Dextropropoxyphene

"Dextropropoxyphene" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A narcotic analgesic structurally related to METHADONE. Only the dextro-isomer has an analgesic effect; the levo-isomer appears to exert an antitussive effect.

Descriptor ID

D011431

MeSH Number(s)

D02.241.081.751.725

Concept/Terms

Dextropropoxyphene

Propoxyphene Hydrochloride

Propoxyphene Hydrochloride, (R*,R*)-(+-)-Isomer

Propoxyphene Sulfate, (S-(R*,S*))-Isomer

Propoxyphene Hydrochloride, (R-(R*,S*))-Isomer

Propoxyphene Hydrochloride, (S-(R*,R*))-Isomer

Propoxyphene Maleate, (+)-Isomer

Propoxyphene Phosphate, (S-(R*,S*))-Isomer

Darvon

Propoxyphene Hydrochloride, (R-(R*,R*))-Isomer

Below are MeSH descriptors whose meaning is more general than "Dextropropoxyphene".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Carboxylic Acids [D02.241]
Acids, Acyclic [D02.241.081]
Propionates [D02.241.081.751]
Dextropropoxyphene [D02.241.081.751.725]

Below are MeSH descriptors whose meaning is related to "Dextropropoxyphene".

Below are MeSH descriptors whose meaning is more specific than "Dextropropoxyphene".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Dextropropoxyphene" by people in Harvard Catalyst Profiles by year, and whether "Dextropropoxyphene" was a major or minor topic of these publication.

Bar chart showing 7 publications over 7 distinct years, with a maximum of 1 publications in 1995 and 1997 and 2009 and 2010 and 2015 and 2016 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
1997	1	0	1
2009	1	0	1
2010	0	1	1
2015	0	1	1
2016	0	1	1
2020	1	0	1

Below are the most recent publications written about "Dextropropoxyphene" by people in Profiles.

Response to Propoxyphene Market Withdrawal: Analgesic Substitutes, Doses, and Adverse Events. Med Care. 2020 01; 58(1):4-12.

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Assessing the impact of prescribing directives on opioid prescribing practices among Veterans Health Administration providers. Pharmacoepidemiol Drug Saf. 2017 01; 26(1):40-46.

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Rates of opioid dispensing and overdose after introduction of abuse-deterrent extended-release oxycodone and withdrawal of propoxyphene. JAMA Intern Med. 2015 Jun; 175(6):978-87.

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The comparative safety of opioids for nonmalignant pain in older adults. Arch Intern Med. 2010 Dec 13; 170(22):1979-86.

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Twenty five years of poison center experience with propoxyphene overdoses the FDA could not find. Clin Toxicol (Phila). 2009 Nov; 47(9):905-6.

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[Who dies of morphine and dextropropoxyphene intoxication? Danish experiences from the period 1979-1992]. Ugeskr Laeger. 1997 Apr 14; 159(16):2370-4.

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Quantification of inflammation in the wrist with gadolinium-enhanced MR imaging and PET with 2-[F-18]-fluoro-2-deoxy-D-glucose. Radiology. 1995 Sep; 196(3):647-55.

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Examining product risk in context. Market withdrawal of zomepirac as a case study. JAMA. 1993 Oct 27; 270(16):1937-42.

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Consumption, overdose and death from analgesics during a period of over-the-counter availability of paracetamol in Denmark. J Intern Med. 1990 Jun; 227(6):423-8.

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Effect of government and commercial warnings on reducing prescription misuse: the case of propoxyphene. Am J Public Health. 1987 Dec; 77(12):1518-23.

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