Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

E-Box Elements

"E-Box Elements" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

DNA locations with the consensus sequence CANNTG. ENHANCER ELEMENTS may contain multiple copies of this element. E-boxes play a regulatory role in the control of transcription. They bind with basic helix-loop-helix (bHLH) type TRANSCRIPTION FACTORS. Binding specificity is determined by the specific bHLH heterodimer or homodimer combination and by the specific nucleotides at the 3rd and 4th position of the E-box sequence.


This graph shows the total number of publications written about "E-Box Elements" by people in Harvard Catalyst Profiles by year, and whether "E-Box Elements" was a major or minor topic of these publication.
Bar chart showing 14 publications over 9 distinct years, with a maximum of 3 publications in 2009
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.