahlakõiv T, Artis D, Rozenblatt-Rosen O, Chiu IM, Levy BD, Kowalczyk MS, Regev A, Kuchroo VKNatureThe neuropeptide NMU amplifies ILC2-driven allergic lung inflammation. Nature. 2017 09 21; 549(7672):351-356.Nature2017-09-13T00:00:002017The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation.20445184Britton KA, Stevenson WG, Levy BD, Katz JT, Loscalzo JThe New England journal of medicineClinical problem-solving. The beat goes on. N Engl J Med. 2010 May 06; 362(18):1721-6.N Engl J Med2010-05-06T00:00:002010Clinical problem-solving. The beat goes on.21134568Boyce JA, Assa'ad A, Burks AW, Jones SM, Sampson HA, Wood RA, Plaut M, Cooper SF, Fenton MJ, Arshad SH, Bahna SL, Beck LA, Byrd-Bredbenner C, Camargo CA, Eichenfield L, Furuta GT, Hanifin JM, Jones C, Kraft M, Levy BD, Lieberman P, Luccioli S, McCall KM, Schneider LC, Simon RA, Simons FE, Teach SJ, Yawn BP, Schwaninger JMThe Journal of allergy and clinical immunologyGuidelines for the Diagnosis and Management of Food Allergy in the United States: Summary of the NIAID-Sponsored Expert Panel Report. J Allergy Clin Immunol. 2010 12; 126(6):1105-18.J Allergy Clin Immunol2010-12-01T00:00:002010Guidelines for the Diagnosis and Management of Food Allergy in the United States: Summary of the NIAID-Sponsored Expert Panel Report.Authorship 10141801228957638Mathews JA, Krishnamoorthy N, Kasahara DI, Hutchinson J, Cho Y, Brand JD, Williams AS, Wurmbrand AP, Ribeiro L, Cuttitta F, Sunday ME, Levy BD, Shore SAAmerican journal of respiratory cell and molecular biologyAugmented Responses to Ozone in Obese Mice Require IL-17A and Gastrin-Releasing Peptide. Am J Respir Cell Mol Biol. 2018 03; 58(3):341-351.Am J Respir Cell Mol Biol2018-03-01T00:00:002018Augmented Responses to Ozone in Obese Mice Require IL-17A and Gastrin-Releasing Peptide.22762321Merola JF, Ghoroghchian PP, Samuels MA, Levy BD, Loscalzo JThe New England journal of medicineClinical problem-solving. At a loss. N Engl J Med. 2012 Jul 05; 367(1):67-72.N Engl J Med2012-07-05T00:00:002012Clinical problem-solving. At a loss.22968127Katz JN, Chaisson CE, Cole B, Guermazi A, Hunter DJ, Jones M, Levy BA, Mandl LA, Martin S, Marx RG, Safran-Norton C, Roemer FW, Skoniecki D, Solomon DH, Spindler KP, Wright J, Wright RW, Losina EContemporary clinical trialsThe MeTeOR trial (Meniscal Tear in Osteoarthritis Research): rationale and design features. Contemp Clin Trials. 2012 Nov; 33(6):1189-96.Contemp Clin Trials2012-09-05T00:00:002012The MeTeOR trial (Meniscal Tear in Osteoarthritis Research): rationale and design features.10943332Serhan CN, Levy BD, Clish CB, Gronert K, Chiang NErnst Schering Research Foundation workshopLipoxins, aspirin-triggered 15-epi-lipoxin stable analogs and their receptors in anti-inflammation: a window for therapeutic opportunity. Ernst Schering Res Found Workshop. 2000; (31):143-85.Ernst Schering Res Found Workshop2000-01-01T00:00:002000Lipoxins, aspirin-triggered 15-epi-lipoxin stable analogs and their receptors in anti-inflammation: a window for therapeutic opportunity.16320317Levy BDArthritis and rheumatismEicosanoids in scleroderma: lung disease hangs in the balance. Arthritis Rheum. 2005 Dec; 52(12):3693-7.Arthritis Rheum2005-12-01T00:00:002005Eicosanoids in scleroderma: lung disease hangs in the balance.17416409Chanez P, Wenzel SE, Anderson GP, Anto JM, Bel EH, Boulet LP, Brightling CE, Busse WW, Castro M, Dahlen B, Dahlen SE, Fabbri LM, Holgate ST, Humbert M, Gaga M, Joos GF, Levy B, Rabe KF, Sterk PJ, Wilson SJ, Vachier IThe Journal of allergy and clinical immunologySevere asthma in adults: what are the important questions? J Allergy Clin Immunol. 