Bulbar Palsy, Progressive
"Bulbar Palsy, Progressive" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A motor neuron disease marked by progressive weakness of the muscles innervated by cranial nerves of the lower brain stem. Clinical manifestations include dysarthria, dysphagia, facial weakness, tongue weakness, and fasciculations of the tongue and facial muscles. The adult form of the disease is marked initially by bulbar weakness which progresses to involve motor neurons throughout the neuroaxis. Eventually this condition may become indistinguishable from AMYOTROPHIC LATERAL SCLEROSIS. Fazio-Londe syndrome is an inherited form of this illness which occurs in children and young adults. (Adams et al., Principles of Neurology, 6th ed, p1091; Brain 1992 Dec;115(Pt 6):1889-1900)
MeSH Number(s)
C10.574.562.300
C10.668.467.300
Concept/Terms
Bulbar Palsy, Progressive- Bulbar Palsy, Progressive
- Bulbar Palsies, Progressive
- Palsies, Progressive Bulbar
- Palsy, Progressive Bulbar
- Progressive Bulbar Palsies
- Progressive Bulbar Palsy
- Paralysis, Bulbar
- Bulbar Paralyses
- Bulbar Paralysis
- Bulbar Palsy
- Bulbar Palsies
- Palsies, Bulbar
- Palsy, Bulbar
Below are MeSH descriptors whose meaning is more general than "Bulbar Palsy, Progressive".
Below are MeSH descriptors whose meaning is more specific than "Bulbar Palsy, Progressive".
This graph shows the total number of publications written about "Bulbar Palsy, Progressive" by people in Harvard Catalyst Profiles by year, and whether "Bulbar Palsy, Progressive" was a major or minor topic of these publication.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2012 | 2 | 0 | 2 |
| 2018 | 0 | 1 | 1 |
Below are the most recent publications written about "Bulbar Palsy, Progressive" by people in Profiles.
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Clinical Reasoning: Young adult with dysphagia and severe weight loss. Neurology. 2018 09 11; 91(11):e1083-e1086.
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SLC52A3, A Brown-Vialetto-van Laere syndrome candidate gene is essential for mouse development, but dispensable for motor neuron differentiation. Hum Mol Genet. 2016 05 01; 25(9):1814-23.
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Human T-lymphotropic virus type-I (HTLV-I)-associated myelopathy with bulbar palsy-type amyotrophic lateral sclerosis-like symptoms. Intern Med. 2015; 54(9):1105-7.
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Treatable childhood neuronopathy caused by mutations in riboflavin transporter RFVT2. Brain. 2014 Jan; 137(Pt 1):44-56.
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Brown-Vialetto-Van Laere syndrome: clinical and neuroradiological findings of a genetically proven patient. Amyotroph Lateral Scler Frontotemporal Degener. 2014 Mar; 15(1-2):141-4.
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A novel compound heterozygous mutation of C20orf54 gene associated with Brown-Vialetto-Van Laere syndrome in an Italian family. Eur J Neurol. 2013 Jul; 20(7):e94-5.
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Brown-Vialetto-Van Laere and Fazio Londe syndromes: defects of riboflavin transport with biochemical similarities to multiple acyl-CoA dehydrogenation defects (MADD). J Inherit Metab Dis. 2012 Nov; 35(6):941-2.
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Association of UBQLN1 mutation with Brown-Vialetto-Van Laere syndrome but not typical ALS. Neurobiol Dis. 2012 Dec; 48(3):391-8.
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A protocol for comprehensive assessment of bulbar dysfunction in amyotrophic lateral sclerosis (ALS). J Vis Exp. 2011 Feb 21; (48).
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The clinical course of progressive bulbar palsy. Amyotroph Lateral Scler. 2010 Aug; 11(4):364-8.