Receptors, Interleukin-7

"Receptors, Interleukin-7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Cell surface receptors that are specific for INTERLEUKIN-7. They are present on T-LYMPHOCYTES and B-LYMPHOCYTE precursors. The receptors are heterodimeric proteins consisting of the INTERLEUKIN-5 RECEPTOR ALPHA SUBUNIT and the CYTOKINE RECEPTOR COMMON BETA SUBUNIT.

Descriptor ID

D020395

MeSH Number(s)

D12.776.543.750.705.852.420.420

D23.050.301.264.035.715

D23.101.100.110.715

Concept/Terms

Receptors, Interleukin-7

Below are MeSH descriptors whose meaning is more general than "Receptors, Interleukin-7".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Cytokine [D12.776.543.750.705.852]
Receptors, Interleukin [D12.776.543.750.705.852.420]
Receptors, Interleukin-7 [D12.776.543.750.705.852.420.420]
Biological Factors [D23]
Antigens [D23.050]
Antigens, Surface [D23.050.301]
Antigens, Differentiation [D23.050.301.264]
Antigens, CD [D23.050.301.264.035]
Receptors, Interleukin-7 [D23.050.301.264.035.715]
Biological Markers [D23.101]
Antigens, Differentiation [D23.101.100]
Antigens, CD [D23.101.100.110]
Receptors, Interleukin-7 [D23.101.100.110.715]

Below are MeSH descriptors whose meaning is related to "Receptors, Interleukin-7".

Below are MeSH descriptors whose meaning is more specific than "Receptors, Interleukin-7".

Receptors, Interleukin-7
Interleukin Receptor Common gamma Subunit
Interleukin-7 Receptor alpha Subunit

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, Interleukin-7" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Interleukin-7" was a major or minor topic of these publication.

Bar chart showing 27 publications over 16 distinct years, with a maximum of 4 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	1	1
1996	0	2	2
2001	0	2	2
2004	0	2	2
2006	1	1	2
2008	1	1	2
2009	1	2	3
2010	1	0	1
2011	1	0	1
2012	1	0	1
2013	0	4	4
2015	1	0	1
2016	0	2	2
2017	1	0	1
2021	1	0	1
2022	0	1	1

Below are the most recent publications written about "Receptors, Interleukin-7" by people in Profiles.

Mutant IL7R collaborates with MYC to induce T-cell acute lymphoblastic leukemia. Leukemia. 2022 06; 36(6):1533-1540.

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Activated interleukin-7 receptor signaling drives B-cell acute lymphoblastic leukemia in mice. Leukemia. 2022 01; 36(1):42-57.

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A hierarchy of affinities between cytokine receptors and the common gamma chain leads to pathway cross-talk. Sci Signal. 2018 04 03; 11(524).

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IL-15 sustains IL-7R-independent ILC2 and ILC3 development. Nat Commun. 2017 03 31; 8:14601.

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Interleukin-7 and -15 maintain pathogenic memory Th17 cells in autoimmunity. J Autoimmun. 2017 02; 77:96-103.

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IL-7 primes IL-17 in mucosal-associated invariant T (MAIT) cells, which contribute to the Th17-axis in ankylosing spondylitis. Ann Rheum Dis. 2016 Dec; 75(12):2124-2132.

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Decitabine enhances chemosensitivity of early T-cell precursor-acute lymphoblastic leukemia cell lines and patient-derived samples. Leuk Lymphoma. 2016 08; 57(8):1938-41.

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Effector CD8+ T-cell Engraftment and Antitumor Immunity in Lymphodepleted Hosts Is IL7Ra Dependent. Cancer Immunol Res. 2015 Dec; 3(12):1364-74.

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Targeted sequencing identifies associations between IL7R-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemia. Haematologica. 2015 Oct; 100(10):1301-10.

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Interferon beta treatment of multiple sclerosis increases serum interleukin-7. Mult Scler. 2014 Nov; 20(13):1727-36.

View in: PubMed

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