Harvard Catalyst Profiles

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Robert Stephen Brown, M.D.

Title
Institution
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Biography
education and training
Harvard College, Cambridge, MAAB06/1959Biochemical Science
Columbia College of Physicians and Surgeons, New York, NYMD06/1963Medicine
awards and honors
2020
Dean’s Community Service Faculty Award
2016
Honor for Outstanding Contributions in Nephrology Education
2008
Parker J. Palmer “Courage to Teach” Award
2002 - 2022
Who’s Who in America
2000
Daniel D. Federman Outstanding Clinical Educator Award
1996
Outstanding Physician, Gift of Life Award
1994 - 2019
Best Doctors in America
1962
Alpha Omega Alpha Honor Medical Society

Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. (Aditya Pawar) Jan 1, 2022
    The International Society of Nephrology and the Transplantation Society (ISN-TTS)
    Sister Transplant Centers Pair Program Grant
    Role Description: The ISN-TTS Sister Transplant Centers Program nurtures a partnership between centers from low-resource countries, in this grant the Hôpital Universitaire de Mirebalais (HUM) in Haiti, and organizations from high income countries, in this grant BIDMC. The Program grant supplies a framework and list of benefits to help HUM develop a kidney transplant program in Haiti. The sister program seeks to utilize the experience of BIDMC to train surgeons and medical transplant physicians at HUM as part of a sustainable partnership between the two institutions. This ISN-TTS program grant recognizes and builds upon the efforts I have already performed to bring kidney care, dialysis and education to HUM in Haiti (see TORCH in Report of Technological and Other Scientific Innovations below
    Role: Co-Investigator
  2. VX19-FSG-001 (Robert S Brown, MD) Jan 1, 2020 - Jan 14, 2022
    Vertex Pharmaceuticals Inc.
    A Natural History Study of Patients with Biopsy proven Focal Segmental Glomerulosclerosis and Nephrotic Range Proteinuria who are of Recent African Ancestry or have 2 APOL1 Risk Alleles
    Role Description: This is a retrospective, natural history study of patients with kidney biopsy-proven focal segmental glomerulosclerosis (FSGS) and nephrotic range proteinuria who are either of recent African ancestry or have 2 APOL1 risk alleles. The study is designed to assess the proportion of patients who achieve spontaneous remission, an important consideration in the development of investigational drugs for this uncommon disease that will not be likely to have data from randomized controlled studies.
    Role: Site Principal Investigator
  3. DK076169 (Robert S. Brown) Jan 1, 2014 - Dec 31, 2016
    NIDDK Diabetic Complications Consortium (DiaComp)
    MR elastography for noninvasive assessment of fibrosis in diabetic kidney disease
    Role Description: This pilot study demonstrated that magnetic resonance imaging (MRI) with non-invasively measured MR elastography (MRE) shear stiffness and arterial spin labeling (ASL) kidney perfusion correlates with fibrosis as graded by kidney biopsy and standard kidney function tests (eGFR) in patients with Type 1 and Type 2 diabetes with diabetic nephropathy.
    Role: Principal Investigator
  4. UL1 RR 025758 (Robert S. Brown) Jan 1, 2012 - Dec 31, 2014
    Harvard Catalyst, NIH & Harvard University
    MR elastography for assessment of kidney fibrosis in chronic kidney disease (CKD)
    Role Description: The study applied a novel MRI technique known as MR elastography (MRE) to assess tissue elasticity in order to detect and quantify kidney fibrosis in patients with CKD. If proven effective, this technique could become a useful noninvasive tool for assessing early renal disease when GFR is still normal and evaluate the efficacy of emerging treatments to delay fibrosis and CKD progression.
    Role: Principal Investigator
  5. SCD-003 (David Hume, MD) Jan 1, 2012 - Dec 31, 2013
    CytoPherx, Inc.
    A multi-center, randomized, controlled, pivotal study to assess the safety and efficacy of a Selective Cytopheretic Device (SCD) in patients with acute kidney injury (AKI)
    Role Description: The goal of the study was whether the SCD treatment, by removing activated circulating leukocytes, when used together with continuous renal replacement therapy (CRRT), as compared to standard of care CRRT alone, would improve survival in patients with AKI due to septic shock and reduce the duration of maintenance dialysis secondary to acute tubular necrosis. That goal was not achieved.
    Role: Co-Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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© 2024 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.