PC12 Cells

"PC12 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A CELL LINE derived from a PHEOCHROMOCYTOMA of the rat ADRENAL MEDULLA. PC12 cells stop dividing and undergo terminal differentiation when treated with NERVE GROWTH FACTOR, making the line a useful model system for NERVE CELL differentiation.

Descriptor ID

D016716

MeSH Number(s)

A11.251.210.190.750

A11.251.860.180.750

A11.299.500

Concept/Terms

PC12 Cells

Below are MeSH descriptors whose meaning is more general than "PC12 Cells".

Anatomy [A]
Cells [A11]
Cells, Cultured [A11.251]
Cell Line [A11.251.210]
Cell Line, Tumor [A11.251.210.190]
PC12 Cells [A11.251.210.190.750]
Tumor Cells, Cultured [A11.251.860]
Cell Line, Tumor [A11.251.860.180]
PC12 Cells [A11.251.860.180.750]
Chromaffin Cells [A11.299]
PC12 Cells [A11.299.500]

Below are MeSH descriptors whose meaning is related to "PC12 Cells".

Below are MeSH descriptors whose meaning is more specific than "PC12 Cells".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "PC12 Cells" by people in Harvard Catalyst Profiles by year, and whether "PC12 Cells" was a major or minor topic of these publication.

Bar chart showing 247 publications over 28 distinct years, with a maximum of 21 publications in 2003

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	13	13
1995	0	15	15
1996	0	10	10
1997	1	8	9
1998	0	12	12
1999	1	8	9
2000	0	19	19
2001	1	9	10
2002	0	10	10
2003	2	19	21
2004	0	4	4
2005	0	10	10
2006	1	8	9
2007	0	10	10
2008	0	8	8
2009	0	9	9
2010	0	3	3
2011	0	9	9
2012	0	9	9
2013	0	7	7
2014	0	6	6
2015	0	6	6
2016	0	4	4
2017	0	3	3
2018	0	11	11
2019	0	7	7
2020	0	2	2
2021	0	2	2

Below are the most recent publications written about "PC12 Cells" by people in Profiles.

Antiproliferative effects of metformin in cellular models of pheochromocytoma. Mol Cell Endocrinol. 2022 01 01; 539:111484.

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Glucocorticoids attenuate interleukin-6-induced c-Fos and Egr1 expression and impair neuritogenesis in PC12 cells. J Neurochem. 2021 05; 157(3):532-549.

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Distinct insulin granule subpopulations implicated in the secretory pathology of diabetes types 1 and 2. Elife. 2020 11 09; 9.

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Synaptotagmin-7 enhances calcium-sensing of chromaffin cell granules and slows discharge of granule cargos. J Neurochem. 2020 09; 154(6):598-617.

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The high-affinity IgG receptor Fc?RI modulates peripheral nerve injury-induced neuropathic pain in rats. Mol Brain. 2019 10 22; 12(1):83.

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In vitro fusion of single synaptic and dense core vesicles reproduces key physiological properties. Nat Commun. 2019 08 29; 10(1):3904.

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Stress-induced phospho-ubiquitin formation causes parkin degradation. Sci Rep. 2019 08 12; 9(1):11682.

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EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance. Proc Natl Acad Sci U S A. 2019 08 20; 116(34):16997-17006.

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In Silico Approach for Designing Potent Neuroprotective Hexapeptide. ACS Chem Neurosci. 2019 06 19; 10(6):3018-3030.

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Morphometric and computational assessments to evaluate neuron survival and maturation within compartmentalized microfluidic devices: The influence of design variation on diffusion-driven nutrient transport. Neurosci Lett. 2019 06 11; 703:58-67.

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