Antigens, CD40

"Antigens, CD40" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A member of the tumor necrosis factor receptor superfamily with specificity for CD40 LIGAND. It is found on mature B-LYMPHOCYTES and some EPITHELIAL CELLS, lymphoid DENDRITIC CELLS. Evidence suggests that CD40-dependent activation of B-cells is important for generation of memory B-cells within the germinal centers. Mutations of the gene for CD40 antigen result in HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 3. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.

Descriptor ID

D019013

MeSH Number(s)

D12.776.543.750.705.852.760.097

D23.050.301.264.035.140

D23.050.301.264.051.140

D23.101.100.110.140

D23.101.100.150.140

Concept/Terms

Antigens, CD40

Below are MeSH descriptors whose meaning is more general than "Antigens, CD40".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Cytokine [D12.776.543.750.705.852]
Receptors, Tumor Necrosis Factor [D12.776.543.750.705.852.760]
Antigens, CD40 [D12.776.543.750.705.852.760.097]
Biological Factors [D23]
Antigens [D23.050]
Antigens, Surface [D23.050.301]
Antigens, Differentiation [D23.050.301.264]
Antigens, CD [D23.050.301.264.035]
Antigens, CD40 [D23.050.301.264.035.140]
Antigens, Differentiation, B-Lymphocyte [D23.050.301.264.051]
Antigens, CD40 [D23.050.301.264.051.140]
Biological Markers [D23.101]
Antigens, Differentiation [D23.101.100]
Antigens, CD [D23.101.100.110]
Antigens, CD40 [D23.101.100.110.140]
Antigens, Differentiation, B-Lymphocyte [D23.101.100.150]
Antigens, CD40 [D23.101.100.150.140]

Below are MeSH descriptors whose meaning is related to "Antigens, CD40".

Below are MeSH descriptors whose meaning is more specific than "Antigens, CD40".

publications

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