"omega-Agatoxin IVA" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A neuropeptide toxin from the venom of the funnel web spider, Agelenopsis aperta. It inhibits CALCIUM CHANNELS, P-TYPE by altering the voltage-dependent gating so that very large depolarizations are needed for channel opening. It also inhibits CALCIUM CHANNELS, Q-TYPE.
MeSH Number(s)
D12.644.400.562
D12.776.092.249.500
D20.888.065.870.324.500
D23.946.833.065.870.324.500
Concept/Terms
omega-Agatoxin IVA- omega-Agatoxin IVA
- IVA, omega-Agatoxin
- omega Agatoxin IVA
- omega-Aga-IVA
- omega Aga IVA
Below are MeSH descriptors whose meaning is more general than "omega-Agatoxin IVA".
Below are MeSH descriptors whose meaning is more specific than "omega-Agatoxin IVA".
This graph shows the total number of publications written about "omega-Agatoxin IVA" by people in Harvard Catalyst Profiles by year, and whether "omega-Agatoxin IVA" was a major or minor topic of these publication.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 2 | 2 |
| 1997 | 0 | 2 | 2 |
| 1999 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
Below are the most recent publications written about "omega-Agatoxin IVA" by people in Profiles.
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Interdependent Conductances Drive Infraslow Intrinsic Rhythmogenesis in a Subset of Accessory Olfactory Bulb Projection Neurons. J Neurosci. 2016 Mar 16; 36(11):3127-44.
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Presynaptic calcium influx controls neurotransmitter release in part by regulating the effective size of the readily releasable pool. J Neurosci. 2013 Mar 13; 33(11):4625-33.
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Calcium microdomains near R-type calcium channels control the induction of presynaptic long-term potentiation at parallel fiber to purkinje cell synapses. J Neurosci. 2011 Apr 06; 31(14):5235-43.
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Compensatory contribution of Cav2.3 channels to acetylcholine release at the neuromuscular junction of tottering mice. J Neurophysiol. 2006 Apr; 95(4):2698-704.
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Interactions among toxins that inhibit N-type and P-type calcium channels. J Gen Physiol. 2002 Apr; 119(4):313-28.
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Cation channel control of neurite morphology. Brain Res Dev Brain Res. 1999 Mar 12; 113(1-2):67-73.
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Voltage-dependent inhibition of N- and P-type calcium channels by the peptide toxin omega-grammotoxin-SIA. Mol Pharmacol. 1997 Dec; 52(6):1095-104.
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Alteration of P-type calcium channel gating by the spider toxin omega-Aga-IVA. Biophys J. 1997 May; 72(5):2117-28.
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Calcium control of transmitter release at a cerebellar synapse. Neuron. 1995 Sep; 15(3):675-88.
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Differential blockade of voltage-sensitive calcium channels at the mouse neuromuscular junction by novel omega-conopeptides and omega-agatoxin-IVA. J Pharmacol Exp Ther. 1995 Apr; 273(1):248-56.