Coagulase

"Coagulase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Enzymes that cause coagulation in plasma by forming a complex with human PROTHROMBIN. Coagulases are produced by certain STAPHYLOCOCCUS and YERSINIA PESTIS. Staphylococci produce two types of coagulase: Staphylocoagulase, a free coagulase that produces true clotting of plasma, and Staphylococcal clumping factor, a bound coagulase in the cell wall that induces clumping of cells in the presence of fibrinogen.

Descriptor ID

D003030

MeSH Number(s)

D08.811.277.656.300.174

D12.776.097.181

Concept/Terms

Coagulase

Staphylococcus aureus strain 8325-4 of Coagulase

Staphylococcus aureus clone pSCa2 of Coagulase

Staphylococcus aureus strain 213 of Coagulase

Staphylocoagulase

Staphylococcal Clumping Factor

Below are MeSH descriptors whose meaning is more general than "Coagulase".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Peptide Hydrolases [D08.811.277.656]
Endopeptidases [D08.811.277.656.300]
Coagulase [D08.811.277.656.300.174]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Bacterial Proteins [D12.776.097]
Coagulase [D12.776.097.181]

Below are MeSH descriptors whose meaning is related to "Coagulase".

Below are MeSH descriptors whose meaning is more specific than "Coagulase".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Coagulase" by people in Harvard Catalyst Profiles by year, and whether "Coagulase" was a major or minor topic of these publication.

Bar chart showing 22 publications over 17 distinct years, with a maximum of 3 publications in 2007

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
1996	0	1	1
1998	2	0	2
1999	0	1	1
2003	1	0	1
2004	1	0	1
2005	0	1	1
2007	2	1	3
2008	1	0	1
2011	0	1	1
2012	1	0	1
2013	0	1	1
2014	0	1	1
2016	1	1	2
2020	0	2	2
2022	0	1	1
2023	1	0	1

Below are the most recent publications written about "Coagulase" by people in Profiles.

Associations of Standard Care, Intrathecal Antibiotics, and Antibiotic-Impregnated Catheters With Cerebrospinal Fluid Shunt Infection Organisms and Resistance. J Pediatric Infect Dis Soc. 2023 Sep 27; 12(9):504-512.

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Indolent Infection After Lumbar Interbody Fusion: An Under-recognized Cause of Pseudarthrosis, Which Can Be Successfully Treated With Anterior Revision Fusion. J Am Acad Orthop Surg Glob Res Rev. 2022 03 02; 6(3).

View in: PubMed
Multimodal imaging of bacterial-host interface in mice and piglets with Staphylococcus aureus endocarditis. Sci Transl Med. 2020 11 04; 12(568).

View in: PubMed
The End of Coagulase-Negative Staphylococci? A Micro-Comic Strip. J Clin Microbiol. 2020 02 24; 58(3).

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Review of Clinically and Epidemiologically Relevant Coagulase-Negative Staphylococci in Africa. Microb Drug Resist. 2020 Aug; 26(8):951-970.

View in: PubMed
Pediatric Musculoskeletal Infection: Hijacking the Acute-Phase Response. JBJS Rev. 2016 09 27; 4(9).

View in: PubMed
Preclinical Efficacy of Clumping Factor A in Prevention of Staphylococcus aureus Infection. mBio. 2016 Feb 02; 7(1):e02232-15.

View in: PubMed
Technical note: a pilot study using a mouse mastitis model to study differences between bovine associated coagulase-negative staphylococci. J Dairy Sci. 2015 Feb; 98(2):1090-100.

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Coagulase-negative staphylococcal bloodstream and prosthetic-device-associated infections: the role of biofilm formation and distribution of adhesin and toxin genes. J Med Microbiol. 2014 Nov; 63(Pt 11):1500-1508.

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Factors influencing linezolid-nonsusceptible coagulase-negative staphylococci dissemination among patients in the intensive care unit: a retrospective cohort study. Chemotherapy. 2013; 59(6):420-6.

View in: PubMed

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