D013107Chemicals & DrugsD10.570.877D10.8081111600.880201Sphingolipidscatalyst:eCommonsLogineCommons LoginFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentDivisionvivo:hrJobTitleHR job titleInformation ResourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson1.909980.00883663111research area of0.9797130.0172586161subject area forMedicineNeurologyPediatricsSurgeryChanning Division of Network MedicineBrigham and Women's HospitalBoston Children's HospitalMassachusetts General HospitalSTW1ScottWeissScott Tillman Weiss, M.D.42.33669100000000-71.1020890000000050689Weiss, ScottProfessor of MedicineFE6FlorianEichlerFlorian Eichler, M.D.42.36241700000000-71.0689370000000083582Eichler, FlorianProfessor of Neurologytrue1Assistant Professor of MedicineAssistant Professor of Medicine34303789Savira F, Magaye R, Scullino CV, Flynn BL, Pitson SM, Anderson D, Creek DJ, Hua Y, Xiong X, Huang L, Liew D, Reid C, Kaye D, Kompa AR, Wang BHToxicology lettersSphingolipid imbalance and inflammatory effects induced by uremic toxins in heart and kidney cells are reversed by dihydroceramide desaturase 1 inhibition. Toxicol Lett. 2021 Oct 10; 350:133-142.Toxicol Lett2021-07-22T00:00:002021Sphingolipid imbalance and inflammatory effects induced by uremic toxins in heart and kidney cells are reversed by dihydroceramide desaturase 1 inhibition.36197001Kuo A, Checa A, Niaudet C, Jung B, Fu Z, Wheelock CE, Singh SA, Aikawa M, Smith LE, Proia RL, Hla TeLifeMurine endothelial serine palmitoyltransferase 1 (SPTLC1) is required for vascular development and systemic sphingolipid homeostasis. Elife. 2022 Oct 05; 11.Elife2022-10-05T00:00:002022Murine endothelial serine palmitoyltransferase 1 (SPTLC1) is required for vascular development and systemic sphingolipid homeostasis.true1Professor of NeurologyProfessor of NeurologyPrecision Vaccinessat929SanyaThomasSanya Thomas, M.D.198911Thomas, SanyaResearch Fellow in Pediatrics37084874Nicholas SE, Choi AJ, Lam TN, Basu SK, Mandal N, Karamichos DExperimental eye researchPotentiation of Sphingolipids and TGF-ß in the human corneal stroma reveals intricate signaling pathway crosstalks. Exp Eye Res. 2023 06; 231:109487.Exp Eye Res2023-04-19T00:00:002023Potentiation of Sphingolipids and TGF-ß in the human corneal stroma reveals intricate signaling pathway crosstalks.38014461Chen Y, Checa A, Zhang P, Huang M, Kelly RS, Kim M, Chen YS, Lee-Sarwar KA, Prince N, Mendez KM, Begum S, Kachroo P, Chu SH, Stokholm J, Bønnelykke K, Litonjua AA, Bisgaard H, Weiss ST, Chawes BL, Wheelock CE, Lasky-Su JAAllergySphingolipid classes and the interrelationship with pediatric asthma and asthma risk factors. Allergy. 2024 Feb; 79(2):404-418.Allergy2023-11-28T00:00:002023Sphingolipid classes and the interrelationship with pediatric asthma and asthma risk factors.38139132Thomas S, Samuel SV, Hoch A, Syphurs C, Diray-Arce JInternational journal of molecular sciencesThe Implication of Sphingolipids in Viral Infections. Int J Mol Sci. 2023 Dec 09; 24(24).Int J Mol Sci2023-12-09T00:00:002023The Implication of Sphingolipids in Viral Infections.true1Research Fellow in PediatricsResearch Fellow in Pediatricstrue1Patricia K. Donahoe Professor of SurgeryPatricia K. Donahoe Professor of Surgerytrue1Professor of MedicineProfessor of MedicineRK210RachelKellyRachel Kelly, Ph.D.125226Kelly, RachelAssistant Professor of Medicine2Assistant Professor0Full Professor5Other FacultyTTH13TimothyHlaTimothy T Hla, Ph.D.153463Hla, TimothyPatricia K. Donahoe Professor of Surgery