Receptor, Serotonin, 5-HT1D
"Receptor, Serotonin, 5-HT1D" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serotonin receptor subtype that is localized to the CAUDATE NUCLEUS; PUTAMEN; the NUCLEUS ACCUMBENS; the HIPPOCAMPUS, and the RAPHE NUCLEI. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1B RECEPTOR, but is expressed at low levels. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigrane effect.
MeSH Number(s)
D12.776.543.750.070.800.100.200
D12.776.543.750.100.800.100.200
D12.776.543.750.720.300.800.100.200
D12.776.543.750.720.670.100.750
Concept/Terms
Receptor, Serotonin, 5-HT1D- Receptor, Serotonin, 5-HT1D
- 5-HT1D Receptor
- 5 HT1D Receptor
- Receptor, 5-HT1D
- 5-Hydroxytryptamine1D Receptor
- 5 Hydroxytryptamine1D Receptor
- Receptor, 5-Hydroxytryptamine1D
- Serotonin 1D Receptor
- Serotonin 1D Receptors
- Receptors, Serotonin 1D
- 5-HT(1D) Receptor
- Receptor, Serotonin 1D
5-HT(1Dalpha) Receptor- 5-HT(1Dalpha) Receptor
- Serotonin 1Dalpha Receptors
- Serotonin 1D Alpha Receptor
- Serotonin 1Dalpha Receptor
- 5-HT1Dalpha Receptor
- Receptor, Serotonin 1Dalpha
Below are MeSH descriptors whose meaning is more general than "Receptor, Serotonin, 5-HT1D".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.070]
- Receptors, Serotonin [D12.776.543.750.070.800]
- Receptors, Serotonin, 5-HT1 [D12.776.543.750.070.800.100]
- Receptor, Serotonin, 5-HT1D [D12.776.543.750.070.800.100.200]
- Receptors, G-Protein-Coupled [D12.776.543.750.100]
- Receptors, Serotonin [D12.776.543.750.100.800]
- Receptors, Serotonin, 5-HT1 [D12.776.543.750.100.800.100]
- Receptor, Serotonin, 5-HT1D [D12.776.543.750.100.800.100.200]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Biogenic Amine [D12.776.543.750.720.300]
- Receptors, Serotonin [D12.776.543.750.720.300.800]
- Receptors, Serotonin, 5-HT1 [D12.776.543.750.720.300.800.100]
- Receptor, Serotonin, 5-HT1D [D12.776.543.750.720.300.800.100.200]
- Receptors, Presynaptic [D12.776.543.750.720.670]
- Autoreceptors [D12.776.543.750.720.670.100]
- Receptor, Serotonin, 5-HT1D [D12.776.543.750.720.670.100.750]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Serotonin, 5-HT1D".
This graph shows the total number of publications written about "Receptor, Serotonin, 5-HT1D" by people in Harvard Catalyst Profiles by year, and whether "Receptor, Serotonin, 5-HT1D" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
Below are the most recent publications written about "Receptor, Serotonin, 5-HT1D" by people in Profiles.
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Protective effects of sumatriptan on ischaemia/reperfusion injury following torsion/detorsion in ipsilateral and contralateral testes of rat. Andrologia. 2019 Oct; 51(9):e13358.
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Pharmacological evidence of involvement of nitric oxide pathway in anti-pruritic effects of sumatriptan in chloroquine-induced scratching in mice. Fundam Clin Pharmacol. 2018 Feb; 32(1):69-76.
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Transcriptional expression of serotonergic regulators in laser-captured microdissected dorsal raphe neurons of subjects with major depressive disorder: sex-specific differences. J Neurochem. 2010 Jan; 112(2):397-409.
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Serotonin type 1D receptors (5HTR) are differentially distributed in nerve fibres innervating craniofacial tissues. Cephalalgia. 2008 Sep; 28(9):933-44.
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G protein beta3 polymorphism and triptan response in cluster headache. Clin Pharmacol Ther. 2007 Oct; 82(4):396-401.
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The serotonin 5-HT1D receptor gene and attention-deficit hyperactivity disorder in Chinese Han subjects. Am J Med Genet B Neuropsychiatr Genet. 2006 Dec 05; 141B(8):874-6.
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Association analysis of monoamine genes with measures of depression and anxiety in a selected community sample of siblings. Am J Med Genet B Neuropsychiatr Genet. 2005 May 05; 135B(1):33-7.
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5-Hydroxytryptamine(1B/1D) and 5-hydroxytryptamine1F receptors inhibit capsaicin-induced c-fos immunoreactivity within mouse trigeminal nucleus caudalis. Cephalalgia. 2002 Jun; 22(5):384-94.
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Safety and efficacy of PNU-142633, a selective 5-HT1D agonist, in patients with acute migraine. Cephalalgia. 2001 Sep; 21(7):727-32.
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Effects of PNU-109,291, a selective 5-HT1D receptor agonist, on electrically induced dural plasma extravasation and capsaicin-evoked c-fos immunoreactivity within trigeminal nucleus caudalis. Neuropharmacology. 1999 Jul; 38(7):1043-53.