Polynucleotide 5'-Hydroxyl-Kinase

"Polynucleotide 5'-Hydroxyl-Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An enzyme that catalyzes the transfer of a phosphate group to the 5'-terminal hydroxyl groups of DNA and RNA. EC 2.7.1.78.

Descriptor ID

D011116

MeSH Number(s)

D08.811.074.875

D08.811.913.696.620.680

Concept/Terms

Polynucleotide 5'-Hydroxyl-Kinase

Below are MeSH descriptors whose meaning is more general than "Polynucleotide 5'-Hydroxyl-Kinase".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
DNA Repair Enzymes [D08.811.074]
Polynucleotide 5'-Hydroxyl-Kinase [D08.811.074.875]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Polynucleotide 5'-Hydroxyl-Kinase [D08.811.913.696.620.680]

Below are MeSH descriptors whose meaning is related to "Polynucleotide 5'-Hydroxyl-Kinase".

Below are MeSH descriptors whose meaning is more specific than "Polynucleotide 5'-Hydroxyl-Kinase".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Polynucleotide 5'-Hydroxyl-Kinase" by people in Harvard Catalyst Profiles by year, and whether "Polynucleotide 5'-Hydroxyl-Kinase" was a major or minor topic of these publication.

Bar chart showing 4 publications over 4 distinct years, with a maximum of 1 publications in 2001 and 2007 and 2010 and 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	0	1	1
2007	1	0	1
2010	0	1	1
2013	1	0	1

Below are the most recent publications written about "Polynucleotide 5'-Hydroxyl-Kinase" by people in Profiles.

Detection of circulating extracellular mRNAs by modified small-RNA-sequencing analysis. JCI Insight. 2019 04 11; 5.

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GRP78/Dna K Is a Target for Nexavar/Stivarga/Votrient in the Treatment of Human Malignancies, Viral Infections and Bacterial Diseases. J Cell Physiol. 2015 Oct; 230(10):2552-78.

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Label-free luminescence switch-on detection of T4 polynucleotide kinase activity using a G-quadruplex-selective probe. Chem Commun (Camb). 2014 May 25; 50(40):5313-5.

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Direct observation of enzymes replicating DNA using a single-molecule DNA stretching assay. J Vis Exp. 2010 Mar 23; (37).

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Real-time monitoring of the activity and kinetics of T4 polynucleotide kinase by a singly labeled DNA-hairpin smart probe coupled with lambda exonuclease cleavage. Anal Chem. 2009 Feb 15; 81(4):1383-8.

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Single-molecule observation of prokaryotic DNA replication. Methods Mol Biol. 2009; 521:397-410.

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Sequencing by Cyclic Ligation and Cleavage (CycLiC) directly on a microarray captured template. Nucleic Acids Res. 2009 Jan; 37(1):e5.

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XRCC1 stimulates polynucleotide kinase by enhancing its damage discrimination and displacement from DNA repair intermediates. J Biol Chem. 2007 Sep 21; 282(38):28004-13.

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Correction of DNA protein kinase deficiency by spliceosome-mediated RNA trans-splicing and sleeping beauty transposon delivery. Mol Ther. 2007 Jul; 15(7):1273-9.

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Mutation screening and association study of the beta-adrenergic receptor kinase 2 gene in schizophrenia families. Psychiatry Res. 2004 Feb 15; 125(2):95-104.

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