Sodium Chloride Symporters

"Sodium Chloride Symporters" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A subclass of symporters found in KIDNEY TUBULES, DISTAL that are the major pathway for salt resorption. Inhibition of these symporters by BENZOTHIADIAZINES is the basis of action of some DIURETICS.

Descriptor ID

D049992

MeSH Number(s)

D12.776.157.530.450.625.374

Concept/Terms

Sodium Chloride Symporters

Below are MeSH descriptors whose meaning is more general than "Sodium Chloride Symporters".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Membrane Transport Proteins [D12.776.157.530]
Ion Pumps [D12.776.157.530.450]
Symporters [D12.776.157.530.450.625]
Sodium Chloride Symporters [D12.776.157.530.450.625.374]

Below are MeSH descriptors whose meaning is related to "Sodium Chloride Symporters".

Below are MeSH descriptors whose meaning is more specific than "Sodium Chloride Symporters".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Sodium Chloride Symporters" by people in Harvard Catalyst Profiles by year, and whether "Sodium Chloride Symporters" was a major or minor topic of these publication.

Bar chart showing 9 publications over 8 distinct years, with a maximum of 2 publications in 2003

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
2002	0	1	1
2003	0	2	2
2005	0	1	1
2006	0	1	1
2009	1	0	1
2015	1	0	1
2019	0	1	1

Below are the most recent publications written about "Sodium Chloride Symporters" by people in Profiles.

Mannitol decreases neocortical epileptiform activity during early brain development via cotransport of chloride and water. Neurobiol Dis. 2019 05; 125:163-175.

View in: PubMed
Impaired natriuretic response to high-NaCl diet plus aldosterone infusion in mice overexpressing human CD39, an ectonucleotidase (NTPDase1). Am J Physiol Renal Physiol. 2015 Jun 15; 308(12):F1398-408.

View in: PubMed
A primary culture of distal convoluted tubules expressing functional thiazide-sensitive NaCl transport. Am J Physiol Renal Physiol. 2012 Sep 15; 303(6):F886-92.

View in: PubMed
Acute insulin stimulation induces phosphorylation of the Na-Cl cotransporter in cultured distal mpkDCT cells and mouse kidney. PLoS One. 2011; 6(8):e24277.

View in: PubMed
Epigenetic modulation of the renal ß-adrenergic-WNK4 pathway in salt-sensitive hypertension. Nat Med. 2011 May; 17(5):573-80.

View in: PubMed
Angiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathway. Proc Natl Acad Sci U S A. 2009 Mar 17; 106(11):4384-9.

View in: PubMed
Wnk4 controls blood pressure and potassium homeostasis via regulation of mass and activity of the distal convoluted tubule. Nat Genet. 2006 Oct; 38(10):1124-32.

View in: PubMed
WNK3, a kinase related to genes mutated in hereditary hypertension with hyperkalaemia, regulates the K+ channel ROMK1 (Kir1.1). J Physiol. 2006 Mar 01; 571(Pt 2):275-86.

View in: PubMed
WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion. Nat Genet. 2003 Dec; 35(4):372-6.

View in: PubMed
Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4. Proc Natl Acad Sci U S A. 2003 Jan 21; 100(2):680-4.

View in: PubMed

Related Networks

People

Explore

Similar Concepts

Top Journals

Am J Physiol Renal Physiol
Proc Natl Acad Sci U S A
PLoS One
Nat Genet
Nat Med
J Physiol
J Am Soc Nephrol
Biochem Biophys Res Commun
Annu Rev Physiol
Am J Physiol