YT6Yu-HuaTsengYu-Hua Tseng, Ph.D.42.33839600000000-71.1084030000000020440Tseng, Yu-Hua617/264-2753Professor of Medicinecatalyst:eCommonsLogineCommons Loginprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:address2address line 2vivo:address3address line 3vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsvivo:phoneNumberphonePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofvivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson9140083Tseng YH, Kessler MA, Schuler LAMolecular and cellular endocrinologyRegulation of interleukin (IL)-1alpha, IL-1beta, and IL-6 expression by growth hormone and prolactin in bovine thymic stromal cells. Mol Cell Endocrinol. 1997 Apr 04; 128(1-2):117-27.Mol Cell Endocrinol1997-04-04T00:00:001997Regulation of interleukin (IL)-1alpha, IL-1beta, and IL-6 expression by growth hormone and prolactin in bovine thymic stromal cells.15895078Tseng YH, Butte AJ, Kokkotou E, Yechoor VK, Taniguchi CM, Kriauciunas KM, Cypess AM, Niinobe M, Yoshikawa K, Patti ME, Kahn CRNature cell biologyPrediction of preadipocyte differentiation by gene expression reveals role of insulin receptor substrates and necdin. Nat Cell Biol. 2005 Jun; 7(6):601-11.Nat Cell Biol2005-05-15T00:00:002005Prediction of preadipocyte differentiation by gene expression reveals role of insulin receptor substrates and necdin.19896888Schulz TJ, Tseng YHCytokine & growth factor reviewsEmerging role of bone morphogenetic proteins in adipogenesis and energy metabolism. Cytokine Growth Factor Rev. 2009 Oct-Dec; 20(5-6):523-31.Cytokine Growth Factor Rev2009-11-06T00:00:002009Emerging role of bone morphogenetic proteins in adipogenesis and energy metabolism.14730378Cohen SE, Tseng YH, Michael MD, Kahn CRDiabetologiaEffects of insulin-sensitising agents in mice with hepatic insulin resistance. Diabetologia. 2004 Mar; 47(3):407-411.Diabetologia2004-01-17T00:00:002004Effects of insulin-sensitising agents in mice with hepatic insulin resistance.10611312Zhu J, Tseng YH, Kantor JD, Rhodes CJ, Zetter BR, Moyers JS, Kahn CRProceedings of the National Academy of Sciences of the United States of AmericaInteraction of the Ras-related protein associated with diabetes rad and the putative tumor metastasis suppressor NM23 provides a novel mechanism of GTPase regulation. Proc Natl Acad Sci U S A. 1999 Dec 21; 96(26):14911-8.Proc Natl Acad Sci U S A1999-12-21T00:00:001999Interaction of the Ras-related protein associated with diabetes rad and the putative tumor metastasis suppressor NM23 provides a novel mechanism of GTPase regulation.20514071Tseng YH, Cypess AM, Kahn CRNature reviews. Drug discoveryCellular bioenergetics as a target for obesity therapy. Nat Rev Drug Discov. 2010 Jun; 9(6):465-82.Nat Rev Drug Discov2010-06-01T00:00:002010Cellular bioenergetics as a target for obesity therapy.14966273Tseng YH, Kriauciunas KM, Kokkotou E, Kahn CRMolecular and cellular biologyDifferential roles of insulin receptor substrates in brown adipocyte differentiation. Mol Cell Biol. 2004 Mar; 24(5):1918-29.Mol Cell Biol2004-03-01T00:00:002004Differential roles of insulin receptor substrates in brown adipocyte differentiation.17956727Gesta S, Tseng YH, Kahn CRCellDevelopmental origin of fat: tracking obesity to its source. Cell. 2007 Oct 19; 131(2):242-56.Cell2007-10-19T00:00:002007Developmental origin of fat: tracking obesity to its source.18325388Karagiannides I, Torres D, Tseng YH, Bowe C, Carvalho E, Espinoza D, Pothoulakis C, Kokkotou EGastroenterologySubstance P as a novel anti-obesity target. Gastroenterology. 