Fatigue Syndrome, Chronic
"Fatigue Syndrome, Chronic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18(2):237-42; Ann Intern Med 1994 Dec 15;121(12): 953-9)
MeSH Number(s)
C02.330
C05.651.310
C10.228.440.600
C10.668.364
Concept/Terms
Fatigue Syndrome, Chronic- Fatigue Syndrome, Chronic
- Encephalomyelitis, Myalgic
- Chronic Fatigue Syndrome
- Chronic Fatigue Syndromes
- Fatigue Syndromes, Chronic
- Fatigue Syndrome, Postviral
- Fatigue Syndromes, Postviral
- Postviral Fatigue Syndromes
- Syndromes, Postviral Fatigue
- Chronic Fatigue-Fibromyalgia Syndrome
- Chronic Fatigue Fibromyalgia Syndrome
- Chronic Fatigue-Fibromyalgia Syndromes
- Fatigue-Fibromyalgia Syndrome, Chronic
- Fatigue-Fibromyalgia Syndromes, Chronic
- Syndrome, Chronic Fatigue-Fibromyalgia
- Syndromes, Chronic Fatigue-Fibromyalgia
- Infectious Mononucleosis-Like Syndrome, Chronic
- Infectious Mononucleosis Like Syndrome, Chronic
- Royal Free Disease
- Chronic Fatigue and Immune Dysfunction Syndrome
- Chronic Fatigue Disorder
- Chronic Fatigue Disorders
- Disorders, Chronic Fatigue
- Fatigue Disorder, Chronic
- Fatigue Disorders, Chronic
- Myalgic Encephalomyelitis
- Postviral Fatigue Syndrome
Below are MeSH descriptors whose meaning is more general than "Fatigue Syndrome, Chronic".
Below are MeSH descriptors whose meaning is more specific than "Fatigue Syndrome, Chronic".
This graph shows the total number of publications written about "Fatigue Syndrome, Chronic" by people in Harvard Catalyst Profiles by year, and whether "Fatigue Syndrome, Chronic" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 7 | 0 | 7 |
| 1995 | 6 | 1 | 7 |
| 1996 | 5 | 2 | 7 |
| 1997 | 7 | 0 | 7 |
| 1998 | 4 | 1 | 5 |
| 1999 | 5 | 0 | 5 |
| 2000 | 4 | 0 | 4 |
| 2001 | 3 | 1 | 4 |
| 2002 | 4 | 2 | 6 |
| 2003 | 0 | 1 | 1 |
| 2004 | 7 | 0 | 7 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 3 | 0 | 3 |
| 2008 | 1 | 0 | 1 |
| 2009 | 2 | 0 | 2 |
| 2010 | 3 | 2 | 5 |
| 2011 | 6 | 0 | 6 |
| 2012 | 1 | 0 | 1 |
| 2013 | 3 | 1 | 4 |
| 2014 | 1 | 0 | 1 |
| 2016 | 7 | 0 | 7 |
| 2017 | 3 | 0 | 3 |
| 2018 | 6 | 0 | 6 |
| 2019 | 2 | 1 | 3 |
| 2020 | 3 | 0 | 3 |
| 2021 | 5 | 0 | 5 |
| 2022 | 3 | 0 | 3 |
| 2023 | 7 | 0 | 7 |
| 2024 | 1 | 0 | 1 |
Below are the most recent publications written about "Fatigue Syndrome, Chronic" by people in Profiles.
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Comparison of T-cell receptor diversity of people with myalgic encephalomyelitis versus controls. BMC Res Notes. 2024 Jan 04; 17(1):17.
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Understanding, diagnosing, and treating Myalgic encephalomyelitis/chronic fatigue syndrome - State of the art: Report of the 2nd international meeting at the Charité Fatigue Center. Autoimmun Rev. 2023 Nov; 22(11):103452.
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Myalgic Encephalomyelitis-Chronic Fatigue Syndrome Common Data Element item content analysis. PLoS One. 2023; 18(9):e0291364.
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Anomalies in the review process and interpretation of the evidence in the NICE guideline for chronic fatigue syndrome and myalgic encephalomyelitis. J Neurol Neurosurg Psychiatry. 2023 12; 94(12):1056-1063.
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Exercise Pathophysiology in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Postacute Sequelae of SARS-CoV-2: More in Common Than Not? Chest. 2023 09; 164(3):717-726.
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Long-COVID fatigue is not predicted by pre-pandemic plasma IL-6 levels in mild COVID-19. Inflamm Res. 2023 May; 72(5):947-953.
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Different risk factors distinguish myalgic encephalomyelitis/chronic fatigue syndrome from severe fatigue. Sci Rep. 2023 02 11; 13(1):2469.
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Deficient butyrate-producing capacity in the gut microbiome is associated with bacterial network disturbances and fatigue symptoms in ME/CFS. Cell Host Microbe. 2023 02 08; 31(2):288-304.e8.
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Protracted stress-induced hypocortisolemia may account for the clinical and immune manifestations of Long COVID. Clin Immunol. 2022 12; 245:109133.
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Metabolomic Evidence for Peroxisomal Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Int J Mol Sci. 2022 Jul 18; 23(14).