Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Heavy Chain Disease

"Heavy Chain Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
Definition  |  Details  |  More General Concepts  |  Related Concepts  |  More Specific Concepts
A disorder of immunoglobulin synthesis in which large quantities of abnormal heavy chains are excreted in the urine. The amino acid sequences of the N-(amino-) terminal regions of these chains are normal, but they have a deletion extending from part of the variable domain through the first domain of the constant region, so that they cannot form cross-links to the light chains. The defect arises through faulty coupling of the variable (V) and constant (C) region genes.


publications
Timeline   |   Most Recent
This graph shows the total number of publications written about "Heavy Chain Disease" by people in Harvard Catalyst Profiles by year, and whether "Heavy Chain Disease" was a major or minor topic of these publication.
Bar chart showing 8 publications over 5 distinct years, with a maximum of 4 publications in 2014
To see the data from this visualization as text, click here.
Related Networks
People
Explore
_
Similar Concepts
_
Top Journals 
_
© 2024 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.