2008 Mar; 134(3):747-55.Gastroenterology2008-03-01T00:00:002008Substance P as a novel anti-obesity target.22331196Townsend KL, Suzuki R, Huang TL, Jing E, Schulz TJ, Lee K, Taniguchi CM, Espinoza DO, McDougall LE, Zhang H, He TC, Kokkotou E, Tseng YHFASEB journal : official publication of the Federation of American Societies for Experimental BiologyBone morphogenetic protein 7 (BMP7) reverses obesity and regulates appetite through a central mTOR pathway. FASEB J. 2012 May; 26(5):2187-96.FASEB J2012-02-13T00:00:002012Bone morphogenetic protein 7 (BMP7) reverses obesity and regulates appetite through a central mTOR pathway.20584981Zhang H, Schulz TJ, Espinoza DO, Huang TL, Emanuelli B, Kristiansen K, Tseng YHMolecular and cellular biologyCross talk between insulin and bone morphogenetic protein signaling systems in brown adipogenesis. Mol Cell Biol. 2010 Sep; 30(17):4224-33.Mol Cell Biol2010-06-28T00:00:002010Cross talk between insulin and bone morphogenetic protein signaling systems in brown adipogenesis.22938691Townsend KL, An D, Lynes MD, Huang TL, Zhang H, Goodyear LJ, Tseng YHAntioxidants & redox signalingIncreased mitochondrial activity in BMP7-treated brown adipocytes, due to increased CPT1- and CD36-mediated fatty acid uptake. Antioxid Redox Signal. 2013 Jul 20; 19(3):243-57.Antioxid Redox Signal2012-10-09T00:00:002012Increased mitochondrial activity in BMP7-treated brown adipocytes, due to increased CPT1- and CD36-mediated fatty acid uptake.20360006Boucher J, Tseng YH, Kahn CRThe Journal of biological chemistryInsulin and insulin-like growth factor-1 receptors act as ligand-specific amplitude modulators of a common pathway regulating gene transcription. J Biol Chem. 2010 May 28; 285(22):17235-45.J Biol Chem2010-04-01T00:00:002010Insulin and insulin-like growth factor-1 receptors act as ligand-specific amplitude modulators of a common pathway regulating gene transcription.22596050Macotela Y, Emanuelli B, Mori MA, Gesta S, Schulz TJ, Tseng YH, Kahn CRDiabetesIntrinsic differences in adipocyte precursor cells from different white fat depots. Diabetes. 2012 Jul; 61(7):1691-9.Diabetes2012-05-17T00:00:002012Intrinsic differences in adipocyte precursor cells from different white fat depots.23538494Ziogas DC, Gras-Miralles B, Mustafa S, Geiger BM, Najarian RM, Nagel JM, Flier SN, Popov Y, Tseng YH, Kokkotou EAmerican journal of physiology. Gastrointestinal and liver physiologyAnti-melanin-concentrating hormone treatment attenuates chronic experimental colitis and fibrosis. Am J Physiol Gastrointest Liver Physiol. 