"VDJ Exons" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Exons that are created in vivo during LYMPHOCYTE maturation from the V, D, and J gene segments of immunoglobulin superfamily genes (e.g., the IMMUNOGLOBULIN HEAVY CHAIN GENES, or the T-CELL RECEPTOR BETA GENES or T-CELL RECEPTOR GAMMA GENES ) by the VDJ RECOMBINASE system.
MeSH Number(s)
G05.360.340.024.340.137.232.920
G05.360.340.024.340.335.655
Concept/Terms
VDJ Exons- VDJ Exons
- Exon, VDJ
- Exons, VDJ
- V(D)J Exons
- VDJ Exon
Below are MeSH descriptors whose meaning is more general than "VDJ Exons".
Below are MeSH descriptors whose meaning is more specific than "VDJ Exons".
This graph shows the total number of publications written about "VDJ Exons" by people in Harvard Catalyst Profiles by year, and whether "VDJ Exons" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 2 | 0 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 1 | 2 |
Below are the most recent publications written about "VDJ Exons" by people in Profiles.
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Chromosomal translocation t(11;14) and p53 deletion induced by the CRISPR/Cas9 system in normal B cell-derived iPS cells. Sci Rep. 2021 03 04; 11(1):5216.
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Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching. Nature. 2015 Sep 03; 525(7567):134-139.
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CTCF-binding elements 1 and 2 in the Igh intergenic control region cooperatively regulate V(D)J recombination. Proc Natl Acad Sci U S A. 2015 Feb 10; 112(6):1815-20.
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Integrating B cell lineage information into statistical tests for detecting selection in Ig sequences. J Immunol. 2014 Feb 01; 192(3):867-74.
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Flexible ordering of antibody class switch and V(D)J joining during B-cell ontogeny. Genes Dev. 2013 Nov 15; 27(22):2439-44.
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CTCF-binding elements mediate control of V(D)J recombination. Nature. 2011 Sep 11; 477(7365):424-30.
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Analysis of mice lacking DNaseI hypersensitive sites at the 5' end of the IgH locus. PLoS One. 2010 Nov 15; 5(11):e13992.
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DH and JH usage in murine fetal liver mirrors that of human fetal liver. Immunogenetics. 2010 Oct; 62(10):653-66.
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Leaky severe combined immunodeficiency and aberrant DNA rearrangements due to a hypomorphic RAG1 mutation. Blood. 2009 Mar 26; 113(13):2965-75.
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Functional overlap in the cis-acting regulation of the V(D)J recombination at the TCRbeta locus. Mol Immunol. 2009 Jan; 46(3):321-6.