2007 Jun; 119(6):1337-48.J Allergy Clin Immunol2007-04-09T00:00:002007Severe asthma in adults: what are the important questions?19890132Cuker A, Connors JM, Katz JT, Levy BD, Loscalzo JThe New England journal of medicineClinical problem-solving. A bloody mystery. N Engl J Med. 2009 Nov 05; 361(19):1887-94.N Engl J Med2009-11-05T00:00:002009Clinical problem-solving. A bloody mystery.20007539Seki H, Fukunaga K, Arita M, Arai H, Nakanishi H, Taguchi R, Miyasho T, Takamiya R, Asano K, Ishizaka A, Takeda J, Levy BDJournal of immunology (Baltimore, Md. : 1950)The anti-inflammatory and proresolving mediator resolvin E1 protects mice from bacterial pneumonia and acute lung injury. J Immunol. 2010 Jan 15; 184(2):836-43.J Immunol2009-12-09T00:00:002009The anti-inflammatory and proresolving mediator resolvin E1 protects mice from bacterial pneumonia and acute lung injury.20925549Miller AL, Falk RH, Levy BD, Loscalzo JThe New England journal of medicineClinical problem-solving. A heavy heart. N Engl J Med. 2010 Oct 07; 363(15):1464-9.N Engl J Med2010-10-07T00:00:002010Clinical problem-solving. A heavy heart.21310308Boyce JA, Assa'ad A, Burks AW, Jones SM, Sampson HA, Wood RA, Plaut M, Cooper SF, Fenton MJ, Arshad SH, Bahna SL, Beck LA, Byrd-Bredbenner C, Camargo CA, Eichenfield L, Furuta GT, Hanifin JM, Jones C, Kraft M, Levy BD, Lieberman P, Luccioli S, McCall KM, Schneider LC, Simon RA, Simons FE, Teach SJ, Yawn BP, Schwaninger JMNutrition research (New York, N.Y.)Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-sponsored expert panel report. Nutr Res. 2011 Jan; 31(1):61-75.Nutr Res2011-01-01T00:00:002011Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-sponsored expert panel report.23447017Barnig C, Cernadas M, Dutile S, Liu X, Perrella MA, Kazani S, Wechsler ME, Israel E, Levy BDScience translational medicineLipoxin A4 regulates natural killer cell and type 2 innate lymphoid cell activation in asthma. Sci Transl Med. 2013 Feb 27; 5(174):174ra26.Sci Transl Med2013-02-27T00:00:002013Lipoxin A4 regulates natural killer cell and type 2 innate lymphoid cell activation in asthma.17431098Parameswaran K, Radford K, Fanat A, Stephen J, Bonnans C, Levy BD, Janssen LJ, Cox PGAmerican journal of respiratory cell and molecular biologyModulation of human airway smooth muscle migration by lipid mediators and Th-2 cytokines. Am J Respir Cell Mol Biol. 2007 Aug; 37(2):240-7.Am J Respir Cell Mol Biol2007-04-12T00:00:002007Modulation of human airway smooth muscle migration by lipid mediators and Th-2 cytokines.15175433Levy BD, O'Connell JJThe New England journal of medicineHealth care for homeless persons. N Engl J Med. 2004 Jun 03; 350(23):2329-32.N Engl J Med2004-06-03T00:00:002004Health care for homeless persons.15961693Levy BD, Bonnans C, Silverman ES, Palmer LJ, Marigowda G, Israel EAmerican journal of respiratory and critical care medicineDiminished lipoxin biosynthesis in severe asthma. Am J Respir Crit Care Med. 2005 Oct 01; 172(7):824-30.Am J Respir Crit Care Med2005-06-16T00:00:002005Diminished lipoxin biosynthesis in severe asthma.16520503Furin J, Farmer P, Wolf M, Levy B, Judd A, Paternek M, Hurtado R, Katz JJournal of health care for the poor and underservedA novel training model to address health problems in poor and underserved populations. 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