2013 May 15; 304(10):G876-84.Am J Physiol Gastrointest Liver Physiol2013-03-28T00:00:002013Anti-melanin-concentrating hormone treatment attenuates chronic experimental colitis and fibrosis.17553579Mouche S, Mkaddem SB, Wang W, Katic M, Tseng YH, Carnesecchi S, Steger K, Foti M, Meier CA, Muzzin P, Kahn CR, Ogier-Denis E, Szanto IBiochimica et biophysica actaReduced expression of the NADPH oxidase NOX4 is a hallmark of adipocyte differentiation. Biochim Biophys Acta. 2007 Jul; 1773(7):1015-27.Biochim Biophys Acta2007-03-19T00:00:002007Reduced expression of the NADPH oxidase NOX4 is a hallmark of adipocyte differentiation.D052005Chemicals & Drugs51960.938928Bone Morphogenetic Protein Receptors, Type ID002001Anatomy2347540.631272Adipose Tissue, BrownD052437Anatomy721390.902595Adipocytes, BrownD050156Physiology1953560.786806AdipogenesisD022722Physiology1554280.717362ThermogenesisCell BiologyMedicinePediatricsStem Cell and Regenerative BiologyGastroenterologyJoslinGeneticsEndocrinologyBeth Israel Deaconess Medical CenterBoston Children's HospitalDana-Farber Cancer InstituteHarvard Medical SchoolJoslin Diabetes Center1176selected publications4.436960.00304303413research areas2.553220.011627836coauthor of125.03611.156560similar toSK198ShingoKajimuraShingo Kajimura, Ph.D.42.33789600000000-71.1072493000000040157Kajimura, ShingoProfessor of MedicineAJW14AmyWagersAmy J Wagers, Ph.D.42.33839600000000-71.108403000000001943Wagers, AmyForst Family Professor of Stem Cell and Regenerative BiologyEDR1EvanRosenEvan David Rosen, M.D., Ph.D.42.34620670000000-71.0997834000000084973Rosen, EvanProfessor of MedicineEG9EmanuelaGussoniEmanuela Gussoni, Ph.D.42.33790000000000-71.1059000000000088750Gussoni, EmanuelaAssociate Professor of PediatricsCSM3ChristosMantzorosChristos Mantzoros, M.D.42.34022770000000-71.1058540000000061846Mantzoros, ChristosProfessor of MedicineOH1OsamaHamdyOsama Hamdy, M.B.,B.Ch., M.D.42.33839600000000-71.1084030000000014853Hamdy, OsamaAssociate Professor of MedicineMAL7MyraLipesMyra Ann Lipes, M.D.,C.M.42.33839600000000-71.1084030000000053177Lipes, MyraAssociate Professor of MedicineLDM2LyleMitznerLyle D. Mitzner, M.D.42.33839600000000-71.1084030000000067172Mitzner, LyleAssistant Professor of MedicineCRK3C.KahnC. Ronald Kahn, M.D.42.33839600000000-71.1084030000000084269Kahn, C.Mary K. Iacocca Professor of MedicineLJG1LaurieGoodyearLaurie Joy Goodyear, Ph.D.42.33839600000000-71.1084030000000025240Goodyear, LaurieProfessor of MedicineSB24SudhaBiddingerSudha Biddinger, M.D.,Ph.D.42.33839600000000-71.1084030000000030232Biddinger, SudhaAssociate Professor of PediatricsEGK2EfiKokkotouEfi G. Kokkotou, M.D., Ph.D., Sc.D.42.34022770000000-71.1058540000000071416Kokkotou, EfiAssociate Professor of MedicineBMS5BruceSpiegelmanBruce Michael Spiegelman, Ph.D.42.33789600000000-71.1072493000000015280Spiegelman, BruceStanley J. Korsmeyer Professor of Cell Biology and MedicineAuthorship 1400404true1Assistant Professor of MedicineAssistant Professor of Medicinetrue1Mary K. Iacocca Professor of MedicineMary K. Iacocca Professor of Medicinetrue1Professor of MedicineProfessor of Medicinetrue1Stanley J. Korsmeyer Professor of Cell Biology and MedicineStanley J. Korsmeyer Professor of Cell Biology and Medicinetrue1Associate Professor of MedicineAssociate Professor of Medicinetrue1Professor of MedicineProfessor of Medicinetrue1Professor of MedicineProfessor of Medicine2024-01-31SPITE, MATTHEW R;TSENG, YU-HUA2020-04-01Role of brown fat-derived specialized pro-resolving lipid mediators in inflammation and metabolismR01DK122808Principal InvestigatorAuthorship 2182301true1Professor of MedicineProfessor of Medicine2021-09-15TSENG, YU-HUA2020-09-16Small Animal High Resolution Metabolic Analysis SystemS10OD028568Principal Investigatortrue1Associate Professor of MedicineAssociate Professor of Medicinetrue1Professor of MedicineProfessor of MedicineAuthorship 1514383136526875Tseng YHNature reviews. EndocrinologyAdipose tissue in communication: within and without. Nat Rev Endocrinol. 