Integrin alpha2

"Integrin alpha2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An integrin alpha subunit that primarily combines with INTEGRIN BETA1 to form the INTEGRIN ALPHA2BETA1 heterodimer. It contains a domain which has homology to collagen-binding domains found in von Willebrand factor.

Descriptor ID

D039421

MeSH Number(s)

D12.776.543.750.705.408.100.350

D23.050.301.264.035.287

D23.101.100.110.288

Concept/Terms

Integrin alpha2

Below are MeSH descriptors whose meaning is more general than "Integrin alpha2".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Immunologic [D12.776.543.750.705]
Integrins [D12.776.543.750.705.408]
Integrin alpha Chains [D12.776.543.750.705.408.100]
Integrin alpha2 [D12.776.543.750.705.408.100.350]
Biological Factors [D23]
Antigens [D23.050]
Antigens, Surface [D23.050.301]
Antigens, Differentiation [D23.050.301.264]
Antigens, CD [D23.050.301.264.035]
Integrin alpha2 [D23.050.301.264.035.287]
Biological Markers [D23.101]
Antigens, Differentiation [D23.101.100]
Antigens, CD [D23.101.100.110]
Integrin alpha2 [D23.101.100.110.288]

Below are MeSH descriptors whose meaning is related to "Integrin alpha2".

Below are MeSH descriptors whose meaning is more specific than "Integrin alpha2".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Integrin alpha2" by people in Harvard Catalyst Profiles by year, and whether "Integrin alpha2" was a major or minor topic of these publication.

Bar chart showing 26 publications over 17 distinct years, with a maximum of 4 publications in 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	2	2
1997	0	1	1
1998	0	2	2
2001	0	1	1
2002	0	1	1
2005	1	0	1
2006	1	0	1
2009	1	1	2
2011	1	0	1
2012	1	0	1
2014	0	1	1
2015	1	2	3
2016	0	2	2
2017	0	1	1
2019	1	0	1
2022	2	2	4
2023	0	1	1

Below are the most recent publications written about "Integrin alpha2" by people in Profiles.

Differentiated neuroblastoma cells remain epigenetically poised for de-differentiation to an immature state. Dis Model Mech. 2023 Dec 01; 16(12).

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CD49b identifies functionally and epigenetically distinct subsets of lineage-biased hematopoietic stem cells. Stem Cell Reports. 2022 07 12; 17(7):1546-1560.

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Exploratory Use of Glycoprotein IIb/IIIa Inhibition in Prevention of Blalock-Taussig Shunt Thrombosis. Pediatr Crit Care Med. 2022 09 01; 23(9):727-735.

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Overexpression of integrin alpha 2 (ITGA2) correlates with poor survival in patients with pancreatic ductal adenocarcinoma. J Clin Pathol. 2023 Aug; 76(8):541-547.

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Adult enteric Dclk1-positive glial and neuronal cells reveal distinct responses to acute intestinal injury. Am J Physiol Gastrointest Liver Physiol. 2022 06 01; 322(6):G583-G597.

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ITGA2 as a potential nanotherapeutic target for glioblastoma. Sci Rep. 2019 04 17; 9(1):6195.

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Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition. Mol Cell. 2017 Aug 03; 67(3):512-527.e4.

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The aryl hydrocarbon receptor is required for the maintenance of liver-resident natural killer cells. J Exp Med. 2016 10 17; 213(11):2249-2257.

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A pilot study showing associations between frequency of CD4(+) memory cell subsets at diagnosis and duration of partial remission in type 1 diabetes. Clin Immunol. 2016 05; 166-167:72-80.

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ß-Subunit Binding Is Sufficient for Ligands to Open the Integrin aIIbß3 Headpiece. J Biol Chem. 2016 Feb 26; 291(9):4537-46.

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