Chromosomes, Artificial, Human
"Chromosomes, Artificial, Human" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
DNA constructs that are composed of, at least, all elements, such as a REPLICATION ORIGIN; TELOMERE; and CENTROMERE, required for successful replication, propagation to and maintainance in progeny human cells. In addition, they are constructed to carry other sequences for analysis or gene transfer.
MeSH Number(s)
A11.284.187.178.190.117
A11.284.187.520.190.117
A11.284.187.520.300.117
G05.360.162.178.190.117
G05.360.162.520.190.117
G05.360.162.520.300.117
G05.360.337.249.190.117
Concept/Terms
Chromosomes, Artificial, Human- Chromosomes, Artificial, Human
- Human Artificial Chromosomes
- HACs (Chromosomes)
- HAC (Chromosome)
- Chromosomes, Human Artificial
- Artificial Chromosomes, Human
- Artificial Chromosome, Human
- Chromosome, Human Artificial
- Human Artificial Chromosome
Below are MeSH descriptors whose meaning is more general than "Chromosomes, Artificial, Human".
- Anatomy [A]
- Cells [A11]
- Cellular Structures [A11.284]
- Chromosomes [A11.284.187]
- Chromosomes, Artificial [A11.284.187.178]
- Chromosomes, Artificial, Mammalian [A11.284.187.178.190]
- Chromosomes, Artificial, Human [A11.284.187.178.190.117]
- Chromosomes, Mammalian [A11.284.187.520]
- Chromosomes, Artificial, Mammalian [A11.284.187.520.190]
- Chromosomes, Artificial, Human [A11.284.187.520.190.117]
- Chromosomes, Human [A11.284.187.520.300]
- Chromosomes, Artificial, Human [A11.284.187.520.300.117]
- Biological Sciences [G]
- Genetic Phenomena [G05]
- Genetic Structures [G05.360]
- Chromosomes [G05.360.162]
- Chromosomes, Artificial [G05.360.162.178]
- Chromosomes, Artificial, Mammalian [G05.360.162.178.190]
- Chromosomes, Artificial, Human [G05.360.162.178.190.117]
- Chromosomes, Mammalian [G05.360.162.520]
- Chromosomes, Artificial, Mammalian [G05.360.162.520.190]
- Chromosomes, Artificial, Human [G05.360.162.520.190.117]
- Chromosomes, Human [G05.360.162.520.300]
- Chromosomes, Artificial, Human [G05.360.162.520.300.117]
- Genetic Vectors [G05.360.337]
- Chromosomes, Artificial [G05.360.337.249]
- Chromosomes, Artificial, Mammalian [G05.360.337.249.190]
- Chromosomes, Artificial, Human [G05.360.337.249.190.117]
Below are MeSH descriptors whose meaning is more specific than "Chromosomes, Artificial, Human".
This graph shows the total number of publications written about "Chromosomes, Artificial, Human" by people in Harvard Catalyst Profiles by year, and whether "Chromosomes, Artificial, Human" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
2005 | 1 | 0 | 1 |
2010 | 1 | 0 | 1 |
2012 | 1 | 1 | 2 |
2015 | 0 | 1 | 1 |
2020 | 1 | 0 | 1 |
Below are the most recent publications written about "Chromosomes, Artificial, Human" by people in Profiles.
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H3K9me3 maintenance on a human artificial chromosome is required for segregation but not centromere epigenetic memory. J Cell Sci. 2020 07 24; 133(14).
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Epigenetic engineering shows that a human centromere resists silencing mediated by H3K27me3/K9me3. Mol Biol Cell. 2016 Jan 01; 27(1):177-96.
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HACking the centromere chromatin code: insights from human artificial chromosomes. Chromosome Res. 2012 Jul; 20(5):505-19.
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Epigenetic engineering: histone H3K9 acetylation is compatible with kinetochore structure and function. J Cell Sci. 2012 Jan 15; 125(Pt 2):411-21.
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Epigenetic engineering shows H3K4me2 is required for HJURP targeting and CENP-A assembly on a synthetic human kinetochore. EMBO J. 2011 Jan 19; 30(2):328-40.
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Assembly of additional heterochromatin distinct from centromere-kinetochore chromatin is required for de novo formation of human artificial chromosome. J Cell Sci. 2005 Dec 15; 118(Pt 24):5885-98.