2-Chloroadenosine

"2-Chloroadenosine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

2-Chloroadenosine. A metabolically stable analog of adenosine which acts as an adenosine receptor agonist. The compound has a potent effect on the peripheral and central nervous system.

Descriptor ID

D015762

MeSH Number(s)

D03.438.759.590.138.300

D13.570.583.138.300

D13.570.800.096.300

Concept/Terms

2-Chloroadenosine

Below are MeSH descriptors whose meaning is more general than "2-Chloroadenosine".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 2-Ring [D03.438]
Purines [D03.438.759]
Purine Nucleosides [D03.438.759.590]
Adenosine [D03.438.759.590.138]
2-Chloroadenosine [D03.438.759.590.138.300]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleosides [D13.570]
Purine Nucleosides [D13.570.583]
Adenosine [D13.570.583.138]
2-Chloroadenosine [D13.570.583.138.300]
Ribonucleosides [D13.570.800]
Adenosine [D13.570.800.096]
2-Chloroadenosine [D13.570.800.096.300]

Below are MeSH descriptors whose meaning is related to "2-Chloroadenosine".

Below are MeSH descriptors whose meaning is more specific than "2-Chloroadenosine".

2-Chloroadenosine
Cladribine

publications

Timeline | Most Recent

This graph shows the total number of publications written about "2-Chloroadenosine" by people in Harvard Catalyst Profiles by year, and whether "2-Chloroadenosine" was a major or minor topic of these publication.

Bar chart showing 5 publications over 4 distinct years, with a maximum of 2 publications in 2000

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1998	0	1	1
2000	1	1	2
2002	0	1	1

Below are the most recent publications written about "2-Chloroadenosine" by people in Profiles.

Integrative gene expression profiling reveals G6PD-mediated resistance to RNA-directed nucleoside analogues in B-cell neoplasms. PLoS One. 2012; 7(7):e41455.

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Gs protein-coupled adenosine receptor signaling and lytic function of activated NK cells. J Immunol. 2005 Oct 01; 175(7):4383-91.

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8-Chloro-cyclic AMP-induced growth inhibition and apoptosis is mediated by p38 mitogen-activated protein kinase activation in HL60 cells. Cancer Res. 2005 Jun 01; 65(11):4896-901.

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8-Cl-cAMP and its metabolite, 8-Cl-adenosine induce growth inhibition in mouse fibroblast DT cells through the same pathways: protein kinase C activation and cyclin B down-regulation. J Cell Physiol. 2004 Nov; 201(2):277-85.

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Facilitation at single synapses probed with optical quantal analysis. Nat Neurosci. 2002 Jul; 5(7):657-64.

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Modulation of audiogenic seizures by histamine and adenosine receptors in the inferior colliculus. Exp Neurol. 2000 May; 163(1):264-70.

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Altered regulation of potassium and calcium channels by GABA(B) and adenosine receptors in hippocampal neurons from mice lacking Galpha(o). J Neurophysiol. 2000 Feb; 83(2):1010-8.

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Neurotransmitter activation of inwardly rectifying potassium current in dissociated hippocampal CA3 neurons: interactions among multiple receptors. J Neurosci. 1998 Oct 15; 18(20):8153-62.

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Contributions of calcium-dependent and calcium-independent mechanisms to presynaptic inhibition at a cerebellar synapse. J Neurosci. 1996 Mar 01; 16(5):1623-33.

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A1 adenosine-receptor antagonists activate chloride efflux from cystic fibrosis cells. Proc Natl Acad Sci U S A. 1992 Jun 15; 89(12):5562-6.

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