2023 02; 19(2):70-71.Nat Rev Endocrinol2023-02-01T00:00:002023Adipose tissue in communication: within and without.Authorship 18023215true1Associate Professor of MedicineAssociate Professor of MedicineAuthorship 4793411true1Forst Family Professor of Stem Cell and Regenerative BiologyForst Family Professor of Stem Cell and Regenerative Biologytrue1Associate Professor of PediatricsAssociate Professor of Pediatricstrue1Associate Professor of PediatricsAssociate Professor of PediatricsAuthorship 4518141323603815Cypess AM, White AP, Vernochet C, Schulz TJ, Xue R, Sass CA, Huang TL, Roberts-Toler C, Weiner LS, Sze C, Chacko AT, Deschamps LN, Herder LM, Truchan N, Glasgow AL, Holman AR, Gavrila A, Hasselgren PO, Mori MA, Molla M, Tseng YHNature medicineAnatomical localization, gene expression profiling and functional characterization of adult human neck brown fat. Nat Med. 2013 May; 19(5):635-9.Nat Med2013-04-21T00:00:002013Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat.Authorship 68745121Authorship 6867537Authorship 6872189Authorship 693047724071505Cypess AM, Doyle AN, Sass CA, Huang TL, Mowschenson PM, Rosen HN, Tseng YH, Palmer EL, Kolodny GMJournal of nuclear medicine : official publication, Society of Nuclear MedicineQuantification of human and rodent brown adipose tissue function using 99mTc-methoxyisobutylisonitrile SPECT/CT and 18F-FDG PET/CT. J Nucl Med. 2013 Nov; 54(11):1896-901.J Nucl Med2013-09-26T00:00:002013Quantification of human and rodent brown adipose tissue function using 99mTc-methoxyisobutylisonitrile SPECT/CT and 18F-FDG PET/CT.Authorship 1908528Authorship 248252Authorship 1791735Authorship 3139573Authorship 71118810Authorship 7096818Authorship 713801824678452Castiglioni A, Hettmer S, Lynes MD, Rao TN, Tchessalova D, Sinha I, Lee BT, Tseng YH, Wagers AJStem cell reportsIsolation of progenitors that exhibit myogenic/osteogenic bipotency in vitro by fluorescence-activated cell sorting from human fetal muscle. Stem Cell Reports. 2014 Jan 14; 2(1):92-106.Stem Cell Reports2014-01-14T00:00:002014Isolation of progenitors that exhibit myogenic/osteogenic bipotency in vitro by fluorescence-activated cell sorting from human fetal muscle.24485453Lee JH, Bhang DH, Beede A, Huang TL, Stripp BR, Bloch KD, Wagers AJ, Tseng YH, Ryeom S, Kim CFCellLung stem cell differentiation in mice directed by endothelial cells via a BMP4-NFATc1-thrombospondin-1 axis. Cell. 2014 Jan 30; 156(3):440-55.Cell2014-01-30T00:00:002014Lung stem cell differentiation in mice directed by endothelial cells via a BMP4-NFATc1-thrombospondin-1 axis.Authorship 3304283Authorship 727286224389130Townsend KL, Tseng YHTrends in endocrinology and metabolism: TEMBrown fat fuel utilization and thermogenesis. Trends Endocrinol Metab. 