Large-Conductance Calcium-Activated Potassium Channels
"Large-Conductance Calcium-Activated Potassium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A major class of calcium activated potassium channels whose members are voltage-dependent. MaxiK channels are activated by either membrane depolarization or an increase in intracellular Ca(2+). They are key regulators of calcium and electrical signaling in a variety of tissues.
MeSH Number(s)
D12.776.157.530.400.600.150.500
D12.776.543.550.425.750.150.500
D12.776.543.585.400.750.150.500
Below are MeSH descriptors whose meaning is more general than "Large-Conductance Calcium-Activated Potassium Channels".
Below are MeSH descriptors whose meaning is more specific than "Large-Conductance Calcium-Activated Potassium Channels".
This graph shows the total number of publications written about "Large-Conductance Calcium-Activated Potassium Channels" by people in Harvard Catalyst Profiles by year, and whether "Large-Conductance Calcium-Activated Potassium Channels" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1999 | 0 | 1 | 1 |
2000 | 0 | 1 | 1 |
2003 | 0 | 2 | 2 |
2005 | 1 | 0 | 1 |
2006 | 1 | 1 | 2 |
2007 | 1 | 0 | 1 |
2008 | 0 | 1 | 1 |
2009 | 1 | 1 | 2 |
2011 | 1 | 0 | 1 |
2013 | 3 | 0 | 3 |
2014 | 2 | 0 | 2 |
2015 | 2 | 0 | 2 |
2018 | 1 | 0 | 1 |
2019 | 0 | 1 | 1 |
2020 | 1 | 1 | 2 |
2021 | 1 | 0 | 1 |
2022 | 1 | 0 | 1 |
Below are the most recent publications written about "Large-Conductance Calcium-Activated Potassium Channels" by people in Profiles.
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Discovery of Novel Activators of Large-Conductance Calcium-Activated Potassium Channels for the Treatment of Cerebellar Ataxia. Mol Pharmacol. 2022 07; 102(1):438-449.
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Shank promotes action potential repolarization by recruiting BK channels to calcium microdomains. Elife. 2022 03 10; 11.
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BK Channel Regulation of Afterpotentials and Burst Firing in Cerebellar Purkinje Neurons. J Neurosci. 2021 03 31; 41(13):2854-2869.
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Neuronal Inactivity Co-opts LTP Machinery to Drive Potassium Channel Splicing and Homeostatic Spike Widening. Cell. 2020 06 25; 181(7):1547-1565.e15.
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Functional Postnatal Maturation of the Medial Olivocochlear Efferent-Outer Hair Cell Synapse. J Neurosci. 2020 06 17; 40(25):4842-4857.
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Zileuton, a 5-Lipoxygenase Inhibitor, Exerts Anti-Angiogenic Effect by Inducing Apoptosis of HUVEC via BK Channel Activation. Cells. 2019 09 30; 8(10).
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Defective Tmprss3-Associated Hair Cell Degeneration in Inner Ear Organoids. Stem Cell Reports. 2019 07 09; 13(1):147-162.
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CRL4 antagonizes SCFFbxo7-mediated turnover of cereblon and BK channel to regulate learning and memory. PLoS Genet. 2018 01; 14(1):e1007165.
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Differential Regulation of Action Potential Shape and Burst-Frequency Firing by BK and Kv2 Channels in Substantia Nigra Dopaminergic Neurons. J Neurosci. 2015 Dec 16; 35(50):16404-17.
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Calcium activated K? channels in the electroreceptor of the skate confirmed by cloning. Details of subunits and splicing. Gene. 2016 Mar 01; 578(1):63-73.