Retinoblastoma-Like Protein p107

"Retinoblastoma-Like Protein p107" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. It contains a conserved pocket region that binds E2F4 TRANSCRIPTION FACTOR and interacts with viral ONCOPROTEINS such as POLYOMAVIRUS TUMOR ANTIGENS; ADENOVIRUS E1A PROTEINS; and PAPILLOMAVIRUS E7 PROTEINS.

Descriptor ID

D050720

MeSH Number(s)

D12.776.624.776.717

D12.776.660.770

D12.776.744.747

Concept/Terms

Retinoblastoma-Like Protein p107

Below are MeSH descriptors whose meaning is more general than "Retinoblastoma-Like Protein p107".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Neoplasm Proteins [D12.776.624]
Tumor Suppressor Proteins [D12.776.624.776]
Retinoblastoma-Like Protein p107 [D12.776.624.776.717]
Nuclear Proteins [D12.776.660]
Retinoblastoma-Like Protein p107 [D12.776.660.770]
Phosphoproteins [D12.776.744]
Retinoblastoma-Like Protein p107 [D12.776.744.747]

Below are MeSH descriptors whose meaning is related to "Retinoblastoma-Like Protein p107".

Below are MeSH descriptors whose meaning is more specific than "Retinoblastoma-Like Protein p107".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Retinoblastoma-Like Protein p107" by people in Harvard Catalyst Profiles by year, and whether "Retinoblastoma-Like Protein p107" was a major or minor topic of these publication.

Bar chart showing 47 publications over 23 distinct years, with a maximum of 6 publications in 2000

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	3	3
1995	0	3	3
1996	0	2	2
1997	0	3	3
1998	0	2	2
2000	0	6	6
2001	0	2	2
2002	0	4	4
2003	0	1	1
2004	0	2	2
2005	1	0	1
2006	0	1	1
2007	0	1	1
2008	1	0	1
2009	1	1	2
2011	0	3	3
2012	0	2	2
2014	0	1	1
2015	0	1	1
2017	2	0	2
2018	0	1	1
2019	1	1	2
2021	0	1	1

Below are the most recent publications written about "Retinoblastoma-Like Protein p107" by people in Profiles.

Germline genetic contribution to the immune landscape of cancer. Immunity. 2021 02 09; 54(2):367-386.e8.

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CRISPR-mediated modeling and functional validation of candidate tumor suppressor genes in small cell lung cancer. Proc Natl Acad Sci U S A. 2020 01 07; 117(1):513-521.

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RB, p130 and p107 differentially repress G1/S and G2/M genes after p53 activation. Nucleic Acids Res. 2019 12 02; 47(21):11197-11208.

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A transient DMSO treatment increases the differentiation potential of human pluripotent stem cells through the Rb family. PLoS One. 2018; 13(12):e0208110.

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Conservation and divergence of C-terminal domain structure in the retinoblastoma protein family. Proc Natl Acad Sci U S A. 2017 05 09; 114(19):4942-4947.

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Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance. Science. 2017 01 06; 355(6320):78-83.

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Regulation of the retinoblastoma-E2F pathway by the ubiquitin-proteasome system. Biochim Biophys Acta. 2015 Oct; 1849(10):1289-97.

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Rb and p107 are required for alpha cell survival, beta cell cycle control and glucagon-like peptide-1 action. Diabetologia. 2014 Dec; 57(12):2555-65.

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Germline mutations in oncogene-induced senescence pathways are associated with multiple sessile serrated adenomas. Gastroenterology. 2014 Feb; 146(2):520-9.

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Mullerian inhibiting substance induces apoptosis of human endometrial stromal cells in endometriosis. J Clin Endocrinol Metab. 2012 Sep; 97(9):3224-30.

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