2014 Apr; 25(4):168-77.Trends Endocrinol Metab2014-01-02T00:00:002014Brown fat fuel utilization and thermogenesis.Authorship 2219299Authorship 732213424898859Huang P, Schulz TJ, Beauvais A, Tseng YH, Gussoni ENature communicationsIntramuscular adipogenesis is inhibited by myo-endothelial progenitors with functioning Bmpr1a signalling. Nat Commun. 2014 Jun 05; 5:4063.Nat Commun2014-06-05T00:00:002014Intramuscular adipogenesis is inhibited by myo-endothelial progenitors with functioning Bmpr1a signalling.Authorship 28146210Authorship 7421881024995979Kong X, Banks A, Liu T, Kazak L, Rao RR, Cohen P, Wang X, Yu S, Lo JC, Tseng YH, Cypess AM, Xue R, Kleiner S, Kang S, Spiegelman BM, Rosen EDCellIRF4 is a key thermogenic transcriptional partner of PGC-1a. Cell. 2014 Jul 03; 158(1):69-83.Cell2014-07-03T00:00:002014IRF4 is a key thermogenic transcriptional partner of PGC-1a.Authorship 3779861Authorship 4878231Authorship 7510021125080478Ussar S, Lee KY, Dankel SN, Boucher J, Haering MF, Kleinridders A, Thomou T, Xue R, Macotela Y, Cypess AM, Tseng YH, Mellgren G, Kahn CRScience translational medicineASC-1, PAT2, and P2RX5 are cell surface markers for white, beige, and brown adipocytes. Sci Transl Med. 2014 Jul 30; 6(247):247ra103.Sci Transl Med2014-07-30T00:00:002014ASC-1, PAT2, and P2RX5 are cell surface markers for white, beige, and brown adipocytes.Authorship 5282532Authorship 762404225261553Lynes MD, Tseng YHProceedings of the National Academy of Sciences of the United States of AmericaUnwiring the transcriptional heat circuit. Proc Natl Acad Sci U S A. 2014 Oct 07; 111(40):14318-9.Proc Natl Acad Sci U S A2014-09-26T00:00:002014Unwiring the transcriptional heat circuit.Authorship 4058052Authorship 4072532Authorship 3784841Authorship 499761325605808Stanford KI, Middelbeek RJ, Townsend KL, Lee MY, Takahashi H, So K, Hitchcox KM, Markan KR, Hellbach K, Hirshman MF, Tseng YH, Goodyear LJDiabetesA novel role for subcutaneous adipose tissue in exercise-induced improvements in glucose homeostasis. Diabetes. 2015 Jun; 64(6):2002-14.Diabetes2015-01-20T00:00:002015A novel role for subcutaneous adipose tissue in exercise-induced improvements in glucose homeostasis.Authorship 5344664Authorship 3977441Authorship 4295493Authorship 711004Authorship 24065711Authorship 3284526Authorship 79079211Authorship 801694425625589Lynes MD, Schulz TJ, Pan AJ, Tseng YHEndocrinologyDisruption of insulin signaling in Myf5-expressing progenitors leads to marked paucity of brown fat but normal muscle development. Endocrinology. 2015 May; 156(5):1637-47.Endocrinology2015-01-27T00:00:002015Disruption of insulin signaling in Myf5-expressing progenitors leads to marked paucity of brown fat but normal muscle development.Authorship 29832Authorship 8149961726076036Xue R, Lynes MD, Dreyfuss JM, Shamsi F, Schulz TJ, Zhang H, Huang TL, Townsend KL, Li Y, Takahashi H, Weiner LS, White AP, Lynes MS, Rubin LL, Goodyear LJ, Cypess AM, Tseng YHNature medicineClonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes. Nat Med. 2015 Jul; 21(7):760-8.Nat Med2015-06-15T00:00:002015Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes.Authorship 824081826269357Zhang X, Tian Y, Zhang H, Kavishwar A, Lynes M, Brownell AL, Sun H, Tseng YH, Moore A, Ran CScientific reportsCurcumin analogues as selective fluorescence imaging probes for brown adipose tissue and monitoring browning. Sci