Cytochrome P-450 CYP2E1

"Cytochrome P-450 CYP2E1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An ethanol-inducible cytochrome P450 enzyme that metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Substrates include alcohol; NITROSAMINES; BENZENE; URETHANE; and other low molecular weight compounds. CYP2E1 has been used as an enzyme marker in the study of alcohol abuse.

Descriptor ID

D019392

MeSH Number(s)

D08.244.453.040.972

D08.811.682.662.582.338

D08.811.682.690.708.170.040.777

D12.776.422.220.453.040.944

Concept/Terms

Cytochrome P-450 CYP2E1

Below are MeSH descriptors whose meaning is more general than "Cytochrome P-450 CYP2E1".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Cytochromes [D08.244]
Cytochrome P-450 Enzyme System [D08.244.453]
Aryl Hydrocarbon Hydroxylases [D08.244.453.040]
Cytochrome P-450 CYP2E1 [D08.244.453.040.972]
Enzymes [D08.811]
Oxidoreductases [D08.811.682]
Oxidoreductases Acting on CH-NH Group Donors [D08.811.682.662]
Oxidoreductases, N-Demethylating [D08.811.682.662.582]
Cytochrome P-450 CYP2E1 [D08.811.682.662.582.338]
Oxygenases [D08.811.682.690]
Mixed Function Oxygenases [D08.811.682.690.708]
Cytochrome P-450 Enzyme System [D08.811.682.690.708.170]
Aryl Hydrocarbon Hydroxylases [D08.811.682.690.708.170.040]
Cytochrome P-450 CYP2E1 [D08.811.682.690.708.170.040.777]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Hemeproteins [D12.776.422]
Cytochromes [D12.776.422.220]
Cytochrome P-450 Enzyme System [D12.776.422.220.453]
Aryl Hydrocarbon Hydroxylases [D12.776.422.220.453.040]
Cytochrome P-450 CYP2E1 [D12.776.422.220.453.040.944]

Below are MeSH descriptors whose meaning is more specific than "Cytochrome P-450 CYP2E1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cytochrome P-450 CYP2E1" by people in Harvard Catalyst Profiles by year, and whether "Cytochrome P-450 CYP2E1" was a major or minor topic of these publication.

Bar chart showing 31 publications over 21 distinct years, with a maximum of 4 publications in 2001 and 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	1	1
1995	0	1	1
1998	1	1	2
1999	0	1	1
2001	1	3	4
2002	0	2	2
2003	1	0	1
2005	0	1	1
2006	0	1	1
2008	0	1	1
2010	1	0	1
2011	1	1	2
2012	0	1	1
2014	0	1	1
2015	2	2	4
2016	0	1	1
2017	0	1	1
2018	1	0	1
2020	0	1	1
2022	0	2	2
2023	0	1	1

Below are the most recent publications written about "Cytochrome P-450 CYP2E1" by people in Profiles.

Metabolic Stability of the Demyelination Positron Emission Tomography Tracer [18F]3-Fluoro-4-Aminopyridine and Identification of Its Metabolites. J Pharmacol Exp Ther. 2023 07; 386(1):93-101.

View in: PubMed
Vulvar angiomyofibroblastoma is molecularly defined by recurrent MTG1-CYP2E1 fusions. Histopathology. 2022 Dec; 81(6):841-846.

View in: PubMed
Genetic and pharmacological inhibition of XBP1 protects against APAP hepatotoxicity through the activation of autophagy. Cell Death Dis. 2022 02 10; 13(2):143.

View in: PubMed
snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis. Nature. 2020 11; 587(7832):98-102.

View in: PubMed
The Use of Gapmers for In Vivo Suppression of Hepatic mRNA Targets. Methods Mol Biol. 2020; 2176:177-184.

View in: PubMed
Identification of a Shared Cytochrome p4502E1 Epitope Found in Anesthetic Drug-Induced and Viral Hepatitis. mSphere. 2018 10 10; 3(5).

View in: PubMed
Inhibition of CYP2E1 With Propylene Glycol Does Not Protect Against Hepatocellular Injury in Human Acetaminophen Daily-Dosing Model. J Clin Pharmacol. 2019 01; 59(1):131-138.

View in: PubMed
In drug-induced, immune-mediated hepatitis, interleukin-33 reduces hepatitis and improves survival independently and as a consequence of FoxP3+ T-cell activity. Cell Mol Immunol. 2019 08; 16(8):706-717.

View in: PubMed
Promoter methylation status in genes related with inflammation, nitrosative stress and xenobiotic metabolism in low-level benzene exposure: Searching for biomarkers of oncogenesis. Food Chem Toxicol. 2017 Nov; 109(Pt 1):669-676.

View in: PubMed
Adult mouse model of early hepatocellular carcinoma promoted by alcoholic liver disease. World J Gastroenterol. 2016 Apr 28; 22(16):4091-108.

View in: PubMed

Related Networks

People

Explore

Similar Concepts

Top Journals

Toxicol Appl Pharmacol
Drug Metab Dispos
Biopharm Drug Dispos
Arch Toxicol
Hepatology
PLoS One
J Hepatol
Biochem Pharmacol
Am J Epidemiol
Am J Physiol Endocrinol Metab