Gonadal Dysgenesis, Mixed
"Gonadal Dysgenesis, Mixed" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A type of defective gonadal development in patients with a wide spectrum of chromosomal mosaic variants. Their karyotypes are of partial sex chromosome monosomy resulting from an absence or an abnormal second sex chromosome (X or Y). Karyotypes include 45,X/46,XX; 45,X/46,XX/47,XXX; 46,XXp-; 45,X/46,XY; 45,X/47,XYY; 46,XYpi; etc. The spectrum of phenotypes may range from phenotypic female to phenotypic male including variations in gonads and internal and external genitalia, depending on the ratio in each gonad of 45,X primordial germ cells to those with normal 46,XX or 46,XY constitution.
MeSH Number(s)
C12.706.316.309.391
C12.706.316.795.249
C13.351.875.253.309.391
C13.351.875.253.795.249
C16.131.260.830.835.249
C16.131.939.316.309.391
C16.131.939.316.795.249
C16.320.180.830.835.249
C19.391.119.309.391
C19.391.119.795.249
Below are MeSH descriptors whose meaning is more general than "Gonadal Dysgenesis, Mixed".
- Diseases [C]
- Male Urogenital Diseases [C12]
- Urogenital Abnormalities [C12.706]
- Disorders of Sex Development [C12.706.316]
- Gonadal Dysgenesis [C12.706.316.309]
- Gonadal Dysgenesis, Mixed [C12.706.316.309.391]
- Sex Chromosome Disorders of Sex Development [C12.706.316.795]
- Gonadal Dysgenesis, Mixed [C12.706.316.795.249]
- Female Urogenital Diseases and Pregnancy Complications [C13]
- Female Urogenital Diseases [C13.351]
- Urogenital Abnormalities [C13.351.875]
- Disorders of Sex Development [C13.351.875.253]
- Gonadal Dysgenesis [C13.351.875.253.309]
- Gonadal Dysgenesis, Mixed [C13.351.875.253.309.391]
- Sex Chromosome Disorders of Sex Development [C13.351.875.253.795]
- Gonadal Dysgenesis, Mixed [C13.351.875.253.795.249]
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Congenital Abnormalities [C16.131]
- Chromosome Disorders [C16.131.260]
- Sex Chromosome Disorders [C16.131.260.830]
- Sex Chromosome Disorders of Sex Development [C16.131.260.830.835]
- Gonadal Dysgenesis, Mixed [C16.131.260.830.835.249]
- Urogenital Abnormalities [C16.131.939]
- Disorders of Sex Development [C16.131.939.316]
- Gonadal Dysgenesis [C16.131.939.316.309]
- Gonadal Dysgenesis, Mixed [C16.131.939.316.309.391]
- Sex Chromosome Disorders of Sex Development [C16.131.939.316.795]
- Gonadal Dysgenesis, Mixed [C16.131.939.316.795.249]
- Genetic Diseases, Inborn [C16.320]
- Chromosome Disorders [C16.320.180]
- Sex Chromosome Disorders [C16.320.180.830]
- Sex Chromosome Disorders of Sex Development [C16.320.180.830.835]
- Gonadal Dysgenesis, Mixed [C16.320.180.830.835.249]
- Endocrine System Diseases [C19]
- Gonadal Disorders [C19.391]
- Disorders of Sex Development [C19.391.119]
- Gonadal Dysgenesis [C19.391.119.309]
- Gonadal Dysgenesis, Mixed [C19.391.119.309.391]
- Sex Chromosome Disorders of Sex Development [C19.391.119.795]
- Gonadal Dysgenesis, Mixed [C19.391.119.795.249]
Below are MeSH descriptors whose meaning is more specific than "Gonadal Dysgenesis, Mixed".
This graph shows the total number of publications written about "Gonadal Dysgenesis, Mixed" by people in Harvard Catalyst Profiles by year, and whether "Gonadal Dysgenesis, Mixed" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
1994 | 1 | 0 | 1 |
1995 | 1 | 0 | 1 |
2008 | 1 | 0 | 1 |
Below are the most recent publications written about "Gonadal Dysgenesis, Mixed" by people in Profiles.
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Short stature in a phenotypic male caused by mixed gonadal dysgenesis. Nat Clin Pract Endocrinol Metab. 2008 Sep; 4(9):524-8.
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Surgical approach to intersex problems. Semin Pediatr Surg. 1998 Feb; 7(1):8-18.
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Mixed gonadal dysgenesis and dysgenetic male pseudohermaphroditism. J Urol. 1995 Apr; 153(4):1267-73.
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Ambiguous genitalia. Curr Ther Endocrinol Metab. 1994; 5:242-9.
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Molecular analysis of 46,XY females and regional assignment of a new Y-chromosome-specific probe. Hum Genet. 1989 Aug; 83(1):88-92.
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Neoseminal vesicle created from retained mullerian duct to preserve the vas in male infants. J Pediatr Surg. 1988 Mar; 23(3):272-4.
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Perineal reconstruction in ambiguous genitalia infants raised as females. Ann Surg. 1984 Sep; 200(3):363-71.
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Dysgenesis of testicular and streak gonads in the syndrome of mixed gonadal dysgenesis: perspective derived from a clinicopathologic analysis of twenty-one cases. Hum Pathol. 1982 Aug; 13(8):700-16.
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Symposium on Adolescent Gynecology and Endocrinology. Part I: Physiology of sexual maturation and primary amenorrhea. Primary amenorrhea. West J Med. 1979 Nov; 131(5):411-6.