Rep. 2015 Aug 13; 5:13116.Sci Rep2015-08-13T00:00:002015Curcumin analogues as selective fluorescence imaging probes for brown adipose tissue and monitoring browning.Authorship 8389671726303948Zhang H, Guan M, Townsend KL, Huang TL, An D, Yan X, Xue R, Schulz TJ, Winnay J, Mori M, Hirshman MF, Kristiansen K, Tsang JS, White AP, Cypess AM, Goodyear LJ, Tseng YHEMBO reportsMicroRNA-455 regulates brown adipogenesis via a novel HIF1an-AMPK-PGC1a signaling network. EMBO Rep. 2015 Oct; 16(10):1378-93.EMBO Rep2015-08-24T00:00:002015MicroRNA-455 regulates brown adipogenesis via a novel HIF1an-AMPK-PGC1a signaling network.26801556Jeong HW, Choi RH, McClellan JL, Piroli GG, Frizzell N, Tseng YH, Goodyear LJ, Koh HJBiochemical and biophysical research communicationsTribbles 3 inhibits brown adipocyte differentiation and function by suppressing insulin signaling. Biochem Biophys Res Commun. 2016 Feb 19; 470(4):783-91.Biochem Biophys Res Commun2016-01-20T00:00:002016Tribbles 3 inhibits brown adipocyte differentiation and function by suppressing insulin signaling.2Assistant Professor1Associate Professor0Full Professor27209464Schulz TJ, Graja A, Huang TL, Xue R, An D, Poehle-Kronawitter S, Lynes MD, Tolkachov A, O'Sullivan LE, Hirshman MF, Schupp M, Goodyear LJ, Mishina Y, Tseng YHDiabetologiaLoss of BMP receptor type 1A in murine adipose tissue attenuates age-related onset of insulin resistance. Diabetologia. 2016 08; 59(8):1769-77.Diabetologia2016-05-21T00:00:002016Loss of BMP receptor type 1A in murine adipose tissue attenuates age-related onset of insulin resistance.27548241Gao F, McDaniel J, Chen EY, Rockwell H, Lynes MD, Tseng YH, Sarangarajan R, Narain NR, Kiebish MAMetabolitesMonoacylglycerol Analysis Using MS/MS(ALL) Quadruple Time of Flight Mass Spectrometry. Metabolites. 2016 Aug 17; 6(3).Metabolites2016-08-17T00:00:002016Monoacylglycerol Analysis Using MS/MS(ALL) Quadruple Time of Flight Mass Spectrometry.2007-03-31TSENG, YU-HUA2005-04-01Role of BMPs on Brown Adipogenesis and ThermogenesisR21DK0707222004-02-29TSENG, YU-HUA2001-03-01ROLE OF INSULIN AND IGF-1 ON BROWN ADIPOCYTESF32DK0101832025-03-31TSENG, YU-HUA2015-07-03Fibroblast Growth Factor and Energy MetabolismR01DK1028982021-04-30TSENG, YU-HUA2006-12-01Regulation of human brown and beige adipocyte differentiation and functionR01DK077097Principal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal Investigator27626200Zhu Y, Gao Y, Tao C, Shao M, Zhao S, Huang W, Yao T, Johnson JA, Liu T, Cypess AM, Gupta O, Holland WL, Gupta RK, Spray DC, Tanowitz HB, Cao L, Lynes MD, Tseng YH, Elmquist JK, Williams KW, Lin HV, Scherer PECell metabolismConnexin 43 Mediates White Adipose Tissue Beiging by Facilitating the Propagation of Sympathetic Neuronal Signals. Cell Metab. 2016 09 13; 24(3):420-433.Cell Metab2016-09-13T00:00:002016Connexin 43 Mediates White Adipose Tissue Beiging by Facilitating the Propagation of Sympathetic Neuronal Signals.Authorship 73759726491708Lynes MD, Tseng YHGenes & diseasesThe Thermogenic Circuit: Regulators of Thermogenic Competency and Differentiation. Genes Dis. 2015 Jun; 2(2):164-172.Genes Dis2015-04-03T00:00:002015The Thermogenic Circuit: Regulators of Thermogenic Competency and Differentiation.Authorship 327292628039752Castiglioni A, Hettmer S, Lynes MD, Rao TN, Tchessalova D, Sinha I, Lee BT, Tseng YH, Wagers AJStem cell reportsIsolation of Progenitors that Exhibit Myogenic/Osteogenic Bipotency In Vitro by Fluorescence-Activated Cell Sorting from Human Fetal Muscle. Stem Cell Reports. 