Desensitization, Immunologic
"Desensitization, Immunologic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Immunosuppression by the administration of increasing doses of antigen. Though the exact mechanism is not clear, the therapy results in an increase in serum levels of allergen-specific IMMUNOGLOBULIN G, suppression of specific IgE, and an increase in suppressor T-cell activity.
MeSH Number(s)
E02.095.465.425.450.310
E05.478.610.310
Concept/Terms
Desensitization, Immunologic- Desensitization, Immunologic
- Immunologic Desensitization
- Desensitizations, Immunologic
- Immunologic Desensitizations
- Therapy, Hyposensitization
- Hyposensitization Therapies
- Therapies, Hyposensitization
- Hyposensitization Therapy
Allergen Immunotherapy- Allergen Immunotherapy
- Allergen Immunotherapies
- Immunotherapies, Allergen
- Immunotherapy, Allergen
Below are MeSH descriptors whose meaning is more general than "Desensitization, Immunologic".
Below are MeSH descriptors whose meaning is more specific than "Desensitization, Immunologic".
This graph shows the total number of publications written about "Desensitization, Immunologic" by people in Harvard Catalyst Profiles by year, and whether "Desensitization, Immunologic" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 3 | 1 | 4 |
| 1995 | 3 | 0 | 3 |
| 1996 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 1 | 2 |
| 2002 | 0 | 1 | 1 |
| 2004 | 4 | 0 | 4 |
| 2005 | 3 | 1 | 4 |
| 2006 | 3 | 0 | 3 |
| 2007 | 1 | 0 | 1 |
| 2008 | 4 | 0 | 4 |
| 2009 | 7 | 1 | 8 |
| 2010 | 7 | 3 | 10 |
| 2011 | 5 | 3 | 8 |
| 2012 | 10 | 2 | 12 |
| 2013 | 6 | 5 | 11 |
| 2014 | 14 | 5 | 19 |
| 2015 | 9 | 7 | 16 |
| 2016 | 15 | 2 | 17 |
| 2017 | 15 | 5 | 20 |
| 2018 | 18 | 5 | 23 |
| 2019 | 18 | 11 | 29 |
| 2020 | 7 | 14 | 21 |
| 2021 | 8 | 10 | 18 |
| 2022 | 4 | 11 | 15 |
| 2023 | 1 | 6 | 7 |
| 2024 | 1 | 0 | 1 |
Below are the most recent publications written about "Desensitization, Immunologic" by people in Profiles.
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Omalizumab for the Treatment of Multiple Food Allergies. N Engl J Med. 2024 03 07; 390(10):889-899.
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Differential presentation of hypersensitivity reactions to carboplatin and oxaliplatin: Phenotypes, endotypes, and management with desensitization. Allergy. 2024 Mar; 79(3):679-689.
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Should Biologics Be Used Before Aspirin Desensitization in Aspirin-Exacerbated Respiratory Disease? J Allergy Clin Immunol Pract. 2024 01; 12(1):79-84.
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Progestogen Hypersensitivity. J Allergy Clin Immunol Pract. 2023 12; 11(12):3606-3613.e2.
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Co-treatment of non-steroidal anti-inflammatory drug-exacerbated respiratory disease with dupilumab and aspirin therapy after desensitization. Clin Exp Allergy. 2023 09; 53(9):974-977.
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Phase 3 Trial of Epicutaneous Immunotherapy in Toddlers with Peanut Allergy. N Engl J Med. 2023 May 11; 388(19):1755-1766.
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Distinct trajectories distinguish antigen-specific T cells in peanut-allergic individuals undergoing oral immunotherapy. J Allergy Clin Immunol. 2023 07; 152(1):155-166.e9.
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Immunotherapy-induced neutralizing antibodies disrupt allergen binding and sustain allergen tolerance in peanut allergy. J Clin Invest. 2023 01 17; 133(2).
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Utilizing Biologics in Drug Desensitization. Curr Allergy Asthma Rep. 2023 01; 23(1):1-11.
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Extrapolating Evidence-Based Medicine of AIT Into Clinical Practice in the United States. J Allergy Clin Immunol Pract. 2023 04; 11(4):1100-1115.