"Vaccines, Conjugate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Semisynthetic vaccines consisting of polysaccharide antigens from microorganisms attached to protein carrier molecules. The carrier protein is recognized by macrophages and T-cells thus enhancing immunity. Conjugate vaccines induce antibody formation in people not responsive to polysaccharide alone, induce higher levels of antibody, and show a booster response on repeated injection.
MeSH Number(s)
D20.215.894.865.900
D23.050.865.900
Below are MeSH descriptors whose meaning is more general than "Vaccines, Conjugate".
Below are MeSH descriptors whose meaning is more specific than "Vaccines, Conjugate".
This graph shows the total number of publications written about "Vaccines, Conjugate" by people in Harvard Catalyst Profiles by year, and whether "Vaccines, Conjugate" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 3 | 3 |
1995 | 1 | 2 | 3 |
1996 | 2 | 4 | 6 |
1997 | 2 | 2 | 4 |
1998 | 1 | 2 | 3 |
1999 | 5 | 5 | 10 |
2000 | 0 | 2 | 2 |
2001 | 2 | 0 | 2 |
2002 | 1 | 4 | 5 |
2003 | 3 | 1 | 4 |
2004 | 2 | 3 | 5 |
2005 | 1 | 7 | 8 |
2006 | 1 | 1 | 2 |
2007 | 1 | 3 | 4 |
2008 | 2 | 2 | 4 |
2009 | 2 | 3 | 5 |
2010 | 1 | 4 | 5 |
2011 | 1 | 4 | 5 |
2012 | 3 | 5 | 8 |
2013 | 1 | 5 | 6 |
2014 | 2 | 4 | 6 |
2015 | 5 | 8 | 13 |
2016 | 3 | 2 | 5 |
2017 | 3 | 7 | 10 |
2018 | 5 | 7 | 12 |
2019 | 1 | 8 | 9 |
2020 | 2 | 11 | 13 |
2021 | 1 | 6 | 7 |
2022 | 0 | 13 | 13 |
2023 | 0 | 5 | 5 |
2024 | 0 | 5 | 5 |
Below are the most recent publications written about "Vaccines, Conjugate" by people in Profiles.
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Safety, tolerability and immunogenicity of a novel 24-valent pneumococcal vaccine in toddlers: A phase 1 randomized controlled trial. Vaccine. 2024 Apr 11; 42(10):2560-2571.
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Immunization with a whole cell vaccine reduces pneumococcal nasopharyngeal density and shedding, and middle ear infection in mice. Vaccine. 2024 Mar 07; 42(7):1714-1722.
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Antimicrobial resistance of Streptococcus pneumoniae from invasive pneumococcal diseases in Latin American countries: a systematic review and meta-analysis. Front Public Health. 2024; 12:1337276.
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Multiple antigen presenting system (MAPS): state of the art and potential applications. Expert Rev Vaccines. 2024 Jan-Dec; 23(1):196-204.
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Invasive Pneumococcal Disease After 2 Decades of Pneumococcal Conjugate Vaccine Use. Pediatrics. 2024 Jan 01; 153(1).
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Vaccination of Rabbits with a Cholera Conjugate Vaccine Comprising O-Specific Polysaccharide and a Recombinant Fragment of Tetanus Toxin Heavy Chain Induces Protective Immune Responses against Vibrio cholerae O1. Am J Trop Med Hyg. 2023 11 01; 109(5):1122-1128.
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Health Care Provider Knowledge and Attitudes Regarding Adult Pneumococcal Conjugate Vaccine Recommendations - United States, September 28-October 10, 2022. MMWR Morb Mortal Wkly Rep. 2023 Sep 08; 72(36):979-984.
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Immunogenicity of quadrivalent meningococcal conjugate vaccine in frequent platelet donors. Blood. 2023 07 13; 142(2):202-209.
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Using LASSO Regression to Estimate the Population-Level Impact of Pneumococcal Conjugate Vaccines. Am J Epidemiol. 2023 07 07; 192(7):1166-1180.
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Development of Shigella conjugate vaccines targeting Shigella flexneri 2a and S. flexneri 3a using a simple platform-approach conjugation by squaric acid chemistry. Vaccine. 2023 07 31; 41(34):4967-4977.