2014 Jan 14; 2(1):92-106.Stem Cell Reports2014-01-14T00:00:002014Isolation of Progenitors that Exhibit Myogenic/Osteogenic Bipotency In Vitro by Fluorescence-Activated Cell Sorting from Human Fetal Muscle.Authorship 4734481Authorship 522746112082100Tseng YH, Ueki K, Kriauciunas KM, Kahn CRThe Journal of biological chemistryDifferential roles of insulin receptor substrates in the anti-apoptotic function of insulin-like growth factor-1 and insulin. J Biol Chem. 2002 Aug 30; 277(35):31601-11.J Biol Chem2002-06-24T00:00:002002Differential roles of insulin receptor substrates in the anti-apoptotic function of insulin-like growth factor-1 and insulin.11280768Tseng YH, Vicent D, Zhu J, Niu Y, Adeyinka A, Moyers JS, Watson PH, Kahn CRCancer researchRegulation of growth and tumorigenicity of breast cancer cells by the low molecular weight GTPase Rad and nm23. Cancer Res. 2001 Mar 01; 61(5):2071-9.Cancer Res2001-03-01T00:00:002001Regulation of growth and tumorigenicity of breast cancer cells by the low molecular weight GTPase Rad and nm23.28244042Shamsi F, Tseng YHMethods in molecular biology (Clifton, N.J.)Protocols for Generation of Immortalized Human Brown and White Preadipocyte Cell Lines. Methods Mol Biol. 2017; 1566:77-85.Methods Mol Biol2017-01-01T00:00:002017Protocols for Generation of Immortalized Human Brown and White Preadipocyte Cell Lines.11784871Ueki K, Fruman DA, Brachmann SM, Tseng YH, Cantley LC, Kahn CRMolecular and cellular biologyMolecular balance between the regulatory and catalytic subunits of phosphoinositide 3-kinase regulates cell signaling and survival. Mol Cell Biol. 2002 Feb; 22(3):965-77.Mol Cell Biol2002-02-01T00:00:002002Molecular balance between the regulatory and catalytic subunits of phosphoinositide 3-kinase regulates cell signaling and survival.28346411Lynes MD, Leiria LO, Lundh M, Bartelt A, Shamsi F, Huang TL, Takahashi H, Hirshman MF, Schlein C, Lee A, Baer LA, May FJ, Gao F, Narain NR, Chen EY, Kiebish MA, Cypess AM, Blüher M, Goodyear LJ, Hotamisligil GS, Stanford KI, Tseng YHNature medicineThe cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue. Nat Med. 2017 May; 23(5):631-637.Nat Med2017-03-27T00:00:002017The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue.16096055Gunton JE, Kulkarni RN, Yim S, Okada T, Hawthorne WJ, Tseng YH, Roberson RS, Ricordi C, O'Connell PJ, Gonzalez FJ, Kahn CRCellLoss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes. Cell. 2005 Aug 12; 122(3):337-49.Cell2005-08-12T00:00:002005Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes.14522909Tai YT, Podar K, Catley L, Tseng YH, Akiyama M, Shringarpure R, Burger R, Hideshima T, Chauhan D, Mitsiades N, Richardson P, Munshi NC, Kahn CR, Mitsiades C, Anderson KCCancer researchInsulin-like growth factor-1 induces adhesion and migration in human multiple myeloma cells via activation of beta1-integrin and phosphatidylinositol 3'-kinase/AKT signaling. 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