Receptor, Serotonin, 5-HT2B
"Receptor, Serotonin, 5-HT2B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serotonin receptor subtype found in the BRAIN; HEART; LUNGS; PLACENTA and DIGESTIVE SYSTEM organs. A number of functions have been attributed to the action of the 5-HT2B receptor including the development of cardiac myocytes (MYOCYTES, CARDIAC) and the contraction of SMOOTH MUSCLE.
MeSH Number(s)
D12.776.543.750.070.800.200.150
D12.776.543.750.100.800.200.150
D12.776.543.750.720.300.800.200.150
Concept/Terms
Receptor, Serotonin, 5-HT2B- Receptor, Serotonin, 5-HT2B
- 5-HT2B Receptor
- 5 HT2B Receptor
- Receptor, 5-HT2B
- Serotonin 2B Receptors
- 2B Receptors, Serotonin
- Receptors, Serotonin 2B
- Receptor, Serotonin 2B
- 2B Receptor, Serotonin
- Serotonin 2B Receptor
- (5-HT)2B Receptors
- 5-Hydroxytryptamine 2B Receptor
- 2B Receptor, 5-Hydroxytryptamine
- 5 Hydroxytryptamine 2B Receptor
- Receptor, 5-Hydroxytryptamine 2B
Below are MeSH descriptors whose meaning is more general than "Receptor, Serotonin, 5-HT2B".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.070]
- Receptors, Serotonin [D12.776.543.750.070.800]
- Receptors, Serotonin, 5-HT2 [D12.776.543.750.070.800.200]
- Receptor, Serotonin, 5-HT2B [D12.776.543.750.070.800.200.150]
- Receptors, G-Protein-Coupled [D12.776.543.750.100]
- Receptors, Serotonin [D12.776.543.750.100.800]
- Receptors, Serotonin, 5-HT2 [D12.776.543.750.100.800.200]
- Receptor, Serotonin, 5-HT2B [D12.776.543.750.100.800.200.150]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Biogenic Amine [D12.776.543.750.720.300]
- Receptors, Serotonin [D12.776.543.750.720.300.800]
- Receptors, Serotonin, 5-HT2 [D12.776.543.750.720.300.800.200]
- Receptor, Serotonin, 5-HT2B [D12.776.543.750.720.300.800.200.150]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Serotonin, 5-HT2B".
This graph shows the total number of publications written about "Receptor, Serotonin, 5-HT2B" by people in Harvard Catalyst Profiles by year, and whether "Receptor, Serotonin, 5-HT2B" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
Below are the most recent publications written about "Receptor, Serotonin, 5-HT2B" by people in Profiles.
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Inhibiting serotonin signaling through HTR2B in visceral adipose tissue improves obesity-related insulin resistance. J Clin Invest. 2021 12 01; 131(23).
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Translational studies support a role for serotonin 2B receptor (HTR2B) gene in aggression-related cannabis response. Mol Psychiatry. 2018 12; 23(12):2277-2286.
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Classification of Colorectal Cancer in Molecular Subtypes by Immunohistochemistry. Methods Mol Biol. 2018; 1765:179-191.
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Serotonin receptor 2B signaling with interstitial cell activation and leaflet remodeling in degenerative mitral regurgitation. J Mol Cell Cardiol. 2018 02; 115:94-103.
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Discovery of N-Substituted (2-Phenylcyclopropyl)methylamines as Functionally Selective Serotonin 2C Receptor Agonists for Potential Use as Antipsychotic Medications. J Med Chem. 2017 07 27; 60(14):6273-6288.
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Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension. PLoS One. 2016; 11(2):e0148657.
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Genetics of impulsive behaviour. Philos Trans R Soc Lond B Biol Sci. 2013; 368(1615):20120380.
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5-HT(2B) antagonism arrests non-canonical TGF-ß1-induced valvular myofibroblast differentiation. J Mol Cell Cardiol. 2012 Nov; 53(5):707-14.
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Stimulating healthy tissue regeneration by targeting the 5-HT2B receptor in chronic liver disease. Nat Med. 2011 Nov 27; 17(12):1668-73.
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Serotonin receptors and heart valve disease--it was meant 2B. Pharmacol Ther. 2011 Nov; 132(2):146-57.