Mutant Chimeric Proteins

"Mutant Chimeric Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Proteins produced from GENES that have mutated by the fusing of protein coding regions of more than one gene. Such hybrid proteins are responsible for some instances of ANTIBIOTIC RESISTANCE and defective biological processes such as NEOPLASMS.

Descriptor ID

D050506

MeSH Number(s)

D12.776.602.500

Concept/Terms

Mutant Chimeric Proteins

Below are MeSH descriptors whose meaning is more general than "Mutant Chimeric Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Mutant Proteins [D12.776.602]
Mutant Chimeric Proteins [D12.776.602.500]

Below are MeSH descriptors whose meaning is related to "Mutant Chimeric Proteins".

Below are MeSH descriptors whose meaning is more specific than "Mutant Chimeric Proteins".

Mutant Chimeric Proteins
Oncogene Proteins, Fusion

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Mutant Chimeric Proteins" by people in Harvard Catalyst Profiles by year, and whether "Mutant Chimeric Proteins" was a major or minor topic of these publication.

Below are the most recent publications written about "Mutant Chimeric Proteins" by people in Profiles.

Structural and biochemical analyses indicate that a bacterial persulfide dioxygenase-rhodanese fusion protein functions in sulfur assimilation. J Biol Chem. 2017 08 25; 292(34):14026-14038.

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Comprehensive evaluation of fusion transcript detection algorithms and a meta-caller to combine top performing methods in paired-end RNA-seq data. Nucleic Acids Res. 2016 Mar 18; 44(5):e47.

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Stress-induced Aldosterone Hyper-Secretion in a Substantial Subset of Patients With Essential Hypertension. J Clin Endocrinol Metab. 2015 Aug; 100(8):2857-64.

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Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes. PLoS Genet. 2014 Aug; 10(8):e1004517.

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Formation of chimeric genes by copy-number variation as a mutational mechanism in schizophrenia. Am J Hum Genet. 2013 Oct 03; 93(4):697-710.

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Long-range transcriptome sequencing reveals cancer cell growth regulatory chimeric mRNA. Neoplasia. 2012 Nov; 14(11):1087-96.

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A novel group of Moraxella catarrhalis UspA proteins mediates cellular adhesion via CEACAMs and vitronectin. PLoS One. 2012; 7(9):e45452.

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Junction site analysis of chimeric CYP21A1P/CYP21A2 genes in 21-hydroxylase deficiency. Clin Chem. 2012 Feb; 58(2):421-30.

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A new presentation of the chimeric CYP11B1/CYP11B2 gene with low prevalence of primary aldosteronism and atypical gene segregation pattern. Hypertension. 2012 Jan; 59(1):85-91.

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Identification of a novel, recurrent HEY1-NCOA2 fusion in mesenchymal chondrosarcoma based on a genome-wide screen of exon-level expression data. Genes Chromosomes Cancer. 2012 Feb; 51(2):127-39.

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Nucleic Acids Res
J Biol Chem
Proc Natl Acad Sci U S A
Mol Biol Evol
PLoS One
PLoS Genet
Neoplasia
J Mol Evol
Clin Chem
Am J Hum Genet