Inositol 1,4,5-Trisphosphate Receptors
"Inositol 1,4,5-Trisphosphate Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Intracellular receptors that bind to INOSITOL 1,4,5-TRISPHOSPHATE and play an important role in its intracellular signaling. Inositol 1,4,5-trisphosphate receptors are calcium channels that release CALCIUM in response to increased levels of inositol 1,4,5-trisphosphate in the CYTOPLASM.
MeSH Number(s)
D12.776.157.530.400.150.760
D12.776.543.550.425.150.760
D12.776.543.585.400.150.760
D12.776.826.179
Concept/Terms
Inositol 1,4,5-Trisphosphate Receptors- Inositol 1,4,5-Trisphosphate Receptors
- Inositol 1,4,5-Triphosphate Receptors
- Receptor, Inositol-1,4,5-triphosphate
- IP3 Receptor
- Receptor, IP3
- 1,4,5-INTP Receptor
- INSP3 Receptor
- Receptor, INSP3
- Inositol Triphosphate Receptor
- Receptor, Inositol Triphosphate
- Triphosphate Receptor, Inositol
- Inositol-1,4,5-Triphosphate Receptor
Below are MeSH descriptors whose meaning is more general than "Inositol 1,4,5-Trisphosphate Receptors".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Calcium Channels [D12.776.157.530.400.150]
- Inositol 1,4,5-Trisphosphate Receptors [D12.776.157.530.400.150.760]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.425]
- Calcium Channels [D12.776.543.550.425.150]
- Inositol 1,4,5-Trisphosphate Receptors [D12.776.543.550.425.150.760]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Calcium Channels [D12.776.543.585.400.150]
- Inositol 1,4,5-Trisphosphate Receptors [D12.776.543.585.400.150.760]
- Receptors, Cytoplasmic and Nuclear [D12.776.826]
- Inositol 1,4,5-Trisphosphate Receptors [D12.776.826.179]
Below are MeSH descriptors whose meaning is more specific than "Inositol 1,4,5-Trisphosphate Receptors".
This graph shows the total number of publications written about "Inositol 1,4,5-Trisphosphate Receptors" by people in Harvard Catalyst Profiles by year, and whether "Inositol 1,4,5-Trisphosphate Receptors" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 4 | 4 |
1997 | 0 | 3 | 3 |
1998 | 0 | 2 | 2 |
1999 | 0 | 4 | 4 |
2001 | 0 | 3 | 3 |
2002 | 0 | 4 | 4 |
2003 | 0 | 3 | 3 |
2005 | 0 | 1 | 1 |
2006 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2008 | 3 | 3 | 6 |
2009 | 0 | 1 | 1 |
2010 | 2 | 2 | 4 |
2011 | 0 | 1 | 1 |
2012 | 0 | 1 | 1 |
2013 | 6 | 1 | 7 |
2014 | 1 | 2 | 3 |
2015 | 1 | 0 | 1 |
2016 | 0 | 1 | 1 |
2017 | 2 | 2 | 4 |
2018 | 0 | 1 | 1 |
2020 | 1 | 2 | 3 |
2021 | 1 | 0 | 1 |
Below are the most recent publications written about "Inositol 1,4,5-Trisphosphate Receptors" by people in Profiles.
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Potentially functional variants of HBEGF and ITPR3 in GnRH signaling pathway genes predict survival of non-small cell lung cancer patients. Transl Res. 2021 07; 233:92-103.
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Neutrophils interact with cholangiocytes to cause cholestatic changes in alcoholic hepatitis. Gut. 2021 02; 70(2):342-356.
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Modulation of calcium signaling depends on the oligosaccharide of GM1 in Neuro2a mouse neuroblastoma cells. Glycoconj J. 2020 12; 37(6):713-727.
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Epsin-mediated degradation of IP3R1 fuels atherosclerosis. Nat Commun. 2020 08 07; 11(1):3984.
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Caspr2 interacts with type 1 inositol 1,4,5-trisphosphate receptor in the developing cerebellum and regulates Purkinje cell morphology. J Biol Chem. 2020 09 04; 295(36):12716-12726.
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Trans-ethnic meta-analysis of genome-wide association studies identifies maternal ITPR1 as a novel locus influencing fetal growth during sensitive periods in pregnancy. PLoS Genet. 2020 05; 16(5):e1008747.
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Correlation Between Altered DNA Methylation of Intergenic Regions of ITPR3 and Development of Delayed Cerebral Ischemia in Patients with Subarachnoid Hemorrhage. World Neurosurg. 2019 Oct; 130:e449-e456.
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Non-canonical function of IRE1a determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics. Nat Cell Biol. 2019 06; 21(6):755-767.
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Chronotype and cellular circadian rhythms predict the clinical response to lithium maintenance treatment in patients with bipolar disorder. Neuropsychopharmacology. 2019 02; 44(3):620-628.
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Paclitaxel Reduces Axonal Bclw to Initiate IP3R1-Dependent Axon Degeneration. Neuron. 2017 Oct 11; 96(2):373-386.e6.