Glutaryl-CoA Dehydrogenase

"Glutaryl-CoA Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A flavoprotein enzyme that is responsible for the catabolism of LYSINE; HYDROXYLYSINE; and TRYPTOPHAN. It catalyzes the oxidation of GLUTARYL-CoA to crotonoyl-CoA using FAD as a cofactor. Glutaric aciduria type I is an inborn error of metabolism due to the deficiency of glutaryl-CoA dehydrogenase.

Descriptor ID

D050770

MeSH Number(s)

D08.811.682.660.425

Concept/Terms

Glutaryl-CoA Dehydrogenase

Below are MeSH descriptors whose meaning is more general than "Glutaryl-CoA Dehydrogenase".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Oxidoreductases [D08.811.682]
Oxidoreductases Acting on CH-CH Group Donors [D08.811.682.660]
Glutaryl-CoA Dehydrogenase [D08.811.682.660.425]

Below are MeSH descriptors whose meaning is related to "Glutaryl-CoA Dehydrogenase".

Below are MeSH descriptors whose meaning is more specific than "Glutaryl-CoA Dehydrogenase".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Glutaryl-CoA Dehydrogenase" by people in Harvard Catalyst Profiles by year, and whether "Glutaryl-CoA Dehydrogenase" was a major or minor topic of these publication.

Bar chart showing 12 publications over 11 distinct years, with a maximum of 2 publications in 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	1	1
1995	0	1	1
2001	0	1	1
2004	0	1	1
2005	1	0	1
2010	1	0	1
2012	0	1	1
2016	1	0	1
2017	1	0	1
2018	0	1	1
2022	0	2	2

Below are the most recent publications written about "Glutaryl-CoA Dehydrogenase" by people in Profiles.

Detection of IEMs by Mass Spectrometry Techniques in High-Risk Children: A Pilot Study. Indian J Pediatr. 2022 09; 89(9):885-893.

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Standardizing genetic and metabolic consults for non-accidental trauma at a large pediatric academic center. Child Abuse Negl. 2022 03; 125:105480.

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Movement Disorders in Treatable Inborn Errors of Metabolism. Mov Disord. 2019 05; 34(5):598-613.

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Extrastriatal changes in patients with late-onset glutaric aciduria type I highlight the risk of long-term neurotoxicity. Orphanet J Rare Dis. 2017 04 24; 12(1):77.

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Immunolocalization of glutaryl-CoA dehydrogenase (GCDH) in adult and embryonic rat brain and peripheral tissues. Neuroscience. 2017 02 20; 343:355-363.

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Seizures, Dystonia, and Spasms in a 14-Year-Old Child. Clin Chem. 2016 08; 62(8):1159-60.

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Molecular determination of glutaric aciduria type I in individuals from southwest Iran. Arch Iran Med. 2014 Sep; 17(9):629-32.

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Ammonium accumulation and cell death in a rat 3D brain cell model of glutaric aciduria type I. PLoS One. 2013; 8(1):e53735.

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[Analysis of clinical features and GCDH gene mutations in four patients with glutaric academia type I]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2012 Dec; 29(6):642-7.

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Rhabdomyolysis, acute renal failure, and cardiac arrest secondary to status dystonicus in a child with glutaric aciduria type I. Mol Genet Metab. 2012 Aug; 106(4):488-90.

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Mol Genet Metab
Clin Chem
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
Orphanet J Rare Dis
Neuroscience
Neurology
Arch Iran Med
Pediatrics
Child Abuse Negl
Am J Med Genet