Ribosomal Protein S6

"Ribosomal Protein S6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A ribosomal protein that may play a role in controlling cell growth and proliferation. It is a major substrate of RIBOSOMAL PROTEIN S6 KINASES and plays a role in regulating the translation (TRANSLATION, GENETIC) of RNAs that contain an RNA 5' TERMINAL OLIGOPYRIMIDINE SEQUENCE.

Descriptor ID

D038601

MeSH Number(s)

D12.776.835.931

Concept/Terms

Ribosomal Protein S6

Below are MeSH descriptors whose meaning is more general than "Ribosomal Protein S6".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Ribosomal Proteins [D12.776.835]
Ribosomal Protein S6 [D12.776.835.931]

Below are MeSH descriptors whose meaning is related to "Ribosomal Protein S6".

Below are MeSH descriptors whose meaning is more specific than "Ribosomal Protein S6".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Ribosomal Protein S6" by people in Harvard Catalyst Profiles by year, and whether "Ribosomal Protein S6" was a major or minor topic of these publication.

Bar chart showing 37 publications over 18 distinct years, with a maximum of 5 publications in 2014 and 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	0	1	1
2002	0	1	1
2003	0	3	3
2004	1	2	3
2006	1	0	1
2007	0	2	2
2008	0	1	1
2009	0	2	2
2010	2	0	2
2011	1	0	1
2012	0	2	2
2013	1	2	3
2014	0	5	5
2015	3	2	5
2017	1	1	2
2018	0	1	1
2020	0	1	1
2022	1	0	1

Below are the most recent publications written about "Ribosomal Protein S6" by people in Profiles.

Midkine Promotes Metastasis and Therapeutic Resistance via mTOR/RPS6 in Uveal Melanoma. Mol Cancer Res. 2022 08 05; 20(8):1320-1336.

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Chd8 haploinsufficiency impairs early brain development and protein homeostasis later in life. Mol Autism. 2020 10 05; 11(1):74.

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PKCe contributes to lipid-induced insulin resistance through cross talk with p70S6K and through previously unknown regulators of insulin signaling. Proc Natl Acad Sci U S A. 2018 09 18; 115(38):E8996-E9005.

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Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts. Proc Natl Acad Sci U S A. 2018 04 17; 115(16):4206-4211.

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Clinical Characteristics of Connective Tissue Nevi in Tuberous Sclerosis Complex With Special Emphasis on Shagreen Patches. JAMA Dermatol. 2017 07 01; 153(7):660-665.

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mTOR, VEGF, PDGFR, and c-kit signaling pathway activation in Kaposi sarcoma. Hum Pathol. 2017 07; 65:157-165.

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Clinical, Molecular, and Immune Analysis of Dabrafenib-Trametinib Combination Treatment for BRAF Inhibitor-Refractory Metastatic Melanoma: A Phase 2 Clinical Trial. JAMA Oncol. 2016 Aug 01; 2(8):1056-64.

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Mammalian ataxin-2 modulates translation control at the pre-initiation complex via PI3K/mTOR and is induced by starvation. Biochim Biophys Acta. 2016 09; 1862(9):1558-69.

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Hypophosphorylation of ribosomal protein S6 is a molecular mechanism underlying ischemic tolerance induced by either hibernation or preconditioning. J Neurochem. 2015 Dec; 135(5):943-57.

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Improvement of tuberous sclerosis complex (TSC) skin tumors during long-term treatment with oral sirolimus. J Am Acad Dermatol. 2015 Nov; 73(5):802-8.

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