"Cell Degranulation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process of losing secretory granules (SECRETORY VESICLES). This occurs, for example, in mast cells, basophils, neutrophils, eosinophils, and platelets when secretory products are released from the granules by EXOCYTOSIS.
Below are MeSH descriptors whose meaning is more general than "Cell Degranulation".
Below are MeSH descriptors whose meaning is more specific than "Cell Degranulation".
This graph shows the total number of publications written about "Cell Degranulation" by people in Harvard Catalyst Profiles by year, and whether "Cell Degranulation" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 4 | 6 |
| 1995 | 2 | 1 | 3 |
| 1996 | 6 | 5 | 11 |
| 1997 | 4 | 11 | 15 |
| 1998 | 1 | 4 | 5 |
| 1999 | 2 | 3 | 5 |
| 2000 | 2 | 3 | 5 |
| 2001 | 0 | 5 | 5 |
| 2002 | 0 | 6 | 6 |
| 2003 | 0 | 4 | 4 |
| 2004 | 1 | 0 | 1 |
| 2005 | 6 | 3 | 9 |
| 2006 | 1 | 1 | 2 |
| 2007 | 1 | 3 | 4 |
| 2008 | 0 | 2 | 2 |
| 2009 | 1 | 4 | 5 |
| 2010 | 1 | 4 | 5 |
| 2011 | 2 | 2 | 4 |
| 2012 | 2 | 4 | 6 |
| 2013 | 4 | 2 | 6 |
| 2014 | 0 | 5 | 5 |
| 2015 | 3 | 2 | 5 |
| 2016 | 2 | 5 | 7 |
| 2017 | 3 | 6 | 9 |
| 2018 | 1 | 3 | 4 |
| 2019 | 2 | 5 | 7 |
| 2020 | 1 | 9 | 10 |
| 2021 | 1 | 1 | 2 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 1 | 1 |
Below are the most recent publications written about "Cell Degranulation" by people in Profiles.
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IgG:Fc?RIIb signals block effector programs of IgE:FceRI-activated mast cells but spare survival pathways. J Allergy Clin Immunol. 2023 08; 152(2):453-468.
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Patient Characteristics Associated With Reactions to Mrgprx2-Activating Drugs in an Electronic Health Record-Linked Biobank. J Allergy Clin Immunol Pract. 2023 02; 11(2):492-499.e2.
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TLR Signaling Rescues Fungicidal Activity in Syk-Deficient Neutrophils. J Immunol. 2022 04 01; 208(7):1664-1674.
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Genetic engineering of porcine endothelial cell lines for evaluation of human-to-pig xenoreactive immune responses. Sci Rep. 2021 06 23; 11(1):13131.
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Constitutive activation of WASp leads to abnormal cytotoxic cells with increased granzyme B and degranulation response to target cells. JCI Insight. 2021 03 22; 6(6).
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How to detect eosinophil ETosis (EETosis) and extracellular traps. Allergol Int. 2021 Jan; 70(1):19-29.
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Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques. Cell. 2021 01 21; 184(2):460-475.e21.
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Amelioration of Compound 48/80-Mediated Itch and LL-37-Induced Inflammation by a Single-Stranded Oligonucleotide. Front Immunol. 2020; 11:559589.
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The Fyn-Stat5 cascade is required for Fc? receptor-mediated mast cell function. Cell Immunol. 2020 10; 356:104134.
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Sialylation of immunoglobulin E is a determinant of allergic pathogenicity. Nature. 2020 06; 582(7811):265-270.