"Peroxisome Proliferators" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of nongenotoxic CARCINOGENS that induce the production of hepatic PEROXISOMES and induce hepatic neoplasms after long-term administration.
Below are MeSH descriptors whose meaning is more general than "Peroxisome Proliferators".
Below are MeSH descriptors whose meaning is more specific than "Peroxisome Proliferators".
This graph shows the total number of publications written about "Peroxisome Proliferators" by people in Harvard Catalyst Profiles by year, and whether "Peroxisome Proliferators" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1999 | 0 | 1 | 1 |
2001 | 1 | 0 | 1 |
2002 | 1 | 2 | 3 |
2014 | 1 | 0 | 1 |
Below are the most recent publications written about "Peroxisome Proliferators" by people in Profiles.
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Long non-coding RNA Gm15441 attenuates hepatic inflammasome activation in response to PPARA agonism and fasting. Nat Commun. 2020 11 17; 11(1):5847.
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Hepatocyte-specific PPARA expression exclusively promotes agonist-induced cell proliferation without influence from nonparenchymal cells. Am J Physiol Gastrointest Liver Physiol. 2017 Mar 01; 312(3):G283-G299.
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Effects of the environmental contaminants DEHP and TCDD on estradiol synthesis and aryl hydrocarbon receptor and peroxisome proliferator-activated receptor signalling in the human granulosa cell line KGN. Mol Hum Reprod. 2014 Sep; 20(9):919-28.
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Hepatic oxidative stress activates the Gadd45b gene by way of degradation of the transcriptional repressor STAT3. Hepatology. 2014 Feb; 59(2):695-704.
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PPARalpha-dependent activation of cell cycle control and DNA repair genes in hepatic nonparenchymal cells. Toxicol Sci. 2010 Dec; 118(2):404-10.
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Effect of prenatal peroxisome proliferator-activated receptor alpha (PPARalpha) agonism on postnatal development. Toxicology. 2010 Sep 30; 276(1):79-84.
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Control of steroid 21-oic acid synthesis by peroxisome proliferator-activated receptor alpha and role of the hypothalamic-pituitary-adrenal axis. J Biol Chem. 2010 Mar 05; 285(10):7670-85.
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PPARalpha: mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators. Toxicology. 2008 Apr 03; 246(1):2-8.
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Metabolomic and genetic analysis of biomarkers for peroxisome proliferator-activated receptor alpha expression and activation. Mol Endocrinol. 2007 Sep; 21(9):2136-51.
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Peroxisome proliferator-activated receptor alpha regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation. Mol Cell Biol. 2007 Jun; 27(12):4238-47.